Abstract:
:Hypertension and arterial stiffening are independent predictors of cardiovascular mortality. Flavonoids may exert some vascular protection. We investigated the effects of black tea on blood pressure (BP) and wave reflections before and after fat load in hypertensives. According to a randomized, double-blind, controlled, cross-over design, 19 patients were assigned to consume black tea (129 mg flavonoids) or placebo twice a day for eight days (13 day wash-out period). Digital volume pulse and BP were measured before and 1, 2, 3 and 4 h after tea consumption. Measurements were performed in a fasted state and after a fat load. Compared to placebo, reflection index and stiffness index decreased after tea consumption (p<0.0001). Fat challenge increased wave reflection, which was counteracted by tea consumption (p<0.0001). Black tea decreased systolic and diastolic BP (-3.2 mmHg, p<0.005 and -2.6 mmHg, p<0.0001; respectively) and prevented BP increase after a fat load (p<0.0001). Black tea consumption lowers wave reflections and BP in the fasting state, and during the challenging haemodynamic conditions after a fat load in hypertensives. Considering lipemia-induced impairment of arterial function may occur frequently during the day, our findings suggest regular consumption of black tea may be relevant for cardiovascular protection.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Grassi D,Draijer R,Desideri G,Mulder T,Ferri Cdoi
10.3390/nu7021037subject
Has Abstractpub_date
2015-02-04 00:00:00pages
1037-51issue
2issn
2072-6643pii
nu7021037journal_volume
7pub_type
杂志文章,随机对照试验相关文献
Nutrients文献大全abstract::Osteoarthritis (OA) is characterized by progressive articular cartilage degradation. Although there have been significant advances in OA management, to date, there are no effective treatment options to modify progression of the disease. We believe these unmet needs could be bridged by nutrients from natural products. ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11020272
更新日期:2019-01-26 00:00:00
abstract::Dietary restraint is a commonly reported practice observed among young females. The practice remains controversial and can be interpreted as a beneficial self-regulating behavior or the opposite, an eating disorder that may have a detrimental effect on health. The aim of this short report was to investigate if dietary...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu8120796
更新日期:2016-12-19 00:00:00
abstract::Genistein has a preventive role against bone mass loss during menopause. However, experimental data in animal models of osteoporosis suggest an anti-osteoporotic potential for this isoflavone. We performed a post-hoc analysis of a previously published trial investigating the effects of genistein in postmenopausal wome...
journal_title:Nutrients
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.3390/nu9020179
更新日期:2017-02-22 00:00:00
abstract::Rheumatoid arthritis (RA) is a debilitating, chronic, inflammatory, autoimmune disease associated with cachexia. The substitutive therapy of gut hormone ghrelin has been pointed at as a potential countermeasure for the management of metabolic and inflammatory complications in RA. The recent discovery of liver-expresse...
journal_title:Nutrients
pub_type: 临床试验,杂志文章
doi:10.3390/nu12041006
更新日期:2020-04-06 00:00:00
abstract::Neurological dementias such as Alzheimer's disease and Lewy body dementia are thought to be caused in part by the formation and deposition of characteristic insoluble fibrils of polypeptides such as amyloid beta (Aβ), Tau, and/or α-synuclein (αSyn). In this context, it is critical to suppress and remove such aggregate...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12113480
更新日期:2020-11-13 00:00:00
abstract::Breakfast cereals are present on the market as different types and, in general, are one of the food categories in which voluntary information, such as nutrition or health claims (NHC) or gluten free (GF) declarations, have the largest distribution. The aims of the present study were to compare (i) the nutritional decl...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11112827
更新日期:2019-11-19 00:00:00
abstract::Preterm birth is an increasing worldwide problem. Prematurity is the second most common cause of death in children under 5 years of age. It is associated with a higher risk of several pathologies in the perinatal period and adulthood. Maternal milk, a complex fluid with several bioactive factors, is the best option fo...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu11061307
更新日期:2019-06-10 00:00:00
abstract::Selenium is an essential micronutrient that plays a crucial role in development and a wide variety of physiological processes including effect immune responses. The immune system relies on adequate dietary selenium intake and this nutrient exerts its biological effects mostly through its incorporation into selenoprote...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu10091203
更新日期:2018-09-01 00:00:00
abstract::The fatty acid compositions of plasma lipids and cell membranes of certain tissues are modified by dietary fatty acid composition. Furthermore, many other factors (age, sex, ethnicity, health status, genes, and gene × diet interactions) affect the fatty acid composition of cell membranes or plasma lipid compartments. ...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu10111785
更新日期:2018-11-16 00:00:00
abstract::Celiac disease (CD) is a chronic immune-mediated disorder, characterized by enhanced paracellular permeability across the intestinal epithelium. The complex system of intercellular junctions, including tight junctions (TJs) and adherens junctions (AJs), seals together the epithelial cells to form a continuous layer. T...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10111698
更新日期:2018-11-07 00:00:00
abstract::Food intake biomarkers (FIBs) can reflect the intake of specific foods or dietary patterns (DP). DP for successful aging (SA) has been widely studied. However, the relationship between SA and DP characterized by FIBs still needs further exploration as the candidate markers are scarce. Thus, 1H-nuclear magnetic resonan...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12102900
更新日期:2020-09-23 00:00:00
abstract::The mechanism by which high fat-diet induced obesity affects cardiac protein expression is unclear, and the extent to which this is modulated by prebiotic treatment is not known. These outcomes were assessed in rats initially fed a high-fat diet, then the top 40% weight gain group were randomly allocated to control (C...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12113404
更新日期:2020-11-05 00:00:00
abstract::This study sought to describe and compare adherence to the Mediterranean diet and consumption of local foods from the Huelva region among Spanish university women in relation to menstrual pain and other menstrual characteristics. This cross-sectional study included 311 health science students. The study variables were...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12061759
更新日期:2020-06-12 00:00:00
abstract::Obesity is characterized by an excessive body fat percentage (BF%). Animal and cell studies have shown benefits of vitamin A (VA) on BF% and lipid metabolism, but it is still controversial in humans. Furthermore, although some genetic variants may explain heterogeneity in VA plasma levels, their role in VA metabolic r...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12092588
更新日期:2020-08-26 00:00:00
abstract::Osteoarthritis (OA) has become one of the most common disabilities among elders, especially in females. Obesity and mechanical injuries caused by OA are attributed to joint loading, cartilage disintegration, and bone loss, as well as inflammation. Pharmacological and non-pharmacological treatments can be used for OA. ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10060686
更新日期:2018-05-28 00:00:00
abstract::A number of recent trials have demonstrated positive effects of dietary supplementation with the omega-3 polyunsaturated fatty acids (n-3 PUFAs), docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) on measures of cognitive function in healthy young and older adults. One potential mechanism by which EPA, and DHA...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu8020086
更新日期:2016-02-09 00:00:00
abstract::Docosahexaenoic acid (DHA), a long-chain omega-3 polyunsaturated fatty acid, has been used to treat a range of different conditions, including periodontal disease (PD) and inflammatory bowel disease (IBD). That DHA helps with these oral and gastrointestinal diseases in which inflammation and bacterial dysbiosis play k...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu5083299
更新日期:2013-08-19 00:00:00
abstract::This study was conducted to examine the nutrient intake status of cancer survivors. A total of 5224 cancer survivors, 19,926 non-cancer individuals without comorbidities (non-cancer I), and 20,622 non-cancer individuals with comorbidities, matched by age, gender, and recruitment center location were included in the an...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10020212
更新日期:2018-02-14 00:00:00
abstract::Standardized sex-specific cut-offs for sarcopenia in cirrhosis are needed to identify the risk of clinical complications and to discriminate the severity of sarcopenia. We aimed to compare clinical characteristics between patients with cirrhosis categorized according to the severity of sarcopenia. Computed tomography ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12113463
更新日期:2020-11-11 00:00:00
abstract::Human milk fortification is a routine clinical practice for feeding preterm infants. We hypothesized that donkey milk can be a suitable basis for developing an innovative human milk fortifier. Our randomized controlled single-blind clinical trial, named "Fortilat", evaluated the feeding tolerance, growth and clinical ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12123730
更新日期:2020-12-03 00:00:00
abstract::Vegetarian diets have been associated with atherosclerosis protection, with healthier atherosclerosis risk profiles, as well as lower prevalence of, and mortality from, ischemic heart disease and stroke. However, there are few data concerning the possible cardiovascular effects of a vegan diet (with no meat, dairy or ...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu6083259
更新日期:2014-08-19 00:00:00
abstract:BACKGROUND:Bifidobacterium represents an important early life microbiota member. Specific bifidobacterial components, exopolysaccharides (EPS), positively modulate host responses, with purified EPS also suggested to impact microbe-microbe interactions by acting as a nutrient substrate. Thus, we determined the longitudi...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12040948
更新日期:2020-03-29 00:00:00
abstract:BACKGROUND:The main goal of this study was to assess the acute effects of the intake of 9 and 11 mg/kg/ body mass (b.m.) of caffeine (CAF) on maximal strength and muscle endurance in athletes habituated to caffeine. METHODS:The study included 16 healthy strength-trained male athletes (age = 24.2 ± 4.2 years, body mass...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11081912
更新日期:2019-08-15 00:00:00
abstract::Dietary supplement use may modify the risk of periodontal disease but effects on wound healing after periodontal procedures are less clear. This study characterized dietary supplement use by male and female patients (n = 376) attending a periodontal clinic-information that is essential for evidence-based intervention ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu5041110
更新日期:2013-04-02 00:00:00
abstract::Infancy and childhood are periods of physical and cognitive development that are vulnerable to disruption by dehydration; however, the effects of dehydration on cognitive development during the periods have not yet been fully elucidated. Thus, the present study used a murine model to examine the effects of sustained d...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12030670
更新日期:2020-02-29 00:00:00
abstract::Consumer demand for plant protein-based products is high and expected to grow considerably in the next decade. Factors contributing to the rise in popularity of plant proteins include: (1) potential health benefits associated with increased intake of plant-based diets; (2) consumer concerns regarding adverse health ef...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12123704
更新日期:2020-11-30 00:00:00
abstract::Necrotizing enterocolitis (NEC) remains a significant cause of morbidity and mortality in preterm infants. Formula feeding is a risk factor for NEC and osmolality, which is increased by the fortification that is required for adequate growth of the infant, has been suggested as a potential cause. Our laboratory has sho...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12040900
更新日期:2020-03-26 00:00:00
abstract::The effect of the betaine: homocysteine methyltransferase BHMT c.716G>A (G: guanosine; A: adenosine) single nucleotide polymorphism (SNP) on the BHMT pathway is unknown during pregnancy. We hypothesised that it impairs betaine to dimethylglycine conversion and that folate status modifies its effect. We studied 612 wom...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu8100621
更新日期:2016-10-09 00:00:00
abstract::Dietary fructose has been linked to an increased post-prandial triglyceride (TG) level; which is an established independent risk factor for cardiovascular disease. Although much research has focused on the effects of fructose consumption on liver-derived very-low density lipoprotein (VLDL); emerging evidence also sugg...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu9040349
更新日期:2017-04-01 00:00:00
abstract::Members of the genus Curcuma L. have been used in traditional medicine for centuries for treating gastrointestinal disorders, pain, inflammatory conditions, wounds, and for cancer prevention and antiaging, among others. Many of the biological activities of Curcuma species can be attributed to nonvolatile curcuminoids,...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu10091196
更新日期:2018-09-01 00:00:00