Abstract：
BACKGROUND:Hypertensive disorders of pregnancy are the most common causes of adverse maternal & perinatal outcomes. Such investigations in resource limited settings would help to have great design strategies in preventing maternal and perinatal morbidity and mortality. AIM:To determine management outcome and factor associated with pregnancy related hypertensive disorder in Mettu Karl Referral Hospital, Mettu, Ethiopia. METHOD:A retrospective study deign was conducted at Mettu Karl Referral Hospital from 1st January 2010 to December 1st 2013 by reviewing medical records and logbooks. Descriptive, binary and multiple logistic regression analysis were used. A 95% CI and P- value of < 0.05 were considered statistically significant. RESULT:The magnitude of pregnancy related hypertensive disorder was 2.4%. Majority 82.6% of the mothers were in the age range between 18 to 34 year with a mean age and standard deviation (SD) of 24.4 (SD ± 5.12). Sever preeclampsia was the most prevalent diagnosis made to 35.5% of the mother, followed by 19% cases of eclampsia and 12.4% of HELLP. Fetal management outcomes indicates 120.37 perinatal mortality per 1000 deliveries and a stillbirth rate of 10.2%, low birth weight of 30.5%, and low APGAR score of 18.5%, abortion 10.7% and preterm delivery 31.4%. CONCLUSION:In this study severe preeclampsia is the most common of all pregnancy related hypertension disorders followed by Eclampsia. Fetal complications like low Apgar score and preterm deliveries were statistically significant and associated with fetal management outcomes.
journal_name
J Ovarian Resjournal_title
Journal of ovarian researchauthors
Seyom E,Abera M,Tesfaye M,Fentahun Ndoi
10.1186/s13048-015-0135-5subject
Has Abstractpub_date
2015-03-15 00:00:00pages
10issn
1757-2215pii
s13048-015-0135-5journal_volume
8pub_type
杂志文章abstract：:Both estrogens and androgens are involved in the development and normal functioning of the ovaries. It is also known that ovarian function is regulated by diet. The goal of this study was to estimate the expression of sex hormone receptors in ovaries of mice that were on a 9-month caloric restriction (alternate-day fe...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-015-0185-8
更新日期：2015-08-13 00:00:00
abstract：BACKGROUND:Mucinous carcinomas from different organs are morphologically similar and might share similarities at the molecular and biochemical levels that may illuminate their pathogenesis and influence management. The factors involved in the pathogenesis of mucinous carcinomas remain unknown; which is likely one contr...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-015-0169-8
更新日期：2015-06-17 00:00:00
abstract：:We have earlier reported the presence of very small embryonic-like stem cells (VSELs) in adult mouse uterus along with slightly bigger progenitors termed endometrial stem cells (EnSCs) and their regulation by ovarian hormones thus demonstrating a crucial role played by them during proliferation, differentiation and re...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-017-0324-5
更新日期：2017-04-24 00:00:00
abstract：OBJECTIVE:Recently, 14-3-3 zeta protein was identified as a potential serum biomarker of epithelial ovarian cancer (EOC). The goal of this study was to investigate the clinical potential of 14-3-3 zeta protein for monitoring EOC progression compared with CA-125 and HE4. DESIGN:Prospective follow-up study. SETTING:Uni...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-6-79
更新日期：2013-11-15 00:00:00
abstract：:Mixed germ cell tumours of the ovary are malignant neoplasms of the ovary comprising of two or more types of germ cell components. Most of the malignant mixed germ cell tumours consists of dysgerminoma accompanied by endodermal sinus tumours, immature teratoma or choriocarcinoma. There are only few case reports of mix...
journal_title：Journal of ovarian research
pub_type： 杂志文章,评审
doi：10.1186/s13048-014-0091-5
更新日期：2014-11-04 00:00:00
abstract：BACKGROUND:Despite advances in surgical aggressiveness and conventional chemotherapy, ovarian cancer remains the most lethal cause of gynecologic cancer mortality; consequently there is a need for new therapeutic agents and innovative treatment paradigms for the treatment of ovarian cancer. Several studies have demonst...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-016-0282-3
更新日期：2016-10-27 00:00:00
abstract：BACKGROUND:This study evaluated the influence of menstrual cycle length, menstrual cycle variability and predicted luteal phase length on the success of vitrified-warmed blastocyst transfer in natural menstrual cycle using progesterone for luteal phase supplementation. METHODS:Consecutive women undergoing vitrified-wa...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-018-0436-6
更新日期：2018-08-02 00:00:00
abstract：:Currently, the world is in the seventh month of the COVID-19 pandemic. Globally, infections with novel SARS-CoV-2 virus are continuously rising with mounting numbers of deaths. International and local public health responses, almost in synchrony, imposed restrictions to minimize spread of the virus, overload of health...
journal_title：Journal of ovarian research
pub_type： 杂志文章,评审
doi：10.1186/s13048-020-00737-1
更新日期：2020-11-27 00:00:00
abstract：BACKGROUND:This study aimed to identify the clinical and pathological characteristics and the possible prognostic factors for Chinese patients with early-stage ovarian endometrioid carcinoma. METHODS:The present study reviewed the medical records of patients who received initial treatment and a postoperative pathologi...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-017-0361-0
更新日期：2017-09-18 00:00:00
abstract：BACKGROUND:We aimed to examine the expression of miR-1307 in chemosensitive and chemoresistant epithelial ovarian cancer tissues and cell lines and to analyze the clinicopathological significance of miR-1307 in ovarian cancer. METHODS:MicroRNA microarray was used to screen differentially expressed microRNAs between th...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-015-0143-5
更新日期：2015-04-09 00:00:00
abstract：BACKGROUND:Our recent study on a panel of human ovarian cancer cells revealed that SKOV-3 cells barely express the Sprouty isoform 1 (Spry1) while 1A9 cells maintain it at a level similar to normal ovarian cells. Here we investigated the functional outcomes of induced alterations in the expression of Spry1 in the two c...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-7-61
更新日期：2014-06-08 00:00:00
abstract：BACKGROUND:Metformin decreases polycystic ovary syndrome (PCOS) symptoms, induces ovulation, and may improve developmental competence of in vitro oocyte maturation. This study was designed to define the effects of metformin on the characteristics of in vitro oocyte maturation in estradiol valerate (EV) PCOS-induced rat...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-015-0203-x
更新日期：2015-11-14 00:00:00
abstract：:As the human ovarian follicle enlarges in the course of a regular cycle or following controlled ovarian stimulation, the changes in its structure reveal the oocyte environment composed of cumulus oophorus cells and the follicular fluid (FF).In contrast to the dynamic nature of cells, the fluid compartment appears as a...
journal_title：Journal of ovarian research
pub_type： 杂志文章,评审
doi：10.1186/s13048-017-0342-3
更新日期：2017-07-12 00:00:00
abstract：BACKGROUND:The majority of death-related ovarian cancer is epithelial ovarian cancer (EOC). Regarding the Federation of Gynecology and Obstetrics (FIGO) stage IV EOC, the 5-year overall survival (OS) has not changed in last decades. Platelet (PLT) count and CA125 level are both prognostic markers that related to inflam...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-019-0544-y
更新日期：2019-07-31 00:00:00
abstract：PURPOSE:The conversion of androgens into estrogens by aromatase is called aromatization and is inhibited by aromatase inhibitors (AIs). The aim of this article is to evaluate the use of aromatase inhibitors in gynecological diseases such as endometriosis, leiomyoma, estrogen- dependent gynecologic neoplasia and inferti...
journal_title：Journal of ovarian research
pub_type： 杂志文章,评审
doi：10.1186/s13048-015-0131-9
更新日期：2015-02-25 00:00:00
abstract：BACKGROUND:Epithelial ovarian cancer has the highest fatality rate of all gynecologic malignancies. Although the majority of patients achieve complete clinical response after initial cytoreductive surgery and platinum-based chemotherapy, most recur and almost all will eventually acquire platinum-resistance for which tr...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-019-0506-4
更新日期：2019-04-25 00:00:00
abstract：INTRODUCTION:The use of patient reported outcome measures (PROMs) has increased during the past decade, and the focus on how to use them has resulted in a more proactive application. Studies have shown that proactive use of PROMs during treatment improves patient-clinician communication, leads to better symptom managem...
journal_title：Journal of ovarian research
pub_type： 杂志文章,评审
doi：10.1186/s13048-019-0538-9
更新日期：2019-07-15 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via the original article. ...
journal_title：Journal of ovarian research
pub_type： 已发布勘误
doi：10.1186/s13048-020-00733-5
更新日期：2020-11-12 00:00:00
abstract：BACKGROUND:The polycystic ovary syndrome (PCOS) affects approximately 6-10% of women of reproductive age and is characterized by chronic anovulation and hyperandrogenism. However, a comprehensive understanding of the mechanisms that dictate androgen overproduction is lacking, which may account for inconsistencies betwe...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-5-15
更新日期：2012-05-18 00:00:00
abstract：BACKGROUND:This study was aimed to explore the role of long noncoding RNA C17orf91 and its potential mechanisms in ovarian cancer development. RESULTS:To assess its role in ovarian cancer, microarray datasets (GSE14407, GSE30587, and GSE17260) in Gene Expression Omnibus (GEO) were utilized to assess the expression and...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-016-0258-3
更新日期：2016-08-17 00:00:00
abstract：BACKGROUND:Ovarian cancer (OC) was the primary malignant gynecological cancer and SNARE protein is closely related with tumor progression. Here, we identified SNAP23, a member of SNARE complex, as a potential oncogene in OC. METHODS:We determined the expression of SNAP23 in OC tissues and explored the clinical signifi...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-016-0289-9
更新日期：2016-11-17 00:00:00
abstract：:AbstractThe original article [1] contains errors in Figs. 6 and 8. The corrected figures can be shown ahead. ...
journal_title：Journal of ovarian research
pub_type： 杂志文章,已发布勘误
doi：10.1186/s13048-019-0487-3
更新日期：2019-01-30 00:00:00
abstract：BACKGROUND:The polycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine condition characterized by hyperandrogenism, hyperinsulinemia, insulin resistance and chronic anovulation. Regulation and interaction of a multitude of genes required for follicular development are found to be altered in PCOS. Micr...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-6-36
更新日期：2013-05-15 00:00:00
abstract：BACKGROUND:Ovarian hyperstimulation syndrome (OHSS) is a rare, yet severe, iatrogenic complication of ovulation induction therapy during assisted reproductive procedures. Our group previously detected atypical cells in the ascitic fluid of OHSS patients, although no malignancy developed during follow up. Here, the aim ...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-020-00624-9
更新日期：2020-03-05 00:00:00
abstract：OBJECTIVE:To review utilisation of elective embryo cryopreservation in the expectant management of patients at risk for developing ovarian hyperstimulation syndrome (OHSS), and report on reproductive outcome following transfer of thawed embryos. MATERIALS AND METHODS:Medical records were reviewed for patients undergoi...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-1-7
更新日期：2008-11-06 00:00:00
abstract：BACKGROUND:Low adiponectin levels in polycystic ovarian syndrome (PCOS) have been largely attributed to obesity which is common among these patients. In addition, evidence also suggests that low adiponectin in PCOS may be related to insulin resistance (IR) in these women. However, studies on the role of adiponectin in ...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-7-18
更新日期：2014-02-07 00:00:00
abstract：BACKGROUND:Ovarian hyperstimulation syndrome remains a serious complication during in vitro fertilization cycles if high dose human chorionic gonadotropin (hCG) is used to trigger ovulation in high responder patients. Though much of this risk is mitigated with trigger using gonadotropin releasing-hormone (GnRH) agonist...
journal_title：Journal of ovarian research
pub_type： 杂志文章,随机对照试验
doi：10.1186/s13048-019-0483-7
更新日期：2019-01-26 00:00:00
abstract：BACKGROUND:It is estimated that more than 20% of ovarian cancer cases are associated with a genetic predisposition that is only partially explained by germline mutations in the BRCA1 and BRCA2 genes. Recently, several pieces of evidence showed that mutations in three genes involved in the homologous recombination DNA r...
journal_title：Journal of ovarian research
pub_type： 杂志文章,meta分析
doi：10.1186/s13048-020-00654-3
更新日期：2020-05-02 00:00:00
abstract：BACKGROUND:Highly Individualized Egg Retrieval (HIER), defined as age-specific early oocyte retrieval (ER), has been demonstrated to avoid premature luteinization in women ≥43. We here investigated whether HIER also applies to younger women with premature ovarian aging (POA), and what best lead follicle size should be ...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-018-0398-8
更新日期：2018-03-16 00:00:00
abstract：:The diagnosis of primary angiosarcoma of ovary is still a challenge as it has no specific clinical symptoms and is easily confused with other malignant neoplasms in morphology. Here, we described a case of primary ovarian angiosarcoma and reviewed the literature. A 47-year-old female showed a left ovary mass. Grossly,...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-021-00771-7
更新日期：2021-01-28 00:00:00
