Chronic nicotine pretreatment is sufficient to upregulate α4* nicotinic receptors and increase oral nicotine self-administration in mice.

abstract：BACKGROUND:Better treatments for schizophrenia are urgently needed. The therapeutic use of the nitric oxide (NO)-donor sodium nitroprusside (SNP) in patients with schizophrenia has shown promising results. The role of NO in schizophrenia is still unclear, and NO modulation is unexplored in ketamine (KET) animal models ...

journal_title：BMC neuroscience

authors： Kandratavicius L,Balista PA,Wolf DC,Abrao J,Evora PR,Rodrigues AJ,Chaves C,Maia-de-Oliveira JP,Leite JP,Dursun SM,Baker GB,Guimaraes FS,Hallak JE

更新日期：2015-03-07 00:00:00

abstract：:Following the publication of this article [1], it has been noted by the authors that an image of the same cell nuclei has been used in error twice, in Fig. 8, parts A and B. These images are redundant in this figure as the images in parts D and E show Wnt3a treated and control cells stained with both Hoechst 33342 (as...

journal_title：BMC neuroscience

authors： Hooper C,Sainz-Fuertes R,Lynham S,Hye A,Killick R,Warley A,Bolondi C,Pocock J,Lovestone S

更新日期：2020-03-06 00:00:00

abstract：BACKGROUND:Excitatory transmitting mechanisms are proving to play a critical role on neuronal homeostasis conditions of facultative hibernators such as the Syrian golden hamster. Indeed works have shown that the glutamatergic system of the main olfactory brain station (amygdala) is capable of controlling thermoregulato...

journal_title：BMC neuroscience

authors： Alò R,Avolio E,Carelli A,Facciolo RM,Canonaco M

更新日期：2011-01-20 00:00:00

abstract：BACKGROUND:In this study, we examined the effects of cyclophosphamide, methothrexate, and 5-Fluorouracil (CMF) drug combination on various aspects of learning and memory. We also examined the effects of CMF on cell proliferation and chromatin remodeling as possible underlying mechanisms to explain chemotherapy-associat...

journal_title：BMC neuroscience

authors： Briones TL,Woods J

更新日期：2011-12-09 00:00:00

abstract：BACKGROUND:The optic nerve is a pure white matter central nervous system (CNS) tract with an isolated blood supply, and is widely used in physiological studies of white matter response to various insults. We examined the gene expression profile of human optic nerve (ON) and, through the NEIBANK online resource, to prov...

journal_title：BMC neuroscience

authors： Bernstein SL,Guo Y,Peterson K,Wistow G

更新日期：2009-09-24 00:00:00

abstract：BACKGROUND:Parkinson's disease (PD) is a neurological disorder characterized by the degeneration of nigrostriatal dopaminergic systems. Free radicals induced by oxidative stress are involved in the mechanisms of cell death in PD. This study clarifies the neuroprotective effects of edaravone (MCI-186, 3-methyl-1-phenyl-...

journal_title：BMC neuroscience

authors： Yuan WJ,Yasuhara T,Shingo T,Muraoka K,Agari T,Kameda M,Uozumi T,Tajiri N,Morimoto T,Jing M,Baba T,Wang F,Leung H,Matsui T,Miyoshi Y,Date I

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:The olfactory neuroepithelium lines the upper nasal cavity and is in direct contact with the external environment and the olfactory bulbs. The ability to self-renew throughout life and the reproducible recovery after injury, make it a model tissue to study mechanisms underlying neurogenesis. In this study, X...

journal_title：BMC neuroscience

authors： Cunha C,Hort Y,Shine J,Doyle KL

更新日期：2012-10-31 00:00:00

abstract：BACKGROUND:The anesthetic drug ketamine (KT) has been reported to be an abused drug and fatal cases have been observed in polydrug users. In the present study, considering the possibility of KT-enhanced toxic effects of other drugs, and KT-induced promotion of an overdose without making the subject aware of the danger ...

journal_title：BMC neuroscience

authors： Hayase T,Yamamoto Y,Yamamoto K

更新日期：2006-03-16 00:00:00

abstract：BACKGROUND:To date, functional imaging studies of treatment-induced recovery from chronic aphasia only assessed short-term treatment effects after intensive language training. In the present study, we show with functional magnetic resonance imaging (fMRI), that different brain regions may be involved in immediate versu...

journal_title：BMC neuroscience

authors： Menke R,Meinzer M,Kugel H,Deppe M,Baumgärtner A,Schiffbauer H,Thomas M,Kramer K,Lohmann H,Flöel A,Knecht S,Breitenstein C

更新日期：2009-09-22 00:00:00

abstract：BACKGROUND:To determine whether early imitative responses fade out following the maturation of attentional mechanisms, the relationship between primitive imitation behaviors and the development of attention was examined in 4-month-old infants. They were divided into high and low imitators, based on an index of imitatio...

journal_title：BMC neuroscience

authors： Nakagawa A,Sukigara M,Benga O

更新日期：2003-12-24 00:00:00

abstract：BACKGROUND:Previous studies showed that anodal transcranial DC stimulation (tDCS) applied to the primary motor cortex of the affected hemisphere (M1affected hemisphere) after subcortical stroke transiently improves performance of complex tasks that mimic activities of daily living (ADL). It is not known if relatively s...

journal_title：BMC neuroscience

authors： Hummel FC,Voller B,Celnik P,Floel A,Giraux P,Gerloff C,Cohen LG

更新日期：2006-11-03 00:00:00

abstract：BACKGROUND:Astrocytes are responsible for a broad range of functions that maintain homeostasis in the brain. However, their response to the pro-inflammatory cytokines released by activated microglia in various neurological pathologies may exacerbate neurodegenerative processes. Accumulating evidence suggests that omega...

journal_title：BMC neuroscience

authors： Zgórzyńska E,Stulczewski D,Dziedzic B,Su KP,Walczewska A

更新日期：2021-01-27 00:00:00

abstract：BACKGROUND:The processing of verbal fluency tasks relies on the coordinated activity of a number of brain areas, particularly in the frontal and temporal lobes of the left hemisphere. Recent studies using functional magnetic resonance imaging (fMRI) to study the neural networks subserving verbal fluency functions have ...

journal_title：BMC neuroscience

authors： Wagner S,Sebastian A,Lieb K,Tüscher O,Tadić A

更新日期：2014-01-24 00:00:00

abstract：BACKGROUND:Empathy refers to the ability to recognise and share emotions with others. Several research groups have recognised observational fear in mice as a useful behavioural model for assessing their ability to empathise. However, in these observation systems, it remains unclear whether the observer mouse truly reco...

journal_title：BMC neuroscience

authors： Ueno H,Suemitsu S,Murakami S,Kitamura N,Wani K,Takahashi Y,Matsumoto Y,Okamoto M,Ishihara T

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:The aim of this study was to assess the distribution of key SNARE proteins in glutamatergic and GABAergic synapses of the adult rat cerebellar cortex using light microscopy immunohistochemical techniques. Analysis was made of co-localizations of vGluT-1 and vGluT-2, vesicular transporters of glutamate and ma...

journal_title：BMC neuroscience

authors： Benagiano V,Lorusso L,Flace P,Girolamo F,Rizzi A,Bosco L,Cagiano R,Nico B,Ribatti D,Ambrosi G

更新日期：2011-11-17 00:00:00

abstract：BACKGROUND:Post-stroke hyperglycemia appears to be associated with poor outcome from stroke, greater mortality, and reduced functional recovery. Focal cerebral ischemia data support that neural stem cells (NSCs) play an important role in post-ischemic repair. Here we sought to evaluate the negative effects of hyperglyc...

journal_title：BMC neuroscience

authors： Chen J,Guo Y,Cheng W,Chen R,Liu T,Chen Z,Tan S

更新日期：2013-03-04 00:00:00

abstract：BACKGROUND:To examine which language function depends on early experience, the present study compared deaf native signers, deaf non-native signers and hearing German native speakers while processing German sentences. The participants watched simple written sentences while event-related potentials (ERPs) were recorded. ...

journal_title：BMC neuroscience

authors： Skotara N,Salden U,Kügow M,Hänel-Faulhaber B,Röder B

更新日期：2012-05-03 00:00:00

abstract：BACKGROUND:10 Hz electroencephalographic (EEG) alpha rhythms correlate with memory performance. Alpha and memory decline in older people. We wished to test if alpha-like EEG activity contributes to memory formation. Flicker can elicit alpha-like EEG activity. We tested if alpha-frequency flicker enhances memory in olde...

journal_title：BMC neuroscience

authors： Williams J,Ramaswamy D,Oulhaj A

更新日期：2006-03-05 00:00:00

abstract：BACKGROUND:The function of synaptotagmins (syt) in Ca2+-dependent transmitter release has been attributed primarily to Ca2+-dependent isoforms such as syt I. Recently, syt IV, an inducible Ca2+-independent isoform has been implicated in transmitter release. We postulated that the effects of syt IV on transmitter releas...

journal_title：BMC neuroscience

authors： Moore-Dotson JM,Papke JB,Harkins AB

更新日期：2010-08-24 00:00:00

abstract：BACKGROUND:Subjective tinnitus is characterized by an auditory phantom perception in the absence of any physical sound source. Consequently, in a quiet environment, tinnitus patients differ from control participants because they constantly perceive a sound whereas controls do not. We hypothesized that this difference i...

journal_title：BMC neuroscience

authors： Schlee W,Hartmann T,Langguth B,Weisz N

更新日期：2009-02-19 00:00:00

abstract：BACKGROUND:Functional magnetic resonance imaging (fMRI) in white matter has long been considered controversial. Recently, this viewpoint has been challenged by an emerging body of evidence demonstrating white matter activation in the corpus callosum. The current study aimed to determine whether white matter activation ...

journal_title：BMC neuroscience

authors： Gawryluk JR,Mazerolle EL,Brewer KD,Beyea SD,D'Arcy RC

更新日期：2011-06-14 00:00:00

abstract：BACKGROUND:Evoked potentials have been proposed to result from phase-locking of electroencephalographic (EEG) activities within specific frequency bands. However, the respective contribution of phasic activity and phase resetting of ongoing EEG oscillation remains largely debated. We here applied the EEGlab procedure i...

journal_title：BMC neuroscience

authors： Cheron G,Cebolla AM,De Saedeleer C,Bengoetxea A,Leurs F,Leroy A,Dan B

更新日期：2007-09-18 00:00:00

abstract：BACKGROUND:After unilateral cervical cord lesion at the C7/C8 border interrupting the dorsolateral funiculus in adult monkeys, neutralization of Nogo-A using a specific monoclonal antibody promoted sprouting of corticospinal (CS) axons rostral and caudal to the lesion and, in parallel, improved functional recovery. In ...

journal_title：BMC neuroscience

authors： Beaud ML,Schmidlin E,Wannier T,Freund P,Bloch J,Mir A,Schwab ME,Rouiller EM

更新日期：2008-01-14 00:00:00

abstract：BACKGROUND:Previous studies associate lipid peroxidation with long-term memory (LTM) failure in a gastropod model (Lymnaea stagnalis) of associative learning and memory. This process involves activation of Phospholipase A2 (PLA2), an enzyme mediating the release of fatty acids such as arachidonic acid that form the pre...

journal_title：BMC neuroscience

authors： Hermann PM,Park D,Beaulieu E,Wildering WC

更新日期：2013-08-06 00:00:00

abstract：BACKGROUND:Inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, known as statins, are commonly used as cholesterol-lowering drugs. During the past decade, evidence has emerged that statins also have neuroprotective effects. Research in the retina has shown that simvastatin, a commonly used statin, increases A...

journal_title：BMC neuroscience

authors： Brand Y,Setz C,Levano S,Listyo A,Chavez E,Pak K,Sung M,Radojevic V,Ryan AF,Bodmer D

更新日期：2011-11-14 00:00:00

abstract：BACKGROUND:As development proceeds the human embryo attains an ever more complex three dimensional (3D) structure. Analyzing the gene expression patterns that underlie these changes and interpreting their significance depends on identifying the anatomical structures to which they map and following these patterns in dev...

journal_title：BMC neuroscience

authors： Kerwin J,Scott M,Sharpe J,Puelles L,Robson SC,Martínez-de-la-Torre M,Ferran JL,Feng G,Baldock R,Strachan T,Davidson D,Lindsay S

更新日期：2004-08-06 00:00:00

abstract：BACKGROUND:This work examines the central nervous system distribution of virus-labeled neurons from the rat urinary bladder and the prostate simultaneously within the same tissue sections. Two immunohistochemically distinct pseudorabies virus strains were simultaneously injected into male Sprague Dawley rats (approxima...

journal_title：BMC neuroscience

authors： Nadelhaft I,Miranda-Sousa AJ,Vera PL

更新日期：2002-07-12 00:00:00

abstract：BACKGROUND:Given the reported inverse association between light and depressive mood, ambient light may also be associated with some of the brain regions in healthy subjects. The present study aims to investigate the effects of ambient light on glucose metabolism in the brain. We used the data of 28 healthy participants...

journal_title：BMC neuroscience

authors： Hirakawa H,Terao T,Hatano K,Kohno K,Ishii N

更新日期：2018-07-24 00:00:00

abstract：BACKGROUND:The zitter (zi/zi) rat, a loss-of-function mutant of the glycosylated transmembrane protein attractin (atrn), exhibits widespread age-dependent spongiform degeneration, hypomyelination, and abnormal metabolism of reactive oxygen species (ROS) in the brain. To date, the mechanisms underlying these phenotypes ...

journal_title：BMC neuroscience

authors： Sakakibara S,Nakadate K,Ookawara S,Ueda S

更新日期：2008-04-05 00:00:00

abstract：BACKGROUND:Tone languages such as Thai and Mandarin Chinese use differences in fundamental frequency (F0, pitch) to distinguish lexical meaning. Previous behavioral studies have shown that native speakers of a non-tone language have difficulty discriminating among tone contrasts and are sensitive to different F0 dimens...

journal_title：BMC neuroscience

authors： Kaan E,Barkley CM,Bao M,Wayland R

更新日期：2008-06-23 00:00:00