The effect of resveratrol on normal and osteoarthritic chondrocyte metabolism.

abstract：Objectives:Different criteria for assessing the reduction quality of trochanteric fractures have been reported. The Baumgaertner reduction quality criteria (BRQC) are relatively common and the Chang reduction quality criteria (CRQC) are relatively new. The objectives of the current study were to compare the reliability...

journal_title：Bone & joint research

authors： Mao W,Ni H,Li L,He Y,Chen X,Tang H,Dong Y

更新日期：2019-11-02 00:00:00

abstract：OBJECTIVES:To assess the accuracy of patient-specific instruments (PSIs) versus standard manual technique and the precision of computer-assisted planning and PSI-guided osteotomies in pelvic tumour resection. METHODS:CT scans were obtained from five female cadaveric pelvises. Five osteotomies were designed using Mimic...

journal_title：Bone & joint research

authors： Sallent A,Vicente M,Reverté MM,Lopez A,Rodríguez-Baeza A,Pérez-Domínguez M,Velez R

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVES:To study the measurement properties of a joint specific patient reported outcome measure, a measure of capability and a general health-related quality of life (HRQOL) tool in a large cohort of patients with a hip fracture. METHODS:Responsiveness and associations between the Oxford Hip Score (a hip specific ...

journal_title：Bone & joint research

authors： Parsons N,Griffin XL,Achten J,Costa ML

更新日期：2014-03-19 00:00:00

abstract：OBJECTIVES:As tumours of bone and soft tissue are rare, multicentre prospective collaboration is essential for meaningful research and evidence-based advances in patient care. The aim of this study was to identify barriers and facilitators encountered in large-scale collaborative research by orthopaedic oncological sur...

journal_title：Bone & joint research

authors： Rendon JS,Swinton M,Bernthal N,Boffano M,Damron T,Evaniew N,Ferguson P,Galli Serra M,Hettwer W,McKay P,Miller B,Nystrom L,Parizzia W,Schneider P,Spiguel A,Vélez R,Weiss K,Zumárraga JP,Ghert M

更新日期：2017-05-01 00:00:00

abstract：:In vivo animal experimentation has been one of the cornerstones of biological and biomedical research, particularly in the field of clinical medicine and pharmaceuticals. The conventional in vivo model system is invariably associated with high production costs and strict ethical considerations. These limitations led t...

journal_title：Bone & joint research

authors： Abubakar AA,Noordin MM,Azmi TI,Kaka U,Loqman MY

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:In order to ensure safety of the cell-based therapy for bone regeneration, we examined in vivo biodistribution of locally or systemically transplanted osteoblast-like cells generated from bone marrow (BM) derived mononuclear cells. METHODS:BM cells obtained from a total of 13 Sprague-Dawley (SD) green fluor...

journal_title：Bone & joint research

authors： Okabe YT,Kondo T,Mishima K,Hayase Y,Kato K,Mizuno M,Ishiguro N,Kitoh H

更新日期：2014-03-20 00:00:00

abstract：OBJECTIVES:The goals of this study were: 1) to determine if high-fat diet (HFD) feeding in female mice would negatively impact biomechanical and histologic consequences on the Achilles tendon and quadriceps muscle; and 2) to investigate whether exercise and branched-chain amino acid (BCAA) supplementation would affect ...

journal_title：Bone & joint research

authors： Boivin GP,Platt KM,Corbett J,Reeves J,Hardy AL,Elenes EY,Charnigo RJ,Hunter SA,Pearson KJ

更新日期：2013-09-10 00:00:00

abstract：OBJECTIVES:The number of surgical procedures performed each year to treat femoroacetabular impingement (FAI) continues to rise. Although there is evidence that surgery can improve symptoms in the short-term, there is no evidence that it slows the development of osteoarthritis (OA). We performed a feasibility study to d...

journal_title：Bone & joint research

authors： Palmer AJ,Thomas GE,Pollard TC,Rombach I,Taylor A,Arden N,Beard DJ,Andrade AJ,Carr AJ,Glyn-Jones S

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVES:We aimed to determine the effect of surgical approach on the histology of the femoral head following resurfacing of the hip. METHODS:We performed a histological assessment of the bone under the femoral component taken from retrieval specimens of patients having revision surgery following resurfacing of the ...

journal_title：Bone & joint research

authors： Amarasekera HW,Campbell PC,Parsons N,Achten J,Masters J,Griffin DR,Costa ML

更新日期：2013-09-18 00:00:00

abstract：:Bone is one of the most highly adaptive tissues in the body, possessing the capability to alter its morphology and function in response to stimuli in its surrounding environment. The ability of bone to sense and convert external mechanical stimuli into a biochemical response, which ultimately alters the phenotype and ...

journal_title：Bone & joint research

authors： Stewart S,Darwood A,Masouros S,Higgins C,Ramasamy A

更新日期：2020-05-16 00:00:00

abstract：Objectives:Recently, the field of tissue engineering has made numerous advances towards achieving artificial tendon substitutes with excellent mechanical and histological properties, and has had some promising experimental results. The purpose of this systematic review is to assess the efficacy of tissue engineering in...

journal_title：Bone & joint research

authors： González-Quevedo D,Martínez-Medina I,Campos A,Campos F,Carriel V

更新日期：2018-05-05 00:00:00

abstract：OBJECTIVES:Osteophytes are products of active endochondral and intramembranous ossification, and therefore could theoretically provide significant efficacy as bone grafts. In this study, we compared the bone mineralisation effectiveness of osteophytes and cancellous bone, including their effects on secretion of growth ...

journal_title：Bone & joint research

authors： Ishihara K,Okazaki K,Akiyama T,Akasaki Y,Nakashima Y

更新日期：2017-02-01 00:00:00

abstract：Objectives:The paradoxical migration of the femoral neck element (FNE) superomedially against gravity, with respect to the intramedullary component of the cephalomedullary device, is a poorly understood phenomenon increasingly seen in the management of pertrochanteric hip fractures with the intramedullary nail. The aim...

journal_title：Bone & joint research

authors： Law GW,Wong YR,Yew AK,Choh ACT,Koh JSB,Howe TS

更新日期：2019-08-02 00:00:00

abstract：:Chondrocyte hypertrophy represents a crucial turning point during endochondral bone development. This process is tightly regulated by various factors, constituting a regulatory network that maintains normal bone development. Histone deacetylase 4 (HDAC4) is the most well-characterized member of the HDAC class IIa fami...

journal_title：Bone & joint research

authors： Chen Z,Zhang Z,Guo L,Wei X,Zhang Y,Wang X,Wei L

更新日期：2020-05-16 00:00:00

abstract：Objectives:The aim of this study was to investigate the biomechanical effect of the anterolateral ligament (ALL), anterior cruciate ligament (ACL), or both ALL and ACL on kinematics under dynamic loading conditions using dynamic simulation subject-specific knee models. Methods:Five subject-specific musculoskeletal mod...

journal_title：Bone & joint research

authors： Kang KT,Koh YG,Park KM,Choi CH,Jung M,Shin J,Kim SH

更新日期：2019-12-03 00:00:00

abstract：OBJECTIVES:To investigate the differences of open reduction and internal fixation (ORIF) of complex AO Type C distal radius fractures between two different models of a single implant type. METHODS:A total of 136 patients who received either a 2.4 mm (n = 61) or 3.5 mm (n = 75) distal radius locking compression plate (...

journal_title：Bone & joint research

authors： von Recum J,Matschke S,Jupiter JB,Ring D,Souer JS,Huber M,Audigé L

更新日期：2012-06-01 00:00:00

abstract：Aims:Induction heating is a noninvasive, nonantibiotic treatment modality that can potentially be used to cause thermal damage to the bacterial biofilm on the metal implant surface. The purpose of this study was to determine the effectiveness of induction heating on killing Staphylococcus epidermidis from biofilm and t...

journal_title：Bone & joint research

authors： Pijls BG,Sanders IMJG,Kujiper EJ,Nelissen RGHH

更新日期：2020-05-16 00:00:00

abstract：OBJECTIVES:Pseudotumours (abnormal peri-prosthetic soft-tissue reactions) following metal-on-metal hip resurfacing arthroplasty (MoMHRA) have been associated with elevated metal ion levels, suggesting that excessive wear may occur due to edge-loading of these MoM implants. This study aimed to quantify in vivo edge-load...

journal_title：Bone & joint research

authors： Kwon YM,Mellon SJ,Monk P,Murray DW,Gill HS

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVES:Local corticosteroid infiltration is a common practice of treatment for lateral epicondylitis. In recent studies no statistically significant or clinically relevant results in favour of corticosteroid injections were found. The injection of autologous blood has been reported to be effective for both intermed...

journal_title：Bone & joint research

authors： Dojode CM

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVES:Microindentation has the potential to measure the stiffness of an individual patient's bone. Bone stiffness plays a crucial role in the press-fit stability of orthopaedic implants. Arming surgeons with accurate bone stiffness information may reduce surgical complications including periprosthetic fractures. T...

journal_title：Bone & joint research

authors： Arnold M,Zhao S,Ma S,Giuliani F,Hansen U,Cobb JP,Abel RL,Boughton O

更新日期：2017-09-01 00:00:00

abstract：Aims:Commonly performed unicompartmental knee arthroplasty (UKA) is not designed for the lateral compartment. Additionally, the anatomical medial and lateral tibial plateaus have asymmetrical geometries, with a slightly dished medial plateau and a convex lateral plateau. Therefore, this study aims to investigate the na...

journal_title：Bone & joint research

authors： Koh YG,Lee JA,Lee HY,Kim HJ,Chung HS,Kang KT

更新日期：2020-01-08 00:00:00

abstract：:Fractures of the proximal femur are one of the greatest challenges facing the medical community, constituting a heavy socioeconomic burden worldwide. Controversy exists regarding the optimal treatment for patients with unstable trochanteric proximal femoral fractures. The recognised treatment alternatives are extramed...

journal_title：Bone & joint research

authors： Griffin XL,McArthur J,Achten J,Parsons N,Costa ML

更新日期：2013-10-02 00:00:00

abstract：OBJECTIVES:Pedicle-lengthening osteotomy is a novel surgery for lumbar spinal stenosis (LSS), which achieves substantial enlargement of the spinal canal by expansion of the bilateral pedicle osteotomy sites. Few studies have evaluated the impact of this new surgery on spinal canal volume (SCV) and neural foramen dimens...

journal_title：Bone & joint research

authors： Li P,Qian L,Wu WD,Wu CF,Ouyang J

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVES:Small animal models of fracture repair primarily investigate indirect fracture healing via external callus formation. We present the first described rat model of direct fracture healing. METHODS:A rat tibial osteotomy was created and fixed with compression plating similar to that used in patients. The proce...

journal_title：Bone & joint research

authors： Savaridas T,Wallace RJ,Muir AY,Salter DM,Simpson AH

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to explore dimensionality of the Oxford Hip Score (OHS) and examine whether self-reported pain and functioning can be distinguished in the form of subscales. METHODS:This was a secondary data analysis of the UK NHS hospital episode statistics/patient-reported outcome measures ...

journal_title：Bone & joint research

authors： Harris KK,Price AJ,Beard DJ,Fitzpatrick R,Jenkinson C,Dawson J

更新日期：2014-11-01 00:00:00

abstract：:The treatment of osteochondral lesions and osteoarthritis remains an ongoing clinical challenge in orthopaedics. This review examines the current research in the fields of cartilage regeneration, osteochondral defect treatment, and biological joint resurfacing, and reports on the results of clinical and pre-clinical s...

journal_title：Bone & joint research

authors： Myers KR,Sgaglione NA,Grande DA

更新日期：2013-09-16 00:00:00

abstract：Objectives:The aim of this study was to analyze drain fluid, blood, and urine simultaneously to follow the long-term release of vancomycin from a biphasic ceramic carrier in major hip surgery. Our hypothesis was that there would be high local vancomycin concentrations during the first week with safe low systemic trough...

journal_title：Bone & joint research

authors： Stravinskas M,Nilsson M,Vitkauskiene A,Tarasevicius S,Lidgren L

更新日期：2019-03-02 00:00:00

abstract：:Cartilage repair in terms of replacement, or regeneration of damaged or diseased articular cartilage with functional tissue, is the 'holy grail' of joint surgery. A wide spectrum of strategies for cartilage repair currently exists and several of these techniques have been reported to be associated with successful clin...

journal_title：Bone & joint research

authors： Cook JL,Hung CT,Kuroki K,Stoker AM,Cook CR,Pfeiffer FM,Sherman SL,Stannard JP

更新日期：2014-04-02 00:00:00

abstract：AIMS:This study aimed to investigate the effect of solute carrier family 20 member 2 (SLC20A2) gene mutation (identified from a hereditary multiple exostoses family) on chondrocyte proliferation and differentiation. METHODS:ATDC5 chondrocytes were cultured in insulin-transferrin-selenium medium to induce differentiati...

journal_title：Bone & joint research

authors： Li Y,Lin X,Zhu M,Xun F,Li J,Yuan Z,Liu Y,Xu H

更新日期：2020-11-01 00:00:00

abstract：Objectives:We studied subchondral intraosseous pressure (IOP) in an animal model during loading, and with vascular occlusion. We explored bone compartmentalization by saline injection. Materials and Methods:Needles were placed in the femoral condyle and proximal tibia of five anaesthetized rabbits and connected to pre...

journal_title：Bone & joint research

authors： Beverly M,Mellon S,Kennedy JA,Murray DW

更新日期：2018-09-15 00:00:00