Abstract：
:Both estrogens and androgens are involved in the development and normal functioning of the ovaries. It is also known that ovarian function is regulated by diet. The goal of this study was to estimate the expression of sex hormone receptors in ovaries of mice that were on a 9-month caloric restriction (alternate-day feeding) as compared to normal control animals fed ad libitum. We found that prolonged caloric restriction in mouse ovaries led to increased expression of estrogen receptors (ERs) but did not affect expression of the androgen receptor (AR). This increase in ER:AR ration as result of caloric restriction may lead to higher sensitivity to estrogens and upon return to normal diet may increase ovulation. Thus our observation shed more light on a role of beneficial effect of calorie restriction on female reproduction.
journal_name
J Ovarian Resjournal_title
Journal of ovarian researchauthors
Słuczanowska-Głąbowska S,Laszczyńska M,Piotrowska K,Grabowska M,Grymuła K,Ratajczak MZdoi
10.1186/s13048-015-0185-8subject
Has Abstractpub_date
2015-08-13 00:00:00pages
57issn
1757-2215pii
10.1186/s13048-015-0185-8journal_volume
8pub_type
杂志文章abstract：BACKGROUND:Low adiponectin levels in polycystic ovarian syndrome (PCOS) have been largely attributed to obesity which is common among these patients. In addition, evidence also suggests that low adiponectin in PCOS may be related to insulin resistance (IR) in these women. However, studies on the role of adiponectin in ...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-7-18
更新日期：2014-02-07 00:00:00
abstract：:Following publication of the original article [1], the authors opted to correct the incorrect e-mail address of the corresponding author from 82-55-360-1850chungsu1982@gmail.com to chungsu1982@gmail.com , grant in the Acknowledgements section and Author details. Below are the updated version of the Acknowledgements an...
journal_title：Journal of ovarian research
pub_type： 已发布勘误
doi：10.1186/s13048-019-0540-2
更新日期：2019-07-23 00:00:00
abstract：BACKGROUND:The prevalence of obesity is increasing worldwide and significantly affects fertility and reproduction in both men and women. Our recent study has shown that excess body fat accelerates ovarian follicle development and follicle loss in rats. The aim of the present study is to explore the effect of SIRT1 acti...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-014-0097-z
更新日期：2014-10-21 00:00:00
abstract：BACKGROUND:Glutathione peroxidase 3 (GPX3) is a selenocysteine-containing antioxidant enzyme that reacts with hydrogen peroxide and soluble fatty acid hydroperoxides, thereby helping to maintain redox balance within cells. Serum levels of GPX3 have been found to be reduced in various cancers including prostrate, thyroi...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-4-18
更新日期：2011-10-22 00:00:00
abstract：OBJECTIVE:Recently, 14-3-3 zeta protein was identified as a potential serum biomarker of epithelial ovarian cancer (EOC). The goal of this study was to investigate the clinical potential of 14-3-3 zeta protein for monitoring EOC progression compared with CA-125 and HE4. DESIGN:Prospective follow-up study. SETTING:Uni...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-6-79
更新日期：2013-11-15 00:00:00
abstract：:The Publisher and Editor regretfully retract this article ( Hou W, Guan J, Lu H, Dong Q, Han Y, Zhang R. The effects of dexamethasone on the proliferation and apoptosis of human ovarian cancer cells induced by paclitaxel. J Ovarian Res. 2014;7:89) because the peer-review process was inappropriately influenced and comp...
journal_title：Journal of ovarian research
pub_type： 撤回出版物
doi：10.1186/s13048-015-0144-4
更新日期：2015-03-26 00:00:00
abstract：BACKGROUND:Hyaluronic acid is a prognostic factor in ovarian cancers. It is also a component of Hyaluronic Acid-Carboxymethyl Cellulose (HA-CMC) barrier, an anti-adhesion membrane widely used during abdominal surgeries in particular for ovarian carcinosis. 70% of patients who undergo ovarian surgery will relapse due to...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-7-40
更新日期：2014-04-16 00:00:00
abstract：INTRODUCTION:The use of patient reported outcome measures (PROMs) has increased during the past decade, and the focus on how to use them has resulted in a more proactive application. Studies have shown that proactive use of PROMs during treatment improves patient-clinician communication, leads to better symptom managem...
journal_title：Journal of ovarian research
pub_type： 杂志文章,评审
doi：10.1186/s13048-019-0538-9
更新日期：2019-07-15 00:00:00
abstract：BACKGROUND:Although agonistic autoantibodies against type-1 angiotensin-II receptor (AT1-AA) are frequently detected in women with preeclampsia, the clinical significance of AT1-AA in association with epithelial ovarian cancer (EOC) has not been identified. METHODS:In an attempt to clarify this issue, we measured seru...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-6-22
更新日期：2013-04-05 00:00:00
abstract：BACKGROUND:This study evaluated the influence of menstrual cycle length, menstrual cycle variability and predicted luteal phase length on the success of vitrified-warmed blastocyst transfer in natural menstrual cycle using progesterone for luteal phase supplementation. METHODS:Consecutive women undergoing vitrified-wa...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-018-0436-6
更新日期：2018-08-02 00:00:00
abstract：BACKGROUND:Ovarian cancer (OC) was the primary malignant gynecological cancer and SNARE protein is closely related with tumor progression. Here, we identified SNAP23, a member of SNARE complex, as a potential oncogene in OC. METHODS:We determined the expression of SNAP23 in OC tissues and explored the clinical signifi...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-016-0289-9
更新日期：2016-11-17 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via the original article. ...
journal_title：Journal of ovarian research
pub_type： 已发布勘误
doi：10.1186/s13048-020-00733-5
更新日期：2020-11-12 00:00:00
abstract：BACKGROUND:Ovarian hyperstimulation syndrome (OHSS) is a rare, yet severe, iatrogenic complication of ovulation induction therapy during assisted reproductive procedures. Our group previously detected atypical cells in the ascitic fluid of OHSS patients, although no malignancy developed during follow up. Here, the aim ...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-020-00624-9
更新日期：2020-03-05 00:00:00
abstract：BACKGROUND:galectin-1 has been implicated in tumor invasion and metastasis and is frequently over-expressed in epithelial ovarian cancer (EOC), but its potential as a biomarker remains unclear. In this novel study, we have explored the possible use of galectin-1 as a biomarker for EOC. METHODS:galectin-1 in sera was e...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-015-0206-7
更新日期：2015-11-21 00:00:00
abstract：:Currently, the world is in the seventh month of the COVID-19 pandemic. Globally, infections with novel SARS-CoV-2 virus are continuously rising with mounting numbers of deaths. International and local public health responses, almost in synchrony, imposed restrictions to minimize spread of the virus, overload of health...
journal_title：Journal of ovarian research
pub_type： 杂志文章,评审
doi：10.1186/s13048-020-00737-1
更新日期：2020-11-27 00:00:00
abstract：BACKGROUND:Myo-inositol (MI), successfully used in polycystic ovary syndrome (PCOS), was administered with α-LA to exploit its action of favouring the passage of other molecules through biological barriers, and also considering its anti-inflammatory effect. METHODS:PCOS patients, according to the Rotterdam ESHRE-ASRM ...
journal_title：Journal of ovarian research
pub_type： 临床试验,杂志文章
doi：10.1186/s13048-018-0411-2
更新日期：2018-05-10 00:00:00
abstract：BACKGROUND:The polycystic ovary syndrome (PCOS) affects approximately 6-10% of women of reproductive age and is characterized by chronic anovulation and hyperandrogenism. However, a comprehensive understanding of the mechanisms that dictate androgen overproduction is lacking, which may account for inconsistencies betwe...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-5-15
更新日期：2012-05-18 00:00:00
abstract：BACKGROUND:The imbalance of expression of microRNA-802 may have a significant place in tumor progression. However, the bio-function of epithelial ovarian cancer cells remains unclear. Therefore, we setup this study to explore the pathogenesis of epithelial ovarian cancer based on microRNA-802. METHODS:RT-qPCR analysis...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-019-0576-3
更新日期：2019-10-22 00:00:00
abstract：BACKGROUND:Recent studies have shown that microRNAs may regulate the ABCB1 gene (ATP-binding cassette, sub-family B [MDR/TAP], member 1). Computational programs have predicted that the 3'-untranslated region (3'-UTR) of ABCB1 contains a potential miRNA-binding site for miR-186. Here, we investigated the role of miR-186...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-015-0207-6
更新日期：2015-12-02 00:00:00
abstract：BACKGROUND:Degeneration of ovarian function is an obvious feature of female aging. In addition, studies have shown that autophagy decreases with age, and DNA methylation is a hallmark epigenetic pattern during aging. However, it is not clear whether the expression and DNA methylation of autophagy genes are involved in ...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-020-0615-0
更新日期：2020-02-03 00:00:00
abstract：BACKGROUND:The down-regulation of E-cadherin gene (CDH1) expression has been regarded as an important event in cancer invasion and metastasis. However, the association between CDH1 promoter methylation and ovarian cancer remains unclear. A meta-analysis was conducted to evaluate the potential role of CDH1 promoter meth...
journal_title：Journal of ovarian research
pub_type： 杂志文章,meta分析
doi：10.1186/s13048-016-0231-1
更新日期：2016-04-11 00:00:00
abstract：:RNA methylation can reverse the methylation modification at the RNA level, which is an extremely important epigenetic modification. The function and mechanism of YTHDF2, as a reader of m6A modification, in epithelial ovarian cancer (EOC) have not been elucidated so far. This study aimed to investigate how YTHDF2 and m...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-020-00717-5
更新日期：2020-09-18 00:00:00
abstract：OBJECTIVE:To review utilisation of elective embryo cryopreservation in the expectant management of patients at risk for developing ovarian hyperstimulation syndrome (OHSS), and report on reproductive outcome following transfer of thawed embryos. MATERIALS AND METHODS:Medical records were reviewed for patients undergoi...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-1-7
更新日期：2008-11-06 00:00:00
abstract：BACKGROUND:We aimed to examine the expression of miR-1307 in chemosensitive and chemoresistant epithelial ovarian cancer tissues and cell lines and to analyze the clinicopathological significance of miR-1307 in ovarian cancer. METHODS:MicroRNA microarray was used to screen differentially expressed microRNAs between th...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-015-0143-5
更新日期：2015-04-09 00:00:00
abstract：INTRODUCTION:Weight gain and fat accumulation are predisposing factors of PCOS. Life-style modification, including increasing physical activity, is the first line approach in managing PCOS. The objective of this study is to assess the effect of exercise intensity on weight changes, androstenedione and free testosterone...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-7-37
更新日期：2014-04-08 00:00:00
abstract：BACKGROUND:Mature cystic teratomas are usually found in the ovaries. They are bilateral in 10 to 15% of cases and multiple cystic teratomas may be present in one ovary. The aim of this study is to clarify if development of mature cystic teratomas of the ovaries in a single host is metachronous or due to autoimplant or ...
journal_title：Journal of ovarian research
pub_type： 杂志文章,评审
doi：10.1186/s13048-017-0313-8
更新日期：2017-03-14 00:00:00
abstract：BACKGROUND:Hypertensive disorders of pregnancy are the most common causes of adverse maternal & perinatal outcomes. Such investigations in resource limited settings would help to have great design strategies in preventing maternal and perinatal morbidity and mortality. AIM:To determine management outcome and factor as...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-015-0135-5
更新日期：2015-03-15 00:00:00
abstract：BACKGROUNDS:Long non-coding RNA is a novel group of non-protein coding transcripts over 200 nt in length. Recent studies have found that they are widely involved in many pathological and physiological processes. In our previous study, we found that lnc-GULP1-2:1 was significantly down-regulated in the ovarian cortical ...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-021-00769-1
更新日期：2021-01-20 00:00:00
abstract：BACKGROUND:The ST6Gal-I glycosyltransferase, which adds α2-6-linked sialic acids to N-glycosylated proteins is upregulated in a wide range of malignancies including ovarian cancer. Prior studies have shown that ST6Gal-I-mediated sialylation of select surface receptors remodels intracellular signaling to impart cancer s...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-019-0574-5
更新日期：2019-10-14 00:00:00
abstract：BACKGROUND:It is estimated that more than 20% of ovarian cancer cases are associated with a genetic predisposition that is only partially explained by germline mutations in the BRCA1 and BRCA2 genes. Recently, several pieces of evidence showed that mutations in three genes involved in the homologous recombination DNA r...
journal_title：Journal of ovarian research
pub_type： 杂志文章,meta分析
doi：10.1186/s13048-020-00654-3
更新日期：2020-05-02 00:00:00
