Abstract：
PURPOSE:The conversion of androgens into estrogens by aromatase is called aromatization and is inhibited by aromatase inhibitors (AIs). The aim of this article is to evaluate the use of aromatase inhibitors in gynecological diseases such as endometriosis, leiomyoma, estrogen- dependent gynecologic neoplasia and infertility. METHODS:This is a review of literature combined with experience and use of aromatase inhibitors ın practıce of gynecology. CONCLUSION:AIs are promising agents in treatment of estrogen dependent disease. However lack of experience, side effects and cost are limiting factors for using these agents in infertility treatment. However there is need for larger, well designed randomized trials to generate robust data in order to establish the true potential of aromatase inhibitors.
journal_name
J Ovarian Resjournal_title
Journal of ovarian researchauthors
Usluogullari B,Duvan C,Usluogullari Cdoi
10.1186/s13048-015-0131-9subject
Has Abstractpub_date
2015-02-25 00:00:00pages
4issn
1757-2215pii
s13048-015-0131-9journal_volume
8pub_type
杂志文章,评审abstract：:Growing evidence indicates that the tumor biomarker cytokeratin 19 fragment (CYFRA21-1) is significant for a variety of cancers. However, its role in epithelial ovarian cancer (EOC) has rarely been reported. In this study, a receiver operating characteristic (ROC) curve was utilized to estimate the diagnostic efficien...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-019-0587-0
更新日期：2019-11-25 00:00:00
abstract：BACKGROUND:This study aimed to examine the performance of the four risk of malignancy index (RMI) in discriminating borderline ovarian tumors (BOTs) and benign ovarian masses in daily clinical practice. METHODS:A total of 162 women with BOTs and 379 women with benign ovarian tumors diagnosed at the Second Affiliated H...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-019-0568-3
更新日期：2019-09-16 00:00:00
abstract：:AbstractThe original article [1] contains errors in Figs. 6 and 8. The corrected figures can be shown ahead. ...
journal_title：Journal of ovarian research
pub_type： 杂志文章,已发布勘误
doi：10.1186/s13048-019-0487-3
更新日期：2019-01-30 00:00:00
abstract：BACKGROUND:Mature cystic teratomas are usually found in the ovaries. They are bilateral in 10 to 15% of cases and multiple cystic teratomas may be present in one ovary. The aim of this study is to clarify if development of mature cystic teratomas of the ovaries in a single host is metachronous or due to autoimplant or ...
journal_title：Journal of ovarian research
pub_type： 杂志文章,评审
doi：10.1186/s13048-017-0313-8
更新日期：2017-03-14 00:00:00
abstract：BACKGROUND:Survivin is an inhibitor of apoptosis and a regulator of mitotic progression. TP53 protein is a negative transcriptional regulator of survivin. The aim of our study was to evaluate the clinical significance of survivin expression in advanced stages ovarian cancer with respect to the TP53 status. METHODS:Sur...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-4-20
更新日期：2011-11-10 00:00:00
abstract：BACKGROUND:Standard morphologic evaluation has been the most widely adopted approach to embryo selection, and remains the most common strategy.The objective of the study to determine the association between the morphologic grading and implantation rate of euploid blastocysts in single frozen-thawed embryo transfer (SET...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-021-00770-8
更新日期：2021-01-23 00:00:00
abstract：BACKGROUND:Ovarian cancer is the second most common gynecologic malignancy. As the primary imaging modality, computed tomography (CT) can provide staging information for preoperative planning and determination of surgical resectability. As a new three-dimensional postprocessing tool for CT images, cinematic rendering (...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-018-0461-5
更新日期：2018-09-26 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via the original article. ...
journal_title：Journal of ovarian research
pub_type： 已发布勘误
doi：10.1186/s13048-020-00733-5
更新日期：2020-11-12 00:00:00
abstract：BACKGROUND:Wnt-inducible signaling pathway protein 2 (WISP2) is a wnt1-induced signaling pathway protein 2. Although studies indicate that WISP2 may promote the development of various tumors, its role in ovarian cancer remains unclear. The objective of the current study was to analyze the effects of WISP2 on the prolif...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-020-00687-8
更新日期：2020-07-25 00:00:00
abstract：BACKGROUND:Hypertensive disorders of pregnancy are the most common causes of adverse maternal & perinatal outcomes. Such investigations in resource limited settings would help to have great design strategies in preventing maternal and perinatal morbidity and mortality. AIM:To determine management outcome and factor as...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-015-0135-5
更新日期：2015-03-15 00:00:00
abstract：UNLABELLED: BACKGROUND:To investigate the 3.0-Tesla (3 T) magnetic resonance imaging (MRI) characteristics of primary adnexal lesions for discriminating benign from malignant lesions. METHODS:One hundred thirty-nine patients with pathologically proven primary adnexal masses referred for 3 T MRI assessment preoperativ...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-5-33
更新日期：2012-11-14 00:00:00
abstract：BACKGROUND:This study was designed to investigate leptin levels in the fluid in ovarian endometriomas (OEs) and to compare the expression of leptin and its receptors (OBR) in ovarian tissue affected by endometrioma in infertile women to its expression in the normal ovarian tissue of fertile controls without endometrios...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-7-2
更新日期：2014-01-08 00:00:00
abstract：BACKGROUND:Because higher survival of follicles during the freezing/thawing procedure improves the quality of cryopreserved tissue reimplanted after oncological therapies, defining an optimal method for human ovarian tissue cryopreservation remains a major issue in this field. One option to improve the cryopreservation...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-016-0268-1
更新日期：2016-09-26 00:00:00
abstract：:Ovarian hyperstimulation syndrome (OHSS) is a serious complication of controlled ovarian hyperstimulation (COH). The syndrome almost always presents either after hCG administration in susceptible patients or during early pregnancy. Despite many years of clinical experience, there are no precise methods to completely p...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-6-77
更新日期：2013-11-05 00:00:00
abstract：:The Publisher and Editor regretfully retract this article ( Hou W, Guan J, Lu H, Dong Q, Han Y, Zhang R. The effects of dexamethasone on the proliferation and apoptosis of human ovarian cancer cells induced by paclitaxel. J Ovarian Res. 2014;7:89) because the peer-review process was inappropriately influenced and comp...
journal_title：Journal of ovarian research
pub_type： 撤回出版物
doi：10.1186/s13048-015-0144-4
更新日期：2015-03-26 00:00:00
abstract：BACKGROUND:Polycystic Ovary Syndrome (PCOS) is a widespread reproductive disorder characterized by a disruption of follicular growth and anovulatory infertility. In women with PCOS, follicular growth and ovulation can be induced by subcutaneous injections of low doses of follicle stimulating hormone (FSH). The aim of t...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-015-0192-9
更新日期：2015-10-06 00:00:00
abstract：BACKGROUND:Pelvic irradiation is essential for improving survival in women with pelvic malignancies despite inducing permanent ovarian damage. Ovarian transposition can be performed in premenopausal women in an attempt to preserve ovarian function. As uncertainty occurs over the proportion of women who are likely to be...
journal_title：Journal of ovarian research
pub_type： 杂志文章,meta分析,评审
doi：10.1186/1757-2215-7-69
更新日期：2014-06-25 00:00:00
abstract：:High-Grade Serous Ovarian Carcinoma (HGSOC) is the predominant histotype of epithelial ovarian cancer (EOC), characterized by advanced stage at diagnosis, frequent TP53 mutation, rapid progression, and high responsiveness to platinum-based-chemotherapy. To date, standard first-line-chemotherapy in advanced EOC include...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-016-0238-7
更新日期：2016-05-21 00:00:00
abstract：:Currently, the world is in the seventh month of the COVID-19 pandemic. Globally, infections with novel SARS-CoV-2 virus are continuously rising with mounting numbers of deaths. International and local public health responses, almost in synchrony, imposed restrictions to minimize spread of the virus, overload of health...
journal_title：Journal of ovarian research
pub_type： 杂志文章,评审
doi：10.1186/s13048-020-00737-1
更新日期：2020-11-27 00:00:00
abstract：BACKGROUND:Low adiponectin levels in polycystic ovarian syndrome (PCOS) have been largely attributed to obesity which is common among these patients. In addition, evidence also suggests that low adiponectin in PCOS may be related to insulin resistance (IR) in these women. However, studies on the role of adiponectin in ...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-7-18
更新日期：2014-02-07 00:00:00
abstract：:Following publication of the original article [1], the authors opted to correct the incorrect e-mail address of the corresponding author from 82-55-360-1850chungsu1982@gmail.com to chungsu1982@gmail.com , grant in the Acknowledgements section and Author details. Below are the updated version of the Acknowledgements an...
journal_title：Journal of ovarian research
pub_type： 已发布勘误
doi：10.1186/s13048-019-0540-2
更新日期：2019-07-23 00:00:00
abstract：BACKGROUND:This study was aimed to explore the role of long noncoding RNA C17orf91 and its potential mechanisms in ovarian cancer development. RESULTS:To assess its role in ovarian cancer, microarray datasets (GSE14407, GSE30587, and GSE17260) in Gene Expression Omnibus (GEO) were utilized to assess the expression and...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-016-0258-3
更新日期：2016-08-17 00:00:00
abstract：BACKGROUND:The polycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine condition characterized by hyperandrogenism, hyperinsulinemia, insulin resistance and chronic anovulation. Regulation and interaction of a multitude of genes required for follicular development are found to be altered in PCOS. Micr...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-6-36
更新日期：2013-05-15 00:00:00
abstract：BACKGROUND:This study aimed to identify the clinical and pathological characteristics and the possible prognostic factors for Chinese patients with early-stage ovarian endometrioid carcinoma. METHODS:The present study reviewed the medical records of patients who received initial treatment and a postoperative pathologi...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-017-0361-0
更新日期：2017-09-18 00:00:00
abstract：BACKGROUND:Resistance to apoptosis is a major problem in ovarian cancer (OC) and correlates with poor prognosis. Osteoprotegerin (OPG) is a soluble secreted factor that acts as a decoy receptor for receptor activator of NF-κB ligand (RANKL) and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). OPG has be...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/1757-2215-6-82
更新日期：2013-11-23 00:00:00
abstract：:The original article [1] contains errors in Fig. 3C, Results and Discussion. ...
journal_title：Journal of ovarian research
pub_type： 杂志文章,已发布勘误
doi：10.1186/s13048-020-00628-5
更新日期：2020-03-13 00:00:00
abstract：BACKGROUND:To investigate dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) for assessing histopathological and molecular biological features in induced rat epithelial ovarian carcinomas (EOCs). METHODS:7,12-dimethylbenz[A]anthracene (DMBA) was applied to induce EOCs in situ in 46 SD rats. Conventional MR...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-017-0362-z
更新日期：2017-09-26 00:00:00
abstract：:We have earlier reported the presence of very small embryonic-like stem cells (VSELs) in adult mouse uterus along with slightly bigger progenitors termed endometrial stem cells (EnSCs) and their regulation by ovarian hormones thus demonstrating a crucial role played by them during proliferation, differentiation and re...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-017-0324-5
更新日期：2017-04-24 00:00:00
abstract：BACKGROUND:Ovarian cancer is the leading cause of gynecological cancer-related mortality. The novel oncogene S100A10 has been reported to be involved in cancer cell proliferation, invasion and metastasis. The role of S100A10 in ovarian cancer has not been well studied and the effect of S100A10 on chemotherapy remains u...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-019-0592-3
更新日期：2019-11-18 00:00:00
abstract：BACKGROUND:We aimed to examine the expression of miR-1307 in chemosensitive and chemoresistant epithelial ovarian cancer tissues and cell lines and to analyze the clinicopathological significance of miR-1307 in ovarian cancer. METHODS:MicroRNA microarray was used to screen differentially expressed microRNAs between th...
journal_title：Journal of ovarian research
pub_type： 杂志文章
doi：10.1186/s13048-015-0143-5
更新日期：2015-04-09 00:00:00
