The potential impact of new national guidance on primary prevention of cardiovascular disease in people living with HIV.

abstract：BACKGROUND:Diagnosis of primary HIV infection (PHI) has important clinical and public health implications. HAART initiation at this stage remains controversial. METHODS:Our objective was to identify predictors of disease progression among Argentinean seroconverters during the first year of infection, within a multicen...

journal_title：Journal of the International AIDS Society

authors： Socías ME,Sued O,Laufer N,Lázaro ME,Mingrone H,Pryluka D,Remondegui C,Figueroa MI,Cesar C,Gun A,Turk G,Bouzas MB,Kavasery R,Krolewiecki A,Pérez H,Salomón H,Cahn P,Grupo Argentino de Seroconversión Study Group.

更新日期：2011-08-10 00:00:00

abstract：BACKGROUND:The primary objective of this study was to determine the prevalence of neurocognitive impairment among HIV-positive individuals in Botswana, using the International HIV Dementia Scale (IHDS). We also compared performance on the IHDS with performance on tests of verbal learning/memory and processing speed, an...

journal_title：Journal of the International AIDS Society

authors： Lawler K,Mosepele M,Ratcliffe S,Seloilwe E,Steele K,Nthobatsang R,Steenhoff A

更新日期：2010-04-20 00:00:00

abstract：INTRODUCTION:HIV-controllers have the ability to spontaneously maintain viraemia at low or undetectable levels in the absence of antiretroviral treatment. Furthermore, HIV-controllers seem to have a superior capacity to spontaneously clear hepatitis C virus (HCV) compared to non HIV-controllers. Some of these subjects ...

journal_title：Journal of the International AIDS Society

authors： Dominguez-Molina B,Tarancon-Diez L,Milanés-Guisado Y,Genebat M,Resino S,Rodriguez C,Gonzalez-García J,Rallón N,Pernas M,Casado C,Lopez-Galíndez C,León A,Benito JM,García F,Del Romero J,Viciana P,Lopez-Cortes LF,Leal M,

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:The Amsterdam PrEP project is a prospective, open-label demonstration study at a large sexually transmitted infection (STI) clinic. We examined the uptake of PrEP; the baseline characteristics of men who have sex with men (MSM) and transgender persons initiating PrEP; their choices of daily versus event-dr...

journal_title：Journal of the International AIDS Society

authors： Hoornenborg E,Achterbergh RC,van der Loeff MFS,Davidovich U,van der Helm JJ,Hogewoning A,van Duijnhoven YT,Sonder GJ,de Vries HJ,Prins M,Amsterdam PrEP Project team in the HIV Transmission Elimination AMsterdam Initiative.

更新日期：2018-03-01 00:00:00

abstract：INTRODUCTION:There are limited data characterizing the burden of HIV among men who have sex with men (MSM) in Malawi. Epidemiologic research and access to HIV prevention, treatment and care services have been traditionally limited in Malawi by criminalization and stigmatization of same-sex practices. To inform the deve...

journal_title：Journal of the International AIDS Society

authors： Wirtz AL,Jumbe V,Trapence G,Kamba D,Umar E,Ketende S,Berry M,Strömdahl S,Beyrer C,Baral SD

更新日期：2013-12-02 00:00:00

abstract：INTRODUCTION:Vaginal tenofovir (TFV) 1% gel may reduce incident HIV-1 and herpes simplex virus 2 infection. Pregnancy may increase risk of HIV acquisition, and incident HIV in pregnancy potentiates perinatal HIV transmission. Our objective was to investigate the safety and pharmacokinetics of seven days of TFV 1% vagin...

journal_title：Journal of the International AIDS Society

authors： Beigi RH,Noguchi LM,Montgomery E,Biggio J,Hendrix CW,Marzinke MA,Dai JY,Pan J,Kunjara Na Ayudhya R,Schwartz JL,Isaacs K,Piper JM,Watts DH

更新日期：2016-09-21 00:00:00

abstract：INTRODUCTION:Qualitative research on antiretroviral therapy (ART) adherence interventions can provide a deeper understanding of intervention facilitators and barriers. This systematic review aims to synthesize qualitative evidence of interventions for improving ART adherence and to inform patient-centred policymaking. ...

journal_title：Journal of the International AIDS Society

authors： Ma Q,Tso LS,Rich ZC,Hall BJ,Beanland R,Li H,Lackey M,Hu F,Cai W,Doherty M,Tucker JD

更新日期：2016-10-17 00:00:00

abstract：INTRODUCTION:People living with HIV (PLHIV) on antiretroviral therapy (ART) experience high rates of non-communicable diseases (NCDs). These co-morbidities often accumulate and older adults may suffer from multimorbidity. Multimorbidity has been associated with loss of quality of life, polypharmacy, and increased risk ...

journal_title：Journal of the International AIDS Society

authors： Castilho JL,Escuder MM,Veloso V,Gomes JO,Jayathilake K,Ribeiro S,Souza RA,Ikeda ML,de Alencastro PR,Tupinanbas U,Brites C,McGowan CC,Grangeiro A,Grinsztejn B

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Low bone mineral density (BMD) and osteoporosis are prevalent in HIV-infected patients and were associated with HIV infection and tenofovir-containing ART. MATERIALS AND METHODS:The GUSTA study (GUided Simplification with Tropism Assay) is a two-arm, prospective, multicenter, 1:1 randomized controlled tri...

journal_title：Journal of the International AIDS Society

authors： Bianco C,Rossetti B,Gagliardini R,Lamonica S,Fanti L,Lombardi F,Cauda R,Di Giambenedetto S,De Luca A

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Virtually no African country provides HIV prevention services in sex work settings with an adequate scale and intensity. Uncertainty remains about the optimal set of interventions and mode of delivery. METHODS:We systematically reviewed studies reporting interventions for reducing HIV transmission among f...

journal_title：Journal of the International AIDS Society

authors： Chersich MF,Luchters S,Ntaganira I,Gerbase A,Lo YR,Scorgie F,Steen R

更新日期：2013-03-04 00:00:00

abstract：INTRODUCTION:Treatment as prevention has mobilized new opportunities in preventing HIV transmission and has led to bold new UNAIDS targets in testing, treatment coverage and transmission reduction. These will require not only an increase in investment but also a deeper understanding of the dynamics of combining behavio...

journal_title：Journal of the International AIDS Society

authors： Brown G,Reeders D,Dowsett GW,Ellard J,Carman M,Hendry N,Wallace J

更新日期：2015-12-14 00:00:00

abstract：INTRODUCTION:Women living with HIV experience a disproportionate burden of mental health issues. To date, global guidelines contain insufficient guidance on mental health support, particularly regarding perinatal care. The aim of this article is to describe the extent and impact of mental health issues as experienced b...

journal_title：Journal of the International AIDS Society

authors： Orza L,Bewley S,Logie CH,Crone ET,Moroz S,Strachan S,Vazquez M,Welbourn A

更新日期：2015-12-01 00:00:00

abstract：INTRODUCTION:T cell immunoglobulin and mucin domain (Tim) 3 and programmed death 1 (PD-1) are co-inhibitory receptors involved in the so-called T cell exhaustion, and in vivo blockade of these molecules restores T cell dysfunction. High expression of Tim-3 and PD-1 is induced after chronic antigen-specific stimulation ...

journal_title：Journal of the International AIDS Society

authors： Sada-Ovalle I,Ocaña-Guzman R,Pérez-Patrigeón S,Chávez-Galán L,Sierra-Madero J,Torre-Bouscoulet L,Addo MM

更新日期：2015-10-19 00:00:00

abstract：INTRODUCTION:In 2012, the Supreme Court of Canada ruled that people living with HIV (PLWH) must disclose their HIV status to sexual partners prior to sexual activity that poses a "realistic possibility" of HIV transmission for consent to sex to be valid. The Supreme Court deemed that the duty to disclose could be avert...

journal_title：Journal of the International AIDS Society

authors： Patterson SE,Milloy MJ,Ogilvie G,Greene S,Nicholson V,Vonn M,Hogg R,Kaida A

更新日期：2015-12-22 00:00:00

abstract：INTRODUCTION:This was a descriptive non-interventional study in HIV-1-infected patients treated with DRV/r conducted in the clinical setting, with a single-arm prospective design. The primary objective was to collect data on utilization of darunavir/ritonavir (DRV/r) under the conditions described in the marketing auth...

journal_title：Journal of the International AIDS Society

authors： Antinori A,Galli M,Gianotti N,Mussini C,Quirino T,Sterrantino K,Mancusi D,Termini R

更新日期：2014-11-02 00:00:00

abstract：BACKGROUND:In order to maximize the benefits of HIV care and treatment investments in sub-Saharan Africa, programs can broaden to target other diseases amenable to screening and efficient management. We nested cervical cancer screening into family planning clinics at select sites also receiving PEPFAR support for antir...

journal_title：Journal of the International AIDS Society

authors： Moon TD,Silva-Matos C,Cordoso A,Baptista AJ,Sidat M,Vermund SH

更新日期：2012-06-18 00:00:00

abstract：INTRODUCTION:The relative efficacy of different antiretroviral (ART) regimens has been extensively evaluated in the context of clinical trials, using HIV viral load (VL) measurements at pre-specified timepoints after ART onset. However, data from real-life studies using combined longitudinal measurements of cumulative ...

journal_title：Journal of the International AIDS Society

authors： Pascom AR,Pinho RE,Rick F,Veras NM,Perini FB,Meireles MV,Pereira GF,Benzaken AS,Avelino-Silva VI

更新日期：2019-11-01 00:00:00

abstract：INTRODUCTION:Globally, young gay, bisexual and other men who have sex with men (gbMSM) continue to experience disproportionately high rates of HIV and other sexually transmitted and blood-borne infections (STBBIs). As such, there are strong public health imperatives to evaluate innovative prevention, treatment and care...

journal_title：Journal of the International AIDS Society

authors： Knight R,Karamouzian M,Salway T,Gilbert M,Shoveller J

更新日期：2017-11-01 00:00:00

abstract：INTRODUCTION:WHO recommends assisted partner notification (APN) for people living with HIV (PLHIV). These services have not been widely scaled in Central Asia. We describe the results from an APN intervention implemented within a programme focused on PLHIV and people who inject drugs in Kazakhstan, the Kyrgyz Republic ...

journal_title：Journal of the International AIDS Society

authors： Little KM,Kan M,Samoylova O,Rsaldinova A,Saliev D,Ishokov F,Gray R,Hasen NS

更新日期：2019-07-01 00:00:00

abstract：INTRODUCTION:Although individual HIV rapid diagnostic tests (RDTs) show good performance in evaluations conducted by WHO, reports from several African countries highlight potentially significant performance issues. Despite widespread use of RDTs for HIV diagnosis in resource-constrained settings, there has been no syst...

journal_title：Journal of the International AIDS Society

authors： Kosack CS,Page AL,Beelaert G,Benson T,Savane A,Ng'ang'a A,Andre B,Zahinda JB,Shanks L,Fransen K

更新日期：2017-03-24 00:00:00

abstract：INTRODUCTION:Policies for rationing antiretroviral therapy (ART) have been subject to on-going ethical debates. Introduced in Malawi in 2011, Option B+ prioritized HIV-positive pregnant women for lifelong ART regardless of the underlying state of their immune system, shifting the logic of allocation away from medical e...

journal_title：Journal of the International AIDS Society

authors： Yeatman S,Trinitapoli J

更新日期：2017-03-08 00:00:00

abstract：INTRODUCTION:With limited funds available, meeting global health targets requires countries to both mobilize and prioritize their health spending. Within this context, countries have recognized the importance of allocating funds for HIV as efficiently as possible to maximize impact. Over the past six years, the governm...

journal_title：Journal of the International AIDS Society

authors： Stuart RM,Grobicki L,Haghparast-Bidgoli H,Panovska-Griffiths J,Skordis J,Keiser O,Estill J,Baranczuk Z,Kelly SL,Reporter I,Kedziora DJ,Shattock AJ,Petravic J,Hussain SA,Grantham KL,Gray RT,Yap XF,Martin-Hughes R,Bened

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:HIV infection impairs maintenance of immunological memory, yet few studies of HIV-positive adults receiving 7-valent pneumococcal conjugate vaccine (PCV7) have followed them beyond the first year. We determined and compared the durability of serological responses and the clinical outcomes of HIV-positive a...

journal_title：Journal of the International AIDS Society

authors： Cheng A,Chang SY,Tsai MS,Su YC,Liu WC,Sun HY,Hung CC

更新日期：2016-01-29 00:00:00

abstract：INTRODUCTION:Engaging at-risk men in HIV prevention programs and services is a current priority, yet there are few effective ways to identify which men are at highest risk or how to best reach them. In this study we generated multi-factor profiles of HIV acquisition/transmission risk for men in Durban, South Africa, to...

journal_title：Journal of the International AIDS Society

authors： Gottert A,Pulerwitz J,Heck CJ,Cawood C,Mathur S

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:High levels of HIV seroconcordance at the population level reduce the potential for effective HIV transmission. However, the level of HIV seroconcordance is largely unknown among heterosexual couples in sub-Saharan Africa. We aimed to quantify the population level HIV seroconcordance in stable heterosexual...

journal_title：Journal of the International AIDS Society

authors： Kim HY,Harling G,Vandormael A,Tomita A,Cuadros DF,Bärnighausen T,Tanser F

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Since June 2016, the national HIV programme in Malawi has adopted Universal Test and Treat (UTT) guidelines requiring that all persons who test HIV positive will be referred to start antiretroviral therapy (ART). Although there is strong evidence from clinical trials that early initiation of ART leads to r...

journal_title：Journal of the International AIDS Society

authors： Alhaj M,Amberbir A,Singogo E,Banda V,van Lettow M,Matengeni A,Kawalazira G,Theu J,Jagriti MR,Chan AK,van Oosterhout JJ

更新日期：2019-02-01 00:00:00

abstract：INTRODUCTION:Nearly 40 years into the HIV epidemic, the persistence of HIV stigma is a matter of grave urgency. Discrimination (i.e. enacted stigma) in healthcare settings is particularly problematic as it deprives people of critical healthcare services while also discouraging preventive care seeking by confirming fear...

journal_title：Journal of the International AIDS Society

authors： Smith MK,Xu RH,Hunt SL,Wei C,Tucker JD,Tang W,Luo D,Xue H,Wang C,Yang L,Yang B,Li L,Joyner BL Jr,Sylvia SY

更新日期：2020-08-01 00:00:00

abstract：INTRODUCTION:The Robert Koch Institute (RKI) aimed to assess a molecular surveillance strategy based on filter-dried serum spots (DSS) of all newly diagnosed HIV infections in Germany. In 2013, diagnostic laboratories sent DSS to the RKI representing 55% of the newly diagnosed HIV infections reported to the RKI (protec...

journal_title：Journal of the International AIDS Society

authors： Andrea H,Alexandra H,Claudia SH,Ruth Z,Osamah H,Norbert B,Claudia K

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:People living with HIV (PLHIV) have the right to exercise voluntary choices about their health, including their reproductive health. This commentary discusses the integral role that family planning (FP) plays in helping PLHIV, including those in serodiscordant relationships, achieve conception safely. The ...

journal_title：Journal of the International AIDS Society

authors： Mason J,Medley A,Yeiser S,Nightingale VR,Mani N,Sripipatana T,Abutu A,Johnston B,Watts DH

更新日期：2017-03-08 00:00:00

abstract：:The strength of the evidence linking concurrency to HIV epidemic severity in southern and eastern Africa led the Joint United Nations Programme on HIV/AIDS and the Southern African Development Community in 2006 to conclude that high rates of concurrent sexual partnerships, combined with low rates of male circumcision ...

journal_title：Journal of the International AIDS Society

authors： Epstein H,Morris M

更新日期：2011-03-15 00:00:00