In vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours.

Abstract:

OBJECTIVES:Pseudotumours (abnormal peri-prosthetic soft-tissue reactions) following metal-on-metal hip resurfacing arthroplasty (MoMHRA) have been associated with elevated metal ion levels, suggesting that excessive wear may occur due to edge-loading of these MoM implants. This study aimed to quantify in vivo edge-loading in MoMHRA patients with and without pseudotumours during functional activities. METHODS:The duration and magnitude of edge-loading in vivo was quantified during functional activities by combining the dynamic hip joint segment contact force calculated from the three-dimensional (3D) motion analysis system with the 3D reconstruction of orientation of the acetabular component and each patient's specific hip joint centre, based on CT scans. RESULTS:Edge-loading in the hips with pseudotumours occurred with a four-fold increase in duration and magnitude of force compared with the hips without pseudotumours (p = 0.02). CONCLUSIONS:The study provides the first in vivo evidence to support that edge-loading is an important mechanism that leads to localised excessive wear (edge-wear), with subsequent elevation of metal ion levels in MoMHRA patients with pseudotumours.

journal_name

Bone Joint Res

journal_title

Bone & joint research

authors

Kwon YM,Mellon SJ,Monk P,Murray DW,Gill HS

doi

10.1302/2046-3758.14.2000019

subject

Has Abstract

pub_date

2012-04-01 00:00:00

pages

42-9

issue

4

issn

2046-3758

pii

2000019

journal_volume

1

pub_type

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