Pharmacokinetics-based adherence measures for antiretroviral therapy in HIV-infected Kenyan children.

abstract：INTRODUCTION:Clinicians often do not have the time and possibilities to read all scientific evidence necessary to maintain high quality patient care. They rely on guidelines made by experts to help them in their daily work. METHODS:We compared the 2012 recommendations and the arguments of the IAS-USA Panel with the da...

journal_title：Journal of the International AIDS Society

authors： Piso RJ

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Consistent use of PrEP reduces HIV transmission from sexual practices amongst men who have sex with men (MSM) up to 92% [1]. Lisbon MSM cohort study estimates point that 59.3% of their participants at entrance (1593 HIV negative MSM enrolled between April 2011 and May 2013) were eligible for PrEP [2], acco...

journal_title：Journal of the International AIDS Society

authors： Rocha LM,Campos MJ,Brito J,Fuertes R,Rojas J,Pinto N,Mendão L,Esteves J

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Globally, young gay, bisexual and other men who have sex with men (gbMSM) continue to experience disproportionately high rates of HIV and other sexually transmitted and blood-borne infections (STBBIs). As such, there are strong public health imperatives to evaluate innovative prevention, treatment and care...

journal_title：Journal of the International AIDS Society

authors： Knight R,Karamouzian M,Salway T,Gilbert M,Shoveller J

更新日期：2017-11-01 00:00:00

abstract：INTRODUCTION:Antiretroviral therapy (ART) substantially improves the health of people living with HIV and contributes to preventing new infections. While HIV incidence is decreasing in most regions, the epidemic in eastern Europe continues to rise, as new infections currently outnumber the rate of ART initiation. In th...

journal_title：Journal of the International AIDS Society

authors： Mallitt KA,Grigoryan SR,Papoyan AS,Wand HC,Wilson DP

更新日期：2014-08-04 00:00:00

abstract：INTRODUCTION:To be used most effectively, pre-exposure prophylaxis (PrEP) should be prioritized to those at high risk of acquisition and would ideally be aligned with time periods of increased exposure. Identifying such time periods is not always straightforward, however. Gaza Province in southern Mozambique is charact...

journal_title：Journal of the International AIDS Society

authors： Cremin I,Morales F,Jewell BL,O'Reilly KR,Hallett TB

更新日期：2015-07-20 00:00:00

abstract：INTRODUCTION:The HIV Strategy in New South Wales (NSW) Australia aims to virtually eliminate HIV transmission by 2020. We estimated the 2016 HIV diagnosis and care cascade for the state of NSW, with a focus on introducing population-based data to improve data quality and assess progress towards the UNAIDS 90-90-90 targ...

journal_title：Journal of the International AIDS Society

authors： Keen P,Gray RT,Telfer B,Guy R,Schmidt HM,Whittaker B,Holden J,Holt M,Kelleher A,Wilson D,Callander D,Cooper DA,Prestage G,Selvey C,Grulich AE,NSW HIV Prevention Partnership Project.

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:In 2016, the Global Health Sector Strategy (GHSS) on viral hepatitis called for elimination of viral hepatitis as a major public health threat by 2030 (i.e. 90% reduction in incidence and 65% in mortality). In 2017, WHO's first-ever Global Hepatitis Report presented the baseline values for each of the core...

journal_title：Journal of the International AIDS Society

authors： Hutin YJ,Bulterys M,Hirnschall GO

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:Injecting drug use (IDU) is associated with tuberculosis but few data are available from low-income settings. We examined IDU in relation to active and latent tuberculosis (LTBI) among HIV-positive individuals in Indonesia, which has a high burden of tuberculosis and a rapidly growing HIV epidemic strongly...

journal_title：Journal of the International AIDS Society

authors： Meijerink H,Wisaksana R,Lestari M,Meilana I,Chaidir L,van der Ven AJ,Alisjahbana B,van Crevel R

更新日期：2015-02-16 00:00:00

abstract：INTRODUCTION:This was a descriptive non-interventional study in HIV-1-infected patients treated with DRV/r conducted in the clinical setting, with a single-arm prospective design. The primary objective was to collect data on utilization of darunavir/ritonavir (DRV/r) under the conditions described in the marketing auth...

journal_title：Journal of the International AIDS Society

authors： Antinori A,Galli M,Gianotti N,Mussini C,Quirino T,Sterrantino K,Mancusi D,Termini R

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:The success of HIV treatment programmes globally has resulted in children with perinatally acquired HIV reaching adolescence in large numbers. The number of adolescents living with HIV is growing further due to persisting high HIV incidence rates among adolescents in low- and middle-income settings, partic...

journal_title：Journal of the International AIDS Society

authors： Marcus R,Ferrand RA,Kranzer K,Bekker LG

更新日期：2017-11-01 00:00:00

abstract：INTRODUCTION:Poor access of lesbian, gay, bisexual and transgender (LGBT) people to healthcare providers with clinical and cultural competency contributes to health inequalities between heterosexual/cisgender and LGBT people. This systematic review assesses the effect of educational curricula and training for healthcar...

journal_title：Journal of the International AIDS Society

authors： Sekoni AO,Gale NK,Manga-Atangana B,Bhadhuri A,Jolly K

更新日期：2017-07-19 00:00:00

abstract：INTRODUCTION:The evolving HIV epidemic, coupled with advances in HIV treatment, has resulted in an ageing HIV-diagnosed population. It has been suggested that adverse physical and psychological effects of HIV may be higher among older people. However, few studies have examined the effect of older age on well-being for ...

journal_title：Journal of the International AIDS Society

authors： McGowan J,Sherr L,Rodger A,Fisher M,Miners A,Johnson M,Elford J,Collins S,Hart G,Phillips A,Speakman A,Lampe F

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Every year, approximately 260,000 children are infected with HIV in low- and middle-income countries. The timely initiation and high level of maintenance of antiretroviral therapy (ART) are crucial to reducing the suffering of HIV-positive children. We need to develop a better understanding of the backgrou...

journal_title：Journal of the International AIDS Society

authors： Kikuchi K,Poudel KC,Muganda J,Sato T,Mutabazi V,Muhayimpundu R,Majyambere A,Nyonsenga SP,Sase E,Jimba M

更新日期：2014-12-03 00:00:00

abstract：INTRODUCTION:HIV testing is an essential prerequisite for accessing treatment with antiretroviral therapy or prevention using pre-exposure prophylaxis. Internet distribution of HIV self-tests is a novel approach, and data on the programmatic cost of this approach are limited. We analyse the costs and cost-effectiveness...

journal_title：Journal of the International AIDS Society

authors： Shrestha RK,Chavez PR,Noble M,Sansom SL,Sullivan PS,Mermin JH,MacGowan RJ

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Inadequate knowledge, negative attitudes and risky practices are major hindrances to preventing the spread of HIV. This study aimed to assess HIV-related knowledge, attitudes and practices (KAPs) of high school students in Lao People's Democratic Republic (PDR). METHODS:A cross-sectional study on unmarrie...

journal_title：Journal of the International AIDS Society

authors： Thanavanh B,Harun-Or-Rashid M,Kasuya H,Sakamoto J

更新日期：2013-03-11 00:00:00

abstract：BACKGROUND:The majority of new HIV infections are acquired through heterosexual transmission. There is urgent need for prevention methods to compliment behavior change and condom use. Topical microbicide represent a potential strategy for reduction of HIV transmission in women. METHODS:Monthly Colposcopy evaluations w...

journal_title：Journal of the International AIDS Society

authors： Chirenje ZM,Mâsse BR,Maslankowski LA,Ramjee G,Coletti AS,Tembo TN,Magure TM,Soto-Torres L,Kelly C,Hillier S,Karim A

更新日期：2012-08-27 00:00:00

abstract：INTRODUCTION:There is great interest for integrating care for non-communicable diseases (NCDs) into routine HIV services in sub-Saharan Africa (SSA) due to the steady rise of the number of people who are ageing with HIV. Suggested health system approaches for intervening on these comorbidities have mostly been normativ...

journal_title：Journal of the International AIDS Society

authors： Kintu A,Sando D,Okello S,Mutungi G,Guwatudde D,Menzies NA,Danaei G,Verguet S

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:HIV-controllers have the ability to spontaneously maintain viraemia at low or undetectable levels in the absence of antiretroviral treatment. Furthermore, HIV-controllers seem to have a superior capacity to spontaneously clear hepatitis C virus (HCV) compared to non HIV-controllers. Some of these subjects ...

journal_title：Journal of the International AIDS Society

authors： Dominguez-Molina B,Tarancon-Diez L,Milanés-Guisado Y,Genebat M,Resino S,Rodriguez C,Gonzalez-García J,Rallón N,Pernas M,Casado C,Lopez-Galíndez C,León A,Benito JM,García F,Del Romero J,Viciana P,Lopez-Cortes LF,Leal M,

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:Anaemia is prevalent among children born to HIV-positive women, and it is associated with adverse effects on cognitive and motor development, growth, and increased risks of morbidity and mortality. OBJECTIVE:To examine the effect of daily multivitamin supplementation on haematologic status and mother-to-c...

journal_title：Journal of the International AIDS Society

authors： Liu E,Duggan C,Manji KP,Kupka R,Aboud S,Bosch RJ,Kisenge RR,Okuma J,Fawzi WW

更新日期：2013-08-13 00:00:00

abstract：:Family-based interventions with children who are affected by HIV and AIDS are not well established. The Collaborative HIV Prevention and Adolescent Mental Health Program (CHAMP) represents one of the few evidence-based interventions tested in low-income contexts in the US, Caribbean and South Africa. This paper provid...

journal_title：Journal of the International AIDS Society

authors： Bhana A,McKay MM,Mellins C,Petersen I,Bell C

更新日期：2010-06-23 00:00:00

abstract：INTRODUCTION:We report the SVR12 final analysis of a phase 3 study of telaprevir in combination with peginterferon (P)/ribavirin (R) in HCV-genotype 1, treatment-naïve and -experienced patients with HCV/HIV co-infection (INSIGHT). MATERIALS AND METHODS:Patients receiving stable, suppressive HIV antiretroviral (ARV) th...

journal_title：Journal of the International AIDS Society

authors： Montes M,Nelson M,Girard PM,Sasadeusz J,Horban A,Grinsztejn B,Zakharova N,Rivero A,Lathouwers E,Janssen K,Ouwerkerk-Mahadevan S,Witek J

更新日期：2014-11-02 00:00:00

abstract：:Eastern Europe and Central Asia have the largest drug epidemic globally and the fastest and still expanding HIV epidemic. The Russian Federation and Ukraine together account for over 90% of the reported AIDS cases in the region. If small in absolute numbers, the epidemics are however significant in prevalence rate in ...

journal_title：Journal of the International AIDS Society

authors： Kazatchkine M

更新日期：2014-11-02 00:00:00

abstract：BACKGROUND:Long-term regular clinic follow up is an important component of HIV care. We determined the frequency and characteristics of HIV-infected patients lost to follow up from a London HIV clinic, and factors associated with loss to all HIV follow up in the UK. METHODS:We identified 1859 HIV-infected adults who h...

journal_title：Journal of the International AIDS Society

authors： Gerver SM,Chadborn TR,Ibrahim F,Vatsa B,Delpech VC,Easterbrook PJ

更新日期：2010-08-04 00:00:00

abstract：INTRODUCTION:In 2014 the Joint United Nations Programme on HIV/AIDS defined the ambitious 90-90-90 targets for 2020, in which 90% of people living with HIV must be diagnosed, 90% of those diagnosed should be on sustained therapy and 90% of those on therapy should have an undetectable viral load. Children are considered...

journal_title：Journal of the International AIDS Society

authors： Rabie H,Frigati L,Hesseling AC,Garcia-Prats AJ

更新日期：2015-12-02 00:00:00

abstract：INTRODUCTION:People living with HIV (PLHIV) on antiretroviral therapy (ART) experience high rates of non-communicable diseases (NCDs). These co-morbidities often accumulate and older adults may suffer from multimorbidity. Multimorbidity has been associated with loss of quality of life, polypharmacy, and increased risk ...

journal_title：Journal of the International AIDS Society

authors： Castilho JL,Escuder MM,Veloso V,Gomes JO,Jayathilake K,Ribeiro S,Souza RA,Ikeda ML,de Alencastro PR,Tupinanbas U,Brites C,McGowan CC,Grangeiro A,Grinsztejn B

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Treatment as prevention has mobilized new opportunities in preventing HIV transmission and has led to bold new UNAIDS targets in testing, treatment coverage and transmission reduction. These will require not only an increase in investment but also a deeper understanding of the dynamics of combining behavio...

journal_title：Journal of the International AIDS Society

authors： Brown G,Reeders D,Dowsett GW,Ellard J,Carman M,Hendry N,Wallace J

更新日期：2015-12-14 00:00:00

abstract：BACKGROUND:Injection drug use remains a major risk factor for HIV transmission in Georgia. The study aims to characterize the prevalence of HIV among injection drug users in Georgia. METHODS:A cross-sectional, anonymous bio-behavioural survey to assess knowledge and behaviour in injection drug users in combination wit...

journal_title：Journal of the International AIDS Society

authors： Chikovani I,Goguadze K,Ranade S,Wertlieb M,Rukhadze N,Gotsadze G

更新日期：2011-02-15 00:00:00

abstract：INTRODUCTION:Critical technological advances have yielded a toolkit of HIV prevention strategies. This literature review sought to provide contextual and historical reflection needed to bridge the conceptual gap between clinical efficacy and community effectiveness (i.e. knowledge and usage) of existing HIV prevention ...

journal_title：Journal of the International AIDS Society

authors： Parker RG,Perez-Brumer A,Garcia J,Gavigan K,Ramirez A,Milnor J,Terto V Jr

更新日期：2016-09-30 00:00:00

abstract：INTRODUCTION:Lamivudine (3TC) and emtricitabine (FTC) are considered interchangeable by HIV-1 guidelines in first-line tenofovir/efavirenz (TDF/EFV) and TDF/nevirapine (NVP) combination antiretroviral therapy (cART). Data from trials on equivalence of 3TC and FTC are inconsistent. We examined the effectiveness of 3TC a...

journal_title：Journal of the International AIDS Society

authors： Rokx C,Fibriani A,van de Vijver D,Verbon A,Schutten M,Gras L,Rijnders BJ

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Dolutegravir is a second generation integrase inhibitor with a proposed high genetic barrier to resistance. However, in clinical trials, decreased virological response was seen in a subset of patients with prior exposure to raltegravir and multiple integrase resistance mutations. METHODS:We describe two c...

journal_title：Journal of the International AIDS Society

authors： Hofstra LM,Nijhuis M,Mudrikova T,Fun A,Schipper P,Schneider M,Wensing A

更新日期：2014-11-02 00:00:00