Implications of childhood obesity for adult health: findings from thousand families cohort study.

abstract：OBJECTIVE:To examine the absolute risks or benefits on cancer associated with oral contraception, using incident data. DESIGN:Inception cohort study. SETTING:Royal College of General Practitioners' oral contraception study. PARTICIPANTS:Directly standardised data from the Royal College of General Practitioners' oral...

journal_title：BMJ (Clinical research ed.)

authors： Hannaford PC,Selvaraj S,Elliott AM,Angus V,Iversen L,Lee AJ

更新日期：2007-09-29 00:00:00

abstract：OBJECTIVE:To study the processes involved in and impact of mergers between NHS trusts, including the effect on management costs. DESIGN:Cross sectional study involving in depth interviews and documentary analysis; case study to compare savings in management costs between case trusts and control trusts. SETTING:Nine t...

journal_title：BMJ (Clinical research ed.)

authors： Fulop N,Protopsaltis G,Hutchings A,King A,Allen P,Normand C,Walters R

更新日期：2002-08-03 00:00:00

abstract：OBJECTIVES:To investigate the association between four sociodemographic measures (unemployment, overcrowding, low social class, and the proportion of migrants from areas of high prevalence of tuberculosis) and average level and rate of change of notification rates for tuberculosis. DESIGN:Ecological analysis of both t...

journal_title：BMJ (Clinical research ed.)

authors： Mangtani P,Jolley DJ,Watson JM,Rodrigues LC

更新日期：1995-04-15 00:00:00

abstract：OBJECTIVE:To assess the effect of size at birth, maternal nutrition, and body mass index on blood pressure in late adolescence. DESIGN:Population based analysis of birth weight corrected for gestational age, mother's weight before pregnancy and weight gain in pregnancy, obtained from the Jerusalem perinatal study, and...

journal_title：BMJ (Clinical research ed.)

authors： Laor A,Stevenson DK,Shemer J,Gale R,Seidman DS

更新日期：1997-08-23 00:00:00

abstract：:Objective To improve the selection of patients with acute ischaemic stroke for intra-arterial treatment using a clinical decision tool to predict individual treatment benefit.Design Multivariable regression modelling with data from two randomised controlled clinical trials.Setting 16 hospitals in the Netherlands (deri...

journal_title：BMJ (Clinical research ed.)

authors： Venema E,Mulder MJHL,Roozenbeek B,Broderick JP,Yeatts SD,Khatri P,Berkhemer OA,Emmer BJ,Roos YBWEM,Majoie CBLM,van Oostenbrugge RJ,van Zwam WH,van der Lugt A,Steyerberg EW,Dippel DWJ,Lingsma HF

更新日期：2017-05-03 00:00:00

abstract：OBJECTIVE:To assess whether a strategy of endovascular repair (if aortic morphology is suitable, open repair if not) versus open repair reduces early mortality for patients with suspected ruptured abdominal aortic aneurysm. DESIGN:Randomised controlled trial. SETTING:30 vascular centres (29 UK, 1 Canadian), 2009-13. ...

journal_title：BMJ (Clinical research ed.)

authors： IMPROVE Trial Investigators.,Powell JT,Sweeting MJ,Thompson MM,Ashleigh R,Bell R,Gomes M,Greenhalgh RM,Grieve R,Heatley F,Hinchliffe RJ,Thompson SG,Ulug P

更新日期：2014-01-13 00:00:00

abstract：OBJECTIVES:To explore why cancer patients do not want or seek information about their condition beyond that volunteered by their physicians at times during their illness. DESIGN:Qualitative study based on in-depth interviews. SETTING:Outpatient oncology clinics at a London cancer centre. PARTICIPANTS:17 patients wit...

journal_title：BMJ (Clinical research ed.)

authors： Leydon GM,Boulton M,Moynihan C,Jones A,Mossman J,Boudioni M,McPherson K

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:To examine the effectiveness of post-diagnosis dementia treatment and coordination of care by memory clinics compared with general practitioners. DESIGN:Multicentre randomised controlled trial. SETTING:Nine memory clinics and 159 general practitioners in the Netherlands. PARTICIPANTS:175 patients with a ne...

journal_title：BMJ (Clinical research ed.)

authors： Meeuwsen EJ,Melis RJ,Van Der Aa GC,Golüke-Willemse GA,De Leest BJ,Van Raak FH,Schölzel-Dorenbos CJ,Verheijen DC,Verhey FR,Visser MC,Wolfs CA,Adang EM,Olde Rikkert MG

更新日期：2012-05-15 00:00:00

abstract：OBJECTIVE:To determine the most effective tocolytic agent at delaying delivery. DESIGN:Systematic review and network meta-analysis. DATA SOURCES:Cochrane Central Register of Controlled Trials, Medline, Medline In-Process, Embase, and CINAHL up to 17 February 2012. STUDY SELECTION:Randomised controlled trials of toco...

journal_title：BMJ (Clinical research ed.)

authors： Haas DM,Caldwell DM,Kirkpatrick P,McIntosh JJ,Welton NJ

更新日期：2012-10-09 00:00:00

abstract：OBJECTIVES:To investigate trends in the incidence of acute pancreatitis resulting in admission to hospital, and mortality after admission, from 1963 to 1998. DESIGN:Analysis of hospital inpatient statistics for acute pancreatitis, linked to data from death certificates. SETTING:Southern England. SUBJECTS:5312 people...

journal_title：BMJ (Clinical research ed.)

authors： Goldacre MJ,Roberts SE

更新日期：2004-06-19 00:00:00

abstract：OBJECTIVES:To determine the accuracy of diagnoses of schizophrenia and non-affective psychosis entered by general practitioners on a computer system. To compare recording of clinical events on computer with written records. DESIGN:Examination of case notes of all patients with a computer diagnosis of psychosis. Search...

journal_title：BMJ (Clinical research ed.)

authors： Nazareth I,King M,Haines A,Rangel L,Myers S

更新日期：1993-07-03 00:00:00

abstract：OBJECTIVES:To assess incidence of and mortality from cancer in hypertensive patients taking atenolol, comparing the findings with two control populations and with hypertensive patients taking other drugs. DESIGN:Retrospective analysis of patients first seen in the Glasgow Blood Pressure Clinic between 1972 and 1990. P...

journal_title：BMJ (Clinical research ed.)

authors： Hole DJ,Hawthorne VM,Isles CG,McGhee SM,Robertson JW,Gillis CR,Wapshaw JA,Lever AF

更新日期：1993-03-06 00:00:00

abstract：OBJECTIVE:To investigate the effect of overweight on premature mortality and work disability in young and middle aged Finns. DESIGN:Prospective cohort study based on data collected in the multiphasic health examinations by the Social Insurance Institution of Finland from 1966 to 1972 and follow up until 1982. SETTING...

journal_title：BMJ (Clinical research ed.)

authors： Rissanen A,Heliövaara M,Knekt P,Reunanen A,Aromaa A,Maatela J

更新日期：1990-10-13 00:00:00

abstract：OBJECTIVE:To assess the potential effects of primary prevention with anticoagulants or aspirin in atrial fibrillation on Swedish population. DESIGN:Analysis of cost effectiveness based on the following assumptions: about 83,000 people have atrial fibrillation in Sweden, of whom 22,000 would be potential candidates for...

journal_title：BMJ (Clinical research ed.)

authors： Gustafsson C,Asplund K,Britton M,Norrving B,Olsson B,Marké LA

更新日期：1992-12-12 00:00:00

abstract：:Hepatorenal syndrome (HRS), the extreme manifestation of renal impairment in patients with cirrhosis, is characterized by reduction in renal blood flow and glomerular filtration rate. Hepatorenal syndrome is diagnosed when kidney function is reduced but evidence of intrinsic kidney disease, such as hematuria, proteinu...

journal_title：BMJ (Clinical research ed.)

authors： Simonetto DA,Gines P,Kamath PS

更新日期：2020-09-14 00:00:00

abstract：OBJECTIVE:To examine whether, according to the conclusions of a 2000 systematic review with meta-analysis on interventions to prevent pain from propofol injection that provided a research agenda to guide further research on the topic, subsequently published trials were more often optimally blinded, reported on children...

journal_title：BMJ (Clinical research ed.)

authors： Habre C,Tramèr MR,Pöpping DM,Elia N

更新日期：2014-08-26 00:00:00

abstract：OBJECTIVE:To evaluate the performance of a rapid test for chlamydia with first void male urine samples as a potential tool for diagnosis and screening of chlamydial infection in men. DESIGN:Evaluation of test performance in prospective cohort study. Settings A young people's sexual health centre (site 1) and a genitou...

journal_title：BMJ (Clinical research ed.)

authors： Nadala EC,Goh BT,Magbanua JP,Barber P,Swain A,Alexander S,Laitila V,Michel CE,Mahilum-Tapay L,Ushiro-Lumb I,Ison C,Lee HH

更新日期：2009-07-28 00:00:00

abstract：OBJECTIVE:To assess the association between genitourinary infections in the month before conception to the end of the first trimesterand gastroschisis. DESIGN:Case-control study with self reported infections from a computer assisted telephone interview. SETTING:National birth defects prevention study, a multisite, po...

journal_title：BMJ (Clinical research ed.)

authors： Feldkamp ML,Reefhuis J,Kucik J,Krikov S,Wilson A,Moore CA,Carey JC,Botto LD

更新日期：2008-06-21 00:00:00

abstract：OBJECTIVES:To investigate the effect of milk supplementation on total body bone mineral acquisition in adolescent girls. DESIGN:18 month, open randomised intervention trial. SUBJECTS:82 white girls aged 12.2 (SD 0.3) years, recruited from four secondary schools in Sheffield. INTERVENTION:568 ml (one pint) of whole o...

journal_title：BMJ (Clinical research ed.)

authors： Cadogan J,Eastell R,Jones N,Barker ME

更新日期：1997-11-15 00:00:00

abstract：OBJECTIVES:To observe one general practice's attempt to reduce prescribing costs on becoming third wave fundholders through the introduction of a generic formulary applied to all new and repeat prescribing. To assess the impact on patients and prescribing patterns. DESIGN:An observational study using interviews with p...

journal_title：BMJ (Clinical research ed.)

authors： Dowell JS,Snadden D,Dunbar JA

更新日期：1995-02-25 00:00:00

abstract：OBJECTIVE:To describe the characteristics of patients using non-orthodox health care and their pattern of use of conventional health care with respect to a particular problem. DESIGN:Postal survey of all 2152 practitioners of acupuncture, chiropractic, homeopathy, naturopathy, and osteopathy identified from 11 nationa...

journal_title：BMJ (Clinical research ed.)

authors： Thomas KJ,Carr J,Westlake L,Williams BT

更新日期：1991-01-26 00:00:00

abstract：:The International AIDS Vaccine Initiative, based in New York, US, was established in 1996 to develop a safe and affordable AIDS vaccine. It is funded by a number of large foundations and charities, the British government, and the World Bank. The Initiative's first 2 large projects, 2 research programs into a vaccine...

journal_title：BMJ (Clinical research ed.)

authors： Matthews H

更新日期：1998-12-05 00:00:00

abstract：OBJECTIVE:To appraise a new method of prenatal screening for Down's syndrome based on maternal serum concentrations of alpha fetoprotein, unconjugated oestriol, and human chorionic gonadotrophin combined with maternal age--the "triple test." DESIGN:Examination of the cost effectiveness of the triple test relative to s...

journal_title：BMJ (Clinical research ed.)

authors： Sheldon TA,Simpson J

更新日期：1991-05-11 00:00:00

abstract：OBJECTIVE:To determine whether the link suggested between growth in utero and during infancy and death from cardiovascular disease in men is also present in women. DESIGN:Follow up study of women and men whose birth weight and weight at 1 year of age had been recorded. SETTING:Hertfordshire, England. SUBJECTS:5585 w...

journal_title：BMJ (Clinical research ed.)

authors： Osmond C,Barker DJ,Winter PD,Fall CH,Simmonds SJ

更新日期：1993-12-11 00:00:00

abstract：OBJECTIVE:To review and critically appraise published and preprint reports of prediction models for diagnosing coronavirus disease 2019 (covid-19) in patients with suspected infection, for prognosis of patients with covid-19, and for detecting people in the general population at increased risk of becoming infected with...

journal_title：BMJ (Clinical research ed.)

authors： Wynants L,Van Calster B,Collins GS,Riley RD,Heinze G,Schuit E,Bonten MMJ,Damen JAA,Debray TPA,De Vos M,Dhiman P,Haller MC,Harhay MO,Henckaerts L,Kreuzberger N,Lohman A,Luijken K,Ma J,Andaur CL,Reitsma JB,Sergeant

更新日期：2020-04-07 00:00:00

abstract：OBJECTIVE:Rapid diagnostic tests for malaria seem cost effective in standard analyses, but these do not take account of clinicians' response to test results. This study tested the impact of clinicians' response to rapid diagnostic test or microscopy results on the costs and benefits of testing at different levels of ma...

journal_title：BMJ (Clinical research ed.)

authors： Lubell Y,Reyburn H,Mbakilwa H,Mwangi R,Chonya S,Whitty CJ,Mills A

更新日期：2008-01-26 00:00:00

abstract：OBJECTIVES:To examine the association of plasma caffeine concentrations during pregnancy with fetal growth and to compare this with relations with reported caffeine intake. DESIGN:Prospective population based study. SETTING:District general hospital, inner London. SUBJECTS:Women booking for delivery between 1982 and...

journal_title：BMJ (Clinical research ed.)

authors： Cook DG,Peacock JL,Feyerabend C,Carey IM,Jarvis MJ,Anderson HR,Bland JM

更新日期：1996-11-30 00:00:00

abstract：OBJECTIVE:To determine the effect of home blood pressure monitoring on blood pressure levels and proportion of people with essential hypertension achieving targets. DESIGN:Meta-analysis of 18 randomised controlled trials. PARTICIPANTS:1359 people with essential hypertension allocated to home blood pressure monitoring...

journal_title：BMJ (Clinical research ed.)

authors： Cappuccio FP,Kerry SM,Forbes L,Donald A

更新日期：2004-07-17 00:00:00

abstract：:Stroke is the leading cause of long term disability in developed countries and one of the top causes of mortality worldwide. The past decade has seen substantial advances in the diagnostic and treatment options available to minimize the impact of acute ischemic stroke. The key first step in stroke care is early identi...

journal_title：BMJ (Clinical research ed.)

authors： Phipps MS,Cronin CA

更新日期：2020-02-13 00:00:00

abstract：OBJECTIVES:To determine the clinical and radiological features of severe acute respiratory syndrome (SARS) and to evaluate the accuracy of the World Health Organization's guidelines on defining cases of SARS. DESIGN:Prospective observational study. SETTING:A newly set up SARS screening clinic in the emergency departm...

journal_title：BMJ (Clinical research ed.)

authors： Rainer TH,Cameron PA,Smit D,Ong KL,Hung AN,Nin DC,Ahuja AT,Si LC,Sung JJ

更新日期：2003-06-21 00:00:00