'Some anti-malarials are too strong for your body, they will harm you.' Socio-cultural factors influencing pregnant women's adherence to anti-malarial treatment in rural Gambia.

abstract：BACKGROUND:Resistance to multiple classes of insecticides has been detected in the malaria vector Anopheles albimanus in northwest Peru. Acetylcholinesterase (AChE) insensitivity has previously been associated with resistance to organophosphate (OP) and carbamate (CA) insecticides in arthropods. A single point mutation...

journal_title：Malaria journal

authors： Liebman KA,Pinto J,Valle J,Palomino M,Vizcaino L,Brogdon W,Lenhart A

更新日期：2015-02-14 00:00:00

abstract：:The classic formulae in malaria epidemiology are reviewed that relate entomological parameters to malaria transmission, including mosquito survivorship and age-at-infection, the stability index (S), the human blood index (HBI), proportion of infected mosquitoes, the sporozoite rate, the entomological inoculation rate ...

journal_title：Malaria journal

authors： Smith DL,McKenzie FE

更新日期：2004-06-04 00:00:00

abstract：BACKGROUND:Chloroquine-resistant Plasmodium falciparum was first described in the Republic of Vanuatu in the early 1980s. In 1991, the Vanuatu Ministry of Health instituted new treatment guidelines for uncomplicated P. falciparum infection consisting of chloroquine/sulphadoxine-pyrimethamine combination therapy. Chloro...

journal_title：Malaria journal

authors： Kinzer MH,Chand K,Basri H,Lederman ER,Susanti AI,Elyazar I,Taleo G,Rogers WO,Bangs MJ,Maguire JD

更新日期：2010-04-06 00:00:00

abstract：BACKGROUND:Insecticide resistance is the major emerging challenge facing the malaria vector control programmes in Tanzania. Proper monitoring and detection is of paramount importance guiding the vector control programmes. This paper presents the effect of mosquito aging on insecticide resistance status in Anopheles ara...

journal_title：Malaria journal

authors： Mbepera S,Nkwengulila G,Peter R,Mausa EA,Mahande AM,Coetzee M,Kweka EJ

更新日期：2017-09-11 00:00:00

abstract：BACKGROUND:Nicotinamide adenine dinucleotide (NAD+) is an essential molecule in the energy metabolism of living beings, and it has various cellular functions. The main enzyme in the biosynthesis of this nucleotide is nicotinamide/nicotinate mononucleotide adenylyltransferase (NMNAT, EC 2.7.7.1/18) because it is the con...

journal_title：Malaria journal

authors： Nieto CA,Sánchez LM,Sánchez DM,Díaz GJ,Ramírez MH

更新日期：2018-04-11 00:00:00

abstract：BACKGROUND:Surprisingly little is known about the geographical overlap between malaria and other tropical diseases, including helminth infections. This is despite the potential public health importance of co-infection and synergistic opportunities for control. METHODS:Statistical models are presented that predict the ...

journal_title：Malaria journal

authors： Brooker S,Clements AC,Hotez PJ,Hay SI,Tatem AJ,Bundy DA,Snow RW

更新日期：2006-11-03 00:00:00

abstract：BACKGROUND:Passerine birds are frequently infected with diverse haemosporidian parasites. While infections are traditionally considered benign in wild birds, recent studies demonstrated mortalities of passerine species due to exo-erythrocytic development of the parasites, which can damage organs in affected hosts. Howe...

journal_title：Malaria journal

authors： Himmel T,Harl J,Pfanner S,Nedorost N,Nowotny N,Weissenböck H

更新日期：2020-02-12 00:00:00

abstract：BACKGROUND:Anti-malarial herbal preparations (HPs) continue to enjoy high patronage in Ghana despite reports that the artemisinin-based combination therapy (ACT), the recommended first choice for treatment of uncomplicated malaria in the country, remains efficacious. A major issue with the use of these preparations is ...

journal_title：Malaria journal

authors： Wilmot D,Ameyaw EO,Amoako-Sakyi D,Boampong JN,Quashie NB

更新日期：2017-03-04 00:00:00

abstract：BACKGROUND:Successful reduction of malaria transmission to very low levels has made Isabel Province, Solomon Islands, a target for early elimination by 2014. High malaria transmission in neighbouring provinces and the potential for local asymptomatic infections to cause malaria resurgence highlights the need for sub-na...

journal_title：Malaria journal

authors： Atkinson JA,Johnson ML,Wijesinghe R,Bobogare A,Losi L,O'Sullivan M,Yamaguchi Y,Kenilorea G,Vallely A,Cheng Q,Ebringer A,Bain L,Gray K,Harris I,Whittaker M,Reid H,Clements A,Shanks D

更新日期：2012-03-30 00:00:00

abstract：BACKGROUND:Plasmodium falciparum-infected erythrocytes sequester in the microcirculation due to interaction between surface-expressed parasite proteins and endothelial receptors. Endothelial cells are covered in a carbohydrate-rich glycocalyx that shields against undesired leukocyte adhesion. It was investigated if the...

journal_title：Malaria journal

authors： Hempel C,Wang CW,Kurtzhals JAL,Staalsø T

更新日期：2017-05-10 00:00:00

abstract：BACKGROUND:Intermittent preventive treatment with sulphadoxine-pyrimethamine (SP) is recommended for reducing the risk of malaria in pregnancy and its consequences on mothers and babies (IPTp-SP). Indicators of implementation and effects of IPTp-SP were collected in a rural clinic in Southern Senegal. METHODS:Women se...

journal_title：Malaria journal

authors： Olliaro PL,Delenne H,Cisse M,Badiane M,Olliaro A,Vaillant M,Brasseur P

更新日期：2008-11-07 00:00:00

abstract：BACKGROUND:Models of Plasmodium falciparum malaria epidemiology that provide realistic quantitative predictions of likely epidemiological outcomes of existing vector control strategies have the potential to assist in planning for the control and elimination of malaria. This work investigates the applicability of mathem...

journal_title：Malaria journal

authors： Stuckey EM,Stevenson JC,Cooke MK,Owaga C,Marube E,Oando G,Hardy D,Drakeley C,Smith TA,Cox J,Chitnis N

更新日期：2012-10-29 00:00:00

abstract：:Natural compounds, mostly from plants, have been the mainstay of traditional medicine for thousands of years. They have also been the source of lead compounds for modern medicine, but the extent of mining of natural compounds for such leads decreased during the second half of the 20th century. The advantage of natural...

journal_title：Malaria journal

authors： Ginsburg H,Deharo E

更新日期：2011-03-15 00:00:00

abstract：BACKGROUND:The potential emergence and spread of resistance to artemisinins in the Plasmodium falciparum malaria parasite constitutes a major global health threat. Hence, improving the efficacy of artemisinins and of artemisinin-based combination therapy (ACT) represents a major short-term goal in the global fight agai...

journal_title：Malaria journal

authors： Moradin N,Torre S,Gauthier S,Tam M,Hawari J,Vandercruyssen K,De Spiegeleer B,Fortin A,Stevenson MM,Gros P

更新日期：2016-05-06 00:00:00

abstract：BACKGROUND:In areas with ongoing malaria transmission, strategies to clear parasites from populations can reduce infection and transmission. The objective of this paper was to describe a malaria mass testing and treatment (MTAT) intervention implemented in six kebeles (villages) in Amhara Region, Ethiopia, at the begin...

journal_title：Malaria journal

authors： Scott CA,Yeshiwondim AK,Serda B,Guinovart C,Tesfay BH,Agmas A,Zeleke MT,Guesses GS,Ayenew AL,Workie WM,Steketee RW,Earle D,Bezabih B,Getachew A

更新日期：2016-06-02 00:00:00

abstract：BACKGROUND:As Swaziland progresses towards national malaria elimination, the importation of parasites into receptive areas becomes increasingly important. Imported infections have the potential to instigate local transmission and sustain local parasite reservoirs. METHODS:Travel histories from Swaziland's routine surv...

journal_title：Malaria journal

authors： Tejedor-Garavito N,Dlamini N,Pindolia D,Soble A,Ruktanonchai NW,Alegana V,Le Menach A,Ntshalintshali N,Dlamini B,Smith DL,Tatem AJ,Kunene S

更新日期：2017-09-08 00:00:00

abstract：BACKGROUND:Polymorphism in the pfcrt gene underlies Plasmodium falciparum chloroquine resistance (CQR), as sensitive strains consistently carry lysine (K), while CQR strains carry threonine (T) at the codon 76. Previous studies have shown that microsatellite (MS) haplotype variation can be used to study the evolution o...

journal_title：Malaria journal

authors： DaRe JT,Mehlotra RK,Michon P,Mueller I,Reeder J,Sharma YD,Stoneking M,Zimmerman PA

更新日期：2007-03-21 00:00:00

abstract：BACKGROUND:Due to the development of resistance to synthetic insecticides, adverse effects to human health, non-target organisms and the environment, there is an urgent need to develop new insecticides, which are effective, safe, biodegrable and target-specific. This study was undertaken to evaluate the adulticidal act...

journal_title：Malaria journal

authors： Mavundza EJ,Maharaj R,Chukwujekwu JC,Finnie JF,Van Staden J

更新日期：2014-05-06 00:00:00

abstract：BACKGROUND:Health care demand studies help to examine the behaviour of individuals and households during illnesses. Few of existing health care demand studies examine the choice of treatment services for childhood illnesses. Besides, in their analyses, many of the existing studies compare alternative treatment options ...

journal_title：Malaria journal

authors： Nonvignon J,Aikins MK,Chinbuah MA,Abbey M,Gyapong M,Garshong BN,Fia S,Gyapong JO

更新日期：2010-06-28 00:00:00

abstract：BACKGROUND:Many malaria-related studies depend on infected red blood cells (iRBCs) as fundamental material; however, infected blood samples from human or animal models include leukocytes (white blood cells or WBCs), especially difficult to separate from iRBCs in cases involving Plasmodium vivax. These host WBCs are a s...

journal_title：Malaria journal

authors： Tao ZY,Xia H,Cao J,Gao Q

更新日期：2011-08-25 00:00:00

abstract：BACKGROUND:The use of anti-malarial drug combinations with artemisinin or with one of its derivatives is now widely recommended to overcome drug resistance in falciparum as well as vivax malaria. The fixed oral dose artemisinin-naphthoquine combination (ANQ, ARCO) is a newer artemisinin-based combination (ACT) therapy ...

journal_title：Malaria journal

authors： Hombhanje FW,Linge D,Saweri A,Kuanch C,Jones R,Toraso S,Geita J,Masta A,Kevau I,Hiawalyer G,Sapuri M

更新日期：2009-08-12 00:00:00

abstract：BACKGROUND:There has been much debate about the appropriate statistical methodology for the evaluation of malaria field studies and the challenges in interpreting data arising from these trials. METHODS:The present paper describes, for a pivotal phase III efficacy of the RTS, S/AS01 malaria vaccine, the methods of the...

journal_title：Malaria journal

authors： Lievens M,Aponte JJ,Williamson J,Mmbando B,Mohamed A,Bejon P,Leach A

更新日期：2011-08-04 00:00:00

abstract：BACKGROUND:Glucose-6-phosphate dehydrogenase (G6PD) deficiency is currently a threat to malaria elimination due to risk of primaquine-induced haemolysis in G6PD deficient individuals. The World Health Organization (WHO) recommends G6PD screening before providing primaquine as a radical treatment against vivax malaria. ...

journal_title：Malaria journal

authors： Marasini B,Lal BK,Thapa S,Awasthi KR,Bajracharya B,Khanal P,Neupane S,Jha SN,Acharya S,Iama S,Koirala M,Koirala D,Bhandari S,Mahato RK,Chaudhary A,Ghimire P,Magar RG,Bhattarai RK,Gornsawun G,Penpitchaporn P,Bancon

更新日期：2020-08-12 00:00:00

abstract：BACKGROUND:Kohat district is one of the medium intensity malaria transmission areas in Pakistan where asymptomatic carriers are likely to form a reservoir of infection. This study was done to explore the possibility of using microscopy, rapid diagnostic testing (RDT), real time polymerase chain reaction (RT-PCR) and RT...

journal_title：Malaria journal

authors： Naeem MA,Ahmed S,Khan SA

更新日期：2018-01-22 00:00:00

abstract：INTRODUCTION:Malaria is the largest cause of health services attendance, hospital admissions and child deaths in Tanzania. At the Abuja Summit in April 2000 Tanzania committed itself to protect 60% of its population at high risk of malaria by 2005. The country is, therefore, determined to ensure that sustainable malari...

journal_title：Malaria journal

authors： Magesa SM,Lengeler C,deSavigny D,Miller JE,Njau RJ,Kramer K,Kitua A,Mwita A

更新日期：2005-07-22 00:00:00

abstract：BACKGROUND:This study aimed to identify factors at individual and community level influencing insecticide-treated net (ITN) usage among groups of women of childbearing age (WOCBA) in Malawi. METHODS:Factors influencing ITN usage in Malawi were assessed through interviews with 16,130 WOCBA (15-49 years) across 850 comm...

journal_title：Malaria journal

authors： Nkoka O,Chuang TW,Chuang KY,Chen YH

更新日期：2018-10-19 00:00:00

abstract：BACKGROUND:Certain species of macaques are natural hosts of Plasmodium knowlesi and Plasmodium cynomolgi, which can both cause malaria in humans, and Plasmodium inui, which can be experimentally transmitted to humans. A significant number of zoonotic malaria cases have been reported in humans throughout Southeast Asia,...

journal_title：Malaria journal

authors： Fungfuang W,Udom C,Tongthainan D,Kadir KA,Singh B

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Malaria vector control in Tanzania is based on use of long-lasting insecticide treated nets (LLINs) and indoor residual spraying (IRS), which both rely on the use of chemical insecticides. The effectiveness of these control tools is endangered by the development of insecticide resistance in the major malaria...

journal_title：Malaria journal

authors： Kisinza WN,Nkya TE,Kabula B,Overgaard HJ,Massue DJ,Mageni Z,Greer G,Kaspar N,Mohamed M,Reithinger R,Moore S,Lorenz LM,Magesa S

更新日期：2017-10-30 00:00:00

abstract：BACKGROUND:Malaria is a major health problem in sub-Saharan Africa where over 90% of the world's malaria cases occur. Artemisinin-based combination therapy (ACT) is recommended by the World Health Organization as first-line and second-line treatments for uncomplicated falciparum malaria. However, there are a growing nu...

journal_title：Malaria journal

authors： Ndwigah S,Stergachis A,Abuga K,Mugo H,Kibwage I

更新日期：2018-09-15 00:00:00

abstract：BACKGROUND:Malaria prevalence has recently declined markedly in many parts of Tanzania and other sub-Saharan African countries due to scaling-up of control interventions including more efficient treatment regimens (e.g. artemisinin-based combination therapy) and insecticide-treated bed nets. Although continued molecula...

journal_title：Malaria journal

authors： Ishengoma DS,Lwitiho S,Madebe RA,Nyagonde N,Persson O,Vestergaard LS,Bygbjerg IC,Lemnge MM,Alifrangis M

更新日期：2011-01-12 00:00:00