Combined hepatocellular and cholangiocellular carcinoma in a non-cirrhotic liver.

abstract：:Prevention of human diseases has become a major focus of biomedical investigators around the world. Our current screening and treatment regimens for colorectal cancer are not effective, as indicated by the fact that this disease is the second leading cause of death from cancer in the United States. Recently published ...

journal_title：Journal of gastroenterology

authors： DuBois RN,Smalley WE

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Vaniprevir is a potent macrocyclic hepatitis C virus (HCV) nonstructural protein 3/4A protease inhibitor. This phase III study evaluated the safety and efficacy of vaniprevir in combination with peginterferon alfa-2b and ribavirin (PR) for 24 weeks compared with PR alone for 48 weeks in treatment-naive Japan...

journal_title：Journal of gastroenterology

authors： Hayashi N,Nakamuta M,Takehara T,Kumada H,Takase A,Howe AY,Ludmerer SW,Mobashery N

更新日期：2016-04-01 00:00:00

abstract：:Primary sclerosing cholangitis is very rare in Japan. The aim of the present study was to identify the characteristics of such patients in Japan. A questionnaire was sent to the members of the Japanese Society of Gastroenterology and responses for 192 cases were analyzed. There was male predominancy (61%), and two pea...

journal_title：Journal of gastroenterology

authors： Takikawa H,Manabe T

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Bleeding of the lower gastrointestinal tract requires hospitalization and can cause in-hospital death in the most serious cases; however, only a few studies have evaluated in-hospital death from bleeding of the lower gastrointestinal tract. The aim of this study was to investigate the in-hospital mortality o...

journal_title：Journal of gastroenterology

authors： Niikura R,Yasunaga H,Yamaji Y,Horiguchi H,Fushimi K,Yamada A,Hirata Y,Koike K

更新日期：2015-05-01 00:00:00

abstract：:Patients with longstanding extensive colitis, both ulcerative colitis and Crohn's colitis, have an increased risk of developing colorectal cancer. Because of this risk, colonoscopic surveillance for neoplasia is recommended by most authorities. Although there has been no randomised controlled trial to demonstrate surv...

journal_title：Journal of gastroenterology

authors： Rutter MD

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Recently, the novel gene DOG1 has been found to be overexpressed in most gastrointestinal stromal tumors (GISTs) specifically within the field of soft tissue tumors. DOG1 might play a role in development of GISTs and have potential as a diagnostic marker and therapeutic target, but the biological function an...

journal_title：Journal of gastroenterology

authors： Miwa S,Nakajima T,Murai Y,Takano Y,Sugiyama T

更新日期：2008-01-01 00:00:00

abstract：:We report a case of primary biliary cirrhosis (PBC)-autoimmune hepatitis (AIH) overlap syndrome with concurrent idiopathic thrombocytopenic purpura (ITP) and Hashimoto's disease with positivity for anticentromere antibody. The patient was a 64-year-old woman with symptoms of jaundice and general fatigue. About 30 year...

journal_title：Journal of gastroenterology

authors： Arakawa Y,Amaki S,Miyakawa H,Sakai T,Gotou I,Tanaka N,Moriyama M,Iwasaki A,Sugitani M,Arakawa Y

更新日期：2004-01-01 00:00:00

abstract：:From its pattern of metastasis and recurrence, gastric carcinoma can be recognized as a slow-growing malignancy whose local control is still the most important part of treatment. With application of asymptomatic population screening and awareness of the high risk of this disease among the general population in Japan, ...

journal_title：Journal of gastroenterology

authors： Sasako M

更新日期：2000-01-01 00:00:00

abstract：:This study was designed to clarify what differences the last 25 years have made in surgical results for patients with hepatocellular carcinoma (HCC). We examined results for 716 hepatectomized patients in four treatment eras: first era (1973-1980; n = 58), second era (1981-1985; n = 155), third era (1986-1990; n = 243...

journal_title：Journal of gastroenterology

authors： Yamanaka N,Takata M,Tanaka T,Yamanaka J,Yasui C,Ando T,Kuroda N,Maeda S,Okamoto E

更新日期：2000-01-01 00:00:00

abstract：:Endoscopic surveillance of Barrett's esophagus has become a foundation of the management of esophageal adenocarcinoma (EAC). Surveillance for Barrett's esophagus commonly involves periodic upper endoscopy with biopsies of suspicious areas and random four-quadrant biopsies. However, targeted biopsies using narrow-band ...

journal_title：Journal of gastroenterology

authors： Ishihara R,Goda K,Oyama T

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:For patients with chronic hepatitis due to hepatitis B virus (HBV), factors predicting hepatocellular carcinoma (HCC) other than high levels of HBV-DNA and alanine aminotransferase (ALT) are needed to prevent HCC development, as many patients with chronic HBV infection fulfill these conditions. The purpose o...

journal_title：Journal of gastroenterology

authors： Shoji B,Ikeda F,Fujioka S,Kobashi H,Yasunaka T,Miyake Y,Shiraha H,Takaki A,Nouso K,Iwasaki Y,Yamamoto K

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Although pancreatic duct guidewire placement (P-GW) for achieving selective biliary cannulation is reported to be effective in patients in whom endoscopic retrograde cholangiopancreatography (ERCP) is difficult, this technique entails a possible increased risk of post-ERCP pancreatitis. We conducted a prospe...

journal_title：Journal of gastroenterology

authors： Ito K,Fujita N,Noda Y,Kobayashi G,Obana T,Horaguchi J,Takasawa O,Koshita S,Kanno Y,Ogawa T

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:We recently reported that the presence of a papillary adenocarcinoma (pap) component was an independent risk factor for lymphatic involvement in endoscopically resected early gastric cancer (EGC). This study aimed to investigate the potential association between the presence of a pap component in EGC and lym...

journal_title：Journal of gastroenterology

authors： Sekiguchi M,Kushima R,Oda I,Suzuki H,Taniguchi H,Sekine S,Fukagawa T,Katai H

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:We recently reported the real-world changes in the etiologies of liver cirrhosis (LC) based on nationwide survey data and assessed the etiologies of LC with hepatocellular carcinoma (HCC). METHODS:Fifty-five participants from 68 institutions provided data on 23,637 patients with HCC-complicated LC. The chan...

journal_title：Journal of gastroenterology

authors： Enomoto H,Ueno Y,Hiasa Y,Nishikawa H,Hige S,Takikawa Y,Taniai M,Ishikawa T,Yasui K,Takaki A,Takaguchi K,Ido A,Kurosaki M,Kanto T,Nishiguchi S,Japan Etiology of Liver Cirrhosis Study Group in the 54th Annual Meeting of JSH.

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND:Few studies have investigated measures to prevent small bowel injuries induced by aspirin. Our aim was to evaluate the effect of probiotic treatment on the small bowel injuries induced by chronic low-dose aspirin use. METHODS:Thirty-five patients who took low-dose enteric-coated aspirin 100 mg daily (for mo...

journal_title：Journal of gastroenterology

authors： Endo H,Higurashi T,Hosono K,Sakai E,Sekino Y,Iida H,Sakamoto Y,Koide T,Takahashi H,Yoneda M,Tokoro C,Inamori M,Abe Y,Nakajima A

更新日期：2011-07-01 00:00:00

abstract：:Interleukin 6 (IL-6) is a pleiotropic cytokine produced by a wide variety of lymphoid and non-lymphoid tissues. We studied the relationship between IL-6 and the liver in an attempt to elucidate this cytokine's role in hepatitis C-induced liver inflammation. We investigated the behavior of serum IL-6 in 25 patients wit...

journal_title：Journal of gastroenterology

authors： Malaguarnera M,Di Fazio I,Romeo MA,Restuccia S,Laurino A,Trovato BA

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Inflammatory bowel disease (IBD) and resultant colitis occurring prior to puberty are frequently associated with delayed puberty and losses of growth and bone mineralization. Some of this delay may be due to colonic inflammation and associated systemic inflammation. To date no treatments for IBD have been sh...

journal_title：Journal of gastroenterology

authors： Deboer MD,Steinman J,Li Y

更新日期：2012-06-01 00:00:00

abstract：:Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis is the most frequent complication of ERCP. Several meta-analyses have examined the effects of protease inhibitors (gabexate mesilate, ulinastatin, and nafamostat mesilate) and non-steroidal anti-inflammatory drugs (NSAIDs) on post-ERCP pancreatiti...

journal_title：Journal of gastroenterology

authors： Yuhara H,Ogawa M,Kawaguchi Y,Igarashi M,Shimosegawa T,Mine T

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:The clinicopathologic features of cystic neoplasms of the liver, such as cystadenoma and cystadenocarcinoma, are poorly defined because these lesions are extremely rare. METHODS:Clinicopathologic findings in six patients who underwent surgery for a cystic hepatic neoplasm were reviewed retrospectively to de...

journal_title：Journal of gastroenterology

authors： Hai S,Hirohashi K,Uenishi T,Yamamoto T,Shuto T,Tanaka H,Kubo S,Tanaka S,Kinoshita H

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Recently, a significant relationship between gastric cancer and Helicobacter pylori infection has been proven. The purpose of this study was to elucidate the actual conditions of H. pylori infection in Japanese teenagers. METHODS:The study subjects were students at a certain high school between 2007 and 200...

journal_title：Journal of gastroenterology

authors： Akamatsu T,Ichikawa S,Okudaira S,Yokosawa S,Iwaya Y,Suga T,Ota H,Tanaka E

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Although colorectal cancer (CRC) is one of the most common causes of cancer mortality, early-stage detection improves survival rates dramatically. Because cancer impacts important metabolic pathways, the alteration of metabolite levels as a potential biomarker of early-stage cancer has been the focus of many...

journal_title：Journal of gastroenterology

authors： Uchiyama K,Yagi N,Mizushima K,Higashimura Y,Hirai Y,Okayama T,Yoshida N,Katada K,Kamada K,Handa O,Ishikawa T,Takagi T,Konishi H,Kuriu Y,Nakanishi M,Otsuji E,Itoh Y,Naito Y

更新日期：2017-06-01 00:00:00

abstract：:Three-dimensional-computed tomography (3D-CT) cholangiography is a 3D shaded surface display image of the biliary tract obtained by using helical CT after intravenous cholangiography or cholangiography per percutaneous transhepatic cholangio-drainage tube. We investigated whether 3D-CT cholangiography could provide a ...

journal_title：Journal of gastroenterology

authors： Kinami S,Yao T,Kurachi M,Ishizaki Y

更新日期：1999-02-01 00:00:00

abstract：:We report a case of living-related partial liver transplantation for decompensated hepatitis B without reactivation of hepatitis B in the following 30 months, and we analyze the factors that indicate a favorable prognosis for transplantation. The 42-year-old female patient received continuously administered lamivudine...

journal_title：Journal of gastroenterology

authors： Hasegawa K,Hashimoto E,Kanai N,Ogawa M,Naritomi T,Taniai M,Takasaki K,Hayashi N

更新日期：2001-09-01 00:00:00

abstract：:An association of hidradenitis suppurativa with Crohn's disease is supported by previous repent. We here report a patient with hidradenitis suppurativa who subsequently developed peripheral arthritis, sacroiliitis, and Crohn's disease. A significant attenuation of bowel, cutaneous, and joint symptoms was achieved afte...

journal_title：Journal of gastroenterology

authors： Roussomoustakaki M,Dimoulios P,Chatzicostas C,Kritikos HD,Romanos J,Panayiotides JG,Kouroumalis EA

更新日期：2003-01-01 00:00:00

abstract：:We present herein a case of a 75-year-old Japanese man who had developed a pancreatic abscess 7 years after a longitudinal pancreatojejunostomy for chronic pancreatitis. The patient, a heavy drinker of alcohol, underwent surgical decompression of a ductal obstruction to relieve persistent abdominal pain due to severel...

journal_title：Journal of gastroenterology

authors： Suzuki A,Matsunaga T,Aoki S,Hirayama T,Nakagawa N,Shibata K,Yabana T,Kawasaki H,Takasaka H,Sasaki K,Katsuramaki T,Mukaiya M,Hirata K,Imai K

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Insufflation with carbon dioxide (CO(2)) in colonoscopy has not been widely adopted and, consequently, limited data are available on insufflated gas volume and blood pCO(2). The aim of this study was to compare CO(2) and air as an insufflation agent in patients undergoing colonoscopy without sedation in term...

journal_title：Journal of gastroenterology

authors： Yamano HO,Yoshikawa K,Kimura T,Yamamoto E,Harada E,Kudou T,Katou R,Hayashi Y,Satou K

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Mucosal breaks induced by gastroesophageal reflux of gastric contents were more frequently found on the right anterior wall of the lower esophagus. Bleeding from esophageal varices may be also derived from gastroesophageal reflux. The circumferential location of the ruptured esophageal varices was evaluated ...

journal_title：Journal of gastroenterology

authors： Okamoto E,Amano Y,Fukuhara H,Furuta K,Miyake T,Sato S,Ishihara S,Kinoshita Y

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinases (MMPs) are one of the major classes of proteolytic enzymes involved in tumor invasion and metastasis, being inhibited by naturally occurring tissue inhibitors of metalloproteinases (TIMPs). In this study, we examined the expression of MMP-2, MMP-9, membrane-type 1 (MT1)-MMP, TIMP-1,...

journal_title：Journal of gastroenterology

authors： Shim KN,Jung SA,Joo YH,Yoo K

更新日期：2007-02-01 00:00:00

abstract：:We investigated the adverse effects of sulfasalazine in the treatment of inflammatory bowel disease in Japan. In our first survey, adverse effects were observed in 52 out of 751 patients with ulcerative colitis (6.9%) and in 8 out of 221 patients with Crohn's disease (3.6%); i.e., such effects were observed in 60 out ...

journal_title：Journal of gastroenterology

authors： Nakajima H,Munakata A,Yoshida Y

更新日期：1995-11-01 00:00:00

abstract：:To investigate autonomic nervous function during upper gastrointestinal endoscopy, we analyzed R-R interval variability from electrocardiograms obtained during endoscopy. Holter electrocardiogram recordings were made before and after premedication, and during endoscopy. Time- and frequency-domain analyses of heart rat...

journal_title：Journal of gastroenterology

authors： Hayashi T,Nomura M,Honda H,Tezuka K,Torisu R,Takeuchi Y,Nakaya Y,Ito S

更新日期：2000-01-01 00:00:00