Acceptability of PrEP among HIV negative Portuguese men who have sex with men that attended 2014 Lisbon pride fair.

Abstract:

INTRODUCTION:Consistent use of PrEP reduces HIV transmission from sexual practices amongst men who have sex with men (MSM) up to 92% [1]. Lisbon MSM cohort study estimates point that 59.3% of their participants at entrance (1593 HIV negative MSM enrolled between April 2011 and May 2013) were eligible for PrEP [2], according to the 2014 USA PrEP guidelines [3]. Studies about PrEP acceptability and implementation support policies aimed at increasing and rolling out its use. Hence, the exploratory study about PrEP acceptability in MSM at Lisbon. MATERIALS AND METHODS:A street-based intercept survey, adapted from Mantell et al. study [4], was the one used on MSM attending the 2014 Lisbon pride fair. The survey included socio-demographic data, PrEP awareness and readiness to use it, probability of MSM's social network to also use it, promptness to join PrEP-related studies, type of PrEP warranted and condomless anal sex practice in the last six months. RESULTS:A total of 110 HIV negative Portuguese MSM responded, with a median age of 33% and 84% of them identified themselves as gay. A majority of MSM were unaware of PrEP (59%); those that were aware, had heard of it trough CheckpointLx (31%), internet (22%) or health professionals (20%). 66% were likely or very likely to participate in PrEP-related studies. 57% of MSM were likely or very likely to use PrEP if available and reported that some, if not almost all of their social network, will do it too (70%). Type of PrEP preferred was oral, a pill a day (43%), followed by oral, intermittent intake (32%). Overall 41% of MSM had condomless anal sex practice in the last six months. CONCLUSIONS:In this MSM Portuguese sample, a general willingness to adopt PrEP was predominant, specially the oral daily intake. Forty-one percent of participants had had condomless anal sex practice in the last six months and therefore fitted within the criteria to be on Pre-Exposure Prophylaxis (PrEP), according to MSM Risk Index in 2014 USA PrEP guidelines. PrEP, when available in Portugal, should be a powerful tool for HIV prevention in this key population.

journal_name

J Int AIDS Soc

authors

Rocha LM,Campos MJ,Brito J,Fuertes R,Rojas J,Pinto N,Mendão L,Esteves J

doi

10.7448/IAS.17.4.19734

subject

Has Abstract

pub_date

2014-11-02 00:00:00

pages

19734

issue

4 Suppl 3

issn

1758-2652

pii

19734

journal_volume

17

pub_type

杂志文章
  • Cardiac effects in perinatally HIV-infected and HIV-exposed but uninfected children and adolescents: a view from the United States of America.

    abstract:INTRODUCTION:Human immunodeficiency virus (HIV) infection is a primary cause of acquired heart disease, particularly of accelerated atherosclerosis, symptomatic heart failure, and pulmonary arterial hypertension. Cardiac complications often occur in late-stage HIV infections as prolonged viral infection is becoming mor...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章,评审

    doi:10.7448/IAS.16.1.18597

    authors: Lipshultz SE,Miller TL,Wilkinson JD,Scott GB,Somarriba G,Cochran TR,Fisher SD

    更新日期:2013-06-18 00:00:00

  • Transmitted drug resistance to rilpivirine among antiretroviral-naïve patients living with HIV from northern Poland.

    abstract:INTRODUCTION:Rilpivirine (RPV) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) that was recently approved for the treatment of antiretroviral-naïve individuals with HIV-1 viral load of <100,000 copies/ml. As transmission of the drug resistance mutations to this NNRTI may affect treatment o...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.7448/IAS.17.1.18929

    authors: Parczewski M,Urbańska A,Maciejewska K,Witak-Jȩdra M,Leszczyszyn-Pynka M

    更新日期:2014-04-17 00:00:00

  • Rethinking HIV prevention to prepare for oral PrEP implementation for young African women.

    abstract:INTRODUCTION:HIV incidence remains high among young women in sub-Saharan Africa in spite of scale-up of HIV testing, behavioural interventions, antiretroviral treatment and medical male circumcision. There is a critical need to critique past approaches and learn about the most effective implementation of evidence-based...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.7448/IAS.18.4.20227

    authors: Celum CL,Delany-Moretlwe S,McConnell M,van Rooyen H,Bekker LG,Kurth A,Bukusi E,Desmond C,Morton J,Baeten JM

    更新日期:2015-07-20 00:00:00

  • Effectiveness and durability of darunavir/ritonavir (DRV/r) in DRV/r-experienced HIV-1-infected patients in routine clinical practice.

    abstract:INTRODUCTION:This was a descriptive non-interventional study in HIV-1-infected patients treated with DRV/r conducted in the clinical setting, with a single-arm prospective design. The primary objective was to collect data on utilization of darunavir/ritonavir (DRV/r) under the conditions described in the marketing auth...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.7448/IAS.17.4.19786

    authors: Antinori A,Galli M,Gianotti N,Mussini C,Quirino T,Sterrantino K,Mancusi D,Termini R

    更新日期:2014-11-02 00:00:00

  • Bone mineral density improvement after 48 weeks of switch to maraviroc+darunavir/ritonavir 300/800/100 mg QD, preliminary results of GUSTA study.

    abstract:INTRODUCTION:Low bone mineral density (BMD) and osteoporosis are prevalent in HIV-infected patients and were associated with HIV infection and tenofovir-containing ART. MATERIALS AND METHODS:The GUSTA study (GUided Simplification with Tropism Assay) is a two-arm, prospective, multicenter, 1:1 randomized controlled tri...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.7448/IAS.17.4.19816

    authors: Bianco C,Rossetti B,Gagliardini R,Lamonica S,Fanti L,Lombardi F,Cauda R,Di Giambenedetto S,De Luca A

    更新日期:2014-11-02 00:00:00

  • HIV-1 tat and rev upregulates osteoclast bone resorption.

    abstract:INTRODUCTION:Disruption in bone homeostasis with increased osteoclastic resorption may lead to osteoporosis. HIV tat has been found to increase differentiation of precursor cells into osteoclast (OC) (1). Presence of soluble HIV proteins in virally suppressed HIV patients on ART may drive a bone resorption phenotype. W...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.7448/IAS.17.4.19724

    authors: Chew N,Tan E,Li L,Lim R

    更新日期:2014-11-02 00:00:00

  • Interruptions of antiretroviral therapy in children and adolescents with HIV infection in clinical practice: a retrospective cohort study in the USA.

    abstract:INTRODUCTION:Changes in combination antiretroviral therapy (cART) throughout childhood challenge the continuity of paediatric HIV treatment. This study aimed to evaluate the prevalence of treatment interruption (TI), including lamivudine (3TC) monotherapy, and the relationship of TI to virologic and immunologic paramet...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.7448/IAS.19.1.20936

    authors: Rakhmanina N,Lam KS,Hern J,Young HA,Walters A,Castel AD

    更新日期:2016-10-27 00:00:00

  • What makes orphans in Kigali, Rwanda, non-adherent to antiretroviral therapy? Perspectives of their caregivers.

    abstract:INTRODUCTION:Every year, approximately 260,000 children are infected with HIV in low- and middle-income countries. The timely initiation and high level of maintenance of antiretroviral therapy (ART) are crucial to reducing the suffering of HIV-positive children. We need to develop a better understanding of the backgrou...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.7448/IAS.17.1.19310

    authors: Kikuchi K,Poudel KC,Muganda J,Sato T,Mutabazi V,Muhayimpundu R,Majyambere A,Nyonsenga SP,Sase E,Jimba M

    更新日期:2014-12-03 00:00:00

  • Attitudes of serodiscordant couples towards antiretroviral-based HIV prevention strategies in Kenya: a qualitative study.

    abstract:INTRODUCTION:Transmission in serodiscordant couples (SDCs) accounts for approximately half of all new HIV infections, both in Kenya and the wider sub-Saharan region (1). With evidence to suggest inconsistent condom use within this population (2), the World Health Organization has recommended two new methods of HIV prev...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.7448/IAS.17.4.19563

    authors: Fowler N,Arkell P,Abouyannis M,James C,Roberts L

    更新日期:2014-11-02 00:00:00

  • Access to HIV care in the context of universal test and treat: challenges within the ANRS 12249 TasP cluster-randomized trial in rural South Africa.

    abstract:INTRODUCTION:We aimed to quantify and identify associated factors of linkage to HIV care following home-based HIV counselling and testing (HBHCT) in the ongoing ANRS 12249 treatment-as-prevention (TasP) cluster-randomized trial in rural KwaZulu-Natal, South Africa. METHODS:Individuals ≥16 years were offered HBHCT; tho...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章,随机对照试验

    doi:10.7448/IAS.19.1.20913

    authors: Plazy M,Farouki KE,Iwuji C,Okesola N,Orne-Gliemann J,Larmarange J,Lert F,Newell ML,Dabis F,Dray-Spira R,Anrs 12249 Tasp Study Group.

    更新日期:2016-06-01 00:00:00

  • CNS safety at 48-week of switching to ATV/r plus 3TC or two nucleos(t)ides in HIV-suppressed patients on stable ART: the SALT neurocognitive sub-study.

    abstract:INTRODUCTION:Due to their low CNS penetrance, there are concerns about the capacity of non-conventional PI-based ART (monotherapy and dual therapies) to preserve neurocognitive performance (NP). METHODS:We evaluated the NP change of aviremic participants of the SALT clinical trial (1) switching therapy to dual therapy...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.7448/IAS.17.4.19656

    authors: Valero IP,Pasquau J,Rubio R,Ribero A,Santos J,Sanz J,Mariño A,Crespo M,Hernandez J,Iribarren JA,Gutierrez F,Terron A,Esteban H,Pérez-Molina JA

    更新日期:2014-11-02 00:00:00

  • Treatment as Prevention: unanswered questions and progress to date.

    abstract::Prevention of HIV infection has recently acquired new effective tools, based on the provision of antiretrovirals, to both decrease the "source" of HIV infection and/or to decrease host susceptibility to HIV infection. The milestone concept of using antiretrovirals for prevention has been tested already in the 1990s, t...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.7448/IAS.17.4.19521

    authors: Vella S

    更新日期:2014-11-02 00:00:00

  • Barriers and facilitators to linkage to ART in primary care: a qualitative study of patients and providers in Blantyre, Malawi.

    abstract:INTRODUCTION:Linkage from HIV testing and counselling (HTC) to initiation of antiretroviral therapy (ART) is suboptimal in many national programmes in sub-Saharan Africa, leading to delayed initiation of ART and increased risk of death. Reasons for failure of linkage are poorly understood. METHODS:Semi-structured qual...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.7448/IAS.15.2.18020

    authors: MacPherson P,MacPherson EE,Mwale D,Bertel Squire S,Makombe SD,Corbett EL,Lalloo DG,Desmond N

    更新日期:2012-12-31 00:00:00

  • Community-based approaches for prevention of mother to child transmission in resource-poor settings: a social ecological review.

    abstract:INTRODUCTION:Numerous barriers to optimal uptake of prevention of mother to child transmission (PMTCT) services occur at community level (i.e., outside the healthcare setting). To achieve elimination of paediatric HIV, therefore, interventions must also work within communities to address these barriers and increase ser...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章,评审

    doi:10.7448/IAS.15.4.17373

    authors: Busza J,Walker D,Hairston A,Gable A,Pitter C,Lee S,Katirayi L,Simiyu R,Mpofu D

    更新日期:2012-07-11 00:00:00

  • Efficacy and safety in clinical practice of a rilpivirine, tenofovir and emtricitabine single-tablet regimen in virologically suppressed HIV-positive patients on stable antiretroviral therapy.

    abstract:INTRODUCTION:Switching to a rilpivirine, tenofovir and emtricitabine (RTE) single-tablet regimen (STR) has been evaluated in a limited number of virologically suppressed patients. The aim of this study was to describe clinical outcomes in HIV-positive patients switched from a suppressive antiretroviral regimen to RTE S...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.7448/IAS.18.1.20037

    authors: Gianotti N,Poli A,Nozza S,Spagnuolo V,Tambussi G,Bossolasco S,Cinque P,Maillard M,Cernuschi M,Galli L,Lazzarin A,Castagna A

    更新日期:2015-07-30 00:00:00

  • Special theme on HIV and disability - time for closer bonds.

    abstract:: With the success of antiretrovirals and increased access to this lifesaving treatment, the life expectancy of people living with HIV has been substantially increased and, in many instances, is comparable to that of the general population. However, HIV infection, as well as its treatment, can cause physical, psycholog...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.1186/1758-2652-2-1

    authors: Heidari S,Kippax S

    更新日期:2009-11-09 00:00:00

  • HIV prevention among transgender women in Latin America: implementation, gaps and challenges.

    abstract:INTRODUCTION:Transgender women are the population most vulnerable to HIV in Latin America, with prevalence between 18 and 38%. Although the region has improved antiretroviral coverage, there is an urgent need to strengthen HIV prevention for key populations to meet regional targets set by governments. We conducted an a...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章,评审

    doi:10.7448/IAS.19.3.20799

    authors: Silva-Santisteban A,Eng S,de la Iglesia G,Falistocco C,Mazin R

    更新日期:2016-07-17 00:00:00

  • Perspectives of US women participating in a candidate PrEP study: adherence, acceptability and future use intentions.

    abstract:INTRODUCTION:Limited data exist on acceptability of candidate pre-exposure prophylaxis (PrEP) regimens among US women. We evaluated PrEP experiences, attitudes and future use intentions among sexually active women who completed the US-based HIV Prevention Trials Network 069/AIDS Clinical Trials Group 5305 study. METHO...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/jia2.25247

    authors: Amico KR,Ramirez C,Caplan MR,Montgomery BE,Stewart J,Hodder S,Swaminathan S,Wang J,Darden-Tabb NY,McCauley M,Mayer KH,Wilkin T,Landovitz RJ,Gulick R,Adimora AA,HPTN 069\/A5305 Study Team and HPTN Women at Risk Committee.

    更新日期:2019-03-01 00:00:00

  • Transactional sex and risk for HIV infection in sub-Saharan Africa: a systematic review and meta-analysis.

    abstract:INTRODUCTION:Young women aged 15 to 24 years in sub-Saharan Africa continue to be disproportionately affected by HIV. A growing number of studies have suggested that the practice of transactional sex may in part explain women's heightened risk, but evidence on the association between transactional sex and HIV has not y...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章,meta分析,评审

    doi:10.7448/IAS.19.1.20992

    authors: Wamoyi J,Stobeanau K,Bobrova N,Abramsky T,Watts C

    更新日期:2016-11-02 00:00:00

  • Viral load assay performs comparably to early infant diagnosis assay to diagnose infants with HIV in Mozambique: a prospective observational study.

    abstract:INTRODUCTION:Viral load testing is essential to manage HIV disease, especially in infants and children. Early infant diagnosis is performed using nucleic-acid testing in children under 18 months. Resource-limited health systems face severe challenges to scale-up both viral load and early infant diagnosis to unprecedent...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.1002/jia2.25422

    authors: Vubil A,Nhachigule C,Loquiha O,Meggi B,Mabunda N,Bollinger T,Sacks JA,Jani I,Vojnov L

    更新日期:2020-01-01 00:00:00

  • An analysis of the implementation of PEPFAR's anti-prostitution pledge and its implications for successful HIV prevention among organizations working with sex workers.

    abstract:INTRODUCTION:Since 2003, US government funding to address the HIV and AIDS pandemic has been subject to an anti-prostitution clause. Simultaneously, the efficacy of some HIV prevention efforts for sex work in areas receiving US government funding has diminished. This article seeks to explain why. METHODS:This analysis...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.7448/IAS.16.1.17354

    authors: Ditmore MH,Allman D

    更新日期:2013-03-28 00:00:00

  • Creating HIV risk profiles for men in South Africa: a latent class approach using cross-sectional survey data.

    abstract:INTRODUCTION:Engaging at-risk men in HIV prevention programs and services is a current priority, yet there are few effective ways to identify which men are at highest risk or how to best reach them. In this study we generated multi-factor profiles of HIV acquisition/transmission risk for men in Durban, South Africa, to...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.1002/jia2.25518

    authors: Gottert A,Pulerwitz J,Heck CJ,Cawood C,Mathur S

    更新日期:2020-06-01 00:00:00

  • Eliminating hepatitis C virus as a public health threat among HIV-positive men who have sex with men: a multi-modelling approach to understand differences in sexual risk behaviour.

    abstract:INTRODUCTION:Outbreaks of hepatitis C virus (HCV) infections among HIV-positive men who have sex with men (MSM) have been observed globally. Using a multi-modelling approach we estimate the time and number of direct-acting antiviral treatment courses required to achieve an 80% reduction in HCV prevalence among HIV-posi...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.1002/jia2.25059

    authors: Scott N,Stoové M,Wilson DP,Keiser O,El-Hayek C,Doyle J,Hellard M

    更新日期:2018-01-01 00:00:00

  • India-US collaboration to prevent adolescent HIV infection: the feasibility of a family-based HIV-prevention intervention for rural Indian youth.

    abstract:BACKGROUND:Despite the centrality of family in Indian society, relatively little is known about family-based communication concerning sexual behaviour and HIV/AIDS in rural Indian families. To date, very few family-based adolescent HIV-prevention interventions have been developed for rural Indian youth. This study cond...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.1186/1758-2652-12-35

    authors: Soletti AB,Guilamo-Ramos V,Burnette D,Sharma S,Bouris A

    更新日期:2009-11-19 00:00:00

  • Analysis of transmitted drug resistance and HIV-1 subtypes using dried serum spots of recently HIV-infected individuals in 2013 in Germany.

    abstract:INTRODUCTION:The Robert Koch Institute (RKI) aimed to assess a molecular surveillance strategy based on filter-dried serum spots (DSS) of all newly diagnosed HIV infections in Germany. In 2013, diagnostic laboratories sent DSS to the RKI representing 55% of the newly diagnosed HIV infections reported to the RKI (protec...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.7448/IAS.17.4.19670

    authors: Andrea H,Alexandra H,Claudia SH,Ruth Z,Osamah H,Norbert B,Claudia K

    更新日期:2014-11-02 00:00:00

  • Seasonal PrEP for partners of migrant miners in southern Mozambique: a highly focused PrEP intervention.

    abstract:INTRODUCTION:To be used most effectively, pre-exposure prophylaxis (PrEP) should be prioritized to those at high risk of acquisition and would ideally be aligned with time periods of increased exposure. Identifying such time periods is not always straightforward, however. Gaza Province in southern Mozambique is charact...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.7448/IAS.18.4.19946

    authors: Cremin I,Morales F,Jewell BL,O'Reilly KR,Hallett TB

    更新日期:2015-07-20 00:00:00

  • Estimating the costs and cost-effectiveness of HIV self-testing among men who have sex with men, United States.

    abstract:INTRODUCTION:HIV testing is an essential prerequisite for accessing treatment with antiretroviral therapy or prevention using pre-exposure prophylaxis. Internet distribution of HIV self-tests is a novel approach, and data on the programmatic cost of this approach are limited. We analyse the costs and cost-effectiveness...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/jia2.25445

    authors: Shrestha RK,Chavez PR,Noble M,Sansom SL,Sullivan PS,Mermin JH,MacGowan RJ

    更新日期:2020-01-01 00:00:00

  • HIV knowledge trends during an era of rapid antiretroviral therapy scale-up: an analysis of 33 sub-Saharan African countries.

    abstract:INTRODUCTION:Population-level improvements in knowledge about HIV may reduce the stigma attached to HIV and ensure maximal uptake of HIV prevention initiatives. The extent to which levels of HIV knowledge in the general population of sub-Saharan Africa have changed in the current era of antiretroviral therapy (ART) sca...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.1002/jia2.25169

    authors: Chan BT,Tsai AC

    更新日期:2018-07-01 00:00:00

  • Knowledge, attitudes and practices regarding HIV/AIDS among male high school students in Lao People's Democratic Republic.

    abstract:INTRODUCTION:Inadequate knowledge, negative attitudes and risky practices are major hindrances to preventing the spread of HIV. This study aimed to assess HIV-related knowledge, attitudes and practices (KAPs) of high school students in Lao People's Democratic Republic (PDR). METHODS:A cross-sectional study on unmarrie...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.7448/IAS.16.1.17387

    authors: Thanavanh B,Harun-Or-Rashid M,Kasuya H,Sakamoto J

    更新日期:2013-03-11 00:00:00

  • Socio-economic status and time trends associated with early ART initiation following primary HIV infection in Montreal, Canada: 1996 to 2015.

    abstract:INTRODUCTION:Guidelines regarding antiretroviral therapy (ART) initiation in HIV infection have varied over time, with the 2015 World Health Organization recommendation suggesting ART initiation at the time of diagnosis regardless of CD4 T-cell counts. Herein, we investigated the influence of socio-demographic and clin...

    journal_title:Journal of the International AIDS Society

    pub_type: 杂志文章

    doi:10.1002/jia2.25034

    authors: Mehraj V,Cox J,Lebouché B,Costiniuk C,Cao W,Li T,Ponte R,Thomas R,Szabo J,Baril JG,Trottier B,Côté P,LeBlanc R,Bruneau J,Tremblay C,Routy JP,Montreal Primary HIV-Infection Study Group.

    更新日期:2018-02-01 00:00:00