HIV prevention among transgender women in Latin America: implementation, gaps and challenges.

abstract：INTRODUCTION:Inadequate knowledge, negative attitudes and risky practices are major hindrances to preventing the spread of HIV. This study aimed to assess HIV-related knowledge, attitudes and practices (KAPs) of high school students in Lao People's Democratic Republic (PDR). METHODS:A cross-sectional study on unmarrie...

journal_title：Journal of the International AIDS Society

authors： Thanavanh B,Harun-Or-Rashid M,Kasuya H,Sakamoto J

更新日期：2013-03-11 00:00:00

abstract：INTRODUCTION:Although RTS as HIV Diagnosis was considered cost effectiveness [1], overall budget may be unaffordable for some countries. We explore Incremental cost per NDHI associated with different TS. MATERIALS AND METHODS:From a health care perspective, using direct costs and Euros currency, we calculated budget a...

journal_title：Journal of the International AIDS Society

authors： Gomez-Ayerbe C,Elías MJ,Muriel A,Elías PP,Cano A,Diaz A,Moreno A,Casado JL,Santos C,Martinez-Colubi M,Uranga A,Dronda F,Moreno S

更新日期：2014-11-02 00:00:00

abstract：:Improved knowledge, better programmes and policies, effective treatment and other scientific developments have reduced levels of new HIV infections globally. Evidence shows that programmes that prevent HIV among sex workers and their clients are most successful when all aspects of vulnerability are addressed and when ...

journal_title：Journal of the International AIDS Society

authors： Overs C,Loff B

更新日期：2013-08-29 00:00:00

abstract：INTRODUCTION:Since June 2016, the national HIV programme in Malawi has adopted Universal Test and Treat (UTT) guidelines requiring that all persons who test HIV positive will be referred to start antiretroviral therapy (ART). Although there is strong evidence from clinical trials that early initiation of ART leads to r...

journal_title：Journal of the International AIDS Society

authors： Alhaj M,Amberbir A,Singogo E,Banda V,van Lettow M,Matengeni A,Kawalazira G,Theu J,Jagriti MR,Chan AK,van Oosterhout JJ

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Micronutrient deficiencies compromise the survival of HIV-infected children in low-income countries. We assessed the effect of multiple micronutrient supplementation on the mortality of HIV-infected children in Uganda. METHODS:In a randomized, controlled trial, 847 children aged one to five years and attend...

journal_title：Journal of the International AIDS Society

authors： Ndeezi G,Tylleskär T,Ndugwa CM,Tumwine JK

更新日期：2010-06-03 00:00:00

abstract：INTRODUCTION:Limited data exist on acceptability of candidate pre-exposure prophylaxis (PrEP) regimens among US women. We evaluated PrEP experiences, attitudes and future use intentions among sexually active women who completed the US-based HIV Prevention Trials Network 069/AIDS Clinical Trials Group 5305 study. METHO...

journal_title：Journal of the International AIDS Society

authors： Amico KR,Ramirez C,Caplan MR,Montgomery BE,Stewart J,Hodder S,Swaminathan S,Wang J,Darden-Tabb NY,McCauley M,Mayer KH,Wilkin T,Landovitz RJ,Gulick R,Adimora AA,HPTN 069\/A5305 Study Team and HPTN Women at Risk Committee.

更新日期：2019-03-01 00:00:00

abstract：INTRODUCTION:Lamivudine (3TC) and emtricitabine (FTC) are considered interchangeable by HIV-1 guidelines in first-line tenofovir/efavirenz (TDF/EFV) and TDF/nevirapine (NVP) combination antiretroviral therapy (cART). Data from trials on equivalence of 3TC and FTC are inconsistent. We examined the effectiveness of 3TC a...

journal_title：Journal of the International AIDS Society

authors： Rokx C,Fibriani A,van de Vijver D,Verbon A,Schutten M,Gras L,Rijnders BJ

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Transmission in serodiscordant couples (SDCs) accounts for approximately half of all new HIV infections, both in Kenya and the wider sub-Saharan region (1). With evidence to suggest inconsistent condom use within this population (2), the World Health Organization has recommended two new methods of HIV prev...

journal_title：Journal of the International AIDS Society

authors： Fowler N,Arkell P,Abouyannis M,James C,Roberts L

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Evidence suggests that people who inject drugs often begin their drug use and injecting practices in adolescence, yet there are limited data available on the HIV epidemic and the responses for this population. The comprehensive package of interventions for the prevention, treatment and care of HIV infectio...

journal_title：Journal of the International AIDS Society

authors： Krug A,Hildebrand M,Sun N

更新日期：2015-02-26 00:00:00

abstract：INTRODUCTION:The Robert Koch Institute (RKI) aimed to assess a molecular surveillance strategy based on filter-dried serum spots (DSS) of all newly diagnosed HIV infections in Germany. In 2013, diagnostic laboratories sent DSS to the RKI representing 55% of the newly diagnosed HIV infections reported to the RKI (protec...

journal_title：Journal of the International AIDS Society

authors： Andrea H,Alexandra H,Claudia SH,Ruth Z,Osamah H,Norbert B,Claudia K

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:To be used most effectively, pre-exposure prophylaxis (PrEP) should be prioritized to those at high risk of acquisition and would ideally be aligned with time periods of increased exposure. Identifying such time periods is not always straightforward, however. Gaza Province in southern Mozambique is charact...

journal_title：Journal of the International AIDS Society

authors： Cremin I,Morales F,Jewell BL,O'Reilly KR,Hallett TB

更新日期：2015-07-20 00:00:00

abstract：INTRODUCTION:Mortality among HIV-positive adults awaiting antiretroviral therapy (ART) has previously been found to be high. Here, we compare adolescent pre-ART mortality to that of adults in a public sector HIV care programme in Bulawayo, Zimbabwe. METHODS:In this retrospective cohort study, we compared adolescent pr...

journal_title：Journal of the International AIDS Society

authors： Shroufi A,Ndebele W,Nyathi M,Gunguwo H,Dixon M,Saint-Sauveur JF,Taziwa F,Viñoles MC,Ferrand RA

更新日期：2015-02-23 00:00:00

abstract：INTRODUCTION:Optimal adherence to antiretroviral therapy is closely related with suppression of the HIV viral load in plasma, slowing disease progression and decreasing HIV transmission rates. Despite its importance, the estimated proportion of people living with HIV in Latin America and the Caribbean with optimal adhe...

journal_title：Journal of the International AIDS Society

authors： Costa JM,Torres TS,Coelho LE,Luz PM

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:The HIV epidemics in the Caribbean, Central America and South America (CCASA), Eastern Europe (EE) and Asia and Pacific (AP) regions are diverse epidemics affecting different key populations in predominantly middle-income countries. This narrative review describes the populations of HIV-positive youth appr...

journal_title：Journal of the International AIDS Society

authors： Bailey H,Cruz MLS,Songtaweesin WN,Puthanakit T

更新日期：2017-05-16 00:00:00

abstract：INTRODUCTION:Safer conception strategies minimize HIV risk during condomless sex to become pregnant. Gaps remain in understanding the acceptability, feasibility and choices HIV-serodiscordant couples make when multiple safer conception options are available. METHODS:We conducted a pilot study of a comprehensive safer ...

journal_title：Journal of the International AIDS Society

authors： Heffron R,Ngure K,Velloza J,Kiptinness C,Quame-Amalgo J,Oluch L,Thuo N,Njoroge J,Momanyi R,Gakuo S,Mbugua S,Morrison S,Haugen H,Chohan B,Celum C,Baeten JM,Mugo N

更新日期：2019-04-01 00:00:00

abstract：INTRODUCTION:Dolutegravir (DTG) is an HIV integrase strand transfer inhibitor approved for use in combination with other antiretrovirals for the treatment of HIV-infection in adults and adolescents. Metformin is a drug frequently used in diabetic HIV-infected patients, which requires titration to optimize dosing. In vi...

journal_title：Journal of the International AIDS Society

authors： Zong J,Borland J,Jerva F,Wynne B,Choukour M,Song I

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Injecting drug use (IDU) is associated with tuberculosis but few data are available from low-income settings. We examined IDU in relation to active and latent tuberculosis (LTBI) among HIV-positive individuals in Indonesia, which has a high burden of tuberculosis and a rapidly growing HIV epidemic strongly...

journal_title：Journal of the International AIDS Society

authors： Meijerink H,Wisaksana R,Lestari M,Meilana I,Chaidir L,van der Ven AJ,Alisjahbana B,van Crevel R

更新日期：2015-02-16 00:00:00

abstract：INTRODUCTION:Worldwide, 71 million people are infected with hepatitis C virus (HCV), which, without treatment, can lead to liver failure or hepatocellular carcinoma. HCV co-infection increases liver- and AIDS-related morbidity and mortality among HIV-positive people, despite ART. A 12-week course of HCV direct-acting a...

journal_title：Journal of the International AIDS Society

authors： Grillon C,Krishtel PR,Mellouk O,Basenko A,Freeman J,Mendão L,Andrieux-Meyer I,Morin S

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:In the Microbicide Trial Network MTN-003 (VOICE) study, a Phase IIB pre-exposure prophylaxis trial of daily oral or vaginal tenofovir (TFV), product adherence was poor based on pharmacokinetic (PK) drug detection in a random subsample. Here, we sought to compare behavioural and PK measures of adherence and...

journal_title：Journal of the International AIDS Society

authors： van der Straten A,Brown ER,Marrazzo JM,Chirenje MZ,Liu K,Gomez K,Marzinke MA,Piper JM,Hendrix CW,MTN-003 VOICE Protocol Team for Microbicide Trials Network.

更新日期：2016-02-04 00:00:00

abstract：INTRODUCTION:The relative efficacy of different antiretroviral (ART) regimens has been extensively evaluated in the context of clinical trials, using HIV viral load (VL) measurements at pre-specified timepoints after ART onset. However, data from real-life studies using combined longitudinal measurements of cumulative ...

journal_title：Journal of the International AIDS Society

authors： Pascom AR,Pinho RE,Rick F,Veras NM,Perini FB,Meireles MV,Pereira GF,Benzaken AS,Avelino-Silva VI

更新日期：2019-11-01 00:00:00

abstract：INTRODUCTION:A severe healthcare worker shortage in sub-Saharan Africa is inhibiting the expansion of HIV treatment. Task shifting, the transfer of antiretroviral therapy (ART) management and initiation from doctors to nurses and other non-physician clinicians, has been proposed to address this problem. However, many h...

journal_title：Journal of the International AIDS Society

authors： Emdin CA,Chong NJ,Millson PE

更新日期：2013-07-03 00:00:00

abstract：INTRODUCTION:Global HIV-1 prevalence is 35.3 million [1]; women comprise >50% of those infected. The majority of women may lack regular care and only one-fourth are virologically suppressed [2]. ELLA is a cross-sectional, non-interventional study conducted across Europe, Latin America, Canada and Asia that describes ba...

journal_title：Journal of the International AIDS Society

authors： Baran R,Mulcahy F,Krznaric I,Monforte Ad,Samarina A,Xi H,Cassetti I,Madruga JV,Zachry W,van Wyk J,Martinez M

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Antiretroviral therapy (ART) substantially improves the health of people living with HIV and contributes to preventing new infections. While HIV incidence is decreasing in most regions, the epidemic in eastern Europe continues to rise, as new infections currently outnumber the rate of ART initiation. In th...

journal_title：Journal of the International AIDS Society

authors： Mallitt KA,Grigoryan SR,Papoyan AS,Wand HC,Wilson DP

更新日期：2014-08-04 00:00:00

abstract：INTRODUCTION:Young women aged 15 to 24 years in sub-Saharan Africa continue to be disproportionately affected by HIV. A growing number of studies have suggested that the practice of transactional sex may in part explain women's heightened risk, but evidence on the association between transactional sex and HIV has not y...

journal_title：Journal of the International AIDS Society

authors： Wamoyi J,Stobeanau K,Bobrova N,Abramsky T,Watts C

更新日期：2016-11-02 00:00:00

abstract：INTRODUCTION:Preventive therapy is essential for reducing tuberculosis (TB) burden among people living with HIV (PLWH) in high-burden settings. Short-course preventive therapy regimens, such as three-month weekly rifapentine and isoniazid (3HP) and one-month daily rifapentine and isoniazid (1HP), may help facilitate up...

journal_title：Journal of the International AIDS Society

authors： Ferguson O,Jo Y,Pennington J,Johnson K,Chaisson RE,Churchyard G,Dowdy D

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:The majority of new HIV infections are acquired through heterosexual transmission. There is urgent need for prevention methods to compliment behavior change and condom use. Topical microbicide represent a potential strategy for reduction of HIV transmission in women. METHODS:Monthly Colposcopy evaluations w...

journal_title：Journal of the International AIDS Society

authors： Chirenje ZM,Mâsse BR,Maslankowski LA,Ramjee G,Coletti AS,Tembo TN,Magure TM,Soto-Torres L,Kelly C,Hillier S,Karim A

更新日期：2012-08-27 00:00:00

abstract：INTRODUCTION:The Good Participatory Practice (GPP): Guidelines for Biomedical HIV Prevention Trials, second edition (2011) were developed to provide clinical trial sponsors and implementers with a formal stakeholder engagement framework. As one of the largest African research institutes, Wits Reproductive Health and HI...

journal_title：Journal of the International AIDS Society

authors： Baron D,Essien T,Pato S,Magongo M,Mbandazayo N,Scorgie F,Rees H,Delany-Moretlwe S

更新日期：2018-10-01 00:00:00

abstract：INTRODUCTION:In 2016, the Global Health Sector Strategy (GHSS) on viral hepatitis called for elimination of viral hepatitis as a major public health threat by 2030 (i.e. 90% reduction in incidence and 65% in mortality). In 2017, WHO's first-ever Global Hepatitis Report presented the baseline values for each of the core...

journal_title：Journal of the International AIDS Society

authors： Hutin YJ,Bulterys M,Hirnschall GO

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:HIV incidence remains high among young women in sub-Saharan Africa in spite of scale-up of HIV testing, behavioural interventions, antiretroviral treatment and medical male circumcision. There is a critical need to critique past approaches and learn about the most effective implementation of evidence-based...

journal_title：Journal of the International AIDS Society

authors： Celum CL,Delany-Moretlwe S,McConnell M,van Rooyen H,Bekker LG,Kurth A,Bukusi E,Desmond C,Morton J,Baeten JM

更新日期：2015-07-20 00:00:00

abstract：INTRODUCTION:In 2012, the Supreme Court of Canada ruled that people living with HIV (PLWH) must disclose their HIV status to sexual partners prior to sexual activity that poses a "realistic possibility" of HIV transmission for consent to sex to be valid. The Supreme Court deemed that the duty to disclose could be avert...

journal_title：Journal of the International AIDS Society

authors： Patterson SE,Milloy MJ,Ogilvie G,Greene S,Nicholson V,Vonn M,Hogg R,Kaida A

更新日期：2015-12-22 00:00:00