Abstract:
OBJECTIVES:Pseudotumours (abnormal peri-prosthetic soft-tissue reactions) following metal-on-metal hip resurfacing arthroplasty (MoMHRA) have been associated with elevated metal ion levels, suggesting that excessive wear may occur due to edge-loading of these MoM implants. This study aimed to quantify in vivo edge-loading in MoMHRA patients with and without pseudotumours during functional activities. METHODS:The duration and magnitude of edge-loading in vivo was quantified during functional activities by combining the dynamic hip joint segment contact force calculated from the three-dimensional (3D) motion analysis system with the 3D reconstruction of orientation of the acetabular component and each patient's specific hip joint centre, based on CT scans. RESULTS:Edge-loading in the hips with pseudotumours occurred with a four-fold increase in duration and magnitude of force compared with the hips without pseudotumours (p = 0.02). CONCLUSIONS:The study provides the first in vivo evidence to support that edge-loading is an important mechanism that leads to localised excessive wear (edge-wear), with subsequent elevation of metal ion levels in MoMHRA patients with pseudotumours.
journal_name
Bone Joint Resjournal_title
Bone & joint researchauthors
Kwon YM,Mellon SJ,Monk P,Murray DW,Gill HSdoi
10.1302/2046-3758.14.2000019subject
Has Abstractpub_date
2012-04-01 00:00:00pages
42-9issue
4issn
2046-3758pii
2000019journal_volume
1pub_type
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journal_title:Bone & joint research
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journal_title:Bone & joint research
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更新日期:2013-09-10 00:00:00
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journal_title:Bone & joint research
pub_type: 杂志文章
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更新日期:2013-09-16 00:00:00
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journal_title:Bone & joint research
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pub_type: 杂志文章
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