Decreased ovarian function and autophagy gene methylation in aging rats.

abstract：:An amendment to this paper has been published and can be accessed via the original article. ...

journal_title：Journal of ovarian research

authors： Gao Z,Ma X,Liu J,Ge Y,Wang L,Fu P,Liu Z,Yao R,Yan X

更新日期：2020-11-12 00:00:00

abstract：BACKGROUND:To investigate dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) for assessing histopathological and molecular biological features in induced rat epithelial ovarian carcinomas (EOCs). METHODS:7,12-dimethylbenz[A]anthracene (DMBA) was applied to induce EOCs in situ in 46 SD rats. Conventional MR...

journal_title：Journal of ovarian research

authors： Yuan SJ,Qiao TK,Qiang JW,Cai SQ,Li RK

更新日期：2017-09-26 00:00:00

abstract：BACKGROUND:Low adiponectin levels in polycystic ovarian syndrome (PCOS) have been largely attributed to obesity which is common among these patients. In addition, evidence also suggests that low adiponectin in PCOS may be related to insulin resistance (IR) in these women. However, studies on the role of adiponectin in ...

journal_title：Journal of ovarian research

authors： Mirza SS,Shafique K,Shaikh AR,Khan NA,Anwar Qureshi M

更新日期：2014-02-07 00:00:00

abstract：:The diagnosis of primary angiosarcoma of ovary is still a challenge as it has no specific clinical symptoms and is easily confused with other malignant neoplasms in morphology. Here, we described a case of primary ovarian angiosarcoma and reviewed the literature. A 47-year-old female showed a left ovary mass. Grossly,...

journal_title：Journal of ovarian research

authors： Ye H,Lin M,Li R,Qin S,Hou G,Chen H,Li X

更新日期：2021-01-28 00:00:00

abstract：BACKGROUND:Myo-inositol (MI), successfully used in polycystic ovary syndrome (PCOS), was administered with α-LA to exploit its action of favouring the passage of other molecules through biological barriers, and also considering its anti-inflammatory effect. METHODS:PCOS patients, according to the Rotterdam ESHRE-ASRM ...

journal_title：Journal of ovarian research

authors： Montanino Oliva M,Buonomo G,Calcagno M,Unfer V

更新日期：2018-05-10 00:00:00

abstract：BACKGROUND:Altered androgen hormone homeostasis and androgen receptor (AR) activity have been implicated in ovarian carcinogenesis but the relationship between AR expression in ovarian cancer and clinical outcome remains unclear. METHODS:In this study, the prognostic impact of AR expression was investigated using immu...

journal_title：Journal of ovarian research

authors： Nodin B,Zendehrokh N,Brändstedt J,Nilsson E,Manjer J,Brennan DJ,Jirström K

更新日期：2010-06-17 00:00:00

abstract：BACKGROUND:Polycystic Ovary Syndrome (PCOS) is a widespread reproductive disorder characterized by a disruption of follicular growth and anovulatory infertility. In women with PCOS, follicular growth and ovulation can be induced by subcutaneous injections of low doses of follicle stimulating hormone (FSH). The aim of t...

journal_title：Journal of ovarian research

authors： Tessaro I,Modina SC,Franciosi F,Sivelli G,Terzaghi L,Lodde V,Luciano AM

更新日期：2015-10-06 00:00:00

abstract：BACKGROUND:This study aimed to identify the clinical and pathological characteristics and the possible prognostic factors for Chinese patients with early-stage ovarian endometrioid carcinoma. METHODS:The present study reviewed the medical records of patients who received initial treatment and a postoperative pathologi...

journal_title：Journal of ovarian research

authors： Zhao Y,Wang S,Qu YM,Ji YT,Shen K,Lang JH

更新日期：2017-09-18 00:00:00

abstract：BACKGROUND:The polycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine condition characterized by hyperandrogenism, hyperinsulinemia, insulin resistance and chronic anovulation. Regulation and interaction of a multitude of genes required for follicular development are found to be altered in PCOS. Micr...

journal_title：Journal of ovarian research

authors： Hossain MM,Cao M,Wang Q,Kim JY,Schellander K,Tesfaye D,Tsang BK

更新日期：2013-05-15 00:00:00

abstract：:Following publication of the original article [1], the authors opted to correct the incorrect e-mail address of the corresponding author from 82-55-360-1850chungsu1982@gmail.com to chungsu1982@gmail.com , grant in the Acknowledgements section and Author details. Below are the updated version of the Acknowledgements an...

journal_title：Journal of ovarian research

authors： Kim KH,Choi KU,Kim A,Lee SJ,Lee JH,Suh DS,Kwon BS,Hwang C

更新日期：2019-07-23 00:00:00

abstract：BACKGROUND:This study evaluated the influence of menstrual cycle length, menstrual cycle variability and predicted luteal phase length on the success of vitrified-warmed blastocyst transfer in natural menstrual cycle using progesterone for luteal phase supplementation. METHODS:Consecutive women undergoing vitrified-wa...

journal_title：Journal of ovarian research

authors： Reljič M,Knez J

更新日期：2018-08-02 00:00:00

abstract：:Currently, the world is in the seventh month of the COVID-19 pandemic. Globally, infections with novel SARS-CoV-2 virus are continuously rising with mounting numbers of deaths. International and local public health responses, almost in synchrony, imposed restrictions to minimize spread of the virus, overload of health...

journal_title：Journal of ovarian research

authors： Madjunkov M,Dviri M,Librach C

更新日期：2020-11-27 00:00:00

abstract：BACKGROUND:Neovascularization is necessary for follicular growth. Vascularization is first observed in preantral follicles, and thereafter the vasculature markedly increases in follicles undergoing development. Neovascularization includes angiogenesis and vasculogenesis. Vasculogenesis is the formation of new blood ves...

journal_title：Journal of ovarian research

authors： Kizuka-Shibuya F,Tokuda N,Takagi K,Adachi Y,Lee L,Tamura I,Maekawa R,Tamura H,Suzuki T,Owada Y,Sugino N

更新日期：2014-01-21 00:00:00

abstract：BACKGROUND:galectin-1 has been implicated in tumor invasion and metastasis and is frequently over-expressed in epithelial ovarian cancer (EOC), but its potential as a biomarker remains unclear. In this novel study, we have explored the possible use of galectin-1 as a biomarker for EOC. METHODS:galectin-1 in sera was e...

journal_title：Journal of ovarian research

authors： Chen L,Yao Y,Sun L,Zhou J,Liu J,Wang J,Li J,Tang J

更新日期：2015-11-21 00:00:00

abstract：:High-Grade Serous Ovarian Carcinoma (HGSOC) is the predominant histotype of epithelial ovarian cancer (EOC), characterized by advanced stage at diagnosis, frequent TP53 mutation, rapid progression, and high responsiveness to platinum-based-chemotherapy. To date, standard first-line-chemotherapy in advanced EOC include...

journal_title：Journal of ovarian research

authors： Mignogna C,Staropoli N,Botta C,De Marco C,Rizzuto A,Morelli M,Di Cello A,Franco R,Camastra C,Presta I,Malara N,Salvino A,Tassone P,Tagliaferri P,Barni T,Donato G,Di Vito A

更新日期：2016-05-21 00:00:00

abstract：INTRODUCTION:Weight gain and fat accumulation are predisposing factors of PCOS. Life-style modification, including increasing physical activity, is the first line approach in managing PCOS. The objective of this study is to assess the effect of exercise intensity on weight changes, androstenedione and free testosterone...

journal_title：Journal of ovarian research

authors： Miri M,Karimi Jashni H,Alipour F

更新日期：2014-04-08 00:00:00

abstract：BACKGROUND:Hyaluronic acid is a prognostic factor in ovarian cancers. It is also a component of Hyaluronic Acid-Carboxymethyl Cellulose (HA-CMC) barrier, an anti-adhesion membrane widely used during abdominal surgeries in particular for ovarian carcinosis. 70% of patients who undergo ovarian surgery will relapse due to...

journal_title：Journal of ovarian research

authors： Picaud L,Thibault B,Mery E,Ouali M,Martinez A,Delord JP,Couderc B,Ferron G

更新日期：2014-04-16 00:00:00

abstract：BACKGROUND:The imbalance of expression of microRNA-802 may have a significant place in tumor progression. However, the bio-function of epithelial ovarian cancer cells remains unclear. Therefore, we setup this study to explore the pathogenesis of epithelial ovarian cancer based on microRNA-802. METHODS:RT-qPCR analysis...

journal_title：Journal of ovarian research

authors： Yang B,Sun L,Liang L

更新日期：2019-10-22 00:00:00

abstract：BACKGROUND:This study was designed to investigate leptin levels in the fluid in ovarian endometriomas (OEs) and to compare the expression of leptin and its receptors (OBR) in ovarian tissue affected by endometrioma in infertile women to its expression in the normal ovarian tissue of fertile controls without endometrios...

journal_title：Journal of ovarian research

authors： Zendron C,Gonçalves HF,Cavalcante FS,Pereira TR,Evangelista A,Ramos CF,Oliveira MA

更新日期：2014-01-08 00:00:00

abstract：BACKGROUND:Glutathione peroxidase 3 (GPX3) is a selenocysteine-containing antioxidant enzyme that reacts with hydrogen peroxide and soluble fatty acid hydroperoxides, thereby helping to maintain redox balance within cells. Serum levels of GPX3 have been found to be reduced in various cancers including prostrate, thyroi...

journal_title：Journal of ovarian research

authors： Agnani D,Camacho-Vanegas O,Camacho C,Lele S,Odunsi K,Cohen S,Dottino P,Martignetti JA

更新日期：2011-10-22 00:00:00

abstract：BACKGROUND:Gonadoblastoma (GB) is a rare mixed germ cell-sex cord-stromal tumour, first described in humans, commonly found in dysgenetic gonads of intersex patients that have a Y chromosome. However, this entity in not recognized in the WHO classification of tumours of genital system of domestic animals. Herein, we de...

journal_title：Journal of ovarian research

authors： Flores AR,Lobo J,Nunes F,Rêma A,Lopes P,Carvalho L,Bartosch C,Amorim I,Gärtner F

更新日期：2019-09-23 00:00:00

abstract：BACKGROUND:The use of long protocol during controlled ovarian stimulation for assisted reproduction attracts high dosage of gonadotropins. High dose of gonadotropins can be detrimental to oocyte development, which affects its quality and compromises the treatment outcome. Mild stimulation protocols that attract low dos...

journal_title：Journal of ovarian research

authors： Ochin H,Ma X,Wang L,Li X,Song J,Meng Y,Shen J,Cui YG,Liu J

更新日期：2018-05-04 00:00:00

abstract：:RNA methylation can reverse the methylation modification at the RNA level, which is an extremely important epigenetic modification. The function and mechanism of YTHDF2, as a reader of m6A modification, in epithelial ovarian cancer (EOC) have not been elucidated so far. This study aimed to investigate how YTHDF2 and m...

journal_title：Journal of ovarian research

authors： Li J,Wu L,Pei M,Zhang Y

更新日期：2020-09-18 00:00:00

abstract：BACKGROUND:Ovarian hyperstimulation syndrome (OHSS) is a rare, yet severe, iatrogenic complication of ovulation induction therapy during assisted reproductive procedures. Our group previously detected atypical cells in the ascitic fluid of OHSS patients, although no malignancy developed during follow up. Here, the aim ...

journal_title：Journal of ovarian research

authors： Farkas B,Boldizsar F,Bohonyi N,Farkas N,Marczi S,Kovacs GL,Bodis J,Koppan M

更新日期：2020-03-05 00:00:00

abstract：BACKGROUND:Mucinous carcinomas from different organs are morphologically similar and might share similarities at the molecular and biochemical levels that may illuminate their pathogenesis and influence management. The factors involved in the pathogenesis of mucinous carcinomas remain unknown; which is likely one contr...

journal_title：Journal of ovarian research

authors： Desouki MM,Franklin RB,Costello LC,Fadare O

更新日期：2015-06-17 00:00:00

abstract：BACKGROUND:Recent studies have shown that microRNAs may regulate the ABCB1 gene (ATP-binding cassette, sub-family B [MDR/TAP], member 1). Computational programs have predicted that the 3'-untranslated region (3'-UTR) of ABCB1 contains a potential miRNA-binding site for miR-186. Here, we investigated the role of miR-186...

journal_title：Journal of ovarian research

authors： Sun KX,Jiao JW,Chen S,Liu BL,Zhao Y

更新日期：2015-12-02 00:00:00

abstract：BACKGROUNDS:Long non-coding RNA is a novel group of non-protein coding transcripts over 200 nt in length. Recent studies have found that they are widely involved in many pathological and physiological processes. In our previous study, we found that lnc-GULP1-2:1 was significantly down-regulated in the ovarian cortical ...

journal_title：Journal of ovarian research

authors： Yao G,Kong Y,Yang G,Kong D,Xu Y,He J,Xu Z,Bai Y,Fan H,He Q,Sun Y

更新日期：2021-01-20 00:00:00

abstract：UNLABELLED: BACKGROUND:To investigate the 3.0-Tesla (3 T) magnetic resonance imaging (MRI) characteristics of primary adnexal lesions for discriminating benign from malignant lesions. METHODS:One hundred thirty-nine patients with pathologically proven primary adnexal masses referred for 3 T MRI assessment preoperativ...

journal_title：Journal of ovarian research

authors： Zhang H,Zhang GF,He ZY,Li ZY,Zhu M,Zhang GX

更新日期：2012-11-14 00:00:00

abstract：BACKGROUND:Upregulation of Cyclin dependent kinase 1 (CDK1) protein is closely related with the prognosis of several malignant tumors. Chk1-CDC25C-CDK1 signaling and P53-P21WAF1-CDK1 signaling pathways are closely related with the cell cycle G2/M phase regulation. The present study aimed to analyze the relationship bet...

journal_title：Journal of ovarian research

authors： Zhang R,Shi H,Ren F,Zhang M,Ji P,Wang W,Liu C

更新日期：2017-09-12 00:00:00

abstract：BACKGROUND:Our recent study on a panel of human ovarian cancer cells revealed that SKOV-3 cells barely express the Sprouty isoform 1 (Spry1) while 1A9 cells maintain it at a level similar to normal ovarian cells. Here we investigated the functional outcomes of induced alterations in the expression of Spry1 in the two c...

journal_title：Journal of ovarian research

authors： Masoumi-Moghaddam S,Amini A,Ehteda A,Wei AQ,Morris DL

更新日期：2014-06-08 00:00:00