Cancer risk among users of oral contraceptives: cohort data from the Royal College of General Practitioner's oral contraception study.

abstract：OBJECTIVE:To determine the relative contribution of decline in bone density to the increase in risk of hip fracture with age in men and women. DESIGN:Incidence data of hip fracture from the general population were combined with the bone density distribution in a sample from the same population and with a risk estimate...

journal_title：BMJ (Clinical research ed.)

authors： De Laet CE,van Hout BA,Burger H,Hofman A,Pols HA

更新日期：1997-07-26 00:00:00

abstract：OBJECTIVE:To obtain data on sexual contact between doctors and their patients. DESIGN:Anonymous questionnaire with 17 items sent to all working gynaecologists (n = 595) and all ear, nose, and throat specialists (n = 380) in the Netherlands. RESULTS:Response rate was 74%; a total 64 doctors gave a reason for not compl...

journal_title：BMJ (Clinical research ed.)

authors： Wilbers D,Veenstra G,van de Wiel HB,Weijmar Schultz WC

更新日期：1992-06-13 00:00:00

abstract：OBJECTIVE:Although the Polypill concept (proposed in 2003) is promising in terms of benefits for cardiovascular risk management, the potential costs and adverse effects are its main pitfalls. The objective of this study was to identify a tastier and safer alternative to the Polypill: the Polymeal. METHODS:Data on the ...

journal_title：BMJ (Clinical research ed.)

authors： Franco OH,Bonneux L,de Laet C,Peeters A,Steyerberg EW,Mackenbach JP

更新日期：2004-12-18 00:00:00

abstract：:Planning future policy for medicines poses difficult problems. The main players in the drug business have their own views as to how the world around them functions and how the future of medicines should be shaped. In this paper we show how a scenario analysis can provide a powerful teaching device to readjust peoples'...

journal_title：BMJ (Clinical research ed.)

authors： Leufkens H,Haaijer-Ruskamp F,Bakker A,Dukes G

更新日期：1994-10-29 00:00:00

abstract：OBJECTIVE:To explore geographical and sociodemographic factors associated with variation in equity in access to total hip and knee replacement surgery. DESIGN:Combining small area estimates of need and provision to explore equity in access to care. SETTING:English census wards. SUBJECTS:Patients throughout England w...

journal_title：BMJ (Clinical research ed.)

authors： Judge A,Welton NJ,Sandhu J,Ben-Shlomo Y

更新日期：2010-08-11 00:00:00

abstract：OBJECTIVE:To cost the relation between socioeconomic status and various measures of primary care workload and assess the adequacy of current "deprivation" payments in relation to actual costings for patients living in qualifying areas. DESIGN:Retrospective data on primary care were collected over a 4.5 year period fro...

journal_title：BMJ (Clinical research ed.)

authors： Worrall A,Rea JN,Ben-Shlomo Y

更新日期：1997-01-04 00:00:00

abstract：OBJECTIVES:To assess heat related mortalities in relation to climate within Europe. DESIGN:Observational population study. SETTING:North Finland, south Finland, Baden-Württemberg, Netherlands, London, north Italy, and Athens. SUBJECTS:People aged 65-74. MAIN OUTCOME MEASURES:Mortalities at temperatures above, below...

journal_title：BMJ (Clinical research ed.)

authors： Keatinge WR,Donaldson GC,Cordioli E,Martinelli M,Kunst AE,Mackenbach JP,Nayha S,Vuori I

更新日期：2000-09-16 00:00:00

abstract：OBJECTIVE:To assess the extent to which the prevailing model of smoking cessation (that smokers typically prepare their attempts to stop smoking in advance and that doing so increases their chances of success) is correct. DESIGN:Cross sectional household survey. SETTING:England. PARTICIPANTS:918 smokers who reported...

journal_title：BMJ (Clinical research ed.)

authors： West R,Sohal T

更新日期：2006-02-25 00:00:00

abstract：OBJECTIVE:To estimate the costs of diagnosis and treatment of diabetes in Tanzania. DESIGN:Costs estimated from the reported and recorded experience of patients with newly presenting diabetes in 1989-90 and of diabetic patients first seen in 1981-2. SETTING:Muhimbili Medical Centre, Dar es Salaam. SUBJECTS:464 patie...

journal_title：BMJ (Clinical research ed.)

authors： Chale SS,Swai AB,Mujinja PG,McLarty DG

更新日期：1992-05-09 00:00:00

abstract：OBJECTIVES:To report on the country of training and ethnicity of consultants in different specialties in the NHS, on trends in intake to UK medical schools by ethnicity, and on the specialty choices made by UK medical graduates in different ethnic groups. DESIGN:Analysis of official databases of consultants and of stu...

journal_title：BMJ (Clinical research ed.)

authors： Goldacre MJ,Davidson JM,Lambert TW

更新日期：2004-09-11 00:00:00

abstract：:Objective To characterize the prospective controlled clinical studies for all novel drugs that were initially approved by the Food and Drug Administration on the basis of limited evidence.Design Systematic review.Data sources Drugs@FDA database and PubMed.Study inclusion All prospective controlled clinical studies pub...

journal_title：BMJ (Clinical research ed.)

authors： Pease AM,Krumholz HM,Downing NS,Aminawung JA,Shah ND,Ross JS

更新日期：2017-05-03 00:00:00

abstract：OBJECTIVE:To assess general practitioners' decisions to request lumbar spine radiographs according to the guidelines of the Royal College of Radiologists. DESIGN:Prospective questionnaire survey of outpatients attending for lumbar spine radiography. SETTING:London community hospital. SUBJECTS:100 consecutive adult o...

journal_title：BMJ (Clinical research ed.)

authors： Halpin SF,Yeoman L,Dundas DD

更新日期：1991-10-05 00:00:00

abstract：BACKGROUND:Twenty-four hour ambulatory blood pressure thresholds have been defined for the diagnosis of mild hypertension but not for its treatment or for other blood pressure thresholds used in the diagnosis of moderate to severe hypertension. We aimed to derive age and sex related ambulatory blood pressure equivalent...

journal_title：BMJ (Clinical research ed.)

authors： Head GA,Mihailidou AS,Duggan KA,Beilin LJ,Berry N,Brown MA,Bune AJ,Cowley D,Chalmers JP,Howe PR,Hodgson J,Ludbrook J,Mangoni AA,McGrath BP,Nelson MR,Sharman JE,Stowasser M,Ambulatory Blood Pressure Working Group of the

更新日期：2010-04-14 00:00:00

abstract：:Prediction models are developed to aid health care providers in estimating the probability or risk that a specific disease or condition is present (diagnostic models) or that a specific event will occur in the future (prognostic models), to inform their decision making. However, the overwhelming evidence shows that th...

journal_title：BMJ (Clinical research ed.)

authors： Collins GS,Reitsma JB,Altman DG,Moons KG

更新日期：2015-01-07 00:00:00

abstract：OBJECTIVE:To determine the long term effects of antibiotic treatment for acute otitis media in young children. DESIGN:Prospective three year follow-up study within the framework of a primary care based, double blind, randomised, placebo controlled trial. SETTING:53 general practices in the Netherlands. PARTICIPANTS:...

journal_title：BMJ (Clinical research ed.)

authors： Bezáková N,Damoiseaux RA,Hoes AW,Schilder AG,Rovers MM

更新日期：2009-06-30 00:00:00

abstract：OBJECTIVE:To determine whether a relation between urinary retention and temporal rhythms exists. DESIGN:Retrospective analysis of patients presenting over three years. SETTING:Urology departments in two hospitals. PATIENTS:815 Patients presenting as emergency admissions with urinary retention and requiring immediate...

journal_title：BMJ (Clinical research ed.)

authors： Payne SR,Deardon DJ,Abercrombie GF,Carlson GL

更新日期：1989-12-23 00:00:00

abstract：OBJECTIVES:To determine whether measurement of total cholesterol concentration is sufficient to identify most patients at lipoprotein mediated risk of coronary heart disease without measurement of triglyceride and high density lipoprotein (HDL) cholesterol concentrations. DESIGN:Cross sectional screening programme. S...

journal_title：BMJ (Clinical research ed.)

authors： Neil HA,Mant D,Jones L,Morgan B,Mann JI

更新日期：1990-09-22 00:00:00

abstract：OBJECTIVE:To assess whether sleep apnoea syndrome is an independent risk factor for hypertension. DESIGN:Population study. SETTING:Sleep clinic in Toronto. PARTICIPANTS:2,677 adults, aged 20-85 years, referred to the sleep clinic with suspected sleep apnoea syndrome. OUTCOME MEASURES:Medical history, demographic da...

journal_title：BMJ (Clinical research ed.)

authors： Lavie P,Herer P,Hoffstein V

更新日期：2000-02-19 00:00:00

abstract：OBJECTIVE:To examine the protective efficacy of measles vaccination in infants in a low income country before 9 months of age. DESIGN:Randomised clinical trial. PARTICIPANTS:1333 infants aged 4.5 months: 441 in treatment group and 892 in control group. SETTING:Urban area in Guinea-Bissau. INTERVENTION:Measles vacci...

journal_title：BMJ (Clinical research ed.)

authors： Martins CL,Garly ML,Balé C,Rodrigues A,Ravn H,Whittle HC,Lisse IM,Aaby P

更新日期：2008-07-24 00:00:00

abstract：OBJECTIVE:To systematically determine the impact of growth hormone therapy on adult height of children with idiopathic short stature. DESIGN:Systematic review. DATA SOURCES:Cochrane Central Register of Controlled Trials, Medline, and the bibliographic references from retrieved articles of randomised and non-randomise...

journal_title：BMJ (Clinical research ed.)

authors： Deodati A,Cianfarani S

更新日期：2011-03-11 00:00:00

abstract：OBJECTIVES:To support already established epidemiological links between inmates of Glenochil prison positive for HIV infection by using molecular techniques and thus provide evidence of the extent of acquisition during a recent outbreak of the disease resulting from needle sharing. To identify possible sources of the o...

journal_title：BMJ (Clinical research ed.)

authors： Yirrell DL,Robertson P,Goldberg DJ,McMenamin J,Cameron S,Leigh Brown AJ

更新日期：1997-05-17 00:00:00

abstract：:An association between vasectomy and the development of testicular tumors, and the importance of testicular examinations both before and after a vasectomy is discussed. Patients diagnosed with testicular tumors within the last ten years were examined at Bangour General Hospital in Scotland. From 1977-87, 37 patients...

journal_title：BMJ (Clinical research ed.)

authors： Cale AR,Farouk M,Prescott RJ,Wallace IW

更新日期：1990-02-10 00:00:00

abstract：OBJECTIVE:To assess the association between genotype at the insertion or deletion polymorphism of the angiotensin converting enzyme gene and risk of coronary restenosis after percutaneous coronary intervention. DESIGN:Meta-analysis of studies before July 2001 that reported on these genotypes and risk of coronary reste...

journal_title：BMJ (Clinical research ed.)

authors： Bonnici F,Keavney B,Collins R,Danesh J

更新日期：2002-09-07 00:00:00

abstract：OBJECTIVE:To describe mortality by suicide and other causes of death in a group of patients who attempted suicide, and to identify predictive factors. DESIGN:10 year follow up study based on records of suicide attempters in 1980. SETTING:Poisoning treatment centre at a general hospital. SUBJECTS:974 patients aged 15...

journal_title：BMJ (Clinical research ed.)

authors： Nordentoft M,Breum L,Munck LK,Nordestgaard AG,Hunding A,Laursen Bjaeldager PA

更新日期：1993-06-19 00:00:00

abstract：:In prospective studies, the prevalence of undiagnosed subclinical hypothyroidism in pregnant women ranges from 3% to 15%. Subclinical hypothyroidism is associated with multiple adverse outcomes in the mother and fetus, including spontaneous abortion, pre-eclampsia, gestational hypertension, gestational diabetes, prete...

journal_title：BMJ (Clinical research ed.)

authors： Negro R,Stagnaro-Green A

更新日期：2014-10-06 00:00:00

abstract：:The studyEveritt H, Landau G, Little P. Therapist telephone-delivered CBT and web-based CBT compared with treatment as usual in refractory irritable bowel syndrome: the ACTIB three-arm RCT. Health Technol Assess 2019;23:1-154.This project was funded by the NIHR Health Technology Assessment Programme (project number 11...

journal_title：BMJ (Clinical research ed.)

authors： Cook R,Davidson P,Martin R,NIHR Dissemination Centre.

更新日期：2019-11-04 00:00:00

abstract：OBJECTIVE:To determine the effectiveness of interventions designed to improve outcomes in patients with multimorbidity in primary care and community settings. DESIGN:Systematic review. DATA SOURCES:Medline, Embase, CINAHL, CAB Health, Cochrane central register of controlled trials, the database of abstracts of review...

journal_title：BMJ (Clinical research ed.)

authors： Smith SM,Soubhi H,Fortin M,Hudon C,O'Dowd T

更新日期：2012-09-03 00:00:00

abstract：OBJECTIVE:To investigate the effect of immediate feedback from a point of care test for salivary nicotine metabolites in promoting smoking cessation and reduction in tobacco use. DESIGN:Prospective, operator blinded, randomised controlled trial. SETTING:General dental practice, London. PARTICIPANTS:100 adult smokers...

journal_title：BMJ (Clinical research ed.)

authors： Barnfather KD,Cope GF,Chapple IL

更新日期：2005-10-29 00:00:00

abstract：OBJECTIVES:To investigate the feasibility of obtaining signed consent for submission of patient identifiable data to a national clinical audit database and to identify factors influencing the consent process and its success. DESIGN:Feasibility study. SETTING:Seven paediatric intensive care units in England. PARTICIP...

journal_title：BMJ (Clinical research ed.)

authors： McKinney PA,Jones S,Parslow R,Davey N,Darowski M,Chaudhry B,Stack C,Parry G,Draper ES,PICANet Consent Study Group.

更新日期：2005-04-16 00:00:00

abstract：:Molecular techniques have revolutionised our knowledge of cell and tissue function in both health and disease. We already have new and powerful treatments based on an understanding of communication between cells by messenger molecules called cytokines. Furthermore, there is great therapeutic promise in defining molecu...

journal_title：BMJ (Clinical research ed.)

authors： Savill J

更新日期：1997-01-18 00:00:00