Incidence of cervical dysplasia and cervical cancer in women living with HIV in Denmark: comparison with the general population.

abstract：INTRODUCTION:T cell immunoglobulin and mucin domain (Tim) 3 and programmed death 1 (PD-1) are co-inhibitory receptors involved in the so-called T cell exhaustion, and in vivo blockade of these molecules restores T cell dysfunction. High expression of Tim-3 and PD-1 is induced after chronic antigen-specific stimulation ...

journal_title：Journal of the International AIDS Society

authors： Sada-Ovalle I,Ocaña-Guzman R,Pérez-Patrigeón S,Chávez-Galán L,Sierra-Madero J,Torre-Bouscoulet L,Addo MM

更新日期：2015-10-19 00:00:00

abstract：INTRODUCTION:Critical technological advances have yielded a toolkit of HIV prevention strategies. This literature review sought to provide contextual and historical reflection needed to bridge the conceptual gap between clinical efficacy and community effectiveness (i.e. knowledge and usage) of existing HIV prevention ...

journal_title：Journal of the International AIDS Society

authors： Parker RG,Perez-Brumer A,Garcia J,Gavigan K,Ramirez A,Milnor J,Terto V Jr

更新日期：2016-09-30 00:00:00

abstract：INTRODUCTION:Outbreaks of hepatitis C virus (HCV) infections among HIV-positive men who have sex with men (MSM) have been observed globally. Using a multi-modelling approach we estimate the time and number of direct-acting antiviral treatment courses required to achieve an 80% reduction in HCV prevalence among HIV-posi...

journal_title：Journal of the International AIDS Society

authors： Scott N,Stoové M,Wilson DP,Keiser O,El-Hayek C,Doyle J,Hellard M

更新日期：2018-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.7448/IAS.20.01/21317.]. ...

journal_title：Journal of the International AIDS Society

authors：

更新日期：2017-06-02 00:00:00

abstract：INTRODUCTION:To be used most effectively, pre-exposure prophylaxis (PrEP) should be prioritized to those at high risk of acquisition and would ideally be aligned with time periods of increased exposure. Identifying such time periods is not always straightforward, however. Gaza Province in southern Mozambique is charact...

journal_title：Journal of the International AIDS Society

authors： Cremin I,Morales F,Jewell BL,O'Reilly KR,Hallett TB

更新日期：2015-07-20 00:00:00

abstract：INTRODUCTION:Antiretroviral treatment (ART) has been scaled up over the last decade but compared to adults, children living with HIV are less likely to receive ART. Moreover, children and adolescents are more vulnerable than adults to virological failure (VF) and emergence of drug resistance. In this study we determine...

journal_title：Journal of the International AIDS Society

authors： Salou M,Dagnra AY,Butel C,Vidal N,Serrano L,Takassi E,Konou AA,Houndenou S,Dapam N,Singo-Tokofaï A,Pitche P,Atakouma Y,Prince-David M,Delaporte E,Peeters M

更新日期：2016-04-27 00:00:00

abstract：:While there has been remarkable progress in understanding the biology of HIV-1 and its recognition by the human immune system, we have not yet developed an efficacious HIV-1 vaccine. Vaccine challenges include the genetic diversity and mutability of HIV-1 which create a plethora of constantly changing antigens, the st...

journal_title：Journal of the International AIDS Society

authors： Kwong PD,Mascola JR,Nabel GJ

更新日期：2012-07-05 00:00:00

abstract：INTRODUCTION:As adolescents transition from childhood to adulthood, they experience major physical, social and psychological changes, and are at heightened risk for developing mental health conditions and engaging in health-related risk behaviours. For adolescents living with HIV (ALHIV), these risks may be even more p...

journal_title：Journal of the International AIDS Society

authors： Laurenzi CA,Skeen S,Gordon S,Akin-Olugbade O,Abrahams N,Bradshaw M,Brand A,du Toit S,Melendez-Torres GJ,Tomlinson M,Servili C,Dua T,Ross DA

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:Women living with HIV are required to transition into the prevention of mother-to-child transmission of HIV (PMTCT) services when they become pregnant and back to ART services after delivery. Transition can be a vulnerable time when many women are lost from HIV care yet there is little guidance on the opti...

journal_title：Journal of the International AIDS Society

authors： Phillips TK,Teasdale CA,Geller A,Ng'eno B,Mogoba P,Modi S,Abrams EJ

更新日期：2021-01-01 00:00:00

abstract：INTRODUCTION:Several factors such as duration of infection, age, male gender, consumption of alcohol, HIV infection and low CD4 count have been associated with fibrosis progression rate. However, it is relatively scarce, the knowledge about the liver fibrosis progression rate in HIV-infected patients with undetectable ...

journal_title：Journal of the International AIDS Society

authors： Perez-Martinez L,Sanjoaquin I,Rivero M,Gil-Pérez D,Letona S,Olaiz CI,Arazo P,Blanco JR

更新日期：2014-11-02 00:00:00

abstract：BACKGROUND:Traditional medication adherence measures do not account for the pharmacokinetic (PK) properties of the drugs, potentially misrepresenting true therapeutic exposure. METHODS:In a population of HIV-infected Kenyan children on antiretroviral therapy including nevirapine (NVP), we used a one-compartment model ...

journal_title：Journal of the International AIDS Society

authors： Tu W,Nyandiko WM,Liu H,Slaven JE,Scanlon ML,Ayaya SO,Vreeman RC

更新日期：2017-06-15 00:00:00

abstract：:Eastern Europe and Central Asia have the largest drug epidemic globally and the fastest and still expanding HIV epidemic. The Russian Federation and Ukraine together account for over 90% of the reported AIDS cases in the region. If small in absolute numbers, the epidemics are however significant in prevalence rate in ...

journal_title：Journal of the International AIDS Society

authors： Kazatchkine M

更新日期：2014-11-02 00:00:00

abstract：: The HIV/AIDS epidemic continues to be a major issue facing Botswana, with overall adult HIV prevalence estimated to be 25.7 percent in 2007. This paper estimates the cost and impact of the draft Ministry of Health male circumcision strategy using the UNAIDS/WHO Decision-Makers' Programme Planning Tool (DMPPT). Demogr...

journal_title：Journal of the International AIDS Society

authors： Bollinger LA,Stover J,Musuka G,Fidzani B,Moeti T,Busang L

更新日期：2009-05-27 00:00:00

abstract：INTRODUCTION:Gonorrhoea and chlamydia cases have been rising among gay, bisexual and other men who have sex with men (MSM) over the last decade. The majority of cases are extragenital and occur at the oropharynx and anorectum. The aim of this narrative review was to review the risk factors and mode of transmission for ...

journal_title：Journal of the International AIDS Society

authors： Chow EP,Fairley CK

更新日期：2019-08-01 00:00:00

abstract：INTRODUCTION:HIV-1-associated CD4+ T-cell depletion is a consequence of uninfected cell death. Nef is one of the viral factors that trigger apoptosis on bystander cells, though the plasma Nef levels do not correlate with Th lymphocytes counts. The aim of our study was to evaluate whether anti-Nef antibodies were involv...

journal_title：Journal of the International AIDS Society

authors： Corró G,Crudeli CM,Rocco CA,Marino SA,Sen L

更新日期：2014-02-14 00:00:00

abstract：INTRODUCTION:Routes of transmission and reasons for HIV testing are important epidemiologic data to analyze the epidemic and to tailor the response to AIDS. The aim of this study was to analyze reasons for testing and transmission ways of HIV among recently diagnosed HIV patients registered in the multicenter HIV-TR co...

journal_title：Journal of the International AIDS Society

authors： Dokuzoguz B,Korten V,Gökengin D,Fincanci M,Yildirmak T,Kes UN,Tasdelen Fisgin N,Inan D,Eraksoy H,Akalin H

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Despite recent advances in the management of HIV infection and increased access to treatment, prevention, care and support, the HIV/AIDS epidemic continues to be a major global health problem, with sub-Saharan Africa suffering by far the greatest humanitarian, demographic and socio-economic burden of the e...

journal_title：Journal of the International AIDS Society

authors： Divaris K,Newman J,Hemingway-Foday J,Akam W,Balimba A,Dusengamungu C,Kalenga L,Mbaya M,Molu BM,Mugisha V,Mukumbi H,Mushingantahe J,Nash D,Niyongabo T,Atibu J,Azinyue I,Kiumbu M,Woelk G

更新日期：2012-11-21 00:00:00

abstract：INTRODUCTION:Modern combined antiretroviral therapies (cART) allow to effectively suppress HIV-1 viral load, with the 90% virologic success rate, meeting the WHO target in most clinical settings. The aim of this study was to analyse antiretroviral treatment efficacy in Poland and to identify variables associated with v...

journal_title：Journal of the International AIDS Society

authors： Parczewski M,Siwak E,Leszczyszyn-Pynka M,Cielniak I,Burkacka E,Pulik P,Witor A,Muller K,Zasik E,Grzeszczuk A,Jankowska M,Lemańska M,Olczak A,Grąbczewska E,Szymczak A,Gąsiorowski J,Szetela B,Bociąga-Jasik M,Skwara P,

更新日期：2017-07-17 00:00:00

abstract：BACKGROUND:The majority of new HIV infections are acquired through heterosexual transmission. There is urgent need for prevention methods to compliment behavior change and condom use. Topical microbicide represent a potential strategy for reduction of HIV transmission in women. METHODS:Monthly Colposcopy evaluations w...

journal_title：Journal of the International AIDS Society

authors： Chirenje ZM,Mâsse BR,Maslankowski LA,Ramjee G,Coletti AS,Tembo TN,Magure TM,Soto-Torres L,Kelly C,Hillier S,Karim A

更新日期：2012-08-27 00:00:00

abstract：INTRODUCTION:A key objective of combined antiretroviral therapy (cART) is to reach and maintain high CD4 cell counts to provide long-term protection against AIDS-defining opportunistic infections and malignancies, as well as other comorbidities. However, a high proportion of patients present late for care. Our objectiv...

journal_title：Journal of the International AIDS Society

authors： Costagliola D,Lacombe JM,Ghosn J,Delaugerre C,Pialoux G,Cuzin L,Launay O,Ménard A,de Truchis P,Mary-Krause M,Weiss L,Delfraissy JF

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Numerous barriers to optimal uptake of prevention of mother to child transmission (PMTCT) services occur at community level (i.e., outside the healthcare setting). To achieve elimination of paediatric HIV, therefore, interventions must also work within communities to address these barriers and increase ser...

journal_title：Journal of the International AIDS Society

authors： Busza J,Walker D,Hairston A,Gable A,Pitter C,Lee S,Katirayi L,Simiyu R,Mpofu D

更新日期：2012-07-11 00:00:00

abstract：INTRODUCTION:HIV prevalence is declining in key populations in Armenia including in people who inject drugs (PWID), men who have sex with men, prison inmates, and female sex workers (FSWs); however, prevalence is increasing among Armenians who seasonally migrate to work in countries with higher HIV prevalence, primaril...

journal_title：Journal of the International AIDS Society

authors： Kelly SL,Shattock AJ,Kerr CC,Stuart RM,Papoyan A,Grigoryan T,Hovhannisyan R,Grigoryan S,Benedikt C,Wilson DP

更新日期：2016-06-07 00:00:00

abstract：INTRODUCTION:Most clinical trials for new antiretroviral (ARV) agents are conducted among narrowly defined adult populations. Only after safety and efficacy have been clearly demonstrated among adults living with HIV are trials including adolescents, children and infants conducted. This approach contributes to signific...

journal_title：Journal of the International AIDS Society

authors： Rojo P,Carpenter D,Venter F,Turkova A,Penazzato M

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:Decentralization of HIV care for children has been recommended to improve paediatric outcomes by making antiretroviral treatment (ART) more accessible. We documented outcomes of children transferred after initiating ART at a large tertiary hospital in the Eastern Cape of South Africa. METHODS:Electronic m...

journal_title：Journal of the International AIDS Society

authors： Teasdale CA,Sogaula N,Yuengling KA,Peters ZJ,Mutiti A,Pepeta L,Abrams EJ

更新日期：2017-06-28 00:00:00

abstract：INTRODUCTION:Switching to a rilpivirine, tenofovir and emtricitabine (RTE) single-tablet regimen (STR) has been evaluated in a limited number of virologically suppressed patients. The aim of this study was to describe clinical outcomes in HIV-positive patients switched from a suppressive antiretroviral regimen to RTE S...

journal_title：Journal of the International AIDS Society

authors： Gianotti N,Poli A,Nozza S,Spagnuolo V,Tambussi G,Bossolasco S,Cinque P,Maillard M,Cernuschi M,Galli L,Lazzarin A,Castagna A

更新日期：2015-07-30 00:00:00

abstract：BACKGROUND:The aim of our study was to assess the extent of late presentation for HIV care in Northern Greece during the period 2000 to 2010 and to explore correlations aiming to provide guidance for future interventions. METHODS:HIV-positive patients with no prior history of HIV care at presentation and with a CD4 T ...

journal_title：Journal of the International AIDS Society

authors： Metallidis S,Pilalas D,Skoura L,Haidich AB,Tsachouridou O,Papaioannou M,Chrysanthidis T,Bakaimi I,Antoniadou ZA,Margariti A,Malisiovas N,Nikolaidis P

更新日期：2012-10-11 00:00:00

abstract：INTRODUCTION:Qualitative research on antiretroviral therapy (ART) adherence interventions can provide a deeper understanding of intervention facilitators and barriers. This systematic review aims to synthesize qualitative evidence of interventions for improving ART adherence and to inform patient-centred policymaking. ...

journal_title：Journal of the International AIDS Society

authors： Ma Q,Tso LS,Rich ZC,Hall BJ,Beanland R,Li H,Lackey M,Hu F,Cai W,Doherty M,Tucker JD

更新日期：2016-10-17 00:00:00

abstract：INTRODUCTION:In response to the increasing burden of HIV, the Ugandan government has employed different service delivery models since 2004 that aim to reduce costs and remove barriers to accessing HIV care. These models include community-based approaches to delivering antiretroviral therapy (ART) and delegating tasks t...

journal_title：Journal of the International AIDS Society

authors： Vu L,Waliggo S,Zieman B,Jani N,Buzaalirwa L,Okoboi S,Okal J,Borse NN,Kalibala S

更新日期：2016-07-20 00:00:00

abstract：INTRODUCTION:Rilpivirine (RPV) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) that was recently approved for the treatment of antiretroviral-naïve individuals with HIV-1 viral load of <100,000 copies/ml. As transmission of the drug resistance mutations to this NNRTI may affect treatment o...

journal_title：Journal of the International AIDS Society

authors： Parczewski M,Urbańska A,Maciejewska K,Witak-Jȩdra M,Leszczyszyn-Pynka M

更新日期：2014-04-17 00:00:00

abstract：INTRODUCTION:In 2014 the Joint United Nations Programme on HIV/AIDS defined the ambitious 90-90-90 targets for 2020, in which 90% of people living with HIV must be diagnosed, 90% of those diagnosed should be on sustained therapy and 90% of those on therapy should have an undetectable viral load. Children are considered...

journal_title：Journal of the International AIDS Society

authors： Rabie H,Frigati L,Hesseling AC,Garcia-Prats AJ

更新日期：2015-12-02 00:00:00