Causes of adult splanchnic vein thrombosis in the mediterranean area.

abstract：:Sickle cell disease (SCD) is an extremely heterogeneous disease that has been associated with global morbidity and early mortality. More effective and inexpensive therapies are needed. During the last five years, the landscape of the pharmacotherapy of SCD has changed dramatically. Currently, 54 drugs have been used o...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Ballas SK

更新日期：2020-01-01 00:00:00

abstract：:JAK2V617F is a gain of function point mutation that occurs in Myeloproliferative Neoplasm (MPN) patients and deranges their hemopoiesis at cellular level. We speculate that hyperfunctioning JAK2 can modify osteoclast (OCL) homeostasis in MPN patients. We studied 18 newly diagnosed MPN patients and four age-matched nor...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Spanoudakis E,Papoutselis M,Bazdiara I,Lamprianidi E,Kordella X,Tilkeridis C,Tsatalas C,Kotsianidis I

更新日期：2018-11-01 00:00:00

abstract：:The introduction of newer cytotoxic monoclonal antibodies and chimeric antigen receptor modified T cells is opening a new age in the management of B-lineage adult acute lymphoblastic leukemia. This therapeutic change must be very positively acknowledged because of the limits of intensive chemotherapy programs and allo...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Maino E,Scattolin AM,Viero P,Sancetta R,Pascarella A,Vespignani M,Bassan R

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Multiple myeloma (MM) is a haematological malignancy associated with kidney injury resulting from cast nephropathy, which can be caused by monoclonal free light chains (FLC). It has been demonstrated that early reduction of FLC can lead to a higher proportion of patients recovering renal function with a bett...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Khalafallah AA,Loi SW,Love S,Mohamed M,Mace R,Khalil R,Girgs M,Raj R,Mathew M

更新日期：2013-01-01 00:00:00

abstract：Background:Alpha Thalassemia (α-thal) is a heterogeneous group of hereditary alterations caused by deletions that affect alpha regulatory genes, and the 3.7Kb deletion is the most frequent worldwide. The prevalence ranges from 20% and 35% in Brazil, depending mainly on race, predominant in Afro-descendants. Purpose:Th...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Anselmo FC,Soumanou AG,de Aguiar Ferreira C,Sobrinha FMV,Castro ACS,Brito RO,da Mota AJ,de Souza Gonçalves M,de Moura Neto JP

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Better survival of thalassemia patients allowed previously unrecognized renal complications to emerge. OBJECTIVES:Assess prevalence and early predictors of renal dysfunction in young β-thalassemia major (β-TM) and intermedia (β-TI) patients. SUBJECTS:66 β-TM (group I), 26 β-TI (group II) Egyptian patients ...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Tantawy AA,El Bablawy N,Adly AA,Ebeid FS

更新日期：2014-09-01 00:00:00

abstract：:The clinical picture of patients with sickle cell anemia (SCA) is associated with several complications some of which could be fatal. The objective of this study is to analyze the causes of death and the effect of sex and age on survival of Brazilian patients with SCA. Data of patients with SCA who were seen and follo...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： do Nascimento EM,de Castro Lobo CL,de Bragança Pereira B,Ballas SK

更新日期：2019-03-01 00:00:00

abstract：:The recent focus on the potential link between periodontal and cardiovascular disease (PD and CVD) is part of the larger renewed interest on the role of infection and inflammation in the etiology of atherosclerosis and its clinical manifestations. Periodontal Disease is an inflammatory process affecting the periodonti...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Trevisan M,Dorn J

更新日期：2010-10-01 00:00:00

abstract：INTRODUCTION:Bone marrow aspiration and biopsy still remains as one of the vital tests for confirmation of diagnosis of visceral Leishmaniasis. The aim of the present study is to assess the relative frequency of common, uncommon and atypical hematological findings in cases of Visceral Leishmaniasis. MATERIALS #ENTITYS...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Bhatia P,Haldar D,Varma N,Marwaha R,Varma S

更新日期：2011-01-01 00:00:00

abstract：:Sitagliptin, a modern antidiabetic agent which is weight neutral and associated with low rate of hypoglycaemias, is being increasingly used in type 2 diabetes mellitus (DM). However, there is a paucity of data about its efficacy and safety in beta-thalassaemia major (β-TM). This retrospective case series of five patie...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Zonoozi S,Barnard M,Prescott E,Jones R,Shah FT,Tzoulis P

更新日期：2017-01-01 00:00:00

abstract：:The large multimeric glycoprotein Von Willebrand factor (VWF) is best known for its role in haemostasis; however in recent years other functions of VWF have been identified, indicating that this protein is involved in multiple vascular processes. We recently described a new role for VWF in controlling angiogenesis, wh...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Randi AM,Laffan MA,Starke RD

更新日期：2013-09-02 00:00:00

abstract：INTRODUCTION:Follicular lymphoma (FL) is an indolent lymphoproliferative disorder of B-cells with variable clinical behavior. It is the second most common subtype of Non-Hodgkin lymphoma in western countries but reported to have a lower incidence in Asia. MATERIALS AND METHODS:Cases of FL diagnosed in the Department o...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Sylvia MT,Dey B,Basu D,Jacob SE,Kar R,Dubashi B

更新日期：2016-11-01 00:00:00

abstract：:POEMS syndrome is a rare, chronic and disabling condition. The causes of this condition remain unknown; however, chronic overproduction of proinflammatory cytokines appears to be a major contributor. Early diagnosis is essential to start treatment before the clinical state of the patient becomes compromised. A complet...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Nozza A

更新日期：2017-09-01 00:00:00

abstract：:In Primary Myelofibrosis (PMF), megakaryocyte dysplasia/hyperplasia determines the release of inflammatory cytokines that, in turn, stimulate stromal cells and induce bone marrow fibrosis. The pathogenic mechanism and the cells responsible for progression to bone marrow fibrosis in PMF are not completely understood. T...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Malara A,Abbonante V,Zingariello M,Migliaccio A,Balduini A

更新日期：2018-11-01 00:00:00

abstract：INTRODUCTION:Sickle cell disease (SCD) is one of the leading causes of morbidity and mortality worldwide, causing damage and dysfunction in multiple organs. The complications of this disease are numerous, affect every organ and/or tissue in the body and vary considerably among patients over the time challenging its man...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Yassin M,Soliman A,De Sanctis V,Nashwan A,Abusamaan S,Moustafa A,Kohla S,Soliman D

更新日期：2017-06-20 00:00:00

abstract：Background:Foetal haemoglobin (HbF) is a major modifying factor influencing sickle cell disease (SCD) severity. Despite this, HbF estimation is not routinely done in Nigeria. The relationship between HbF and SCD severity among affected children is also poorly studied. Methods:In this descriptive cross-sectional study,...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Adeodu OO,Akinlosotu MA,Adegoke SA,Oseni SBA

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Homozygous or double heterozygous factor XIII (FXIII) deficiency is characterized by soft tissue hematomas, intracranial and delayed spontaneous bleeding. Alterations of thromboelastography (TEG) parameters in these patients have been reported. The aim of the study was to show results of TEG, TEG Lysis (Lys ...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Martinuzzo M,Barrera L,Altuna D,Baña FT,Bieti J,Amigo Q,D'Adamo M,López MS,Oyhamburu J,Otaso JC

更新日期：2016-08-16 00:00:00

abstract：INTRODUCTION:Bortezomib is a proteasome inhibitor that targets myeloma cell and its bone marrow microenvironment. Intravenous Bortezomib with or without dexamethasone, is effective and well tolerated in patients with relapsed/refractory multiple myeloma (MM). METHODS:We used Bortezomib without corticosteroids, to avoi...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Gentilini F,Levi A,Federico V,Russo E,Foà R,Petrucci MT

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:Low-dose cytarabine (LD-AraC) is still regarded as the standard of care in elderly patients with acute myeloid leukemia (AML) 'unfit' for intensive chemotherapy. In this study, we reported our experience with LD-AraC in patients ≥ 70 years old and compared the results to those of intensive chemotherapy, best...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Heiblig M,Elhamri M,Tigaud I,Plesa A,Barraco F,Labussière H,Ducastelle S,Michallet M,Nicolini F,Plesa C,Wattel E,Salles G,Thomas X

更新日期：2016-01-01 00:00:00

abstract：:Kikuchi-Fujimoto Disease (KFD), also known as histiocytic necrotizing lymphadenitis [corrected], is a benign, self-limiting disease that manifests primarily as cervical lymphadenopathy but may include low-grade fever, headache, and fatigue. There is a higher incidence of KFD in women aged 20-35 years and in Asian popu...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Deaver D,Naghashpour M,Sokol L

更新日期：2014-01-01 00:00:00

abstract：:Allogeneic hematopoietic cell transplantation (HCT) is the only curative treatment for patients with myelodysplastic syndromes (MDS). Most patients with MDS are older than 60 years and age-associated morbidities limit the patients' options for curative transplant therapy. Since the development of conditioning regimens...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Field T,Anasetti C

更新日期：2010-08-05 00:00:00

abstract：:Peripheral neuropathies are a vast group of diseases with heterogeneous aetiologies, including genetic and acquired causes. Several haematological disorders may cause an impairment of the peripheral nervous system, with diverse mechanisms and variable clinical, electrophysiological and pathological manifestations. In ...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Sabatelli M,Laurenti L,Luigetti M

更新日期：2018-09-01 00:00:00

abstract：:We describe the entire process leading to the start-up of a hematopoietic stem cell transplantation center at the Hiwa Cancer Hospital, in the city of Sulaymaniyah, Kurdistan Iraqi Region. This capacity building project was funded by the Italian Development Cooperation Agency and implemented with the support of the vo...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Majolino I,Othman D,Rovelli A,Hassan D,Rasool L,Vacca M,Abdalrahman N,Abdullah C,Ahmed Z,Ali D,Ali K,Broggi C,Calabretta C,Canesi M,Ciabatti G,Del Fante C,De Sapio E,Dore G,Frigato A,Gabriel M,Ipsevich F,Kareem

更新日期：2017-04-15 00:00:00

abstract：:Acinetobacter baumannii is an important opportunistic pathogen, responsible for approximately 10% of all gram-negative nosocomial infection. The aim of this study was to determine aminoglycoside and quinolone resistance genes and their antimicrobial susceptibility profile in the clinically A. baumannii. In this cross-...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Mirnejad R,Heidary M,Bahramian A,Goudarzi M,Pournajaf A

更新日期：2018-07-01 00:00:00

abstract：:In the last 15 years, highly active antiretroviral therapy (HAART) has determined a dramatic reduction of both morbidity and mortality in human immunodeficiency virus (HIV)-infected subjects, transforming this infection in a chronic and manageable disease. Patients surviving with HIV in the developed world, in larger ...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： de Gaetano Donati K,Cauda R,Iacoviello L

更新日期：2010-01-01 00:00:00

abstract：:Nebulized colistin (NC) is used for the treatment of pneumonia due to multidrug- resistant Gram-negative bacteria. In this one-year case-control study, our objective was to evaluate the effect of NC on the ventilator circuit (VC) components. The case group consisted of 25 mechanically-ventilated patients who received ...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Ghonimat IM,Nazer LH,Aqel F,Mohammad MK,Hawari FI,Le J

更新日期：2015-04-20 00:00:00

abstract：:Echinococcosis is an endemic zoonosis in the Mediterranean area, with Albania interested actually to a level that is becoming a public health concern. Authors describe preliminary data from the only tertiary (university) medical facility of Albania, positioned in the capital of the country (Tirana), with 333 new cases...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Pilaca A,Vyshka G,Pepa A,Shytaj K,Shtjefni V,Boçari A,Beqiri A,Kraja D

更新日期：2014-02-16 00:00:00

abstract：:We describe the case of a 17- year old female who developed fatal haemophagocytic syndrome (HPS) one month following acute infection caused by Epstein-Barr virus (EBV). Despite initiation of treatment and reduction of EBV load, laboratory signs of HPS as severe cytopenia, hypofibrinogenemia, hyperferritinemia and hype...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Torti L,Larocca LM,Massini G,Cuccaro A,Maiolo E,Santangelo R,Bianchi M,Pennisi MA,Hohaus S,Teofili L

更新日期：2012-01-01 00:00:00

abstract：:Long-term survival of relapsed/refractory acute myeloid leukemia (AML) remains a major problem, particularly in patients not eligible for transplantation.We hereby evaluated the feasibility and efficacy of adding Gemtuzumab Ozogamicin to salvage chemotherapy (Ara-C, Idarubicine, Peg-Filgrastim) in relapsed/refractory ...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Capria S,Trisolini SM,Minotti C,Stefanizzi C,Cardarelli L,Cartoni C,Diverio D,De Propris MS,Mancini M,Micozzi A,Foà R,Meloni G

更新日期：2012-01-01 00:00:00

abstract：:The clinical manifestations of severe malaria are several and occur in different anatomical sites. Both parasite- and host-related factors contribute to the pathogenicity of the severe forms of the disease. Cytoadherence of infected red blood cells to the vascular endothelium of different organs and rosetting are uniq...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Autino B,Corbett Y,Castelli F,Taramelli D

更新日期：2012-01-01 00:00:00