Abstract:
BACKGROUND:To compare corneal hysteresis (CH) measurements between patients with glaucoma, ocular hypertension (OHT) and glaucoma-like optic discs (GLD)- defined as a cup to disc ratio greater than or equal to 0.6 with normal intraocular pressure (IOP) and visual fields. The secondary aim was to investigate whether corneal resistance factor (CRF) and central corneal thickness (CCT) differ between patient groups. METHODS:In this cross sectional study a total of 123 patients (one eye each) were recruited from a glaucoma outpatient department to undergo ocular response analyser (ORA) testing and ultrasound pachymetry as well as clinical examination. A One-way Analysis of Covariance (ANCOVA) was conducted to evaluate the mean difference in CH between the three diagnostic groups (glaucoma, OHT and GLD) correcting for potential confounding factors, IOP and age. Analysis was repeated for CRF and CCT. RESULTS:There was a significant difference in mean CH across the three diagnosis groups; F(2, 115) = 96.95; p < 0.001. Mean CH significantly higher for GLD compared to glaucoma (mean difference 1.83, p < 0.001), and significantly higher for OHT compared to glaucoma (mean difference 2.35, p < 0.001). Mean CH was slightly lower in patients with GLD than those with OHT but this difference was not statistically significant. A similar pattern was seen when the analysis was repeated for CRF and CCT. CONCLUSIONS:Higher CH in GLD and OHT compared to glaucoma suggests increased viscoelasticity of ocular tissues may have a protective role against glaucoma.
journal_name
BMC Ophthalmoljournal_title
BMC ophthalmologyauthors
Murphy ML,Pokrovskaya O,Galligan M,O'Brien Cdoi
10.1186/s12886-016-0396-9subject
Has Abstractpub_date
2017-01-10 00:00:00pages
1issue
1issn
1471-2415pii
10.1186/s12886-016-0396-9journal_volume
17pub_type
杂志文章abstract:BACKGROUND:A description of the diagnostic features of Miller Fisher syndrome. CASE PRESENTATION:The clinical presentation, investigation, and subsequent progress of our patient with clinical unilateral external ophthalmoplegia. CONCLUSION:Our case demonstrates the presentation of clinical unilateral external ophthal...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-7-7
更新日期:2007-04-17 00:00:00
abstract:BACKGROUND:The aim of this study was to investigate the changes in corneal epithelial thickness along the principle meridians of astigmatic corneas after six months of overnight spherical myopic orthokeratology (OK) lens wear. METHODS:This is a prospective study. Fifty-seven subjects with up to 1.50 diopters (D) of co...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01477-y
更新日期:2020-06-19 00:00:00
abstract:BACKGROUND:Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but life-threatening conditions that initially affect the skin and mucous membranes. The aim of this study was to compare the acute ocular manifestations between SJS and TEN. METHODS:The initial presenting ophthalmic records of pat...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-017-0464-9
更新日期:2017-05-12 00:00:00
abstract:BACKGROUND:The short-term effects of intravitreal ranibizumab (IVR) on diabetic macular edema (DME) remains unclear. We assessed the short-term effects of IVR on DME. METHODS:Eighteen eyes of 14 patients with DME were enrolled in this prospective interventional case series. After intravitreal ranibizumab was injected ...
journal_title:BMC ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12886-017-0420-8
更新日期:2017-03-14 00:00:00
abstract:BACKGROUND:Despite growing number of intraocular lens power calculation formulas, there is no evidence that these formulas have good predictive accuracy in pediatric, whose eyes are still undergoing rapid growth and refractive changes. This study is intended to compare the prediction error and the accuracy of predictab...
journal_title:BMC ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-2415-10-20
更新日期:2010-08-25 00:00:00
abstract:BACKGROUND:To investigate the expression and significance of mechanistic target of rapamycin complex 1(mTORC1) in diabetic retinopathy (DR), and to find new targets and new methods for the treatment of DR. METHODS:A DR rat model was prepared by general feeding combined with intraperitoneal injection of 10% streptozoto...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01553-3
更新日期:2020-07-20 00:00:00
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journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-13-55
更新日期:2013-10-16 00:00:00
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journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01696-3
更新日期:2020-10-19 00:00:00
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journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01738-w
更新日期:2020-12-02 00:00:00
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journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-015-0141-9
更新日期:2015-10-29 00:00:00
abstract:BACKGROUND:This study sought to identify factors associated with retinal detachment and retreatment of aggressive posterior retinopathy of prematurity (APROP) initially treated with intravitreal ranibizumab (IVR) injection as well as the efficacy of IVR treatment. METHODS:This was a retrospective study. A total of 83 ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0815-1
更新日期:2018-06-26 00:00:00
abstract:BACKGROUND:To compare the efficacy of phacoemulsification (PKE) combined with nonpenetrating deep sclerectomy (NPDS) with mitomycin C (MMC) versus XEN® gel stent with MMC. METHODS:In this nonrandomized, retrospective, comparative, single-center pilot study, 105 consecutive eyes of 75 patients with uncontrolled primary...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01492-z
更新日期:2020-06-16 00:00:00
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journal_title:BMC ophthalmology
pub_type: 杂志文章,meta分析
doi:10.1186/s12886-015-0048-5
更新日期:2015-06-20 00:00:00
abstract:BACKGROUND:To investigate the corneal biomechanical changes in primary open angle glaucoma (POAG) patients treated with long-term prostaglandin analogue (PGA). METHODS:One hundred eleven newly diagnosed POAG patients, including 43 high tension glaucoma (HTG) and 68 normal tension glaucoma (NTG), were measured by Corvi...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01693-6
更新日期:2020-10-20 00:00:00
abstract:BACKGROUND:To evaluate inner retinal dimples after peeling of the inner limiting membrane (ILM) for macular holes (lamellar macular hole [LMH] and full-thickness macular hole [FTMH]) via multiple imaging modes of spectral-domain optical coherence tomography (OCT) and to assess their relationship with preoperative vitre...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0828-9
更新日期:2018-06-27 00:00:00
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journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-017-0613-1
更新日期:2017-11-25 00:00:00
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journal_title:BMC ophthalmology
pub_type: 信件
doi:10.1186/1471-2415-11-19
更新日期:2011-08-04 00:00:00
abstract:PURPOSE:To investigate the dynamic changes of hyperreflective foci (HF) in diabetic macular edema (DME) patients during the intravitreal Conbercept treatment in China. METHODS:DME Patients receiving intravitreal Conbercept (IVC) injections during the year 2016-2017 were retrospectively investigated. Thirteen patients ...
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pub_type: 杂志文章
doi:10.1186/s12886-019-1168-0
更新日期:2019-07-23 00:00:00
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journal_title:BMC ophthalmology
pub_type: 杂志文章,多中心研究
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更新日期:2020-02-04 00:00:00
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pub_type: 杂志文章
doi:10.1186/1471-2415-12-15
更新日期:2012-06-18 00:00:00
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pub_type: 杂志文章
doi:10.1186/1471-2415-14-124
更新日期:2014-10-21 00:00:00
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journal_title:BMC ophthalmology
pub_type: 杂志文章
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更新日期:2020-06-11 00:00:00
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journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01725-1
更新日期:2020-11-20 00:00:00
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journal_title:BMC ophthalmology
pub_type: 杂志文章,评审
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更新日期:2016-08-03 00:00:00
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journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-11-33
更新日期:2011-11-15 00:00:00
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journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-017-0503-6
更新日期:2017-07-04 00:00:00
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journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-017-0476-5
更新日期:2017-05-19 00:00:00
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pub_type: 杂志文章,meta分析,评审
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更新日期:2017-12-28 00:00:00
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journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-14-88
更新日期:2014-07-02 00:00:00
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journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01564-0
更新日期:2020-11-17 00:00:00