Abstract:
BACKGROUND:Diarrhea caused by opportunistic intestinal protozoa is a common problem in HIV infection. We aimed to establish the prevalence of Cryptosporidium, misrosporidia, and Isospora in HIV-infected people using a systematic review and meta-analysis, which is central to developing public policy and clinical services. METHODS:We searched PubMed, ScienceDirect, Google Scholar, Embase, Chinese Web of Knowledge, Wanfang, and Chongqing VIP databases for studies reporting Cryptosporidium, microsporidia, or Isospora infection in HIV-infected people. We extracted the numbers of people with HIV and protozoa infection, and estimated the pooled prevalence of parasite infection by a random effects model. RESULTS:Our research identified 131 studies that reported Cryptosporidium, microsporidia, and Isospora infection in HIV-infected people. We estimated the pooled prevalence to be 14.0% (3283/43,218; 95% CI: 13.0-15.0%) for Cryptosporidium, 11.8% (1090/18,006; 95% CI: 10.1-13.4%) for microsporidia, and 2.5% (788/105,922; 95% CI: 2.1-2.9%) for Isospora. A low prevalence of microsporidia and Isospora infection was found in high-income countries, and a high prevalence of Cryptosporidium and Isospora infection was found in sub-Saharan Africa. We also detected a high prevalence of Cryptosporidium, microsporidia, and Isospora infection in patients with diarrhea. Sensitivity analysis showed that three studies significantly affect the prevalence of Isospora, which was adjusted to 5.0% (469/8570; 95% CI: 4.1-5.9%) by excluding these studies. CONCLUSIONS:Our findings suggest that HIV-infected people have a high prevalence of Cryptosporidium, microsporidia, and Isospora infection in low-income countries and patients with diarrhea, especially in sub-Saharan Africa, reinforcing the importance of routine surveillance for opportunistic intestinal protozoa in HIV-infected people.
journal_name
Parasit Vectorsjournal_title
Parasites & vectorsauthors
Wang ZD,Liu Q,Liu HH,Li S,Zhang L,Zhao YK,Zhu XQdoi
10.1186/s13071-017-2558-xsubject
Has Abstractpub_date
2018-01-09 00:00:00pages
28issue
1issn
1756-3305pii
10.1186/s13071-017-2558-xjournal_volume
11pub_type
杂志文章,meta分析,评审abstract:BACKGROUND:Porcine cysticercosis is an emerging agricultural problem in sub-Saharan Africa. This has been documented primarily through cross-sectional studies, however detailed knowledge of the transmission dynamics of this disease in sub-Saharan Africa is lacking. This study aims to describe seasonal variations in ser...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-014-0574-7
更新日期:2014-12-04 00:00:00
abstract:BACKGROUND:In this study, a total of 426 human faecal samples were examined for the presence of Entamoeba histolytica, Entamoeba dispar, Entamoeba moshkovskii infection via a combination of microscopic examination and nested polymerase chain reaction (PCR) targeting 16S ribosomal RNA of Entamoeba species. METHODS:Faec...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-5-187
更新日期:2012-09-04 00:00:00
abstract:BACKGROUND:The tropical bed bug, Cimex hemipterus, is a serious indoor public health pest in tropical regions causing intense physical discomfort and mental distress to humans. At present, the application of insecticides is the major control strategy. The present study was designed to evaluate the development of resist...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-019-3565-x
更新日期:2019-06-21 00:00:00
abstract:BACKGROUND:Coccidiosis due to Eimeria spp. infections in lambs causes increased mortality and substantial production losses, and anticoccidials are important for control of the infection. Anticoccidial resistance has been reported in poultry and swine, and we recently described reduced toltrazuril efficacy in ovine Eim...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-018-2976-4
更新日期:2018-07-05 00:00:00
abstract:BACKGROUND:The basic function of the immune system is to protect an organism against infection in order to minimize the fitness costs of being infected. According to life-history theory, energy resources are in a trade-off between the costly demands of immunity and other physiological demands. Concerning fish, both phy...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-4-120
更新日期:2011-06-27 00:00:00
abstract:BACKGROUND:The argasid tick Ornithodoros erraticus is the vector of African swine fever virus and of several Borrelia species that cause human relapsing fever in the Iberian Peninsula. The tick midgut is part of the ectoparasite-host interface and expresses proteins that are vital for the survival of the tick. Midgut p...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-015-1148-z
更新日期:2015-10-12 00:00:00
abstract:BACKGROUND:Bed bugs (Heteroptera: Cimicidae) are a group of blood-feeding ectoparasites. They mainly specialize on bats and birds, but a few species are important human pests. They exhibit several unique adaptations for their parasitic lifestyle. Among those, bed bug aggregations represent a striking example of a sub-s...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-019-3659-5
更新日期:2019-08-13 00:00:00
abstract:BACKGROUND:Dengue has become the subject of public health programs worldwide. The lack of a vaccine and the high environmental risk of synthetic insecticides, arouse the interest in natural products against this vector. This study aimed to determine the chemical composition of the essential oil of ripe fruits and seeds...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-015-0746-0
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:The Smad proteins function in TGF-β signalling transduction. In the model nematode Caenorhabditis elegans, the co-Smad, DAF-3 mediates R-Smads and performs a central role in DAF-7 signal transduction, regulating dauer formation and reproductive processes. Considering the divergent evolutionary patterns of th...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-019-3855-3
更新日期:2019-12-27 00:00:00
abstract:BACKGROUND:In Egypt, liver flukes, Fasciola spp. (Digenea: Fasciolidae), have a serious impact on the farming industry and public health. Both Fasciola hepatica and Fasciola gigantica are known to occur in cattle, providing the opportunity for genetic recombination. Little is known on the identity and genetic variabili...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1898-2
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Genetic information for Toxoplasma gondii isolates from pigs in eastern, south, and southwestern regions of China has been reported previously. However, there are no data from pigs in the northeastern area of the country. To better understand the epidemiology of T. gondii, we determined the seroprevalence an...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1525-2
更新日期:2016-04-29 00:00:00
abstract:BACKGROUND:The studies reported here were conducted to ascertain the efficacy of imidacloprid/flumethrin incorporated in a slow-release matrix collar, against infestations of dogs by fleas, ticks, mites and lice. Efficacy was evaluated against the flea Ctenocephalides felis felis, the ticks Rhipicephalus sanguineus, Ix...
journal_title:Parasites & vectors
pub_type: 杂志文章,随机对照试验
doi:10.1186/1756-3305-5-102
更新日期:2012-05-30 00:00:00
abstract:BACKGROUND:Natural compounds from plants are known to provide a source of anthelmintic molecules. In previous studies, we have shown that plant extracts from the plant Picria fel-terrae Lour. and particular fractions thereof have activity against the free-living nematode Caenorhabditis elegans, causing quite pronounced...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-019-3429-4
更新日期:2019-04-25 00:00:00
abstract:BACKGROUND:Entomopathogenic fungi are potential candidates for use in integrated vector management and many isolates are compatible with synthetic and natural insecticides. Neem oil was tested separately and in combination with the entomopathogenic fungus Metarhizium anisopliae against larvae of the dengue vector Aedes...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-015-1280-9
更新日期:2015-12-30 00:00:00
abstract:BACKGROUND:Rickettsial diseases are considered important in public health due to their dispersal capacity determined by the particular characteristics of their reservoirs and/or vectors. Among the latter, fleas play an important role, since the vast majority of species parasitize wild and invasive rodents, so their det...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-020-04388-5
更新日期:2020-10-17 00:00:00
abstract:BACKGROUND:Tannin-rich plants have been examined as an alternative for controlling the gastrointestinal nematodes in ruminants. In vivo assays typically examine the anthelmintic activity in female fecundity and/or the adult worm burden, without considering other life-cycle stages or the impact on pasture contamination....
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1370-3
更新日期:2016-02-24 00:00:00
abstract:BACKGROUND:Quantification of malaria heterogeneity is very challenging, partly because of the underlying characteristics of mosquitoes and also because malaria is an environmentally driven disease. Furthermore, in order to assess the spatial and seasonal variability in malaria transmission, vector data need to be colle...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-015-0679-7
更新日期:2015-02-22 00:00:00
abstract:BACKGROUND:The present study was conducted to investigate the serological survey of Toxoplasma antibodies in local.horses from three major regions: a neighbourhood of a city in the North (Sidi Thabet), a neighbourhood of a city on the coast (Monastir) and a neighbourhood of a city in the middle (Battan) of Tunisia (Nor...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-4-218
更新日期:2011-11-22 00:00:00
abstract:BACKGROUND:Dengue is a serious public health problem worldwide, including in Selangor, Malaysia. Being an important vector of dengue virus, Aedes aegypti are subjected to control measures which rely heavily on the usage of insecticides. Evidently, insecticide resistance in Ae. aegypti, which arise from several differen...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-019-3472-1
更新日期:2019-05-16 00:00:00
abstract:BACKGROUND:Bovine besnoitiosis, caused by the protozoan Besnoitia besnoiti, reduces productivity and fertility of affected herds. Besnoitiosis continues to expand in Europe and no effective control tools are currently available. Experimental models are urgently needed. Herein, we describe for the first time the kinetic...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1405-9
更新日期:2016-02-29 00:00:00
abstract:BACKGROUND:The sibling species of the malaria mosquito, Anopheles gambiae (sensu stricto) and Anopheles coluzzii co-exist in many parts of West Africa and are thought to have recently diverged through a process of ecological speciation with gene flow. Divergent larval ecological adaptations, resulting in Genotype-by-En...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-020-04483-7
更新日期:2021-01-06 00:00:00
abstract:BACKGROUND:The intestinal epithelium plays a multifactorial role in mucosal defense. In this sense, augmented epithelial cell turnover appears as a potential effector mechanism for the rejection of intestinal-dwelling helminths. METHODS:A BrdU pulse-chase experiment was conducted to investigate the infection-induced a...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-015-0948-5
更新日期:2015-06-18 00:00:00
abstract:BACKGROUND:The efficacy of fluralaner for the treatment of Otodectes cynotis infestations in dogs and cats was evaluated after oral (dogs) or topical administration (dogs and cats). Twenty-four dogs and sixteen cats were experimentally infested with O. cynotis and randomly allocated to equal sized groups (n = 8/group)....
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1954-y
更新日期:2017-01-16 00:00:00
abstract:BACKGROUND:This study evaluated the exposure of dogs to three different Ehrlichia spp. in the south and central regions of the United States where vector-borne disease prevalence has been previously difficult to ascertain, particularly beyond the metropolitan areas. METHODS:Dog blood samples (n = 8,662) were submitted...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-5-29
更新日期:2012-02-08 00:00:00
abstract::Onchocerciasis (river blindness) is a blinding parasitic disease that threatens the health of approximately 120 million people worldwide. While 99% of the population at-risk for infection from onchocerciasis live in Africa, some 500,000 people in the Americas are also threatened by infection. A relatively recent arriv...
journal_title:Parasites & vectors
pub_type: 杂志文章,评审
doi:10.1186/1756-3305-4-205
更新日期:2011-10-25 00:00:00
abstract::We report a Trichinella britovi outbreak investigated during February-March 2016 in southern Italy. The source of infection was meat from infected wild boars that were illegally hunted and, hence, not submitted to post-mortem veterinary inspection. Thirty persons reported having eaten raw dried homemade sausages; five...
journal_title:Parasites & vectors
pub_type: 信件
doi:10.1186/s13071-017-2052-5
更新日期:2017-02-28 00:00:00
abstract:BACKGROUND:Taenia multiceps is a harmful tapeworm and its larval form (coenurus cerebralis) is the causative agent of coenurosis, a disease affecting the health of herbivores, resulting in great economic loss to animal husbandry. Heat-shock proteins (HSPs), expressed in all prokaryotes and eukaryotes, act as molecular ...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-019-3352-8
更新日期:2019-03-12 00:00:00
abstract:BACKGROUND:Blastocystis spp. are the most prevalent intestinal eukaryotes identified in humans, with at least 17 genetic subtypes (ST) based on genes coding for the small-subunit ribosomal RNA (18S). It has been argued that the 18S gene should not be the marker of choice to discriminate between STs of these strains bec...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-018-3141-9
更新日期:2018-10-29 00:00:00
abstract:BACKGROUND:The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infections are mostly aimed ...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-018-2656-4
更新日期:2018-01-31 00:00:00
abstract:BACKGROUND:Malaria vector control in Africa relies on insecticides targeting adult mosquito vectors via insecticide treated nets or indoor residual spraying. Despite the proven efficacy of these strategies, the emergence and rapid rise in insecticide resistance in malaria vectors raises many concerns about their sustai...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1354-3
更新日期:2016-02-05 00:00:00