Altered expression of miRNAs in a dihydrotestosterone-induced rat PCOS model.

abstract：BACKGROUND:To demonstrate the use of surface-enhanced Raman spectroscopy (SERS) to determine sialic acid (SA) levels in saliva using silver nanoparticles as substrates, in adnexal mass patients scheduled for surgical intervention to remove invasive masses, with the aim to compare SA levels in benign tumor vs ovarian ca...

journal_title：Journal of ovarian research

authors： Zermeño-Nava JJ,Martínez-Martínez MU,Rámirez-de-Ávila AL,Hernández-Arteaga AC,García-Valdivieso MG,Hernández-Cedillo A,José-Yacamán M,Navarro-Contreras HR

更新日期：2018-07-24 00:00:00

abstract：BACKGROUND:Polycystic Ovary Syndrome (PCOS) is a widespread reproductive disorder characterized by a disruption of follicular growth and anovulatory infertility. In women with PCOS, follicular growth and ovulation can be induced by subcutaneous injections of low doses of follicle stimulating hormone (FSH). The aim of t...

journal_title：Journal of ovarian research

authors： Tessaro I,Modina SC,Franciosi F,Sivelli G,Terzaghi L,Lodde V,Luciano AM

更新日期：2015-10-06 00:00:00

abstract：BACKGROUND:To investigate dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) for assessing histopathological and molecular biological features in induced rat epithelial ovarian carcinomas (EOCs). METHODS:7,12-dimethylbenz[A]anthracene (DMBA) was applied to induce EOCs in situ in 46 SD rats. Conventional MR...

journal_title：Journal of ovarian research

authors： Yuan SJ,Qiao TK,Qiang JW,Cai SQ,Li RK

更新日期：2017-09-26 00:00:00

abstract：BACKGROUND:Recent studies have shown that microRNAs may regulate the ABCB1 gene (ATP-binding cassette, sub-family B [MDR/TAP], member 1). Computational programs have predicted that the 3'-untranslated region (3'-UTR) of ABCB1 contains a potential miRNA-binding site for miR-186. Here, we investigated the role of miR-186...

journal_title：Journal of ovarian research

authors： Sun KX,Jiao JW,Chen S,Liu BL,Zhao Y

更新日期：2015-12-02 00:00:00

abstract：BACKGROUND:Various components of the immune system play a critical role in the prognosis and treatment response in ovarian cancer (OC). Immunotherapy has been recognized as a hallmark of cancer but the effect is contradictional. Reliable immune gene-based prognostic biomarkers or regulatory factors are necessary to be ...

journal_title：Journal of ovarian research

authors： Cao T,Shen H

更新日期：2021-01-28 00:00:00

abstract：:Ovarian hyperstimulation syndrome (OHSS) is a serious complication of controlled ovarian hyperstimulation (COH). The syndrome almost always presents either after hCG administration in susceptible patients or during early pregnancy. Despite many years of clinical experience, there are no precise methods to completely p...

journal_title：Journal of ovarian research

authors： Orvieto R

更新日期：2013-11-05 00:00:00

abstract：BACKGROUND:Hypertensive disorders of pregnancy are the most common causes of adverse maternal & perinatal outcomes. Such investigations in resource limited settings would help to have great design strategies in preventing maternal and perinatal morbidity and mortality. AIM:To determine management outcome and factor as...

journal_title：Journal of ovarian research

authors： Seyom E,Abera M,Tesfaye M,Fentahun N

更新日期：2015-03-15 00:00:00

abstract：:Previously anecdotally observed rebounds in follicle growth after interruption of exogenous gonadotropins in absolute non-responders were the impetus for here reported study. In a prospective cohort study, we investigated 49 consecutive patients, absolutely unresponsive to maximal exogenous gonadotropin stimulation, f...

journal_title：Journal of ovarian research

authors： Gleicher N,Weghofer A,Darmon SK,Barad DH

更新日期：2021-01-09 00:00:00

abstract：BACKGROUND:In this study we aimed to identify a prognostic signature in BRCA1/2 mutations to predict disease progression and the efficiency of chemotherapy ovarian cancer (OV), the second most common cause of death from gynecologic cancer in women worldwide. METHODS:Univariate Cox proportional-hazards and multivariate...

journal_title：Journal of ovarian research

authors： Pan Y,Jia LP,Liu Y,Han Y,Li Q,Zou Q,Zhang Z,Huang J,Deng Q

更新日期：2020-09-19 00:00:00

abstract：BACKGROUNDS:Long non-coding RNA is a novel group of non-protein coding transcripts over 200 nt in length. Recent studies have found that they are widely involved in many pathological and physiological processes. In our previous study, we found that lnc-GULP1-2:1 was significantly down-regulated in the ovarian cortical ...

journal_title：Journal of ovarian research

authors： Yao G,Kong Y,Yang G,Kong D,Xu Y,He J,Xu Z,Bai Y,Fan H,He Q,Sun Y

更新日期：2021-01-20 00:00:00

abstract：:Ovarian cancer is the fifth most common cause of cancer death in women and the leading cause of death from gynaecological malignancies. Of the 75% women diagnosed with locally advanced or disseminated disease, only 30% will survive five years following treatment. This poor prognosis is due to the following reasons: li...

journal_title：Journal of ovarian research

authors： Jacob F,Nixdorf S,Hacker NF,Heinzelmann-Schwarz VA

更新日期：2014-06-07 00:00:00

abstract：UNLABELLED: BACKGROUND:Women with polycystic ovary syndrome (PCOS) have higher risk for cardiovascular disease (CVD). Heart type fatty acid binding protein (HFABP) has been found to be predictive for myocardial ischemia.Wet ested whether HFABP is the predictor for CVD in PCOS patients, who have an increased risk of ca...

journal_title：Journal of ovarian research

authors： Cakir E,Ozbek M,Sahin M,Cakal E,Gungunes A,Ginis Z,Demirci T,Delibasi T

更新日期：2012-12-18 00:00:00

abstract：BACKGROUND:Mature cystic teratomas are usually found in the ovaries. They are bilateral in 10 to 15% of cases and multiple cystic teratomas may be present in one ovary. The aim of this study is to clarify if development of mature cystic teratomas of the ovaries in a single host is metachronous or due to autoimplant or ...

journal_title：Journal of ovarian research

authors： Wang WC,Lai YC

更新日期：2017-03-14 00:00:00

abstract：:We have earlier reported the presence of very small embryonic-like stem cells (VSELs) in adult mouse uterus along with slightly bigger progenitors termed endometrial stem cells (EnSCs) and their regulation by ovarian hormones thus demonstrating a crucial role played by them during proliferation, differentiation and re...

journal_title：Journal of ovarian research

authors： Bhartiya D,James K

更新日期：2017-04-24 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the impact of metabolic parameters in the peritoneal cavity on the likelihood of achieving complete tumor debulking in patients with ovarian and peritoneal cancers. MATERIALS AND METHODS:Forty-nine patients with ovarian and peritoneal cancers were included, who underwent pre-operat...

journal_title：Journal of ovarian research

authors： Tsoi TT,Chiu KWH,Chu MY,Ngan HYS,Lee EYP

更新日期：2020-05-20 00:00:00

abstract：:Growing evidence indicates that the tumor biomarker cytokeratin 19 fragment (CYFRA21-1) is significant for a variety of cancers. However, its role in epithelial ovarian cancer (EOC) has rarely been reported. In this study, a receiver operating characteristic (ROC) curve was utilized to estimate the diagnostic efficien...

journal_title：Journal of ovarian research

authors： Jin C,Yang M,Han X,Chu H,Zhang Y,Lu M,Wang Z,Xu X,Liu W,Wang F,Ju S

更新日期：2019-11-25 00:00:00

abstract：BACKGROUND:Hyaluronic acid is a prognostic factor in ovarian cancers. It is also a component of Hyaluronic Acid-Carboxymethyl Cellulose (HA-CMC) barrier, an anti-adhesion membrane widely used during abdominal surgeries in particular for ovarian carcinosis. 70% of patients who undergo ovarian surgery will relapse due to...

journal_title：Journal of ovarian research

authors： Picaud L,Thibault B,Mery E,Ouali M,Martinez A,Delord JP,Couderc B,Ferron G

更新日期：2014-04-16 00:00:00

abstract：BACKGROUND:Myo-inositol (MI), successfully used in polycystic ovary syndrome (PCOS), was administered with α-LA to exploit its action of favouring the passage of other molecules through biological barriers, and also considering its anti-inflammatory effect. METHODS:PCOS patients, according to the Rotterdam ESHRE-ASRM ...

journal_title：Journal of ovarian research

authors： Montanino Oliva M,Buonomo G,Calcagno M,Unfer V

更新日期：2018-05-10 00:00:00

abstract：BACKGROUND:Whether there is a mechanistic link between FOLR1 and response to cisplatin has not been extensively examined. In this study, we determine the expression of FOLR1 in ovarian cancer and examine if FOLR1 levels influence response to cisplatin. RESULTS:(1) FOLR1 protein expression was lowest in normal ovarian ...

journal_title：Journal of ovarian research

authors： Huang MJ,Zhang W,Wang Q,Yang ZJ,Liao SB,Li L

更新日期：2018-02-13 00:00:00

abstract：:As the human ovarian follicle enlarges in the course of a regular cycle or following controlled ovarian stimulation, the changes in its structure reveal the oocyte environment composed of cumulus oophorus cells and the follicular fluid (FF).In contrast to the dynamic nature of cells, the fluid compartment appears as a...

journal_title：Journal of ovarian research

authors： Freitas C,Neto AC,Matos L,Silva E,Ribeiro Â,Silva-Carvalho JL,Almeida H

更新日期：2017-07-12 00:00:00

abstract：UNLABELLED: BACKGROUND:To investigate the 3.0-Tesla (3 T) magnetic resonance imaging (MRI) characteristics of primary adnexal lesions for discriminating benign from malignant lesions. METHODS:One hundred thirty-nine patients with pathologically proven primary adnexal masses referred for 3 T MRI assessment preoperativ...

journal_title：Journal of ovarian research

authors： Zhang H,Zhang GF,He ZY,Li ZY,Zhu M,Zhang GX

更新日期：2012-11-14 00:00:00

abstract：BACKGROUND:Standard morphologic evaluation has been the most widely adopted approach to embryo selection, and remains the most common strategy.The objective of the study to determine the association between the morphologic grading and implantation rate of euploid blastocysts in single frozen-thawed embryo transfer (SET...

journal_title：Journal of ovarian research

authors： Lou H,Li N,Guan Y,Zhang Y,Hao D,Cui S

更新日期：2021-01-23 00:00:00

abstract：BACKGROUND:Despite advances in surgical aggressiveness and conventional chemotherapy, ovarian cancer remains the most lethal cause of gynecologic cancer mortality; consequently there is a need for new therapeutic agents and innovative treatment paradigms for the treatment of ovarian cancer. Several studies have demonst...

journal_title：Journal of ovarian research

authors： Thomas ED,Meza-Perez S,Bevis KS,Randall TD,Gillespie GY,Langford C,Alvarez RD

更新日期：2016-10-27 00:00:00

abstract：BACKGROUND:Ovarian cancer (OC) was the primary malignant gynecological cancer and SNARE protein is closely related with tumor progression. Here, we identified SNAP23, a member of SNARE complex, as a potential oncogene in OC. METHODS:We determined the expression of SNAP23 in OC tissues and explored the clinical signifi...

journal_title：Journal of ovarian research

authors： Sun Q,Huang X,Zhang Q,Qu J,Shen Y,Wang X,Sun H,Wang J,Xu L,Chen X,Ren B

更新日期：2016-11-17 00:00:00

abstract：BACKGROUND:Gonadoblastoma (GB) is a rare mixed germ cell-sex cord-stromal tumour, first described in humans, commonly found in dysgenetic gonads of intersex patients that have a Y chromosome. However, this entity in not recognized in the WHO classification of tumours of genital system of domestic animals. Herein, we de...

journal_title：Journal of ovarian research

authors： Flores AR,Lobo J,Nunes F,Rêma A,Lopes P,Carvalho L,Bartosch C,Amorim I,Gärtner F

更新日期：2019-09-23 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via the original article. ...

journal_title：Journal of ovarian research

authors： Gao Z,Ma X,Liu J,Ge Y,Wang L,Fu P,Liu Z,Yao R,Yan X

更新日期：2020-11-12 00:00:00

abstract：INTRODUCTION:The use of patient reported outcome measures (PROMs) has increased during the past decade, and the focus on how to use them has resulted in a more proactive application. Studies have shown that proactive use of PROMs during treatment improves patient-clinician communication, leads to better symptom managem...

journal_title：Journal of ovarian research

authors： Kargo AS,Coulter A,Jensen PT,Steffensen KD

更新日期：2019-07-15 00:00:00

abstract：:RNA methylation can reverse the methylation modification at the RNA level, which is an extremely important epigenetic modification. The function and mechanism of YTHDF2, as a reader of m6A modification, in epithelial ovarian cancer (EOC) have not been elucidated so far. This study aimed to investigate how YTHDF2 and m...

journal_title：Journal of ovarian research

authors： Li J,Wu L,Pei M,Zhang Y

更新日期：2020-09-18 00:00:00

abstract：BACKGROUND:Ovarian hyperstimulation syndrome (OHSS) is a rare, yet severe, iatrogenic complication of ovulation induction therapy during assisted reproductive procedures. Our group previously detected atypical cells in the ascitic fluid of OHSS patients, although no malignancy developed during follow up. Here, the aim ...

journal_title：Journal of ovarian research

authors： Farkas B,Boldizsar F,Bohonyi N,Farkas N,Marczi S,Kovacs GL,Bodis J,Koppan M

更新日期：2020-03-05 00:00:00

abstract：BACKGROUND:It is estimated that more than 20% of ovarian cancer cases are associated with a genetic predisposition that is only partially explained by germline mutations in the BRCA1 and BRCA2 genes. Recently, several pieces of evidence showed that mutations in three genes involved in the homologous recombination DNA r...

journal_title：Journal of ovarian research

authors： Suszynska M,Ratajska M,Kozlowski P

更新日期：2020-05-02 00:00:00