How does living with HIV impact on women's mental health? Voices from a global survey.

abstract：BACKGROUND:The majority of new HIV infections are acquired through heterosexual transmission. There is urgent need for prevention methods to compliment behavior change and condom use. Topical microbicide represent a potential strategy for reduction of HIV transmission in women. METHODS:Monthly Colposcopy evaluations w...

journal_title：Journal of the International AIDS Society

authors： Chirenje ZM,Mâsse BR,Maslankowski LA,Ramjee G,Coletti AS,Tembo TN,Magure TM,Soto-Torres L,Kelly C,Hillier S,Karim A

更新日期：2012-08-27 00:00:00

abstract：INTRODUCTION:Low bone mineral density (BMD) and osteoporosis are prevalent in HIV-infected patients and were associated with HIV infection and tenofovir-containing ART. MATERIALS AND METHODS:The GUSTA study (GUided Simplification with Tropism Assay) is a two-arm, prospective, multicenter, 1:1 randomized controlled tri...

journal_title：Journal of the International AIDS Society

authors： Bianco C,Rossetti B,Gagliardini R,Lamonica S,Fanti L,Lombardi F,Cauda R,Di Giambenedetto S,De Luca A

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:While there is a global consensus on monitoring Human Immunodeficiency Virus (HIV) treatment progress, there has been less attention to the degree of consistency of the measurement of HIV prevention programmes-and the global prevention response is not on-track to achieve 2020 goals. In this paper, we asses...

journal_title：Journal of the International AIDS Society

authors： Sekimitsu S,DePasse J,Morrison M,Mahy M,Rice B,Earle K,Daley K,Larson J,Carter A,Garnett GP,Holmes CB

更新日期：2020-12-01 00:00:00

abstract：INTRODUCTION:Lopinavir/ritonavir-based antiretroviral therapy (ART) is recommended for all HIV-infected children less than three years. However, little is known about its field implementation and effectiveness in West Africa. We assessed the 12-month response to lopinavir/ritonavir-based antiretroviral therapy in a coh...

journal_title：Journal of the International AIDS Society

authors： Amani-Bosse C,Dahourou DL,Malateste K,Amorissani-Folquet M,Coulibaly M,Dattez S,Emieme A,Barry M,Rouzioux C,N'gbeche S,Yonaba C,Timité-Konan M,Mea V,Ouédraogo S,Blanche S,Meda N,Seguin-Devaux C,Leroy V

更新日期：2017-04-25 00:00:00

abstract：: The question of whether to initiate ART at higher CD4+ cell counts than currently recommended by World Health Organization (WHO) treatment guidelines received much attention at the XVII International AIDS Conference (AIDS 2008). If studies presented at the conference ultimately lead to a revision of WHO treatment gui...

journal_title：Journal of the International AIDS Society

authors： Mascolini M,Kort R,Gilden D

更新日期：2009-10-06 00:00:00

abstract：BACKGROUND:While the number of HIV-positive patients on antiretroviral therapy (ART) in resource-limited settings has increased dramatically, some patients eligible for treatment do not initiate ART even when it is available to them. Understanding why patients opt out of care, or are unable to opt in, is important to a...

journal_title：Journal of the International AIDS Society

authors： Fox MP,Mazimba A,Seidenberg P,Crooks D,Sikateyo B,Rosen S

更新日期：2010-03-06 00:00:00

abstract：INTRODUCTION:In 2016, the Global Health Sector Strategy (GHSS) on viral hepatitis called for elimination of viral hepatitis as a major public health threat by 2030 (i.e. 90% reduction in incidence and 65% in mortality). In 2017, WHO's first-ever Global Hepatitis Report presented the baseline values for each of the core...

journal_title：Journal of the International AIDS Society

authors： Hutin YJ,Bulterys M,Hirnschall GO

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:High levels of HIV seroconcordance at the population level reduce the potential for effective HIV transmission. However, the level of HIV seroconcordance is largely unknown among heterosexual couples in sub-Saharan Africa. We aimed to quantify the population level HIV seroconcordance in stable heterosexual...

journal_title：Journal of the International AIDS Society

authors： Kim HY,Harling G,Vandormael A,Tomita A,Cuadros DF,Bärnighausen T,Tanser F

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Recent debates on how to achieve an optimal HIV response are dominated by intervention strategies that fail to recognize children's role in the community response to HIV. Whilst formal responses are key to the HIV response, they must recognize and build on indigenous community resources. This study examine...

journal_title：Journal of the International AIDS Society

authors： Skovdal M,Magutshwa-Zitha S,Campbell C,Nyamukapa C,Gregson S

更新日期：2013-02-04 00:00:00

abstract：INTRODUCTION:Cenicriviroc (CVC), a once-daily, dual CCR5/CCR2 co-receptor antagonist, has completed Phase 2b development. CVC demonstrated favourable safety and similar efficacy compared with efavirenz (EFV) in Study 202 (NCT01338883); an ex vivo sub-analysis evaluated treatment effects on HIV entry, measured by intrac...

journal_title：Journal of the International AIDS Society

authors： Kramer V,Hassounah S,Colby-Germinario S,Mesplède T,Lefebvre E,Wainberg M

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:In 2014 the Joint United Nations Programme on HIV/AIDS defined the ambitious 90-90-90 targets for 2020, in which 90% of people living with HIV must be diagnosed, 90% of those diagnosed should be on sustained therapy and 90% of those on therapy should have an undetectable viral load. Children are considered...

journal_title：Journal of the International AIDS Society

authors： Rabie H,Frigati L,Hesseling AC,Garcia-Prats AJ

更新日期：2015-12-02 00:00:00

abstract：:Potent antiretroviral therapy (ART) reduces mortality and morbidity in people living with HIV by reducing viral load and allowing their immune systems to recover. The reduction in viral load soon after starting ART has led to the hypothesis that early and widespread ART could prevent onward transmission and therefore ...

journal_title：Journal of the International AIDS Society

authors： Williams B,Wood R,Dukay V,Delva W,Ginsburg D,Hargrove J,Stander M,Sheneberger R,Montaner J,Welte A

更新日期：2011-07-06 00:00:00

abstract：INTRODUCTION:Mortality among HIV-positive adults awaiting antiretroviral therapy (ART) has previously been found to be high. Here, we compare adolescent pre-ART mortality to that of adults in a public sector HIV care programme in Bulawayo, Zimbabwe. METHODS:In this retrospective cohort study, we compared adolescent pr...

journal_title：Journal of the International AIDS Society

authors： Shroufi A,Ndebele W,Nyathi M,Gunguwo H,Dixon M,Saint-Sauveur JF,Taziwa F,Viñoles MC,Ferrand RA

更新日期：2015-02-23 00:00:00

abstract：BACKGROUND:Young people in southern and eastern Africa remain disproportionately vulnerable to HIV with gender inequalities and livelihood insecurities being key drivers of this. Behavioural HIV prevention interventions have had weak outcomes and a new generation of structural interventions have emerged seeking to chal...

journal_title：Journal of the International AIDS Society

authors： Gibbs A,Willan S,Misselhorn A,Mangoma J

更新日期：2012-06-14 00:00:00

abstract：INTRODUCTION:Safer conception strategies minimize HIV risk during condomless sex to become pregnant. Gaps remain in understanding the acceptability, feasibility and choices HIV-serodiscordant couples make when multiple safer conception options are available. METHODS:We conducted a pilot study of a comprehensive safer ...

journal_title：Journal of the International AIDS Society

authors： Heffron R,Ngure K,Velloza J,Kiptinness C,Quame-Amalgo J,Oluch L,Thuo N,Njoroge J,Momanyi R,Gakuo S,Mbugua S,Morrison S,Haugen H,Chohan B,Celum C,Baeten JM,Mugo N

更新日期：2019-04-01 00:00:00

abstract：INTRODUCTION:Inadequate knowledge, negative attitudes and risky practices are major hindrances to preventing the spread of HIV. This study aimed to assess HIV-related knowledge, attitudes and practices (KAPs) of high school students in Lao People's Democratic Republic (PDR). METHODS:A cross-sectional study on unmarrie...

journal_title：Journal of the International AIDS Society

authors： Thanavanh B,Harun-Or-Rashid M,Kasuya H,Sakamoto J

更新日期：2013-03-11 00:00:00

abstract：INTRODUCTION:In response to the increasing burden of HIV, the Ugandan government has employed different service delivery models since 2004 that aim to reduce costs and remove barriers to accessing HIV care. These models include community-based approaches to delivering antiretroviral therapy (ART) and delegating tasks t...

journal_title：Journal of the International AIDS Society

authors： Vu L,Waliggo S,Zieman B,Jani N,Buzaalirwa L,Okoboi S,Okal J,Borse NN,Kalibala S

更新日期：2016-07-20 00:00:00

abstract：INTRODUCTION:HIV and syphilis testing rates remain low among men who have sex with men (MSM) in low- and middle-income countries (LMICs). Community engagement has been increasingly used to promote HIV testing among key populations in high-income countries, often in settings with stronger civil society. This study aimed...

journal_title：Journal of the International AIDS Society

authors： Zhang TP,Liu C,Han L,Tang W,Mao J,Wong T,Zhang Y,Tang S,Yang B,Wei C,Tucker JD

更新日期：2017-04-03 00:00:00

abstract：INTRODUCTION:A severe healthcare worker shortage in sub-Saharan Africa is inhibiting the expansion of HIV treatment. Task shifting, the transfer of antiretroviral therapy (ART) management and initiation from doctors to nurses and other non-physician clinicians, has been proposed to address this problem. However, many h...

journal_title：Journal of the International AIDS Society

authors： Emdin CA,Chong NJ,Millson PE

更新日期：2013-07-03 00:00:00

abstract：INTRODUCTION:HIV continues to devastate the adolescent population in sub-Saharan Africa (SSA). The complex array of interpersonal, social, structural and system-level obstacles specific to adolescents have slowed progress in prevention and treatment of HIV in this population. The field of implementation science holds p...

journal_title：Journal of the International AIDS Society

authors： Sturke R,Vorkoper S,Bekker LG,Ameyan W,Luo C,Allison S,Walker D,Kapogiannis B,Guay L

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:In the Microbicide Trial Network MTN-003 (VOICE) study, a Phase IIB pre-exposure prophylaxis trial of daily oral or vaginal tenofovir (TFV), product adherence was poor based on pharmacokinetic (PK) drug detection in a random subsample. Here, we sought to compare behavioural and PK measures of adherence and...

journal_title：Journal of the International AIDS Society

authors： van der Straten A,Brown ER,Marrazzo JM,Chirenje MZ,Liu K,Gomez K,Marzinke MA,Piper JM,Hendrix CW,MTN-003 VOICE Protocol Team for Microbicide Trials Network.

更新日期：2016-02-04 00:00:00

abstract：INTRODUCTION:Treatment as prevention has mobilized new opportunities in preventing HIV transmission and has led to bold new UNAIDS targets in testing, treatment coverage and transmission reduction. These will require not only an increase in investment but also a deeper understanding of the dynamics of combining behavio...

journal_title：Journal of the International AIDS Society

authors： Brown G,Reeders D,Dowsett GW,Ellard J,Carman M,Hendry N,Wallace J

更新日期：2015-12-14 00:00:00

abstract：INTRODUCTION:HIV-1-associated CD4+ T-cell depletion is a consequence of uninfected cell death. Nef is one of the viral factors that trigger apoptosis on bystander cells, though the plasma Nef levels do not correlate with Th lymphocytes counts. The aim of our study was to evaluate whether anti-Nef antibodies were involv...

journal_title：Journal of the International AIDS Society

authors： Corró G,Crudeli CM,Rocco CA,Marino SA,Sen L

更新日期：2014-02-14 00:00:00

abstract：INTRODUCTION:Lamivudine (3TC) and emtricitabine (FTC) are considered interchangeable by HIV-1 guidelines in first-line tenofovir/efavirenz (TDF/EFV) and TDF/nevirapine (NVP) combination antiretroviral therapy (cART). Data from trials on equivalence of 3TC and FTC are inconsistent. We examined the effectiveness of 3TC a...

journal_title：Journal of the International AIDS Society

authors： Rokx C,Fibriani A,van de Vijver D,Verbon A,Schutten M,Gras L,Rijnders BJ

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Young women aged 15 to 24 years in sub-Saharan Africa continue to be disproportionately affected by HIV. A growing number of studies have suggested that the practice of transactional sex may in part explain women's heightened risk, but evidence on the association between transactional sex and HIV has not y...

journal_title：Journal of the International AIDS Society

authors： Wamoyi J,Stobeanau K,Bobrova N,Abramsky T,Watts C

更新日期：2016-11-02 00:00:00

abstract：BACKGROUND:Despite the centrality of family in Indian society, relatively little is known about family-based communication concerning sexual behaviour and HIV/AIDS in rural Indian families. To date, very few family-based adolescent HIV-prevention interventions have been developed for rural Indian youth. This study cond...

journal_title：Journal of the International AIDS Society

authors： Soletti AB,Guilamo-Ramos V,Burnette D,Sharma S,Bouris A

更新日期：2009-11-19 00:00:00

abstract：INTRODUCTION:Women living with HIV (WLWH) are reportedly at increased risk of invasive cervical cancer (ICC). WLWH in Denmark attend the National ICC screening program less often than women in the general population. We aimed to estimate the incidence of cervical dysplasia and ICC in WLWH in Denmark. METHODS:We studie...

journal_title：Journal of the International AIDS Society

authors： Thorsteinsson K,Ladelund S,Jensen-Fangel S,Katzenstein TL,Johansen IS,Pedersen G,Junge J,Helleberg M,Storgaard M,Obel N,Lebech AM

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Within monocyte-derived macrophages, HIV-1 accumulates in intracellular virus-containing compartments (VCCs) that are inaccessible to the external environment, which implicate these cells as latently infected HIV-1 reservoirs. During mother-to-child transmission of HIV-1, human placental macrophages (Hofba...

journal_title：Journal of the International AIDS Society

authors： Johnson EL,Chu H,Byrareddy SN,Spearman P,Chakraborty R

更新日期：2015-01-22 00:00:00

abstract：INTRODUCTION:To be used most effectively, pre-exposure prophylaxis (PrEP) should be prioritized to those at high risk of acquisition and would ideally be aligned with time periods of increased exposure. Identifying such time periods is not always straightforward, however. Gaza Province in southern Mozambique is charact...

journal_title：Journal of the International AIDS Society

authors： Cremin I,Morales F,Jewell BL,O'Reilly KR,Hallett TB

更新日期：2015-07-20 00:00:00

abstract：INTRODUCTION:Qualitative research on antiretroviral therapy (ART) adherence interventions can provide a deeper understanding of intervention facilitators and barriers. This systematic review aims to synthesize qualitative evidence of interventions for improving ART adherence and to inform patient-centred policymaking. ...

journal_title：Journal of the International AIDS Society

authors： Ma Q,Tso LS,Rich ZC,Hall BJ,Beanland R,Li H,Lackey M,Hu F,Cai W,Doherty M,Tucker JD

更新日期：2016-10-17 00:00:00