Abstract:
:Gut microbes are active participants of host metabolism. At birth, child physiology is committed towards healthiness or sickness depending, in part, on maternal condition (i.e. lean vs obesity) and delivery. Finally, changes from breastfeeding to solid food also account to define gut microbiota ecology in adulthood. Nowadays, alterations of gut microbiota, named dysbiosis, are acquired risk factors for multiple diseases, especially type 2 diabetes and obesity. Despite important evidence linking nutrition to dysbiosis to energetic dysmetabolism, molecular mechanisms for causality are still missing. That the status of gut microbiota of mother and child is crucial for future diseases is witnessed by adulthood overweight and obesity observed in children with dysbiosis. In this short review we highlight the importance of early life events related to the microbiota and their impact on future adult disease risk. Therefore, our effort to treat or prevent metabolic diseases should be addressed towards early or previous life steps, when microbial decisions are going to affect our metabolic fate.
journal_name
Pediatr Obesjournal_title
Pediatric obesityauthors
Serino M,Nicolas S,Trabelsi MS,Burcelin R,Blasco-Baque Vdoi
10.1111/ijpo.12146subject
Has Abstractpub_date
2017-08-01 00:00:00pages
e28-e32issue
4eissn
2047-6302issn
2047-6310journal_volume
12pub_type
杂志文章,评审abstract:OBJECTIVE:This study investigated if levels of allostatic load (ALoad) differed according to race/ethnicity in children and if ALoad was associated with obesity-related measures. METHODS:A multiethnic sample of 307 children aged seven to 12 was evaluated, composed of 39% European American (EA), 35% African American (A...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12501
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE:To examine associations between consumption of low-calorie sweetened beverages (LCSBs), sugar, and total energy intake in children in the United States. METHODS:We used 24-hour dietary recalls from 7026 children enrolled in the National Health and Nutrition Examination Survey (NHANES) 2011 to 2016 to assess ...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12535
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:Consumption of added sugars is linked to excess adiposity in older age groups and breastfeeding has been shown to protect against later obesity. OBJECTIVES:This investigation aimed to determine whether intake of added sugars associates with rapid weight gain in individuals under 2 years of age, if intake of...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12728
更新日期:2020-09-23 00:00:00
abstract:BACKGROUND:The international (International Obesity Task Force; IOTF) body mass index (BMI) cut-offs are widely used to assess the prevalence of child overweight, obesity and thinness. Based on data from six countries fitted by the LMS method, they link BMI values at 18 years (16, 17, 18.5, 25 and 30 kg m(-2)) to child...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/j.2047-6310.2012.00064.x
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Hepatic steatosis (HS) is currently the most prevalent hepatic disease in paediatric population and a major risk factor for type 2 diabetes and cardiovascular diseases. The proper identification of children with HS is therefore of great public health interest. OBJECTIVE:To develop a new prediction score usi...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12770
更新日期:2021-01-05 00:00:00
abstract:OBJECTIVE:Our aim is to determine the effect of paced eating, exposure to an educational programme that promotes healthy eating habits and allowing the satiety reflex to limit food intake in controlling weight gain in healthy adolescents. METHODS:Fifty-four healthy individuals consisting of 18 adolescent girls and 36 ...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12091
更新日期:2016-12-01 00:00:00
abstract:PURPOSE:Insulin responses to oral and intravenous glucose markedly differ by ethnicity. This study examined whether ethnic differences in pancreatic insulin secretion, hepatic insulin extraction and clearance explain these disparate findings in 35 obese African-American and 41 Latina girls (Tanner Stages: IV-V; ages: 1...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/j.2047-6310.2013.00184.x
更新日期:2013-12-01 00:00:00
abstract::Childhood obesity is associated with a pro-atherogenic phenotype contributing to increased cardiovascular disease (CVD) risk. This single-arm pilot study examined the effects of a lifestyle intervention on lipoprotein particle size and cholesterol distribution in obese Latino adolescents. Fifteen obese Latino adolesce...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/j.2047-6310.2013.00162.x
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:Dietary factors seem to influence telomere length. Moreover, associations between changes in adiposity indices and telomere length (TL) have been found in intervention studies. OBJECTIVE:We evaluated changes in two diet quality indices and their association with TL in children with abdominal obesity in a 12...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12661
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:The incidence of type 2 diabetes mellitus (T2D) is increasing in youth, yet little is known about the underlying pathophysiology. Decreased insulin suppression of lipolysis and elevated non-esterified free fatty acid (NEFA) concentrations are known to be associated with insulin resistance and T2D in adults, ...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/j.2047-6310.2013.00189.x
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:To describe total and trimester-specific gestational weight gain (GWG) among low-income Hispanic women and determine whether these GWG exposures are associated with infant anthropometric outcomes at birth and 6 months. STUDY DESIGN:Data were from 448 mother-infant pairs enrolled in the Starting Early child o...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12589
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Increases in portion size are thought by many to promote obesity in children. However, this relationship remains unclear. Here, we explore the extent to which a child's BMI is predicted both by parental beliefs about their child's ideal and maximum portion size and/or by the child's own beliefs. METHODS:Par...
journal_title:Pediatric obesity
pub_type: 杂志文章,随机对照试验
doi:10.1111/ijpo.12218
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:The data regarding prospective associations between physical activity (PA) and adiposity in youth are inconsistent. OBJECTIVE:The objective of this study was to investigate associations between baseline levels of objectively measured PA and changes in adiposity over 2.5 years from mid-to-late adolescence. ...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12031
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Population-specific accelerometer cut-points are required to accurately determine the accumulation of physical activity of various intensities. OBJECTIVES:A calibration study was conducted (i) to determine the cut-points for the ActiGraph GT3X+, non-dominant, wrist-mounted accelerometer in children aged 8-1...
journal_title:Pediatric obesity
pub_type: 杂志文章,多中心研究
doi:10.1111/ijpo.12033
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to assess overweight and obesity status transition probabilities using first-order Markov transition models applied to elementary school children. METHOD:Complete longitudinal data across 11 assessments were available from 1494 elementary school children (from 7599 students in...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12025
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVES:The objectives of this study were twofold - (i) to assess the agreement between self-reported waist circumference (SRWC) and assessor measured waist circumference (MWC) and (ii) to evaluate the diagnostic ability of SRWC for classifying (i) a clustering of cardiometabolic risk factors (CMRFs) and (ii) overwe...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/j.2047-6310.2011.00017.x
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Overt or subclinical hypothyroidism is a common finding in adult populations affected by non-alcoholic fatty liver disease (NAFLD). Currently, there are only sparse data available on the association of thyroid dysfunction and NAFLD in obese children and adolescents. OBJECTIVE:The study aims to investigate t...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12110
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Non-alcoholic fatty liver disease (NAFLD), prediabetes and type 2 diabetes mellitus are known to be closely linked with obesity as early as during childhood. OBJECTIVES:The study aimed to determine the prevalence of prediabetes and T2DM in children with obesity with or without increased transaminases. METH...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12601
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:In the USA, half of children are regularly cared for before or after school by someone other than a parent. OBJECTIVE:Describe the relationship between childcare arrangements and obesity among school-aged children. METHODS:Data are from the fifth-grade wave of the Early Childhood Longitudinal Study - Kinde...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12107
更新日期:2017-02-01 00:00:00
abstract::The consumption of high-fructose corn syrup (HFCS) beverages has increased since the 1970s. At the same time, childhood obesity is on the rise, causing children to be at risk of heart disease, diabetes and other diseases. Healthcare providers have attributed childhood obesity to the consumption of HFCS in the form of ...
journal_title:Pediatric obesity
pub_type: 杂志文章,评审
doi:10.1111/j.2047-6310.2013.00173.x
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVES:Sagittal diameter (SAD) has been reported to correlate to visceral fat and cardiovascular risk factors. SAD is measured with the individual lying down, halfway between the lower rib margin and the iliac crest; it represents the mid-height of the abdomen. The aim of this study was to validate SAD measured usi...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/j.2047-6310.2012.00095.x
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:There are no academic studies that characterize advertisements directed at children from the companies that signed the self-regulation. OBJECTIVE:The aim of this paper was to assess the extent and nature of food advertisements and the persuasive techniques used to market unhealthy food and beverages (UFB) t...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12144
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Drink personalization (featuring names on bottle labels) has been used by soft drink companies to make their drinks attractive to children, potentially increasing consumption. To date, no publically available research has evaluated the influence of personalization on children's drink choices. OBJECTIVES:To ...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12193
更新日期:2018-01-01 00:00:00
abstract::Mobile health (mHealth) is a relatively nascent field, with a variety of technologies being explored and developed. Because of the explosive growth in this field, it is of interest to examine the design, development and efficacy of various interventions as research becomes available. This systematic review examines cu...
journal_title:Pediatric obesity
pub_type: 杂志文章,评审
doi:10.1111/ijpo.12002
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Emerging adulthood is a critical time for excess weight gain. Risk can be masked if recommended overweight and obesity cut-points for Asians are not employed. OBJECTIVES:To determine the associations among sociodemographic factors and occurrence of overweight and obesity among normal weight 18-year olds. M...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12173
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:In some previous studies direct associations between intake of soft drinks, sugar-sweetened beverages and adiposity have been reported. The majority of these studies were, however, conducted in the USA and it is uncertain if the results are applicable to non-US countries. OBJECTIVE:To assess the association...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/j.2047-6310.2013.00170.x
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVE:This study aimed to examine physical activity (PA) patterns in children with autism spectrum disorder (ASD) as well as to address PA determinant factors by employing triaxial accelerometry. METHODS:In a school-based cross-sectional study of 80 children and adolescents with ASD (mean = 9.6, standard deviation...
journal_title:Pediatric obesity
pub_type: 杂志文章,多中心研究
doi:10.1111/j.2047-6310.2012.00101.x
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:Biochemical predictors of infants' growth changes are not available. OBJECTIVES:We tested whether retinol-binding protein (RBP), docosahexaenoic acid and insulin (I) measured within 72 h from birth are associated with growth changes in infants born to mothers with gestational diabetes mellitus (GDM). METHO...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/j.2047-6310.2012.00097.x
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Child emotional overeating is a risk factor for obesity that is learned in the home environment. Parents' use of food to soothe child distress may contribute to the development of children's emotional overeating. OBJECTIVES:To examine the effect of a responsive parenting (RP) intervention on mother-reported...
journal_title:Pediatric obesity
pub_type: 杂志文章,随机对照试验
doi:10.1111/ijpo.12645
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:The incidence of childhood obesity and associated comorbidities are on an increasing trend worldwide. More than 340 million children and adolescents aged between 5 and 19 years old were overweight or had obesity in 2016, from which over 124 million children and adolescents (6% of girls and 8% of boys) had ob...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12653
更新日期:2020-09-01 00:00:00