Seasonal PrEP for partners of migrant miners in southern Mozambique: a highly focused PrEP intervention.

abstract：INTRODUCTION:Pre-treatment HIV drug resistance (PDR) is an increasing problem in sub-Saharan Africa. Children are an especially vulnerable population to develop PDR given that paediatric second-line treatment options are limited. Although monitoring of PDR is important, data on the paediatric prevalence in sub-Saharan ...

journal_title：Journal of the International AIDS Society

authors： Boerma RS,Boender TS,Sigaloff KC,Rinke de Wit TF,van Hensbroek MB,Ndembi N,Adeyemo T,Temiye EO,Osibogun A,Ondoa P,Calis JC,Akanmu AS

更新日期：2016-11-10 00:00:00

abstract：INTRODUCTION:Since June 2016, the national HIV programme in Malawi has adopted Universal Test and Treat (UTT) guidelines requiring that all persons who test HIV positive will be referred to start antiretroviral therapy (ART). Although there is strong evidence from clinical trials that early initiation of ART leads to r...

journal_title：Journal of the International AIDS Society

authors： Alhaj M,Amberbir A,Singogo E,Banda V,van Lettow M,Matengeni A,Kawalazira G,Theu J,Jagriti MR,Chan AK,van Oosterhout JJ

更新日期：2019-02-01 00:00:00

abstract：INTRODUCTION:Despite recent advances in the management of HIV infection and increased access to treatment, prevention, care and support, the HIV/AIDS epidemic continues to be a major global health problem, with sub-Saharan Africa suffering by far the greatest humanitarian, demographic and socio-economic burden of the e...

journal_title：Journal of the International AIDS Society

authors： Divaris K,Newman J,Hemingway-Foday J,Akam W,Balimba A,Dusengamungu C,Kalenga L,Mbaya M,Molu BM,Mugisha V,Mukumbi H,Mushingantahe J,Nash D,Niyongabo T,Atibu J,Azinyue I,Kiumbu M,Woelk G

更新日期：2012-11-21 00:00:00

abstract：INTRODUCTION:The HIV epidemics in the Caribbean, Central America and South America (CCASA), Eastern Europe (EE) and Asia and Pacific (AP) regions are diverse epidemics affecting different key populations in predominantly middle-income countries. This narrative review describes the populations of HIV-positive youth appr...

journal_title：Journal of the International AIDS Society

authors： Bailey H,Cruz MLS,Songtaweesin WN,Puthanakit T

更新日期：2017-05-16 00:00:00

abstract：INTRODUCTION:Vaginal tenofovir (TFV) 1% gel may reduce incident HIV-1 and herpes simplex virus 2 infection. Pregnancy may increase risk of HIV acquisition, and incident HIV in pregnancy potentiates perinatal HIV transmission. Our objective was to investigate the safety and pharmacokinetics of seven days of TFV 1% vagin...

journal_title：Journal of the International AIDS Society

authors： Beigi RH,Noguchi LM,Montgomery E,Biggio J,Hendrix CW,Marzinke MA,Dai JY,Pan J,Kunjara Na Ayudhya R,Schwartz JL,Isaacs K,Piper JM,Watts DH

更新日期：2016-09-21 00:00:00

abstract：INTRODUCTION:Although RTS as HIV Diagnosis was considered cost effectiveness [1], overall budget may be unaffordable for some countries. We explore Incremental cost per NDHI associated with different TS. MATERIALS AND METHODS:From a health care perspective, using direct costs and Euros currency, we calculated budget a...

journal_title：Journal of the International AIDS Society

authors： Gomez-Ayerbe C,Elías MJ,Muriel A,Elías PP,Cano A,Diaz A,Moreno A,Casado JL,Santos C,Martinez-Colubi M,Uranga A,Dronda F,Moreno S

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Global guidelines emphasize the ethical obligation of investigators to help participants in HIV-endpoint trials reduce HIV risk by offering an optimal HIV prevention package. Oral pre-exposure prophylaxis (PrEP) has increasingly become part of state-of-the-art HIV prevention. Here we describe the process o...

journal_title：Journal of the International AIDS Society

authors： Beesham I,Welch JD,Heffron R,Pleaner M,Kidoguchi L,Palanee-Phillips T,Ahmed K,Baron D,Bukusi EA,Louw C,Mastro TD,Smit J,Batting JR,Malahleha M,Bailey VC,Beksinska M,Donnell D,Baeten JM,ECHO Trial Consortium.

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Psychological factors are often neglected in HIV research, although psychological distress is common in low- to middle-income countries, such as South Africa. There is a need to deepen our understanding of the role of mental health factors in the HIV epidemic. We set out to investigate whether baseline depre...

journal_title：Journal of the International AIDS Society

authors： Nduna M,Jewkes RK,Dunkle KL,Shai NP,Colman I

更新日期：2010-11-15 00:00:00

abstract：INTRODUCTION:Due to their low CNS penetrance, there are concerns about the capacity of non-conventional PI-based ART (monotherapy and dual therapies) to preserve neurocognitive performance (NP). METHODS:We evaluated the NP change of aviremic participants of the SALT clinical trial (1) switching therapy to dual therapy...

journal_title：Journal of the International AIDS Society

authors： Valero IP,Pasquau J,Rubio R,Ribero A,Santos J,Sanz J,Mariño A,Crespo M,Hernandez J,Iribarren JA,Gutierrez F,Terron A,Esteban H,Pérez-Molina JA

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Preventive therapy is essential for reducing tuberculosis (TB) burden among people living with HIV (PLWH) in high-burden settings. Short-course preventive therapy regimens, such as three-month weekly rifapentine and isoniazid (3HP) and one-month daily rifapentine and isoniazid (1HP), may help facilitate up...

journal_title：Journal of the International AIDS Society

authors： Ferguson O,Jo Y,Pennington J,Johnson K,Chaisson RE,Churchyard G,Dowdy D

更新日期：2020-10-01 00:00:00

abstract：INTRODUCTION:Anaemia is prevalent among children born to HIV-positive women, and it is associated with adverse effects on cognitive and motor development, growth, and increased risks of morbidity and mortality. OBJECTIVE:To examine the effect of daily multivitamin supplementation on haematologic status and mother-to-c...

journal_title：Journal of the International AIDS Society

authors： Liu E,Duggan C,Manji KP,Kupka R,Aboud S,Bosch RJ,Kisenge RR,Okuma J,Fawzi WW

更新日期：2013-08-13 00:00:00

abstract：BACKGROUND:Micronutrient deficiencies compromise the survival of HIV-infected children in low-income countries. We assessed the effect of multiple micronutrient supplementation on the mortality of HIV-infected children in Uganda. METHODS:In a randomized, controlled trial, 847 children aged one to five years and attend...

journal_title：Journal of the International AIDS Society

authors： Ndeezi G,Tylleskär T,Ndugwa CM,Tumwine JK

更新日期：2010-06-03 00:00:00

abstract：INTRODUCTION:We report the SVR12 final analysis of a phase 3 study of telaprevir in combination with peginterferon (P)/ribavirin (R) in HCV-genotype 1, treatment-naïve and -experienced patients with HCV/HIV co-infection (INSIGHT). MATERIALS AND METHODS:Patients receiving stable, suppressive HIV antiretroviral (ARV) th...

journal_title：Journal of the International AIDS Society

authors： Montes M,Nelson M,Girard PM,Sasadeusz J,Horban A,Grinsztejn B,Zakharova N,Rivero A,Lathouwers E,Janssen K,Ouwerkerk-Mahadevan S,Witek J

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Current healthcare systems fail to provide adequate HIV services to men. In Zambia, 25% of adult men living with HIV were unaware of their HIV status in 2018, and 12% of those who were unaware of their HIV statu were not receiving antiretroviral therapy (ART) due to pervasive barriers to HIV testing servic...

journal_title：Journal of the International AIDS Society

authors： Mwango LK,Stafford KA,Blanco NC,Lavoie MC,Mujansi M,Nyirongo N,Tembo K,Sakala H,Chipukuma J,Phiri B,Nzangwa C,Mwandila S,Nkwemu KC,Saadani A,Mwila A,Herce ME,Claassen CW

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:Gonorrhoea and chlamydia cases have been rising among gay, bisexual and other men who have sex with men (MSM) over the last decade. The majority of cases are extragenital and occur at the oropharynx and anorectum. The aim of this narrative review was to review the risk factors and mode of transmission for ...

journal_title：Journal of the International AIDS Society

authors： Chow EP,Fairley CK

更新日期：2019-08-01 00:00:00

abstract：INTRODUCTION:There are limited data characterizing the burden of HIV among men who have sex with men (MSM) in Malawi. Epidemiologic research and access to HIV prevention, treatment and care services have been traditionally limited in Malawi by criminalization and stigmatization of same-sex practices. To inform the deve...

journal_title：Journal of the International AIDS Society

authors： Wirtz AL,Jumbe V,Trapence G,Kamba D,Umar E,Ketende S,Berry M,Strömdahl S,Beyrer C,Baral SD

更新日期：2013-12-02 00:00:00

abstract：INTRODUCTION:Cardiovascular diseases are increasing in aging HIV-positive patients (HIV+). Impact of traditional cardiovascular risk factors, HIV-specific parameters and antiretroviral therapy (ART) on the incidence of cardiovascular events (CVE) and on the mortality rate are investigated in different HIV+ cohorts. ME...

journal_title：Journal of the International AIDS Society

authors： Esser S,Eisele L,Schwarz B,Schulze C,Holzendorf V,Brockmeyer NH,Hower M,Kwirant F,Rudolph R,Neumann T,Reinsch N

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Worldwide, 71 million people are infected with hepatitis C virus (HCV), which, without treatment, can lead to liver failure or hepatocellular carcinoma. HCV co-infection increases liver- and AIDS-related morbidity and mortality among HIV-positive people, despite ART. A 12-week course of HCV direct-acting a...

journal_title：Journal of the International AIDS Society

authors： Grillon C,Krishtel PR,Mellouk O,Basenko A,Freeman J,Mendão L,Andrieux-Meyer I,Morin S

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:In response to the increasing burden of HIV, the Ugandan government has employed different service delivery models since 2004 that aim to reduce costs and remove barriers to accessing HIV care. These models include community-based approaches to delivering antiretroviral therapy (ART) and delegating tasks t...

journal_title：Journal of the International AIDS Society

authors： Vu L,Waliggo S,Zieman B,Jani N,Buzaalirwa L,Okoboi S,Okal J,Borse NN,Kalibala S

更新日期：2016-07-20 00:00:00

abstract：INTRODUCTION:In 2016, the Global Health Sector Strategy (GHSS) on viral hepatitis called for elimination of viral hepatitis as a major public health threat by 2030 (i.e. 90% reduction in incidence and 65% in mortality). In 2017, WHO's first-ever Global Hepatitis Report presented the baseline values for each of the core...

journal_title：Journal of the International AIDS Society

authors： Hutin YJ,Bulterys M,Hirnschall GO

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:Safer conception strategies minimize HIV risk during condomless sex to become pregnant. Gaps remain in understanding the acceptability, feasibility and choices HIV-serodiscordant couples make when multiple safer conception options are available. METHODS:We conducted a pilot study of a comprehensive safer ...

journal_title：Journal of the International AIDS Society

authors： Heffron R,Ngure K,Velloza J,Kiptinness C,Quame-Amalgo J,Oluch L,Thuo N,Njoroge J,Momanyi R,Gakuo S,Mbugua S,Morrison S,Haugen H,Chohan B,Celum C,Baeten JM,Mugo N

更新日期：2019-04-01 00:00:00

abstract：INTRODUCTION:Modern combined antiretroviral therapies (cART) allow to effectively suppress HIV-1 viral load, with the 90% virologic success rate, meeting the WHO target in most clinical settings. The aim of this study was to analyse antiretroviral treatment efficacy in Poland and to identify variables associated with v...

journal_title：Journal of the International AIDS Society

authors： Parczewski M,Siwak E,Leszczyszyn-Pynka M,Cielniak I,Burkacka E,Pulik P,Witor A,Muller K,Zasik E,Grzeszczuk A,Jankowska M,Lemańska M,Olczak A,Grąbczewska E,Szymczak A,Gąsiorowski J,Szetela B,Bociąga-Jasik M,Skwara P,

更新日期：2017-07-17 00:00:00

abstract：INTRODUCTION:The HIV Strategy in New South Wales (NSW) Australia aims to virtually eliminate HIV transmission by 2020. We estimated the 2016 HIV diagnosis and care cascade for the state of NSW, with a focus on introducing population-based data to improve data quality and assess progress towards the UNAIDS 90-90-90 targ...

journal_title：Journal of the International AIDS Society

authors： Keen P,Gray RT,Telfer B,Guy R,Schmidt HM,Whittaker B,Holden J,Holt M,Kelleher A,Wilson D,Callander D,Cooper DA,Prestage G,Selvey C,Grulich AE,NSW HIV Prevention Partnership Project.

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:Cardiovascular disease (CVD) is the leading cause of death in England and Wales. As people living with HIV (PLWH) age, proactive management of CVD risk factors is crucial. The long-awaited draft guidelines for CVD from the National Institute of Clinical Excellence (NICE) propose lipid modification (with st...

journal_title：Journal of the International AIDS Society

authors： Ahmed N,Bradley S,Pearson P,Edwards S,Waters L

更新日期：2014-11-02 00:00:00

abstract：:Paediatric antiretroviral treatment (ART) failure is an under-recognized issue that receives inadequate attention in the field of paediatrics and within HIV treatment programmes. With paediatric ART failure rates ranging from 19.3% to over 32% in resource limited settings, a comprehensive evaluation of the causes of f...

journal_title：Journal of the International AIDS Society

authors： Bernheimer JM,Patten G,Makeleni T,Mantangana N,Dumile N,Goemaere E,Cox V

更新日期：2015-07-23 00:00:00

abstract：INTRODUCTION:Inadequate knowledge, negative attitudes and risky practices are major hindrances to preventing the spread of HIV. This study aimed to assess HIV-related knowledge, attitudes and practices (KAPs) of high school students in Lao People's Democratic Republic (PDR). METHODS:A cross-sectional study on unmarrie...

journal_title：Journal of the International AIDS Society

authors： Thanavanh B,Harun-Or-Rashid M,Kasuya H,Sakamoto J

更新日期：2013-03-11 00:00:00

abstract：INTRODUCTION:People living with HIV (PLHIV) have the right to exercise voluntary choices about their health, including their reproductive health. This commentary discusses the integral role that family planning (FP) plays in helping PLHIV, including those in serodiscordant relationships, achieve conception safely. The ...

journal_title：Journal of the International AIDS Society

authors： Mason J,Medley A,Yeiser S,Nightingale VR,Mani N,Sripipatana T,Abutu A,Johnston B,Watts DH

更新日期：2017-03-08 00:00:00

abstract：INTRODUCTION:HIV infection impairs maintenance of immunological memory, yet few studies of HIV-positive adults receiving 7-valent pneumococcal conjugate vaccine (PCV7) have followed them beyond the first year. We determined and compared the durability of serological responses and the clinical outcomes of HIV-positive a...

journal_title：Journal of the International AIDS Society

authors： Cheng A,Chang SY,Tsai MS,Su YC,Liu WC,Sun HY,Hung CC

更新日期：2016-01-29 00:00:00

abstract：INTRODUCTION:HIV testing is a cornerstone of efforts to combat the HIV epidemic, and testing conducted as part of surveillance provides invaluable data on the spread of infection and the effectiveness of campaigns to reduce the transmission of HIV. However, participation in HIV testing can be low, and if respondents sy...

journal_title：Journal of the International AIDS Society

authors： McGovern ME,Marra G,Radice R,Canning D,Newell ML,Bärnighausen T

更新日期：2015-11-26 00:00:00

abstract：INTRODUCTION:The 48-week interim analysis of the MODAT study showed that confirmed virologic failure (CVF) was more frequent in patients simplifying to ATV/r monotherapy compared to maintaining ATV/r-based triple therapy. The DSMB recommended stopping study enrollment but continuing follow-up of enrolled patients. We p...

journal_title：Journal of the International AIDS Society

authors： Spagnuolo V,Galli L,Bigoloni A,Nozza S,Monforte Ad,Antinori A,Di Biagio A,Rusconi S,Guaraldi G,Di Giambenedetto S,Lazzarin A,Castagna A

更新日期：2014-11-02 00:00:00