Abstract:
OBJECTIVES:We aimed to examine the characteristics of deep venous flow in the leg in a cast and the effects of a wearable neuromuscular stimulator (geko; FirstKind Ltd) and also to explore the participants' tolerance of the stimulator. METHODS:This is an open-label physiological study on ten healthy volunteers. Duplex ultrasonography of the superficial femoral vein measured normal flow and cross-sectional area in the standing and supine positions (with the lower limb initially horizontal and then elevated). Flow measurements were repeated during activation of the geko stimulator placed over the peroneal nerve. The process was repeated after the application of a below-knee cast. Participants evaluated discomfort using a questionnaire (verbal rating score) and a scoring index (visual analogue scale). RESULTS:The geko device was effective in significantly increasing venous blood flow in the lower limb both with a plaster cast (mean difference 11.5 cm/sec(-1); p = 0.001 to 0.13) and without a plaster cast (mean difference 7.7 cm/sec(-1); p = 0.001 to 0.75). Posture also had a significant effect on peak venous blood flow when the cast was on and the geko inactive (p = 0.003 to 0.69), although these differences were less pronounced than the effect of the geko (mean difference 3.1 cm/sec(-1) (-6.5 to 10)). The geko device was well tolerated, with participants generally reporting only mild discomfort using the device. CONCLUSION:The geko device increases venous blood flow in the lower limb, offering a potential mechanical thromboprolylaxis for patients in a cast. Cite this article: Bone Joint Res 2013;2:179-85.
journal_name
Bone Joint Resjournal_title
Bone & joint researchauthors
Warwick DJ,Shaikh A,Gadola S,Stokes M,Worsley P,Bain D,Tucker AT,Gadola SDdoi
10.1302/2046-3758.29.2000176subject
Has Abstractpub_date
2013-09-02 00:00:00pages
179-85issue
9issn
2046-3758pii
2/9/179journal_volume
2pub_type
杂志文章abstract:Objectives:We investigated the reliability of the cobalt-chromium (CoCr) synovial joint fluid ratio (JFR) in identifying the presence of a severe aseptic lymphocyte-dominated vasculitis-associated lesion (ALVAL) response and/or suboptimal taper performance (SOTP) following metal-on-metal (MoM) hip arthroplasty. We then...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.83.BJR-2018-0049.R1
更新日期:2019-04-02 00:00:00
abstract:AIMS:Treatment of chronic osteomyelitis (COM) for young patients remains a challenge. Large bone deficiencies secondary to COM can be treated using induced membrane technique (IMT). However, it is unclear which type of bone graft is optimal. The goal of the study was to determine the clinical effectiveness of bone marr...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.101.BJR-2020-0229.R1
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVES:In order to ensure safety of the cell-based therapy for bone regeneration, we examined in vivo biodistribution of locally or systemically transplanted osteoblast-like cells generated from bone marrow (BM) derived mononuclear cells. METHODS:BM cells obtained from a total of 13 Sprague-Dawley (SD) green fluor...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.33.2000257
更新日期:2014-03-20 00:00:00
abstract:Objectives:Different criteria for assessing the reduction quality of trochanteric fractures have been reported. The Baumgaertner reduction quality criteria (BRQC) are relatively common and the Chang reduction quality criteria (CRQC) are relatively new. The objectives of the current study were to compare the reliability...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.810.BJR-2019-0032.R1
更新日期:2019-11-02 00:00:00
abstract:OBJECTIVES:As tumours of bone and soft tissue are rare, multicentre prospective collaboration is essential for meaningful research and evidence-based advances in patient care. The aim of this study was to identify barriers and facilitators encountered in large-scale collaborative research by orthopaedic oncological sur...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.65.BJR-2016-0192.R1
更新日期:2017-05-01 00:00:00
abstract::The treatment of osteochondral lesions and osteoarthritis remains an ongoing clinical challenge in orthopaedics. This review examines the current research in the fields of cartilage regeneration, osteochondral defect treatment, and biological joint resurfacing, and reports on the results of clinical and pre-clinical s...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.29.2000189
更新日期:2013-09-16 00:00:00
abstract:Aims:Commonly performed unicompartmental knee arthroplasty (UKA) is not designed for the lateral compartment. Additionally, the anatomical medial and lateral tibial plateaus have asymmetrical geometries, with a slightly dished medial plateau and a convex lateral plateau. Therefore, this study aims to investigate the na...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.812.BJR-2019-0114.R1
更新日期:2020-01-08 00:00:00
abstract:Aims:To evaluate graft healing of decellularized porcine superflexor tendon (pSFT) xenograft in an ovine anterior cruciate ligament (ACL) reconstruction model using two femoral fixation devices. Also, to determine if pSFT allows functional recovery of gait as compared with the preoperative measurements. Methods:A tota...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.96.BJR-2020-0030.R2
更新日期:2020-07-23 00:00:00
abstract:AIMS:This study aimed to investigate the effect of solute carrier family 20 member 2 (SLC20A2) gene mutation (identified from a hereditary multiple exostoses family) on chondrocyte proliferation and differentiation. METHODS:ATDC5 chondrocytes were cultured in insulin-transferrin-selenium medium to induce differentiati...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.911.BJR-2020-0112.R1
更新日期:2020-11-01 00:00:00
abstract:Aims:Induction heating is a noninvasive, nonantibiotic treatment modality that can potentially be used to cause thermal damage to the bacterial biofilm on the metal implant surface. The purpose of this study was to determine the effectiveness of induction heating on killing Staphylococcus epidermidis from biofilm and t...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.94.BJR-2019-0274.R1
更新日期:2020-05-16 00:00:00
abstract:OBJECTIVES:This study aimed to characterise and qualitatively grade the severity of the corrosion particles released into the hip joint following taper corrosion. METHODS:The 26 cases examined were CoC/ABG Modular (n = 13) and ASR/SROM (n = 13). Blood serum metal ion levels were collected before and after revision sur...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.59.2000507
更新日期:2016-09-01 00:00:00
abstract:Objectives:The aim of this study was to investigate the biomechanical effect of the anterolateral ligament (ALL), anterior cruciate ligament (ACL), or both ALL and ACL on kinematics under dynamic loading conditions using dynamic simulation subject-specific knee models. Methods:Five subject-specific musculoskeletal mod...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.811.BJR-2019-0103.R1
更新日期:2019-12-03 00:00:00
abstract:OBJECTIVES:To investigate the differences of open reduction and internal fixation (ORIF) of complex AO Type C distal radius fractures between two different models of a single implant type. METHODS:A total of 136 patients who received either a 2.4 mm (n = 61) or 3.5 mm (n = 75) distal radius locking compression plate (...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.16.2000008
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVES:Lengthening osteotomies of the calcaneus in children are in general grafted with bone from the iliac crest. Artificial bone grafts have been introduced, however, their structural and clinical durability has not been documented. Radiostereometric analysis (RSA) is a very accurate and precise method for measur...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.45.2000292
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVES:Local corticosteroid infiltration is a common practice of treatment for lateral epicondylitis. In recent studies no statistically significant or clinically relevant results in favour of corticosteroid injections were found. The injection of autologous blood has been reported to be effective for both intermed...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.18.2000095
更新日期:2012-08-01 00:00:00
abstract:Objectives:Recently, the field of tissue engineering has made numerous advances towards achieving artificial tendon substitutes with excellent mechanical and histological properties, and has had some promising experimental results. The purpose of this systematic review is to assess the efficacy of tissue engineering in...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.74.BJR-2017-0326
更新日期:2018-05-05 00:00:00
abstract::Cartilage repair in terms of replacement, or regeneration of damaged or diseased articular cartilage with functional tissue, is the 'holy grail' of joint surgery. A wide spectrum of strategies for cartilage repair currently exists and several of these techniques have been reported to be associated with successful clin...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.34.2000238
更新日期:2014-04-02 00:00:00
abstract:OBJECTIVES:Pseudotumours (abnormal peri-prosthetic soft-tissue reactions) following metal-on-metal hip resurfacing arthroplasty (MoMHRA) have been associated with elevated metal ion levels, suggesting that excessive wear may occur due to edge-loading of these MoM implants. This study aimed to quantify in vivo edge-load...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.14.2000019
更新日期:2012-04-01 00:00:00
abstract:Objectives:The paradoxical migration of the femoral neck element (FNE) superomedially against gravity, with respect to the intramedullary component of the cephalomedullary device, is a poorly understood phenomenon increasingly seen in the management of pertrochanteric hip fractures with the intramedullary nail. The aim...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.87.BJR-2018-0271.R1
更新日期:2019-08-02 00:00:00
abstract:OBJECTIVES:Evidence -based medicine (EBM) is designed to inform clinical decision-making within all medical specialties, including orthopaedic surgery. We recently published a pilot survey of the Canadian Orthopaedic Association (COA) membership and demonstrated that the adoption of EBM principles is variable among Can...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.54.2000578
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVES:To investigate psychosocial and biomedical outcomes following total hip replacement (THR) and to identify predictors of recovery from THR. METHODS:Patients with osteoarthritis (OA) on the waiting list for primary THR in North West England were assessed pre-operatively and at six and 12 months post-operative...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.211.2000206
更新日期:2013-11-27 00:00:00
abstract:OBJECTIVES:Pedicle-lengthening osteotomy is a novel surgery for lumbar spinal stenosis (LSS), which achieves substantial enlargement of the spinal canal by expansion of the bilateral pedicle osteotomy sites. Few studies have evaluated the impact of this new surgery on spinal canal volume (SCV) and neural foramen dimens...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.56.2000469
更新日期:2016-06-01 00:00:00
abstract:Objectives:The primary stability of the cementless Oxford Unicompartmental Knee Replacement (OUKR) relies on interference fit (or press fit). Insufficient interference may cause implant loosening, whilst excessive interference could cause bone damage and fracture.The aim of this study was to identify the optimal interf...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.73.BJR-2017-0193.R1
更新日期:2018-05-05 00:00:00
abstract::Fractures of the proximal femur are one of the greatest challenges facing the medical community, constituting a heavy socioeconomic burden worldwide. Controversy exists regarding the optimal treatment for patients with unstable trochanteric proximal femoral fractures. The recognised treatment alternatives are extramed...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.210.2000183
更新日期:2013-10-02 00:00:00
abstract:OBJECTIVES:A patient-centred approach, usually achieved through shared decision making, has the potential to help improve decision making around knee arthroplasty surgery. However, such an approach requires an understanding of the factors involved in patient decision making. This review's objective is to systematically...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.410.2000420
更新日期:2015-10-01 00:00:00
abstract:Objectives:The aim of this study was to analyze drain fluid, blood, and urine simultaneously to follow the long-term release of vancomycin from a biphasic ceramic carrier in major hip surgery. Our hypothesis was that there would be high local vancomycin concentrations during the first week with safe low systemic trough...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.82.BJR-2018-0174.R2
更新日期:2019-03-02 00:00:00
abstract:Objectives:We studied subchondral intraosseous pressure (IOP) in an animal model during loading, and with vascular occlusion. We explored bone compartmentalization by saline injection. Materials and Methods:Needles were placed in the femoral condyle and proximal tibia of five anaesthetized rabbits and connected to pre...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.78.BJR-2017-0343.R2
更新日期:2018-09-15 00:00:00
abstract:AIMS:The study aimed to determine whether the microRNA miR21-5p (MiR21) mediates temporomandibular joint osteoarthritis (TMJ-OA) by targeting growth differentiation factor 5 (Gdf5). METHODS:TMJ-OA was induced in MiR21 knockout (KO) mice and wild-type (WT) mice by a unilateral anterior crossbite (UAC) procedure. Mouse ...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.910.BJR-2020-0140.R1
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVES:The radiographic union score for tibial (RUST) fractures was developed by Whelan et al to assess the healing of tibial fractures following intramedullary nailing. In the current study, the repeatability and reliability of the RUST score was evaluated in an independent centre (a) using the original descriptio...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.54.2000628
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVES:The goals of this study were: 1) to determine if high-fat diet (HFD) feeding in female mice would negatively impact biomechanical and histologic consequences on the Achilles tendon and quadriceps muscle; and 2) to investigate whether exercise and branched-chain amino acid (BCAA) supplementation would affect ...
journal_title:Bone & joint research
pub_type: 杂志文章
doi:10.1302/2046-3758.29.2000196
更新日期:2013-09-10 00:00:00