Relationship of worry to immune sequelae of the Northridge earthquake.

Abstract:

:Worry is a cognitive activity in which potential problems are anticipated and enumerated in an attempt to control the future. Worry has been associated with dysregulation of the autonomic nervous system, which may extend to the immune system. The relationship between trait worry and immune parameters was investigated at three follow-up points after the Northridge earthquake in a sample of 47 hospital employees. Participants with scores above the median on a trait worry measure had fewer natural killer cells than participants with worry scores below the median and controls. This effect was not mediated by intrusive thoughts, avoidance, anxious mood, or health behavior. These results suggest that worry may have a detrimental effect on the regulation of natural killer cells during stress. This effect may be due to differences in autonomic responsiveness associated with worry.

journal_name

J Behav Med

authors

Segerstrom SC,Solomon GF,Kemeny ME,Fahey JL

doi

10.1023/a:1018732309353

subject

Has Abstract

pub_date

1998-10-01 00:00:00

pages

433-50

issue

5

eissn

0160-7715

issn

1573-3521

journal_volume

21

pub_type

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