Propofol preserves the viability of isolated rat hepatocyte suspensions under an oxidant stress.

abstract：:The acute central nervous and cardiovascular effects of the local anesthetics ropivacaine and bupivacaine were compared in 12 volunteers in a randomized double-blind manner with use of intravenous infusions at a rate of 10 mg/min up to a maximal dose of 150 mg. The volunteers were all healthy men. They were familiariz...

journal_title：Anesthesia and analgesia

authors： Scott DB,Lee A,Fagan D,Bowler GM,Bloomfield P,Lundh R

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:Regional anesthesia is increasingly used in pediatric patients to provide postoperative analgesia and to supplement intraoperative anesthesia. The Pediatric Regional Anesthesia Network was formed to obtain highly audited data on practice patterns and complications and to facilitate collaborative research in ...

journal_title：Anesthesia and analgesia

authors： Polaner DM,Taenzer AH,Walker BJ,Bosenberg A,Krane EJ,Suresh S,Wolf C,Martin LD

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:An anesthesia department implemented scheduling of anesthetics outside of operating rooms (non-OR) by clerks and nurses from other departments using its hospital's enterprise-wide scheduling system. METHODS:Observational studies chronicled the change over 2 yr as non-OR time was allocated by specialty, and ...

journal_title：Anesthesia and analgesia

authors： Dexter F,Xiao Y,Dow AJ,Strader MM,Ho D,Wachtel RE

更新日期：2007-12-01 00:00:00

abstract：:Computer simulations for the technique of estimating minimum alveolar anesthetic concentration (MAC) in patients (quantal design) suggest that incremental concentration changes and the number of crossovers affect MAC. We hypothesized that these variables may also apply to estimating MAC in rats (bracketing design). Th...

journal_title：Anesthesia and analgesia

authors： Leon A,Mayzler O,Benifla M,Semionov M,Fuxman Y,Eilig I,Passuga V,Doitchinova MK,Gurevich B,Artru AA,Shapira Y

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Postoperative sore throat (POST) is not uncommon after general anesthesia with a supraglottic airway (SGA) device. Although it was reported that some pharmacological and nonpharmacological measures can reduce POST, because of limitations and variable success rates, we need to find a simpler and more effectiv...

journal_title：Anesthesia and analgesia

authors： Wang T,Wang Q,Zhou H,Huang S

更新日期：2020-12-01 00:00:00

abstract：:Several federal agencies have recently noted that the United States is in the midst of an unprecedented "opioid epidemic," with an increasing number of opioid-related overdoses and deaths. Providers currently face 3 population-level, public health challenges in providing optimal perioperative pain care: (1) the contin...

journal_title：Anesthesia and analgesia

authors： Vetter TR,Kain ZN

更新日期：2017-11-01 00:00:00

abstract：:In a laboratory experiment, the expected analgesic action of 33% nitrous oxide was reversed by creating the expectancy of heightened awareness of bodily sensations. Pain threshold and tolerance of electrical tooth-pulp stimulation were significantly reduced. Results from a control study gave us a basis for comparison ...

journal_title：Anesthesia and analgesia

authors： Dworkin SF,Chen AC,LeResche L,Clark DW

更新日期：1983-12-01 00:00:00

abstract：UNLABELLED:We performed in vitro studies to investigate the potential interaction of benzodiazepines with cloned human opioid receptor subtypes. Midazolam, chlordiazepoxide, and diazepam directly displaced [(3)H]-diprenorphine binding from kappa and delta receptors, but not mu receptors, whereas flumazenil was inactive...

journal_title：Anesthesia and analgesia

authors： Cox RF,Collins MA

更新日期：2001-08-01 00:00:00

abstract：:Alfentanil causes cardiac stimulation or depression in intact animals and in clinical practice; there is no information concerning its direct effects on the heart. Therefore, we studied the effects of alfentanil on isolated cardiac tissues from young adult rabbits. The right atrium with sinoatrial node (SA node) was b...

journal_title：Anesthesia and analgesia

authors： Zhang CC,Su JY,Calkins D

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:Postoperative delirium is an important problem for surgical inpatients and was the target of a multidisciplinary quality improvement project at our institution. We developed and tested a semiautomated delirium risk stratification instrument, Age, WORLD backwards, Orientation, iLlness severity, Surgery-specif...

journal_title：Anesthesia and analgesia

authors： Whitlock EL,Braehler MR,Kaplan JA,Finlayson E,Rogers SE,Douglas V,Donovan AL

更新日期：2020-12-01 00:00:00

abstract：UNLABELLED:Percutaneous needle liver biopsy is an important procedure for the diagnosis and evaluation of liver disease and is frequently associated with pain. In this prospective study, we investigated the prevalence and characteristics of this pain syndrome. Fifty-four subjects, who underwent liver biopsy under ultra...

journal_title：Anesthesia and analgesia

authors： Eisenberg E,Konopniki M,Veitsman E,Kramskay R,Gaitini D,Baruch Y

更新日期：2003-05-01 00:00:00

abstract：:Preoperative local anesthetic blockade of somatosensory pathways involved with skin incision and other noxious perioperative stimuli may "preempt" or attenuate the postoperative pain response. Since the Pfannenstiel incision lies within the L1 dermatome, bilateral ilioinguinal, iliohypogastric nerve blocks (IINBs) sho...

journal_title：Anesthesia and analgesia

authors： Huffnagle HJ,Norris MC,Leighton BL,Arkoosh VA

更新日期：1996-01-01 00:00:00

abstract：:Antagonists of the serotonergic 5-hydroxytryptamine 3A receptor (5-HT(3A)R) and muscle nicotinic acetylcholine receptors (nAChR) are widely used in anesthesia practice. Both 5-HT(3A)R and nAChR are ligand-gated ion channels with known pharmacological overlap between some of their agonists and antagonists. We studied t...

journal_title：Anesthesia and analgesia

authors： Paul M,Callahan R,Au J,Kindler CH,Yost CS

更新日期：2005-09-01 00:00:00

abstract：UNLABELLED:Acute withdrawal syndromes, including agitation and a long weaning time, are common adverse effects after long-term sedation with midazolam. We performed this study to determine whether the sequential use of midazolam and propofol could reduce adverse effects as compared with midazolam alone. We studied 26 p...

journal_title：Anesthesia and analgesia

authors： Saito M,Terao Y,Fukusaki M,Makita T,Shibata O,Sumikawa K

更新日期：2003-03-01 00:00:00

abstract：:There are limited and conflicting data on how a confirmatory step using high-dose heparin can improve diagnostic specificity of the antiplatelet factor 4/heparin enzyme immunoassay for heparin-induced thrombocytopenia (HIT). We investigated sera from a recently published study on cardiac surgery patients and found tha...

journal_title：Anesthesia and analgesia

authors： Selleng S,Schreier N,Wollert HG,Greinacher A

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Skeletal muscle failure in critical illness (intensive care unit-acquired weakness) is a well-known complication developing early during intensive care unit stay. However, muscle weakness during the perioperative setting has not yet been investigated. METHODS:We performed a subgroup investigation of a prosp...

journal_title：Anesthesia and analgesia

authors： Lachmann G,Mörgeli R,Kuenz S,Piper SK,Spies C,Kurpanik M,Weber-Carstens S,Wollersheim T,BIOCOG Consortium.

更新日期：2020-02-01 00:00:00

abstract：:If there is a genetic predisposition to excessive bleeding, there should be an association in excessive blood loss between multiple cardiac surgeries. We retrospectively determined in 174 patients the association of excessive bleeding between 2 cardiac surgeries with cardiopulmonary bypass between January 19, 1990 and...

journal_title：Anesthesia and analgesia

authors： Nuttall GA,Henderson N,Quinn M,Blair C,Summers L,Williams BA,Oliver WC,Santrach PJ

更新日期：2006-04-01 00:00:00

abstract：:Epidural anesthesia may be performed as a single injection or by staged doses. Thirty patients undergoing primary total hip replacement were randomly assigned to have epidural anesthesia using a single injection or a staged technique with 25 mL of 0.75% bupivacaine. Arterial plasma bupivacaine concentrations were sign...

journal_title：Anesthesia and analgesia

authors： Sharrock NE,Mineo R,Stanton J,Ennis WJ 3rd,Urmey WF,Arthur GR

更新日期：1994-08-01 00:00:00

abstract：:In a porcine model of uncontrolled hemorrhagic shock, we evaluated the effects of fluid resuscitation versus arginine vasopressin (AVP) combined with hypertonic-hyperoncotic hydroxyethyl starch solution (HHS) on cerebral perfusion pressure (CPP) and on cerebral metabolism using intracerebral microdialysis. Sixteen ane...

journal_title：Anesthesia and analgesia

authors： Meybohm P,Cavus E,Bein B,Steinfath M,Brand PA,Scholz J,Dörges V

更新日期：2006-10-01 00:00:00

abstract：:This study was undertaken to compare the antinociceptive and behavioral effects of intrathecally administered opiates, alpha-2-adrenergic agonists, and local anesthetics injected by lumbar puncture in the mouse and rat. Antinociception was determined by observing the response to a clamp applied to the tail (Haffner te...

journal_title：Anesthesia and analgesia

authors： Ossipov MH,Suarez LJ,Spaulding TC

更新日期：1988-07-01 00:00:00

abstract：:Isoproterenol 5 micrograms may be an effective marker of accidental intravascular injection in women in labor; however, before isoproterenol can be incorporated in routinely used epidural test doses, the safety and usefulness should be determined in an animal model. This study was designed to examine the hemodynamic e...

journal_title：Anesthesia and analgesia

authors： Marcus MA,Vertommen JD,Van Aken H,Wouters PF

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Patients with lung failure who undergo prone positioning often receive extended hemodynamic monitoring. We investigated the influence of modified prone positioning (135°) on the accuracy of pulse contour-derived calibrated cardiac index (CIPC) and uncalibrated cardiac index (CIVIG) in this patient population...

journal_title：Anesthesia and analgesia

authors： Grensemann J,Bruecken U,Treszl A,Wappler F,Sakka SG

更新日期：2013-04-01 00:00:00

abstract：:Because deviations from the Meyer-Overton rule may provide insights into the attributes of the anesthetic site of action, we characterized the solubility of the n-alkanes in various hydrophobic solvents (n-tetradecane, olive oil, n-octanol, and lecithin) as well as saline using variations on standard techniques. Incre...

journal_title：Anesthesia and analgesia

authors： Taheri S,Laster MJ,Liu J,Eger EI 2nd,Halsey MJ,Koblin DD

更新日期：1993-07-01 00:00:00

abstract：UNLABELLED:Pain complicates the recovery process after ambulatory surgery. We surveyed 175 ambulatory surgery patients to determine pain severity, analgesic use, relationship of pain to duration of recovery, and the relative importance of various factors to predicting these outcomes. Multivariate regression analysis wa...

journal_title：Anesthesia and analgesia

authors： Pavlin DJ,Chen C,Penaloza DA,Polissar NL,Buckley FP

更新日期：2002-09-01 00:00:00

abstract：:Stellate ganglion block (SGB) is an established procedure for the diagnosis and treatment of chronic pain. SGB results in an acute sympathetic denervation of a part of the left ventricular (LV) wall innervated by the blocked ganglion, which may impair regional contractility. The resulting imbalance of myocardial contr...

journal_title：Anesthesia and analgesia

authors： Schlack W,Schäfer S,Thämer V

更新日期：1994-12-01 00:00:00

abstract：UNLABELLED:We examined how to program an operating room (OR) information system to assist the OR manager in deciding whether to move the last case of the day in one OR to another OR that is empty to decrease overtime labor costs. We first developed a statistical strategy to predict whether moving the case would decreas...

journal_title：Anesthesia and analgesia

authors： Dexter F

更新日期：2000-10-01 00:00:00

abstract：IMPLICATIONS:Clinical productivity measurements that account for differences in clinical settings and concurrencies provided more precise comparisons between two anesthesiology groups. The data show that different concurrencies confound the current industry standard, "per full-time equivalent" measurements, whereas "pe...

journal_title：Anesthesia and analgesia

authors： Abouleish AE,Prough DS,Zornow MH,Lockhart A,Abate JJ,Hughes J

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Transversus abdominis plane (TAP) block and local anesthetic wound infiltration provide analgesia after cesarean delivery. Studies comparing the 2 techniques are scarce, with conflicting results. This double-blind, randomized controlled trial aimed to compare bilateral ultrasound-guided TAP block with single...

journal_title：Anesthesia and analgesia

authors： Tawfik MM,Mohamed YM,Elbadrawi RE,Abdelkhalek M,Mogahed MM,Ezz HM

更新日期：2017-04-01 00:00:00

abstract：:We studied 60 nonophthalmologic patients, allocated to six treatment groups, to assess the effects of atracurium and vecuronium on intraocular pressure (IOP). All patients had IOP measured while awake, using pneumotonometry. In group 1, anesthesia was induced with thiopental, 5 mg/kg, and maintained with N2O, 70% in O...

journal_title：Anesthesia and analgesia

authors： Schneider MJ,Stirt JA,Finholt DA

更新日期：1986-08-01 00:00:00

abstract：:The rate of hydrolysis of chloroprocaine by human serum was studied in the presence and absence of a number of aminde local anesthetics and their metabolites. Bupivacaine (2.4 microgram/ml) and etidocaine (2.3 microgram/ml) caused 38% and 21% inhibition respectively of the rate of chloroprocaine hydrolysis. Circulatin...

journal_title：Anesthesia and analgesia

authors： Lalka D,Vicuna N,Burrow SR,Jones DJ,Ludden TM,Haegele KD,McNay JL

更新日期：1978-09-01 00:00:00