Abstract：
BACKGROUND:Lyme borreliosis is the most common tick-borne human disease and is caused by Borrelia burgdorferi sensu lato (s.l.). Borrelia miyamotoi, a relapsing fever spirochaete, is transmitted transovarially, whereas this has not been shown for B. burgdorferi (s.l). Therefore, B. burgdorferi (s.l) is considered to cycle from nymphs to larvae through vertebrates. Larvae of Ixodes ricinus are occasionally B. burgdorferi (s.l) infected, but their vector competence has never been studied. METHODS:We challenged 20 laboratory mice with field-collected larvae of I. ricinus. A subset of these larvae was analysed for infections with B. burgdorferi (s.l) and B. miyamotoi. After three to four challenges, mice were sacrificed and skin and spleen samples were analysed for infection by PCR and culture. RESULTS:Field-collected larvae were naturally infected with B. burgdorferi (s.l) (0.62%) and B. miyamotoi (2.0%). Two mice acquired a B. afzelii infection and four mice acquired a B. miyamotoi infection during the larval challenges. CONCLUSION:We showed that larvae of I. ricinus transmit B. afzelii and B. miyamotoi to rodents and calculated that rodents have a considerable chance of acquiring infections from larvae compared to nymphs. As a result, B. afzelii can cycle between larvae through rodents. Our findings further imply that larval bites on humans, which easily go unnoticed, can cause Lyme borreliosis and Borrelia miyamotoi disease.
journal_name
Parasit Vectorsjournal_title
Parasites & vectorsauthors
van Duijvendijk G,Coipan C,Wagemakers A,Fonville M,Ersöz J,Oei A,Földvári G,Hovius J,Takken W,Sprong Hdoi
10.1186/s13071-016-1389-5subject
Has Abstractpub_date
2016-02-20 00:00:00pages
97issn
1756-3305pii
10.1186/s13071-016-1389-5journal_volume
9pub_type
杂志文章abstract：: The brown dog tick (Rhipicephalus sanguineus) is the most widespread tick in the world and a well-recognized vector of many pathogens affecting dogs and occasionally humans. This tick can be found on dogs living in both urban and rural areas, being highly adapted to live within human dwellings and being active throug...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-3-26
更新日期：2010-04-08 00:00:00
abstract：BACKGROUND:Two hemoplasma species, Mycoplasma suis and M. parvum, previously known as Eperythrozoon suis and E. parvum, respectively, have been identified in pigs. Swine hemoplasmosis is a global problem, and M. suis infection results in economic losses to pig producers worldwide. This study investigated the frequency ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-019-3638-x
更新日期：2019-07-29 00:00:00
abstract：BACKGROUND:The Cqm1 α-glucosidase of Culex quinquefasciatus larvae acts as the midgut receptor for the binary toxin of the biolarvicide Lysinibacillus sphaericus. Mutations within the cqm1 gene can code for aberrant polypeptides that can no longer be properly expressed or bind to the toxin, leading to insect resistance...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1347-2
更新日期：2016-02-04 00:00:00
abstract：:Acaricidal (tick) and insecticidal (flea) efficacy of systemically and cutaneously distributed ectoparasiticide products for dogs are compared based on permethrin and fluralaner as representative molecules. Results of efficacy studies against fleas and ticks are reviewed that show generally good to excellent results. ...
journal_title：Parasites & vectors
pub_type： 杂志文章,评审
doi：10.1186/s13071-016-1719-7
更新日期：2016-08-08 00:00:00
abstract：BACKGROUND:Prevalence of lymphatic filariasis (LF) antigen in American Samoa was 16.5% in 1999. Seven rounds of mass drug administration (MDA) programmes between 2000 and 2006 reduced antigen prevalence to 2.3%. The most efficient methods of surveillance after MDA are not clear, but testing specific at-risk groups such...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-3996-4
更新日期：2020-03-12 00:00:00
abstract：BACKGROUND:National deworming programmes rely almost exclusively on mass drug administration (MDA) to children to control morbidity caused by these parasitic infections. The provision of other interventions, consisting of preventive chemotherapy at high population level coverage together with water, sanitation and hygi...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-019-3757-4
更新日期：2019-10-29 00:00:00
abstract：BACKGROUND:Free-living amoebae of the genus Acanthamoeba are cosmopolitan, widely distributed protozoans that cause a severe, vision-threatening corneal infection known as Acanthamoeba keratitis (AK). The majority of the increasing number of AK cases are associated with contact lens use. Appropriate eye hygiene and eff...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04453-z
更新日期：2020-12-22 00:00:00
abstract：BACKGROUND:Mathematical models of parasite transmission can help integrate a large body of information into a consistent framework, which can then be used for gaining mechanistic insights and making predictions. However, uncertainty, spatial variability and complexity, can hamper the use of such models for decision mak...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-1132-7
更新日期：2015-10-22 00:00:00
abstract：BACKGROUND:The present study focuses on both long- and short-term malaria transmission in Eritrea and investigates the risk factors. Annual aggregates of information on malaria cases, deaths, diagnostics and control interventions from 2001 to 2008 and monthly reported data from 2009 to 2017 were obtained from the Natio...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-3974-x
更新日期：2020-03-12 00:00:00
abstract：BACKGROUND:Blackflies (Diptera: Simuliidae) are known as effective vectors of human and animal pathogens, worldwide. We have already indicated that some individuals in the Simulium turgaicum complex are annoying pests of humans and livestock in the Aras River Basin, Iran. However, there is no evidence of host preferenc...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04432-4
更新日期：2020-11-04 00:00:00
abstract：BACKGROUND:Malaria is the most important vector-borne disease in the world. Epidemiological and ecological studies of malaria traditionally utilize detection of Plasmodium sporozoites in whole mosquitoes or salivary glands by microscopy or serological or molecular assays. However, these methods are labor-intensive, and...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-019-3610-9
更新日期：2019-07-18 00:00:00
abstract：BACKGROUND:As resistance to insecticides increases in disease vectors, it has become exceedingly important to monitor populations for susceptibility. Most studies of field populations of Aedes aegypti have largely characterized resistance patterns at the spatial scale of the city or country, which may not be completely...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-3275-9
更新日期：2019-01-09 00:00:00
abstract：BACKGROUND:The prevalence of bovine babesiosis caused by Babesia divergens has been declining during the past decades in northeastern Hungary, and no cases have been observed since 2008. Infections of cattle with B. major and Theileria buffeli were hitherto reported in southern and western Europe. In other parts of the...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-7-434
更新日期：2014-09-11 00:00:00
abstract：BACKGROUND:Bovine besnoitiosis, caused by the apicomplexan parasite Besnoitia besnoiti, is a chronic and debilitating cattle disease that notably impairs fertility. Acutely infected bulls may develop respiratory signs and orchitis, and sterility has been reported in chronic infections. However, the pathogenesis of acut...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-3959-9
更新日期：2020-03-02 00:00:00
abstract：BACKGROUND:Most studies on Enterocytozoon bieneusi are conducted based on the internal transcribed spacer (ITS) region of the rRNA gene, whereas some have examined E. bieneusi population structures. Currently, the population genetics of this pathogen in giant panda remains unknown. The objective of this study was to de...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2459-z
更新日期：2017-10-18 00:00:00
abstract：BACKGROUND:The frequent outbreaks of human trichinellosis globally underscore the need to develop effective vaccine. We hypothesized that a novel vaccine could improve vaccine efficacy against Trichinella spiralis. METHODS:In this study, we developed virus-like particles (VLPs) containing the 53 KDa excretory/secretor...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1662-7
更新日期：2016-07-04 00:00:00
abstract：BACKGROUND:Anopheles culicifacies s.l. is one of the primary vectors of malaria in India responsible for the highest number of malaria cases. This vector is resistant to DDT in most parts of the country with indication of emerging resistance to pyrethroids. Since knockdown resistance (kdr) is known to confer cross-resi...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0946-7
更新日期：2015-06-18 00:00:00
abstract：BACKGROUND:The analysis of large mosquito samples is expensive and time-consuming, delaying the efficient timing of vector control measurements. Processing a fraction of a sample using a subsampling method can significantly reduce the processing effort. However, a comprehensive evaluation of the reliability of differen...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-019-3606-5
更新日期：2019-07-16 00:00:00
abstract：BACKGROUND:The identification of Trypanosoma cruzi and blood-meal sources in synanthropic triatomines is important to assess the potential risk of Chagas disease transmission. We identified T. cruzi infection and blood-meal sources of triatomines caught in and around houses in the state of Bahia, northeastern Brazil, a...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-019-3849-1
更新日期：2019-12-26 00:00:00
abstract：BACKGROUND:This laboratory study compared the efficacy of Bravecto™ (fluralaner), formulated as a chewable tablet, with the efficacy of Advocate® (imidacloprid/moxidectin), formulated for topical administration, against naturally acquired generalized demodicosis in dogs. METHODS:Sixteen dogs, all diagnosed with genera...
journal_title：Parasites & vectors
pub_type： 杂志文章,随机对照试验
doi：10.1186/s13071-015-0775-8
更新日期：2015-03-28 00:00:00
abstract：BACKGROUND:The role of endemic murid rodents as hosts of arthropod vectors of diseases of medical and veterinary significance is well established in the northern hemisphere. In contrast, endemic murids are comparatively understudied as vector hosts in Africa, particularly in South Africa. Considering the great rodent d...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-7-366
更新日期：2014-08-15 00:00:00
abstract：BACKGROUND:The use of phytochemicals is a promising solution in biological control against salmon louse (Lepeophtheirus salmonis). Glucosinolates belong to a diverse group of compounds used as protection against herbivores by plants in the family Brassicaceae, while in vertebrates, ingested glucosinolates exert health-...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1537-y
更新日期：2016-05-10 00:00:00
abstract：BACKGROUND:The merozoite of the zoonotic Plasmodium knowlesi invades human erythrocytes via the binding of its Duffy binding protein (PkDBPαII) to the Duffy antigen on the eythrocytes. The Duffy antigen has two immunologically distinct forms, Fya and Fyb. In this study, the erythrocyte-binding assay was used to quantit...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-3118-8
更新日期：2018-09-26 00:00:00
abstract：BACKGROUND:Leishmaniasis is a major parasitic disease worldwide, except in Australia and Antarctica, and it poses a significant public health problem. Due to the absence of safe and effective vaccines and drugs, researchers have begun an extensive search for new drugs. The aim of the current study was to investigate th...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04543-y
更新日期：2021-01-11 00:00:00
abstract：BACKGROUND:Schistosomiasis japonica remains a major public health concern in China. There are many interventions implemented to control the transmission of the disease. The purpose of the present study was to investigate the effects of an integrated control strategy for schistosomiasis control. METHODS:An integrated c...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-4-243
更新日期：2011-12-30 00:00:00
abstract：BACKGROUND:Cues that guide gravid Anopheles gambiae sensu lato to oviposition sites can be manipulated to create new strategies for monitoring and controlling malaria vectors. However, progress towards identifying such cues is slow in part due to the lack of appropriate tools for investigating long-range attraction to ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0916-0
更新日期：2015-06-03 00:00:00
abstract：BACKGROUND:Melophagus ovinus (Diptera: Hippoboscidae), a hematophagous ectoparasite, is mainly found in Europe, Northwestern Africa, and Asia. This wingless fly infests sheep, rabbits, and red foxes, and causes inflammation, wool loss and skin damage. Furthermore, this parasite has been shown to transmit diseases, and ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1885-7
更新日期：2016-11-25 00:00:00
abstract：BACKGROUND:West Nile virus (WNV) is a Flavivirus transmitted to vertebrate hosts by mosquitoes, maintained in nature through an enzootic bird-mosquito cycle. In Europe the virus became of major public health and veterinary concern in the 1990s. In Italy, WNV re-emerged in 2008, ten years after the previous outbreak and...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-1031-y
更新日期：2015-08-13 00:00:00
abstract：BACKGROUND:In many parts of Africa as in Benin, the main strategies of vector control are based on the scaling-up of Long Lasting Insecticide Treated Nets (LLITNs) and indoor residual spraying (IRS). The need to understand the biological implications of IRS in large scale and full coverage of LLITNs is paramount. It is...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-5-262
更新日期：2012-11-14 00:00:00
abstract：BACKGROUND:The relationship between the environment and infection of cattle with trematodes was studied at Arumeru District, Arusha Region, northern Tanzania. Randomly selected villages were grouped into three cattle management strata, (i) zero-grazing (ZZ) (ii) communal grazing without irrigation (ZC) and (iii) commun...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-7-107
更新日期：2014-03-20 00:00:00
