Abstract：
BACKGROUND:The cat flea (Ctenocephalides felis) is a blood-feeding ectoparasitic insect and particular nuisance pest of companion animals worldwide. Identification of genes that are differentially expressed in response to feeding is important for understanding flea biology and discovering targets for their control. METHODS:C. felis fleas were maintained and fed for 24 h using an artificial rearing system. The technique of suppression subtractive hybridization was employed to screen for mRNAs specifically expressed in fed fleas. RESULTS:We characterized nine distinct full-length flea transcripts that exhibited modulated or de novo expression during feeding. Among the predicted protein sequences were two serine proteases, a serine protease inhibitor, two mucin-like molecules, a DNA topoisomerase, an enzyme associated with GPI-mediated cell membrane attachment of proteins and a component of the insect innate immune response. CONCLUSIONS:Our results provide a molecular insight into the physiology of flea feeding. The protein products of the genes identified may play important roles during flea feeding in terms of blood meal digestion, cellular growth/repair and protection from feeding-associated stresses.
journal_name
Parasit Vectorsjournal_title
Parasites & vectorsauthors
Greene WK,Macnish MG,Rice KL,Thompson RCdoi
10.1186/s13071-015-0972-5subject
Has Abstractpub_date
2015-07-14 00:00:00pages
368issn
1756-3305pii
10.1186/s13071-015-0972-5journal_volume
8pub_type
杂志文章abstract：BACKGROUND:Triatoma dimidiata (Latreille) is a key vector complex of Trypanosoma cruzi, etiologic agent of Chagas disease, as it spans North, Central, and South America. Although morphological and genetic studies clearly indicate existence of at least five clades within the species, there has been no robust or systemat...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0678-8
更新日期：2015-02-06 00:00:00
abstract：BACKGROUND:African trypanosomosis is a disease of public health and economic importance that poses a major threat to the livelihoods of people living in the Maasai Steppe, where there is a significant interaction between people, livestock and wildlife. The vulnerability of the Maasai people to the disease is enhanced b...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2411-2
更新日期：2017-10-23 00:00:00
abstract：BACKGROUND:Taenia solium and Taenia saginata are zoonotic parasites of public health importance. Data on their occurrence in humans and animals in western Europe are incomplete and fragmented. In this study, we aimed to update the current knowledge on the epidemiology of these parasites in this region. METHODS:We cond...
journal_title：Parasites & vectors
pub_type： 杂志文章,评审
doi：10.1186/s13071-017-2280-8
更新日期：2017-07-21 00:00:00
abstract：BACKGROUND:There is a continuing need for novel approaches to tick control in dogs. One such approach lies in the ability of lotilaner (Credelio™), an isoxazoline with a rapid onset of action, to provide sustained efficacy against ticks. Two studies were undertaken to confirm lotilaner's efficacy, at the minimum dose r...
journal_title：Parasites & vectors
pub_type： 杂志文章,随机对照试验
doi：10.1186/s13071-017-2477-x
更新日期：2017-11-01 00:00:00
abstract：BACKGROUND:Sheep scab is caused by the ectoparasitic mite Psoroptes ovis which initiates a profound cutaneous inflammatory response, leading to the development of the skin lesions which are characteristic of the disease. Existing control strategies rely upon injectable endectocides and acaricidal dips but concerns over...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-5-30
更新日期：2012-02-08 00:00:00
abstract：BACKGROUND:Investigating malaria transmission dynamics is essential to inform policy decision making. Whether multiplicity of infection (MOI) dynamic from individual infections could be a reliable malaria metric in high transmission settings with marked variation in seasons of malaria transmission has been poorly asses...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04302-z
更新日期：2020-08-20 00:00:00
abstract：BACKGROUND:Toxoplasma gondii is an intracellular protozoan parasite that infects a wide variety of warm-blooded hosts, including humans. Limited information about T. gondii infection in bats is available in China. The objective of the present study was to determine prevalence and genetic characterization of T. gondii i...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-014-0558-7
更新日期：2014-12-03 00:00:00
abstract：BACKGROUND:To reveal the spatio-temporal distribution of malaria vectors in the national malaria surveillance sites from 2005 to 2010 and provide reference for the current National Malaria Elimination Programme (NMEP) in China. METHODS:A 6-year longitudinal surveillance on density of malaria vectors was carried out in...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0741-5
更新日期：2015-03-07 00:00:00
abstract：BACKGROUND:Phagocyte-derived extracellular traps (ETs) were recently demonstrated mainly in vertebrate hosts as an important effector mechanism against invading parasites. In the present study we aimed to characterize gastropod-derived invertebrate extracellular phagocyte trap (InEPT) formation in response to larval st...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1961-z
更新日期：2017-01-31 00:00:00
abstract：:Rickettsioses are among the oldest known infectious diseases. In spite of this, and of the extensive research carried out, many aspects of the biology and epidemiology of tick-borne rickettsiae are far from being completely understood. Their association with arthropod vectors, the importance of vertebrates as reservoi...
journal_title：Parasites & vectors
pub_type： 杂志文章,评审
doi：10.1186/s13071-018-2856-y
更新日期：2018-04-24 00:00:00
abstract：BACKGROUND:Lymphatic filariasis (LF) is a mosquito-borne parasitic disease and a major cause of disability worldwide. It is one of the neglected tropical diseases identified by the World Health Organization for elimination as a public health problem by 2020. Maps displaying disease distribution are helpful tools to ide...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-3097-9
更新日期：2018-09-17 00:00:00
abstract：BACKGROUND:Cryptosporidiosis is a gastrointestinal disease affecting many people worldwide. Disease incidence is often unknown and surveillance of human cryptosporidiosis is installed in only a handful of developed countries. A genetic marker that mirrors disease incidence is potentially a powerful tool for monitoring ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0921-3
更新日期：2015-06-06 00:00:00
abstract：BACKGROUND:Intestinal schistosomiasis due to Schistosoma mansoni was mapped in Cameroon in the 1990s and preventive chemotherapy launched since 2005. A situation analysis conducted in 2011 revealed an increase in schistosomiasis transmission, especially in the equatorial part of the country, despite the fact that Biomp...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-2763-2
更新日期：2018-03-13 00:00:00
abstract：BACKGROUND:Cues that guide gravid Anopheles gambiae sensu lato to oviposition sites can be manipulated to create new strategies for monitoring and controlling malaria vectors. However, progress towards identifying such cues is slow in part due to the lack of appropriate tools for investigating long-range attraction to ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0916-0
更新日期：2015-06-03 00:00:00
abstract：BACKGROUND:Certain municipalities in the Belo Horizonte Metropolitan Area (BHMA), Minas Gerais, Brazil, have the highest human visceral leishmaniasis (VL) mortality rates in the country and also demonstrate high canine seropositivity. In Brazil, the etiologic agent of VL is Leishmania (Leishmania) infantum. The aim of ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0837-y
更新日期：2015-04-15 00:00:00
abstract：BACKGROUND:The argasid tick Ornithodoros erraticus is the vector of African swine fever virus and of several Borrelia species that cause human relapsing fever in the Iberian Peninsula. The tick midgut is part of the ectoparasite-host interface and expresses proteins that are vital for the survival of the tick. Midgut p...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-1148-z
更新日期：2015-10-12 00:00:00
abstract：BACKGROUND:This laboratory study compared the efficacy of Bravecto™ (fluralaner), formulated as a chewable tablet, with the efficacy of Advocate® (imidacloprid/moxidectin), formulated for topical administration, against naturally acquired generalized demodicosis in dogs. METHODS:Sixteen dogs, all diagnosed with genera...
journal_title：Parasites & vectors
pub_type： 杂志文章,随机对照试验
doi：10.1186/s13071-015-0775-8
更新日期：2015-03-28 00:00:00
abstract：BACKGROUND:Schistosoma japonicum is one of the major causative agents of schistosomiasis. The pairing of males and females leads to female sexual maturation and maintains this mature state. However, the mechanisms by which pairing facilitates sexual maturation are yet to be investigated. METHODS:Parasites isolated fro...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-7-177
更新日期：2014-04-10 00:00:00
abstract：:Helminth infection may modulate the expression of Toll like receptors (TLR) in dendritic cells (DCs) and modify the responsiveness of DCs to TLR ligands. This may regulate aberrant intestinal inflammation in humans with helminthes and may thus help alleviate inflammation associated with human inflammatory bowel diseas...
journal_title：Parasites & vectors
pub_type： 杂志文章,评审
doi：10.1186/1756-3305-4-186
更新日期：2011-09-27 00:00:00
abstract：BACKGROUND:Understanding the dispersal dynamics of invasive mosquito species is fundamental to improve vector surveillance and to target control efforts. Aedes albopictus has been deemed a poor flyer as its range of active dispersal is generally assumed to be limited to a few hundred metres, while laboratory studies su...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-019-3837-5
更新日期：2019-12-12 00:00:00
abstract：BACKGROUND:Angiostrongylus cantonensis (A. cantonensis) infection can result in increased risk of eosinophilic meningitis. Accumulation of eosinophils and inflammation can result in the A. cantonensis infection playing an important role in brain tissue injury during this pathological process. However, underlying mechan...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0939-6
更新日期：2015-06-14 00:00:00
abstract：BACKGROUND:Blood parasites of the genus Haemoproteus Kruse, 1890 are cosmopolitan, might be responsible for mortality in non-adapted birds, and often kill blood-sucking insects. However, this group remains insufficiently investigated in the wild. This is particularly true for the parasites of leaf warblers of the Phyll...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-3109-9
更新日期：2018-10-04 00:00:00
abstract：BACKGROUND:The frequent outbreaks of human trichinellosis globally underscore the need to develop effective vaccine. We hypothesized that a novel vaccine could improve vaccine efficacy against Trichinella spiralis. METHODS:In this study, we developed virus-like particles (VLPs) containing the 53 KDa excretory/secretor...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1662-7
更新日期：2016-07-04 00:00:00
abstract：BACKGROUND:Neorickettsia are a group of intracellular α proteobacteria transmitted by digeneans (Platyhelminthes, Trematoda). These endobacteria can also infect vertebrate hosts of the helminths and cause serious diseases in animals and humans. Neorickettsia have been isolated from infected animals and maintained in ce...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2123-7
更新日期：2017-04-13 00:00:00
abstract：BACKGROUND:Parasitic infections may cause significant effects on behavior, learning, and memory of the host. In the brain of mice heavily infected with Angiostrongylus cantonensis, severe damage has been observed in the hippocampus. This component has been considered to have associations with spatial learning and memor...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04230-y
更新日期：2020-08-10 00:00:00
abstract：BACKGROUND:Schistosoma japonicum is a parasitic flatworm that causes human schistosomiasis. Secreted extracellular vesicles (EVs) play a key role in pathogen-host interfaces. Previous studies have shown that S. japonicum adult worms can release microRNA (miRNA)-containing EVs, which can transfer their cargo to mammalia...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1845-2
更新日期：2016-11-08 00:00:00
abstract：BACKGROUND:Because agriculture and offshore oil extraction are significant economic activities in the southern Gulf of Mexico, high concentrations of nutrients and hydrocarbons are expected. As parasite communities are sensitive to environmental impacts, these contaminants should have an effect on metrics such as speci...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-014-0541-3
更新日期：2014-11-27 00:00:00
abstract：BACKGROUND:Anopheles barbirostris sensu lato belongs to the Barbirostris subgroup of the subgenus Anopheles that is distributed in Southeast Asia. Different molecular forms have been identified based on the rDNA-ITS2 and mtDNA-COI sequences. Anopheles barbirostris occurs in China. The species status was uncertain due t...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-014-0592-5
更新日期：2014-12-16 00:00:00
abstract：BACKGROUND:Bioclimatic variables play an integral part in the life-cycle of Ctenocephalides felis, the most common flea found on companion animals. It is essential that we understand the effects of climate on C. felis distribution as fleas are a major veterinary and public health concern. This study investigated the cu...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-019-3399-6
更新日期：2019-03-22 00:00:00
abstract：:The control of insects of medical importance, such as Aedes aegypti and Aedes albopictus are still the only effective way to prevent the transmission of diseases, such as dengue, chikungunya and Zika. Their control is performed mainly using chemical products; however, they often have low specificity to non-target orga...
journal_title：Parasites & vectors
pub_type： 杂志文章,评审
doi：10.1186/s13071-020-04236-6
更新日期：2020-07-29 00:00:00
