The cost and impact of male circumcision on HIV/AIDS in Botswana.

abstract：INTRODUCTION:In 2013, the World Health Organization (WHO) recommended initiating combination ART (cART) in all adults with HIV and CD4+ lymphocyte counts (CD4) <500 cells/mm3 . In 2015, this was updated to recommend cART initiation in all patients with HIV, regardless of CD4 count. Implementation of these guidelines in...

journal_title：Journal of the International AIDS Society

authors： Crabtree-Ramírez BE,Caro-Vega Y,Belaunzarán-Zamudio PF,Shepherd BE,Rebeiro PF,Veloso V,Cortes CP,Padgett D,Gotuzzo E,Sierra-Madero J,McGowan CC,Person AK,Caribbean, Central, South America Network for HIV Epidemiology (CCASAnet).

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Injection drug use remains a major risk factor for HIV transmission in Georgia. The study aims to characterize the prevalence of HIV among injection drug users in Georgia. METHODS:A cross-sectional, anonymous bio-behavioural survey to assess knowledge and behaviour in injection drug users in combination wit...

journal_title：Journal of the International AIDS Society

authors： Chikovani I,Goguadze K,Ranade S,Wertlieb M,Rukhadze N,Gotsadze G

更新日期：2011-02-15 00:00:00

abstract：:While there has been remarkable progress in understanding the biology of HIV-1 and its recognition by the human immune system, we have not yet developed an efficacious HIV-1 vaccine. Vaccine challenges include the genetic diversity and mutability of HIV-1 which create a plethora of constantly changing antigens, the st...

journal_title：Journal of the International AIDS Society

authors： Kwong PD,Mascola JR,Nabel GJ

更新日期：2012-07-05 00:00:00

abstract：INTRODUCTION:Antiretroviral (ARV)-based pre-exposure prophylaxis (PrEP) is a promising new HIV prevention strategy. However, variable levels of adherence have yielded mixed results across several PrEP trials and populations. It is not clear how taking ARV - traditionally used for HIV treatment - is perceived and how th...

journal_title：Journal of the International AIDS Society

authors： van der Straten A,Stadler J,Luecke E,Laborde N,Hartmann M,Montgomery ET,VOICE-C Study Team.

更新日期：2014-09-08 00:00:00

abstract：INTRODUCTION:Worldwide, 71 million people are infected with hepatitis C virus (HCV), which, without treatment, can lead to liver failure or hepatocellular carcinoma. HCV co-infection increases liver- and AIDS-related morbidity and mortality among HIV-positive people, despite ART. A 12-week course of HCV direct-acting a...

journal_title：Journal of the International AIDS Society

authors： Grillon C,Krishtel PR,Mellouk O,Basenko A,Freeman J,Mendão L,Andrieux-Meyer I,Morin S

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:The majority of new HIV infections occur through mucosal transmission. The availability of readily applicable and accessible platforms for anti-retroviral (ARV) delivery is critical for the prevention of HIV acquisition through sexual transmission in both women and men. There is a compelling need for devel...

journal_title：Journal of the International AIDS Society

authors： Crakes KR,Herrera C,Morgan JL,Olstad K,Hessell AJ,Ziprin P,LiWang PJ,Dandekar S

更新日期：2020-10-01 00:00:00

abstract：INTRODUCTION:Preventive therapy is essential for reducing tuberculosis (TB) burden among people living with HIV (PLWH) in high-burden settings. Short-course preventive therapy regimens, such as three-month weekly rifapentine and isoniazid (3HP) and one-month daily rifapentine and isoniazid (1HP), may help facilitate up...

journal_title：Journal of the International AIDS Society

authors： Ferguson O,Jo Y,Pennington J,Johnson K,Chaisson RE,Churchyard G,Dowdy D

更新日期：2020-10-01 00:00:00

abstract：INTRODUCTION:Every year, approximately 260,000 children are infected with HIV in low- and middle-income countries. The timely initiation and high level of maintenance of antiretroviral therapy (ART) are crucial to reducing the suffering of HIV-positive children. We need to develop a better understanding of the backgrou...

journal_title：Journal of the International AIDS Society

authors： Kikuchi K,Poudel KC,Muganda J,Sato T,Mutabazi V,Muhayimpundu R,Majyambere A,Nyonsenga SP,Sase E,Jimba M

更新日期：2014-12-03 00:00:00

abstract：INTRODUCTION:Virtually no African country provides HIV prevention services in sex work settings with an adequate scale and intensity. Uncertainty remains about the optimal set of interventions and mode of delivery. METHODS:We systematically reviewed studies reporting interventions for reducing HIV transmission among f...

journal_title：Journal of the International AIDS Society

authors： Chersich MF,Luchters S,Ntaganira I,Gerbase A,Lo YR,Scorgie F,Steen R

更新日期：2013-03-04 00:00:00

abstract：INTRODUCTION:Vaginal tenofovir (TFV) 1% gel may reduce incident HIV-1 and herpes simplex virus 2 infection. Pregnancy may increase risk of HIV acquisition, and incident HIV in pregnancy potentiates perinatal HIV transmission. Our objective was to investigate the safety and pharmacokinetics of seven days of TFV 1% vagin...

journal_title：Journal of the International AIDS Society

authors： Beigi RH,Noguchi LM,Montgomery E,Biggio J,Hendrix CW,Marzinke MA,Dai JY,Pan J,Kunjara Na Ayudhya R,Schwartz JL,Isaacs K,Piper JM,Watts DH

更新日期：2016-09-21 00:00:00

abstract：INTRODUCTION:Lopinavir/ritonavir-based antiretroviral therapy (ART) is recommended for all HIV-infected children less than three years. However, little is known about its field implementation and effectiveness in West Africa. We assessed the 12-month response to lopinavir/ritonavir-based antiretroviral therapy in a coh...

journal_title：Journal of the International AIDS Society

authors： Amani-Bosse C,Dahourou DL,Malateste K,Amorissani-Folquet M,Coulibaly M,Dattez S,Emieme A,Barry M,Rouzioux C,N'gbeche S,Yonaba C,Timité-Konan M,Mea V,Ouédraogo S,Blanche S,Meda N,Seguin-Devaux C,Leroy V

更新日期：2017-04-25 00:00:00

abstract：INTRODUCTION:The long-term effects of an intensified induction regimen are unknown. In this pilot, randomized, prospective study we evaluate the effect of a short-term four-drugs induction regimen in patients with high baseline viral load. METHODS:Naive patients with HIV-RNA>100.000 copies/ml receiving TDF+FTC+EFV+RAL...

journal_title：Journal of the International AIDS Society

authors： Maggiolo F,Masini G,Astuti N,Di Filippo E,Benatti S,Valenti D,Callegaro AP,Rizzi M

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Countries in the West and Central African regions struggle to offer quality HIV care at scale, despite HIV prevalence being relatively low. In these challenging operating environments, basic health care needs are multiple, systems are highly fragile and conflict disrupts health care. Médecins Sans Frontièr...

journal_title：Journal of the International AIDS Society

authors： Ssonko C,Gonzalez L,Mesic A,da Fonseca MS,Achar J,Safar N,Martin B,Wong S,Casas EC

更新日期：2017-07-21 00:00:00

abstract：BACKGROUND:The majority of new HIV infections are acquired through heterosexual transmission. There is urgent need for prevention methods to compliment behavior change and condom use. Topical microbicide represent a potential strategy for reduction of HIV transmission in women. METHODS:Monthly Colposcopy evaluations w...

journal_title：Journal of the International AIDS Society

authors： Chirenje ZM,Mâsse BR,Maslankowski LA,Ramjee G,Coletti AS,Tembo TN,Magure TM,Soto-Torres L,Kelly C,Hillier S,Karim A

更新日期：2012-08-27 00:00:00

abstract：INTRODUCTION:The World Health Organization targets for hepatitis C virus (HCV) elimination include a 90% reduction in new infections by 2030. Our objective is to review the modelling evidence and cost data surrounding feasibility of HCV elimination among people living with HIV (PLWH), and identify likely components for...

journal_title：Journal of the International AIDS Society

authors： Martin NK,Boerekamps A,Hill AM,Rijnders BJA

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:Globally, young gay, bisexual and other men who have sex with men (gbMSM) continue to experience disproportionately high rates of HIV and other sexually transmitted and blood-borne infections (STBBIs). As such, there are strong public health imperatives to evaluate innovative prevention, treatment and care...

journal_title：Journal of the International AIDS Society

authors： Knight R,Karamouzian M,Salway T,Gilbert M,Shoveller J

更新日期：2017-11-01 00:00:00

abstract：INTRODUCTION:HIV-1-associated CD4+ T-cell depletion is a consequence of uninfected cell death. Nef is one of the viral factors that trigger apoptosis on bystander cells, though the plasma Nef levels do not correlate with Th lymphocytes counts. The aim of our study was to evaluate whether anti-Nef antibodies were involv...

journal_title：Journal of the International AIDS Society

authors： Corró G,Crudeli CM,Rocco CA,Marino SA,Sen L

更新日期：2014-02-14 00:00:00

abstract：INTRODUCTION:While there is a global consensus on monitoring Human Immunodeficiency Virus (HIV) treatment progress, there has been less attention to the degree of consistency of the measurement of HIV prevention programmes-and the global prevention response is not on-track to achieve 2020 goals. In this paper, we asses...

journal_title：Journal of the International AIDS Society

authors： Sekimitsu S,DePasse J,Morrison M,Mahy M,Rice B,Earle K,Daley K,Larson J,Carter A,Garnett GP,Holmes CB

更新日期：2020-12-01 00:00:00

abstract：INTRODUCTION:Men who have sex with men (MSM) and transgender women (TGW) are two key populations (KPs) in Thailand at high risk for HIV. Uptake and scale-up of pre-exposure prophylaxis (PrEP) among them has been slow. We used data from Princess PrEP, Thailand's largest KP-led PrEP programme, to operationalize PrEP serv...

journal_title：Journal of the International AIDS Society

authors： Ramautarsing RA,Meksena R,Sungsing T,Chinbunchorn T,Sangprasert T,Fungfoosri O,Meekrua D,Sumalu S,Pasansai T,Bunainso W,Wongsri T,Mainoy N,Colby D,Avery M,Mills S,Vannakit R,Phanuphak P,Phanuphak N

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:HIV testing is an essential prerequisite for accessing treatment with antiretroviral therapy or prevention using pre-exposure prophylaxis. Internet distribution of HIV self-tests is a novel approach, and data on the programmatic cost of this approach are limited. We analyse the costs and cost-effectiveness...

journal_title：Journal of the International AIDS Society

authors： Shrestha RK,Chavez PR,Noble M,Sansom SL,Sullivan PS,Mermin JH,MacGowan RJ

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Qualitative research on antiretroviral therapy (ART) adherence interventions can provide a deeper understanding of intervention facilitators and barriers. This systematic review aims to synthesize qualitative evidence of interventions for improving ART adherence and to inform patient-centred policymaking. ...

journal_title：Journal of the International AIDS Society

authors： Ma Q,Tso LS,Rich ZC,Hall BJ,Beanland R,Li H,Lackey M,Hu F,Cai W,Doherty M,Tucker JD

更新日期：2016-10-17 00:00:00

abstract：:Improved knowledge, better programmes and policies, effective treatment and other scientific developments have reduced levels of new HIV infections globally. Evidence shows that programmes that prevent HIV among sex workers and their clients are most successful when all aspects of vulnerability are addressed and when ...

journal_title：Journal of the International AIDS Society

authors： Overs C,Loff B

更新日期：2013-08-29 00:00:00

abstract：:Family-based interventions with children who are affected by HIV and AIDS are not well established. The Collaborative HIV Prevention and Adolescent Mental Health Program (CHAMP) represents one of the few evidence-based interventions tested in low-income contexts in the US, Caribbean and South Africa. This paper provid...

journal_title：Journal of the International AIDS Society

authors： Bhana A,McKay MM,Mellins C,Petersen I,Bell C

更新日期：2010-06-23 00:00:00

abstract：INTRODUCTION:Despite recent advances in the management of HIV infection and increased access to treatment, prevention, care and support, the HIV/AIDS epidemic continues to be a major global health problem, with sub-Saharan Africa suffering by far the greatest humanitarian, demographic and socio-economic burden of the e...

journal_title：Journal of the International AIDS Society

authors： Divaris K,Newman J,Hemingway-Foday J,Akam W,Balimba A,Dusengamungu C,Kalenga L,Mbaya M,Molu BM,Mugisha V,Mukumbi H,Mushingantahe J,Nash D,Niyongabo T,Atibu J,Azinyue I,Kiumbu M,Woelk G

更新日期：2012-11-21 00:00:00

abstract：INTRODUCTION:Achieving UNAIDS 90-90-90 targets is a crucial step towards ending the AIDS epidemic. Many countries have published estimates of care cascades, although often with methodological limitations. We describe an approach that used the national HIV registry as a starting-point to determine the HIV care cascade a...

journal_title：Journal of the International AIDS Society

authors： Ho ZJM,Huang F,Wong CS,Chua L,Ma S,Chen MI,Lee VJ

更新日期：2019-07-01 00:00:00

abstract：INTRODUCTION:Pre-treatment HIV drug resistance (PDR) is an increasing problem in sub-Saharan Africa. Children are an especially vulnerable population to develop PDR given that paediatric second-line treatment options are limited. Although monitoring of PDR is important, data on the paediatric prevalence in sub-Saharan ...

journal_title：Journal of the International AIDS Society

authors： Boerma RS,Boender TS,Sigaloff KC,Rinke de Wit TF,van Hensbroek MB,Ndembi N,Adeyemo T,Temiye EO,Osibogun A,Ondoa P,Calis JC,Akanmu AS

更新日期：2016-11-10 00:00:00

abstract：INTRODUCTION:HIV incidence remains high among young women in sub-Saharan Africa in spite of scale-up of HIV testing, behavioural interventions, antiretroviral treatment and medical male circumcision. There is a critical need to critique past approaches and learn about the most effective implementation of evidence-based...

journal_title：Journal of the International AIDS Society

authors： Celum CL,Delany-Moretlwe S,McConnell M,van Rooyen H,Bekker LG,Kurth A,Bukusi E,Desmond C,Morton J,Baeten JM

更新日期：2015-07-20 00:00:00

abstract：INTRODUCTION:For many women living with HIV (WLWH), the disclosure of positive status can lead to either an extension of former violence or new conflict specifically associated with HIV status disclosure. This study aims to explore the following about WLWH: 1. the women's experiences of intimate partner violence (IPV) ...

journal_title：Journal of the International AIDS Society

authors： Colombini M,James C,Ndwiga C,Integra team.,Mayhew SH

更新日期：2016-03-31 00:00:00

abstract：INTRODUCTION:Antiretroviral treatment (ART) has been scaled up over the last decade but compared to adults, children living with HIV are less likely to receive ART. Moreover, children and adolescents are more vulnerable than adults to virological failure (VF) and emergence of drug resistance. In this study we determine...

journal_title：Journal of the International AIDS Society

authors： Salou M,Dagnra AY,Butel C,Vidal N,Serrano L,Takassi E,Konou AA,Houndenou S,Dapam N,Singo-Tokofaï A,Pitche P,Atakouma Y,Prince-David M,Delaporte E,Peeters M

更新日期：2016-04-27 00:00:00

abstract：INTRODUCTION:Poor access of lesbian, gay, bisexual and transgender (LGBT) people to healthcare providers with clinical and cultural competency contributes to health inequalities between heterosexual/cisgender and LGBT people. This systematic review assesses the effect of educational curricula and training for healthcar...

journal_title：Journal of the International AIDS Society

authors： Sekoni AO,Gale NK,Manga-Atangana B,Bhadhuri A,Jolly K

更新日期：2017-07-19 00:00:00