Barriers and facilitators to linkage to ART in primary care: a qualitative study of patients and providers in Blantyre, Malawi.

abstract：INTRODUCTION:There is great interest for integrating care for non-communicable diseases (NCDs) into routine HIV services in sub-Saharan Africa (SSA) due to the steady rise of the number of people who are ageing with HIV. Suggested health system approaches for intervening on these comorbidities have mostly been normativ...

journal_title：Journal of the International AIDS Society

authors： Kintu A,Sando D,Okello S,Mutungi G,Guwatudde D,Menzies NA,Danaei G,Verguet S

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:HIV-1 viral escape in the cerebrospinal fluid (CSF) despite viral suppression in plasma is rare [1,2]. We describe the case of a 50-year-old HIV-1 infected patient who was diagnosed with HIV-1 in 1995. Antiretroviral therapy (ART) was started in 1998 with a CD4 T cell count of 71 cells/ìL and HIV-viremia o...

journal_title：Journal of the International AIDS Society

authors： Béguelin C,Vázquez M,Bertschi M,Yerly S,de Jong D,Rauch A,Cusini A

更新日期：2014-11-02 00:00:00

abstract：:Potent antiretroviral therapy (ART) reduces mortality and morbidity in people living with HIV by reducing viral load and allowing their immune systems to recover. The reduction in viral load soon after starting ART has led to the hypothesis that early and widespread ART could prevent onward transmission and therefore ...

journal_title：Journal of the International AIDS Society

authors： Williams B,Wood R,Dukay V,Delva W,Ginsburg D,Hargrove J,Stander M,Sheneberger R,Montaner J,Welte A

更新日期：2011-07-06 00:00:00

abstract：INTRODUCTION:The Good Participatory Practice (GPP): Guidelines for Biomedical HIV Prevention Trials, second edition (2011) were developed to provide clinical trial sponsors and implementers with a formal stakeholder engagement framework. As one of the largest African research institutes, Wits Reproductive Health and HI...

journal_title：Journal of the International AIDS Society

authors： Baron D,Essien T,Pato S,Magongo M,Mbandazayo N,Scorgie F,Rees H,Delany-Moretlwe S

更新日期：2018-10-01 00:00:00

abstract：INTRODUCTION:T cell immunoglobulin and mucin domain (Tim) 3 and programmed death 1 (PD-1) are co-inhibitory receptors involved in the so-called T cell exhaustion, and in vivo blockade of these molecules restores T cell dysfunction. High expression of Tim-3 and PD-1 is induced after chronic antigen-specific stimulation ...

journal_title：Journal of the International AIDS Society

authors： Sada-Ovalle I,Ocaña-Guzman R,Pérez-Patrigeón S,Chávez-Galán L,Sierra-Madero J,Torre-Bouscoulet L,Addo MM

更新日期：2015-10-19 00:00:00

abstract：INTRODUCTION:The Amsterdam PrEP project is a prospective, open-label demonstration study at a large sexually transmitted infection (STI) clinic. We examined the uptake of PrEP; the baseline characteristics of men who have sex with men (MSM) and transgender persons initiating PrEP; their choices of daily versus event-dr...

journal_title：Journal of the International AIDS Society

authors： Hoornenborg E,Achterbergh RC,van der Loeff MFS,Davidovich U,van der Helm JJ,Hogewoning A,van Duijnhoven YT,Sonder GJ,de Vries HJ,Prins M,Amsterdam PrEP Project team in the HIV Transmission Elimination AMsterdam Initiative.

更新日期：2018-03-01 00:00:00

abstract：INTRODUCTION:Routes of transmission and reasons for HIV testing are important epidemiologic data to analyze the epidemic and to tailor the response to AIDS. The aim of this study was to analyze reasons for testing and transmission ways of HIV among recently diagnosed HIV patients registered in the multicenter HIV-TR co...

journal_title：Journal of the International AIDS Society

authors： Dokuzoguz B,Korten V,Gökengin D,Fincanci M,Yildirmak T,Kes UN,Tasdelen Fisgin N,Inan D,Eraksoy H,Akalin H

更新日期：2014-11-02 00:00:00

abstract：: The HIV/AIDS epidemic continues to be a major issue facing Botswana, with overall adult HIV prevalence estimated to be 25.7 percent in 2007. This paper estimates the cost and impact of the draft Ministry of Health male circumcision strategy using the UNAIDS/WHO Decision-Makers' Programme Planning Tool (DMPPT). Demogr...

journal_title：Journal of the International AIDS Society

authors： Bollinger LA,Stover J,Musuka G,Fidzani B,Moeti T,Busang L

更新日期：2009-05-27 00:00:00

abstract：INTRODUCTION:Women living with HIV (WLWH) are reportedly at increased risk of invasive cervical cancer (ICC). WLWH in Denmark attend the National ICC screening program less often than women in the general population. We aimed to estimate the incidence of cervical dysplasia and ICC in WLWH in Denmark. METHODS:We studie...

journal_title：Journal of the International AIDS Society

authors： Thorsteinsson K,Ladelund S,Jensen-Fangel S,Katzenstein TL,Johansen IS,Pedersen G,Junge J,Helleberg M,Storgaard M,Obel N,Lebech AM

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:People living with HIV (PLHIV) on antiretroviral therapy (ART) experience high rates of non-communicable diseases (NCDs). These co-morbidities often accumulate and older adults may suffer from multimorbidity. Multimorbidity has been associated with loss of quality of life, polypharmacy, and increased risk ...

journal_title：Journal of the International AIDS Society

authors： Castilho JL,Escuder MM,Veloso V,Gomes JO,Jayathilake K,Ribeiro S,Souza RA,Ikeda ML,de Alencastro PR,Tupinanbas U,Brites C,McGowan CC,Grangeiro A,Grinsztejn B

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Cenicriviroc (CVC), a once-daily, dual CCR5/CCR2 co-receptor antagonist, has completed Phase 2b development. CVC demonstrated favourable safety and similar efficacy compared with efavirenz (EFV) in Study 202 (NCT01338883); an ex vivo sub-analysis evaluated treatment effects on HIV entry, measured by intrac...

journal_title：Journal of the International AIDS Society

authors： Kramer V,Hassounah S,Colby-Germinario S,Mesplède T,Lefebvre E,Wainberg M

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Achieving UNAIDS 90-90-90 targets is a crucial step towards ending the AIDS epidemic. Many countries have published estimates of care cascades, although often with methodological limitations. We describe an approach that used the national HIV registry as a starting-point to determine the HIV care cascade a...

journal_title：Journal of the International AIDS Society

authors： Ho ZJM,Huang F,Wong CS,Chua L,Ma S,Chen MI,Lee VJ

更新日期：2019-07-01 00:00:00

abstract：INTRODUCTION:Lamivudine (3TC) and emtricitabine (FTC) are considered interchangeable by HIV-1 guidelines in first-line tenofovir/efavirenz (TDF/EFV) and TDF/nevirapine (NVP) combination antiretroviral therapy (cART). Data from trials on equivalence of 3TC and FTC are inconsistent. We examined the effectiveness of 3TC a...

journal_title：Journal of the International AIDS Society

authors： Rokx C,Fibriani A,van de Vijver D,Verbon A,Schutten M,Gras L,Rijnders BJ

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Although hepatitis C virus (HCV) screening is recommended for all HIV-infected patients initiating antiretroviral therapy, data on epidemiologic characteristics of HCV infection in resource-limited settings are scarce. METHODS:We searched PubMed and EMBASE for studies assessing the prevalence of HCV infec...

journal_title：Journal of the International AIDS Society

authors： Azevedo TC,Zwahlen M,Rauch A,Egger M,Wandeler G

更新日期：2016-06-09 00:00:00

abstract：INTRODUCTION:Identifying appropriate pre-exposure prophylaxis (PrEP) candidates is a challenge in planning for the safe and effective roll-out of this strategy. We explored the use of a validated HIV risk screening tool, HIV Incidence Risk Index for Men who have Sex with Men (HIRI-MSM), to identify "optimal" candidates...

journal_title：Journal of the International AIDS Society

authors： Wilton J,Kain T,Fowler S,Hart TA,Grennan T,Maxwell J,Tan DH

更新日期：2016-06-03 00:00:00

abstract：INTRODUCTION:Current healthcare systems fail to provide adequate HIV services to men. In Zambia, 25% of adult men living with HIV were unaware of their HIV status in 2018, and 12% of those who were unaware of their HIV statu were not receiving antiretroviral therapy (ART) due to pervasive barriers to HIV testing servic...

journal_title：Journal of the International AIDS Society

authors： Mwango LK,Stafford KA,Blanco NC,Lavoie MC,Mujansi M,Nyirongo N,Tembo K,Sakala H,Chipukuma J,Phiri B,Nzangwa C,Mwandila S,Nkwemu KC,Saadani A,Mwila A,Herce ME,Claassen CW

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:Guidelines regarding antiretroviral therapy (ART) initiation in HIV infection have varied over time, with the 2015 World Health Organization recommendation suggesting ART initiation at the time of diagnosis regardless of CD4 T-cell counts. Herein, we investigated the influence of socio-demographic and clin...

journal_title：Journal of the International AIDS Society

authors： Mehraj V,Cox J,Lebouché B,Costiniuk C,Cao W,Li T,Ponte R,Thomas R,Szabo J,Baril JG,Trottier B,Côté P,LeBlanc R,Bruneau J,Tremblay C,Routy JP,Montreal Primary HIV-Infection Study Group.

更新日期：2018-02-01 00:00:00

abstract：INTRODUCTION:This descriptive, non-interventional study on HIV-1-infected patients treated with DRV/r in the usual clinical setting, with a single-arm prospective observational design, collected data on utilization of darunavir/ritonavir (DRV/r) under the conditions described in marketing authorization in usual clinica...

journal_title：Journal of the International AIDS Society

authors： Antinori A,Borderi M,Cauda R,Bini T,Chirianni A,Squillace N,Mancusi D,Termini R

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:A severe healthcare worker shortage in sub-Saharan Africa is inhibiting the expansion of HIV treatment. Task shifting, the transfer of antiretroviral therapy (ART) management and initiation from doctors to nurses and other non-physician clinicians, has been proposed to address this problem. However, many h...

journal_title：Journal of the International AIDS Society

authors： Emdin CA,Chong NJ,Millson PE

更新日期：2013-07-03 00:00:00

abstract：INTRODUCTION:Inadequate knowledge, negative attitudes and risky practices are major hindrances to preventing the spread of HIV. This study aimed to assess HIV-related knowledge, attitudes and practices (KAPs) of high school students in Lao People's Democratic Republic (PDR). METHODS:A cross-sectional study on unmarrie...

journal_title：Journal of the International AIDS Society

authors： Thanavanh B,Harun-Or-Rashid M,Kasuya H,Sakamoto J

更新日期：2013-03-11 00:00:00

abstract：INTRODUCTION:Older adults living with HIV (OALHIV; ≥50 years) who use drugs face unique needs and challenges that compromise their health and wellbeing due to the structural and environmental barriers they experience, in addition to being disproportionately affected by comorbidities. Nevertheless, research on this popu...

journal_title：Journal of the International AIDS Society

authors： Chayama KL,Ng C,McNeil R

更新日期：2020-08-01 00:00:00

abstract：INTRODUCTION:HIV continues to devastate the adolescent population in sub-Saharan Africa (SSA). The complex array of interpersonal, social, structural and system-level obstacles specific to adolescents have slowed progress in prevention and treatment of HIV in this population. The field of implementation science holds p...

journal_title：Journal of the International AIDS Society

authors： Sturke R,Vorkoper S,Bekker LG,Ameyan W,Luo C,Allison S,Walker D,Kapogiannis B,Guay L

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:Population-level improvements in knowledge about HIV may reduce the stigma attached to HIV and ensure maximal uptake of HIV prevention initiatives. The extent to which levels of HIV knowledge in the general population of sub-Saharan Africa have changed in the current era of antiretroviral therapy (ART) sca...

journal_title：Journal of the International AIDS Society

authors： Chan BT,Tsai AC

更新日期：2018-07-01 00:00:00

abstract：INTRODUCTION:The HIV Strategy in New South Wales (NSW) Australia aims to virtually eliminate HIV transmission by 2020. We estimated the 2016 HIV diagnosis and care cascade for the state of NSW, with a focus on introducing population-based data to improve data quality and assess progress towards the UNAIDS 90-90-90 targ...

journal_title：Journal of the International AIDS Society

authors： Keen P,Gray RT,Telfer B,Guy R,Schmidt HM,Whittaker B,Holden J,Holt M,Kelleher A,Wilson D,Callander D,Cooper DA,Prestage G,Selvey C,Grulich AE,NSW HIV Prevention Partnership Project.

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:The relative efficacy of different antiretroviral (ART) regimens has been extensively evaluated in the context of clinical trials, using HIV viral load (VL) measurements at pre-specified timepoints after ART onset. However, data from real-life studies using combined longitudinal measurements of cumulative ...

journal_title：Journal of the International AIDS Society

authors： Pascom AR,Pinho RE,Rick F,Veras NM,Perini FB,Meireles MV,Pereira GF,Benzaken AS,Avelino-Silva VI

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:The primary objective of this study was to determine the prevalence of neurocognitive impairment among HIV-positive individuals in Botswana, using the International HIV Dementia Scale (IHDS). We also compared performance on the IHDS with performance on tests of verbal learning/memory and processing speed, an...

journal_title：Journal of the International AIDS Society

authors： Lawler K,Mosepele M,Ratcliffe S,Seloilwe E,Steele K,Nthobatsang R,Steenhoff A

更新日期：2010-04-20 00:00:00

abstract：INTRODUCTION:Lipodystrophy is still a matter of concern in HIV+ patients receiving ART. However, long-term fat change in patients taking non-thymidine regimens is not well known. MATERIALS AND METHODS:A prospective ongoing fat change assessment including clinical evaluation and dexa scans (Hologic QDR 4500) is being c...

journal_title：Journal of the International AIDS Society

authors： Ferrer E,Navarro A,Curto J,Medina P,Rozas N,Barrera G,Saumoy M,Tiraboschi JM,Gomez C,Podzamczer D

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Mortality among HIV-positive adults awaiting antiretroviral therapy (ART) has previously been found to be high. Here, we compare adolescent pre-ART mortality to that of adults in a public sector HIV care programme in Bulawayo, Zimbabwe. METHODS:In this retrospective cohort study, we compared adolescent pr...

journal_title：Journal of the International AIDS Society

authors： Shroufi A,Ndebele W,Nyathi M,Gunguwo H,Dixon M,Saint-Sauveur JF,Taziwa F,Viñoles MC,Ferrand RA

更新日期：2015-02-23 00:00:00

abstract：INTRODUCTION:A key objective of combined antiretroviral therapy (cART) is to reach and maintain high CD4 cell counts to provide long-term protection against AIDS-defining opportunistic infections and malignancies, as well as other comorbidities. However, a high proportion of patients present late for care. Our objectiv...

journal_title：Journal of the International AIDS Society

authors： Costagliola D,Lacombe JM,Ghosn J,Delaugerre C,Pialoux G,Cuzin L,Launay O,Ménard A,de Truchis P,Mary-Krause M,Weiss L,Delfraissy JF

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Human immunodeficiency virus (HIV) infection is a primary cause of acquired heart disease, particularly of accelerated atherosclerosis, symptomatic heart failure, and pulmonary arterial hypertension. Cardiac complications often occur in late-stage HIV infections as prolonged viral infection is becoming mor...

journal_title：Journal of the International AIDS Society

authors： Lipshultz SE,Miller TL,Wilkinson JD,Scott GB,Somarriba G,Cochran TR,Fisher SD

更新日期：2013-06-18 00:00:00