The tide cannot be turned without us: sex workers and the global response to HIV.

abstract：BACKGROUND:Diagnosis of primary HIV infection (PHI) has important clinical and public health implications. HAART initiation at this stage remains controversial. METHODS:Our objective was to identify predictors of disease progression among Argentinean seroconverters during the first year of infection, within a multicen...

journal_title：Journal of the International AIDS Society

authors： Socías ME,Sued O,Laufer N,Lázaro ME,Mingrone H,Pryluka D,Remondegui C,Figueroa MI,Cesar C,Gun A,Turk G,Bouzas MB,Kavasery R,Krolewiecki A,Pérez H,Salomón H,Cahn P,Grupo Argentino de Seroconversión Study Group.

更新日期：2011-08-10 00:00:00

abstract：INTRODUCTION:This descriptive, non-interventional study on HIV-1-infected patients treated with DRV/r in the usual clinical setting, with a single-arm prospective observational design, collected data on utilization of darunavir/ritonavir (DRV/r) under the conditions described in marketing authorization in usual clinica...

journal_title：Journal of the International AIDS Society

authors： Antinori A,Borderi M,Cauda R,Bini T,Chirianni A,Squillace N,Mancusi D,Termini R

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:The World Health Organization targets for hepatitis C virus (HCV) elimination include a 90% reduction in new infections by 2030. Our objective is to review the modelling evidence and cost data surrounding feasibility of HCV elimination among people living with HIV (PLWH), and identify likely components for...

journal_title：Journal of the International AIDS Society

authors： Martin NK,Boerekamps A,Hill AM,Rijnders BJA

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:Every year, approximately 260,000 children are infected with HIV in low- and middle-income countries. The timely initiation and high level of maintenance of antiretroviral therapy (ART) are crucial to reducing the suffering of HIV-positive children. We need to develop a better understanding of the backgrou...

journal_title：Journal of the International AIDS Society

authors： Kikuchi K,Poudel KC,Muganda J,Sato T,Mutabazi V,Muhayimpundu R,Majyambere A,Nyonsenga SP,Sase E,Jimba M

更新日期：2014-12-03 00:00:00

abstract：INTRODUCTION:Outbreaks of hepatitis C virus (HCV) infections among HIV-positive men who have sex with men (MSM) have been observed globally. Using a multi-modelling approach we estimate the time and number of direct-acting antiviral treatment courses required to achieve an 80% reduction in HCV prevalence among HIV-posi...

journal_title：Journal of the International AIDS Society

authors： Scott N,Stoové M,Wilson DP,Keiser O,El-Hayek C,Doyle J,Hellard M

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Long-term regular clinic follow up is an important component of HIV care. We determined the frequency and characteristics of HIV-infected patients lost to follow up from a London HIV clinic, and factors associated with loss to all HIV follow up in the UK. METHODS:We identified 1859 HIV-infected adults who h...

journal_title：Journal of the International AIDS Society

authors： Gerver SM,Chadborn TR,Ibrahim F,Vatsa B,Delpech VC,Easterbrook PJ

更新日期：2010-08-04 00:00:00

abstract：INTRODUCTION:Preventive therapy is essential for reducing tuberculosis (TB) burden among people living with HIV (PLWH) in high-burden settings. Short-course preventive therapy regimens, such as three-month weekly rifapentine and isoniazid (3HP) and one-month daily rifapentine and isoniazid (1HP), may help facilitate up...

journal_title：Journal of the International AIDS Society

authors： Ferguson O,Jo Y,Pennington J,Johnson K,Chaisson RE,Churchyard G,Dowdy D

更新日期：2020-10-01 00:00:00

abstract：INTRODUCTION:Critical technological advances have yielded a toolkit of HIV prevention strategies. This literature review sought to provide contextual and historical reflection needed to bridge the conceptual gap between clinical efficacy and community effectiveness (i.e. knowledge and usage) of existing HIV prevention ...

journal_title：Journal of the International AIDS Society

authors： Parker RG,Perez-Brumer A,Garcia J,Gavigan K,Ramirez A,Milnor J,Terto V Jr

更新日期：2016-09-30 00:00:00

abstract：INTRODUCTION:Ethiopia has recently adopted lifelong antiretroviral therapy (ART) for all HIV-positive pregnant and breastfeeding women (Option B+ strategy), regardless of CD4 count or clinical stage. However, the exact timing and predictors of loss to follow-up (LFU) are unknown. Thus, we examined the levels and determ...

journal_title：Journal of the International AIDS Society

authors： Mitiku I,Arefayne M,Mesfin Y,Gizaw M

更新日期：2016-03-21 00:00:00

abstract：:While there has been remarkable progress in understanding the biology of HIV-1 and its recognition by the human immune system, we have not yet developed an efficacious HIV-1 vaccine. Vaccine challenges include the genetic diversity and mutability of HIV-1 which create a plethora of constantly changing antigens, the st...

journal_title：Journal of the International AIDS Society

authors： Kwong PD,Mascola JR,Nabel GJ

更新日期：2012-07-05 00:00:00

abstract：BACKGROUND:The majority of new HIV infections are acquired through heterosexual transmission. There is urgent need for prevention methods to compliment behavior change and condom use. Topical microbicide represent a potential strategy for reduction of HIV transmission in women. METHODS:Monthly Colposcopy evaluations w...

journal_title：Journal of the International AIDS Society

authors： Chirenje ZM,Mâsse BR,Maslankowski LA,Ramjee G,Coletti AS,Tembo TN,Magure TM,Soto-Torres L,Kelly C,Hillier S,Karim A

更新日期：2012-08-27 00:00:00

abstract：INTRODUCTION:Mortality among HIV-positive adults awaiting antiretroviral therapy (ART) has previously been found to be high. Here, we compare adolescent pre-ART mortality to that of adults in a public sector HIV care programme in Bulawayo, Zimbabwe. METHODS:In this retrospective cohort study, we compared adolescent pr...

journal_title：Journal of the International AIDS Society

authors： Shroufi A,Ndebele W,Nyathi M,Gunguwo H,Dixon M,Saint-Sauveur JF,Taziwa F,Viñoles MC,Ferrand RA

更新日期：2015-02-23 00:00:00

abstract：INTRODUCTION:Modern combined antiretroviral therapies (cART) allow to effectively suppress HIV-1 viral load, with the 90% virologic success rate, meeting the WHO target in most clinical settings. The aim of this study was to analyse antiretroviral treatment efficacy in Poland and to identify variables associated with v...

journal_title：Journal of the International AIDS Society

authors： Parczewski M,Siwak E,Leszczyszyn-Pynka M,Cielniak I,Burkacka E,Pulik P,Witor A,Muller K,Zasik E,Grzeszczuk A,Jankowska M,Lemańska M,Olczak A,Grąbczewska E,Szymczak A,Gąsiorowski J,Szetela B,Bociąga-Jasik M,Skwara P,

更新日期：2017-07-17 00:00:00

abstract：INTRODUCTION:Identifying appropriate pre-exposure prophylaxis (PrEP) candidates is a challenge in planning for the safe and effective roll-out of this strategy. We explored the use of a validated HIV risk screening tool, HIV Incidence Risk Index for Men who have Sex with Men (HIRI-MSM), to identify "optimal" candidates...

journal_title：Journal of the International AIDS Society

authors： Wilton J,Kain T,Fowler S,Hart TA,Grennan T,Maxwell J,Tan DH

更新日期：2016-06-03 00:00:00

abstract：INTRODUCTION:A key objective of combined antiretroviral therapy (cART) is to reach and maintain high CD4 cell counts to provide long-term protection against AIDS-defining opportunistic infections and malignancies, as well as other comorbidities. However, a high proportion of patients present late for care. Our objectiv...

journal_title：Journal of the International AIDS Society

authors： Costagliola D,Lacombe JM,Ghosn J,Delaugerre C,Pialoux G,Cuzin L,Launay O,Ménard A,de Truchis P,Mary-Krause M,Weiss L,Delfraissy JF

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Older adults living with HIV (OALHIV; ≥50 years) who use drugs face unique needs and challenges that compromise their health and wellbeing due to the structural and environmental barriers they experience, in addition to being disproportionately affected by comorbidities. Nevertheless, research on this popu...

journal_title：Journal of the International AIDS Society

authors： Chayama KL,Ng C,McNeil R

更新日期：2020-08-01 00:00:00

abstract：INTRODUCTION:The Amsterdam PrEP project is a prospective, open-label demonstration study at a large sexually transmitted infection (STI) clinic. We examined the uptake of PrEP; the baseline characteristics of men who have sex with men (MSM) and transgender persons initiating PrEP; their choices of daily versus event-dr...

journal_title：Journal of the International AIDS Society

authors： Hoornenborg E,Achterbergh RC,van der Loeff MFS,Davidovich U,van der Helm JJ,Hogewoning A,van Duijnhoven YT,Sonder GJ,de Vries HJ,Prins M,Amsterdam PrEP Project team in the HIV Transmission Elimination AMsterdam Initiative.

更新日期：2018-03-01 00:00:00

abstract：INTRODUCTION:Qualitative research on antiretroviral therapy (ART) adherence interventions can provide a deeper understanding of intervention facilitators and barriers. This systematic review aims to synthesize qualitative evidence of interventions for improving ART adherence and to inform patient-centred policymaking. ...

journal_title：Journal of the International AIDS Society

authors： Ma Q,Tso LS,Rich ZC,Hall BJ,Beanland R,Li H,Lackey M,Hu F,Cai W,Doherty M,Tucker JD

更新日期：2016-10-17 00:00:00

abstract：INTRODUCTION:Lopinavir/ritonavir-based antiretroviral therapy (ART) is recommended for all HIV-infected children less than three years. However, little is known about its field implementation and effectiveness in West Africa. We assessed the 12-month response to lopinavir/ritonavir-based antiretroviral therapy in a coh...

journal_title：Journal of the International AIDS Society

authors： Amani-Bosse C,Dahourou DL,Malateste K,Amorissani-Folquet M,Coulibaly M,Dattez S,Emieme A,Barry M,Rouzioux C,N'gbeche S,Yonaba C,Timité-Konan M,Mea V,Ouédraogo S,Blanche S,Meda N,Seguin-Devaux C,Leroy V

更新日期：2017-04-25 00:00:00

abstract：:Family-based interventions with children who are affected by HIV and AIDS are not well established. The Collaborative HIV Prevention and Adolescent Mental Health Program (CHAMP) represents one of the few evidence-based interventions tested in low-income contexts in the US, Caribbean and South Africa. This paper provid...

journal_title：Journal of the International AIDS Society

authors： Bhana A,McKay MM,Mellins C,Petersen I,Bell C

更新日期：2010-06-23 00:00:00

abstract：:Potent antiretroviral therapy (ART) reduces mortality and morbidity in people living with HIV by reducing viral load and allowing their immune systems to recover. The reduction in viral load soon after starting ART has led to the hypothesis that early and widespread ART could prevent onward transmission and therefore ...

journal_title：Journal of the International AIDS Society

authors： Williams B,Wood R,Dukay V,Delva W,Ginsburg D,Hargrove J,Stander M,Sheneberger R,Montaner J,Welte A

更新日期：2011-07-06 00:00:00

abstract：INTRODUCTION:Cenicriviroc (CVC), a once-daily, dual CCR5/CCR2 co-receptor antagonist, has completed Phase 2b development. CVC demonstrated favourable safety and similar efficacy compared with efavirenz (EFV) in Study 202 (NCT01338883); an ex vivo sub-analysis evaluated treatment effects on HIV entry, measured by intrac...

journal_title：Journal of the International AIDS Society

authors： Kramer V,Hassounah S,Colby-Germinario S,Mesplède T,Lefebvre E,Wainberg M

更新日期：2014-11-02 00:00:00

abstract：BACKGROUND:Volunteer caregivers are a critical source of support for the majority of people living with HIV and AIDS in southern Africa, which has extremely high HIV/AIDS prevalence rates. While studies have shown that volunteer caregiving is associated with negative health and socio-economic outcomes, little is known ...

journal_title：Journal of the International AIDS Society

authors： Akintola O

更新日期：2010-06-14 00:00:00

abstract：:[This corrects the article DOI: 10.7448/IAS.20.01/21317.]. ...

journal_title：Journal of the International AIDS Society

authors：

更新日期：2017-06-02 00:00:00

abstract：INTRODUCTION:The relative efficacy of different antiretroviral (ART) regimens has been extensively evaluated in the context of clinical trials, using HIV viral load (VL) measurements at pre-specified timepoints after ART onset. However, data from real-life studies using combined longitudinal measurements of cumulative ...

journal_title：Journal of the International AIDS Society

authors： Pascom AR,Pinho RE,Rick F,Veras NM,Perini FB,Meireles MV,Pereira GF,Benzaken AS,Avelino-Silva VI

更新日期：2019-11-01 00:00:00

abstract：INTRODUCTION:Optimal adherence to antiretroviral therapy is closely related with suppression of the HIV viral load in plasma, slowing disease progression and decreasing HIV transmission rates. Despite its importance, the estimated proportion of people living with HIV in Latin America and the Caribbean with optimal adhe...

journal_title：Journal of the International AIDS Society

authors： Costa JM,Torres TS,Coelho LE,Luz PM

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:Switching to a rilpivirine, tenofovir and emtricitabine (RTE) single-tablet regimen (STR) has been evaluated in a limited number of virologically suppressed patients. The aim of this study was to describe clinical outcomes in HIV-positive patients switched from a suppressive antiretroviral regimen to RTE S...

journal_title：Journal of the International AIDS Society

authors： Gianotti N,Poli A,Nozza S,Spagnuolo V,Tambussi G,Bossolasco S,Cinque P,Maillard M,Cernuschi M,Galli L,Lazzarin A,Castagna A

更新日期：2015-07-30 00:00:00

abstract：INTRODUCTION:Antiretroviral (ARV)-based pre-exposure prophylaxis (PrEP) is a promising new HIV prevention strategy. However, variable levels of adherence have yielded mixed results across several PrEP trials and populations. It is not clear how taking ARV - traditionally used for HIV treatment - is perceived and how th...

journal_title：Journal of the International AIDS Society

authors： van der Straten A,Stadler J,Luecke E,Laborde N,Hartmann M,Montgomery ET,VOICE-C Study Team.

更新日期：2014-09-08 00:00:00

abstract：INTRODUCTION:The 48-week interim analysis of the MODAT study showed that confirmed virologic failure (CVF) was more frequent in patients simplifying to ATV/r monotherapy compared to maintaining ATV/r-based triple therapy. The DSMB recommended stopping study enrollment but continuing follow-up of enrolled patients. We p...

journal_title：Journal of the International AIDS Society

authors： Spagnuolo V,Galli L,Bigoloni A,Nozza S,Monforte Ad,Antinori A,Di Biagio A,Rusconi S,Guaraldi G,Di Giambenedetto S,Lazzarin A,Castagna A

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:People living with HIV (PLHIV) have the right to exercise voluntary choices about their health, including their reproductive health. This commentary discusses the integral role that family planning (FP) plays in helping PLHIV, including those in serodiscordant relationships, achieve conception safely. The ...

journal_title：Journal of the International AIDS Society

authors： Mason J,Medley A,Yeiser S,Nightingale VR,Mani N,Sripipatana T,Abutu A,Johnston B,Watts DH

更新日期：2017-03-08 00:00:00