Abstract：
:Pyruvate and dihydroxyacetone are three carbon compounds that when infused directly into the blood or taken orally produce strong metabolic effects. When chronically fed to animals as part of their diet, pyruvate plus dihydroxyacetone reduce the rate of weight gain and body fat content during growth. These alterations in growth pattern appear to be the result of an increased loss of calories as heat at the expense of storage of lipid. Pyruvate-dihydroxyacetone supplementation has also been found to improve the insulin sensitivity of insulin resistant rats and reduce plasma cholesterol levels induced by a high cholesterol diet as well as lower blood pressure and heart rate in obese individuals. When infused in rats during prolonged treadmill running, pyruvate reduced run time to exhaustion by approximately 67%. However, when provided as an oral supplement for several days, it has enhanced aerobic endurance capacity. The mechanism of action is unclear, but available data suggest that the increase in performance following pyruvate-dihydroxyacetone supplementation may be a result of an increased reliance on blood glucose, thus sparing muscle glycogen. In summary, chronic supplementation of pyruvate-dihydroxyacetone may be beneficial from a preventive medicine prospective as well as for certain athletic endeavors.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Ivy JLdoi
10.1097/00005768-199806000-00010subject
Has Abstractpub_date
1998-06-01 00:00:00pages
837-43issue
6eissn
0195-9131issn
1530-0315journal_volume
30pub_type
杂志文章,评审abstract：:Ten experienced weight lifters were studied to determine the influence of strenuous, free-weight, squat lift exercise on changes in plasma volume, mean arterial pressure, and the rate pressure product. After a 40-min postural adjustment prior to upright exercise, each subject completed eight sets of eight repetitions ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1987-10-01 00:00:00
abstract：PURPOSE:Aerobic training (AT) and high-intensity intermittent training (HIIT) reduce arterial stiffness, whereas resistance training (RT) induces deterioration of or no change in arterial stiffness. However, the molecular mechanism of these effects of different exercise modes remains unclear. This study aimed to clarif...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0000000000001567
更新日期：2018-06-01 00:00:00
abstract：:We provide an updated version of the Compendium of Physical Activities, a coding scheme that classifies specific physical activity (PA) by rate of energy expenditure. It was developed to enhance the comparability of results across studies using self-reports of PA. The Compendium coding scheme links a five-digit code t...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200009001-00009
更新日期：2000-09-01 00:00:00
abstract：:Ten subjects were studied to determine within-subject variance (Swi2), and its components, biovariability (Si2) and technological error (Se2) of residual lung volume (RLV). Each subject's RLV was determined 18 times using the oxygen dilution method (O2D) over a 5-day period. Se2 was measured using a 9.0 l spirometer a...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1986-08-01 00:00:00
abstract：UNLABELLED:Exercise increases methionine metabolism, which also increases its amino acid metabolic intermediate, homocysteine (Hcy). High Hcy levels increase cardiovascular disease (CVD) risk, whereas B-vitamins (folate, vitamins B6, and B12) can reduce Hcy. Research exploring the relationship between exercise and Hcy ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e31817f36f9
更新日期：2008-11-01 00:00:00
abstract：:Cyclic AMP increases in liver during exercise, the magnitude of the increase being dependent on duration and intensity of the exercise. Within limits, the increase in cAMP is closely correlated with the rate of glycogenolysis and with the exercise intensity. It is unlikely that epinephrine is involved in determining c...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：
更新日期：1988-12-01 00:00:00
abstract：:Vigorous exercise is associated with a sensation of well-being, and this subjective state has been objectively quantified with psychometric, cardiovascular, and neurophysiological data. Reductions in state anxiety have been demonstrated to follow acute physical activity, and this response persists for 2-5 h. Chronic p...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：
更新日期：1985-02-01 00:00:00
abstract：PURPOSE:The study's purpose was to examine the effects of a short-term period with intensified training or training cessation of trained soccer players on VO(2) kinetics at 75% maximal aerobic speed, oxidative enzymes, and performance in repeated high-intensity exercise. METHODS:After the last match of the season, 18 ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e318211c01a
更新日期：2011-09-01 00:00:00
abstract：PURPOSE:Aerodynamic drag plays an important role in performance for athletes practicing sports that involve high-velocity motions. In giant slalom, the skier is continuously changing his/her body posture, and this affects the energy dissipated in aerodynamic drag. It is therefore important to quantify this energy to un...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3182443315
更新日期：2012-06-01 00:00:00
abstract：PURPOSE:Exercise improves the diagnostic performance of ankle-to-brachial index (ABI) in the detection of exercise-induced arterial endofibrosis (EIAE). Pressure values for all four limbs are required to calculate ABI, but rapid systemic pressure changes occur during the recovery period from exercise. We checked whethe...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.mss.0000232021.21361.9c
更新日期：2006-11-01 00:00:00
abstract：:Acute aerobic exercise improves mood and activates the endocannabinoid (eCB) system in physically active individuals; however, both mood and eCB responses to exercise may vary based on habitual levels of physical activity. PURPOSE:This study aimed to examine eCB and mood responses to prescribed and preferred exercise...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000001276
更新日期：2017-08-01 00:00:00
abstract：PURPOSE:The purpose of the current study was to investigate the associations between the GNB3 C825T polymorphism, body fatness and fitness, and blood pressure in a sample of young Korean men. METHODS:A total of 282 apparently healthy Korean men (nonobese N = 152, obese N = 130) aged 19-33 yr participated in the study....
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.mss.0000170096.96662.05
更新日期：2005-07-01 00:00:00
abstract：:The objective of this study was to design and validate a working tool for the objective evaluation of daily energy expenditure (DEE) by means of a simple, noninvasive method: the QAPSE (Saint-Etienne Physical Activity Questionnaire), a questionnaire about physical activity (PA) over a period of 7 d (168 h). This eight...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1993-12-01 00:00:00
abstract：PURPOSE:To examine the relationship between physical activity and levels of plasma lipid peroxides, superoxide dismutase in erythrocytes (SOD), and glutathione peroxidase (GSH-Px) in whole blood activities. METHODS:Cross-sectional study in 488 Spanish women. Two categories of leisure time physical activity were define...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200205000-00014
更新日期：2002-05-01 00:00:00
abstract：PURPOSE:An augmented pulmonary artery wedge pressure (PAWP) response may explain exercise intolerance in some humans. However, routine use of exercise hemodynamic testing is limited by a lack of data from normal older men and women. Our objective was to evaluate the exercise PAWP response and the potential for sexual d...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000001227
更新日期：2017-07-01 00:00:00
abstract：PURPOSE:To describe the mood profile of an America's Cup sailing team during competition and to evaluate the influence of previous injuries occurrence and intensity of physical work on the boat upon mood state. Relationships between mood domains and metabolic markers of muscle damage were also investigated. METHODS:A ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181cd5cb9
更新日期：2010-07-01 00:00:00
abstract：PURPOSE:The purpose of this study was to determine whether muscle power, activation time, and neuromuscular stimulation are related to physical activity patterns in older women. METHODS:Forty women (65-84 yr) were assigned to high-active (HA) and low-active (LA) groups on the basis of a historical activity questionnai...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/mss.0b013e318074ccd9
更新日期：2007-09-01 00:00:00
abstract：PURPOSE:This study examined whether plasma total glutathione levels could explain the intersubject variability in the creatine kinase (CK) response to eccentric exercise. We hypothesized that the increase in plasma CK activity after eccentric exercise would be lower for individuals with low plasma total glutathione (<2...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.MSS.0000069553.47739.36
更新日期：2003-06-01 00:00:00
abstract：PURPOSE:The purpose of this study was to examine the relative association of physical activity, cardiorespiratory fitness (CRF), and adiposity with C-reactive protein (CRP) in prepubescent children. METHODS:Forty-five prepubescent children (age = 9.4 ± 1.6 yr; 26 boys) were assessed for adiposity (percent fat) via dua...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181e0355e
更新日期：2010-11-01 00:00:00
abstract：:Our understanding of the responses of men and women to cold stress is extremely limited. Various scientists have suggested that there could be gender differences in thermoregulatory responses due to sexual dimorphism in body fatness and its distribution, in body surface area, and in mass. In addition, there are also s...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：10.1249/00005768-198810001-00017
更新日期：1988-10-01 00:00:00
abstract：PURPOSE:This study determined the dose-response effects of inhaled salbutamol (SAL) on time-trial performance and urine concentrations of SAL (cSAL). METHODS:Nonasthmatic, trained male cyclists and triathletes (N = 37) were studied. Day 1 consisted of screening for airway hyperresponsiveness, using a eucapnic voluntar...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1249/mss.0b013e3181591df7
更新日期：2008-01-01 00:00:00
abstract：PURPOSE:The purpose of this study was to examine and quantify the effect of repeated driving stints on the physiologic, metabolic, and hormonal responses of three professional endurance driver-athletes. METHODS:Core body temperature, HR, and physiological strain index were recorded during the Rolex 24 Hours of Daytona...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002507
更新日期：2020-09-01 00:00:00
abstract：PURPOSE:This study tested the hypothesis that the magnitude of cardiovascular (CV) drift and decrease in maximal oxygen uptake (V[spacing dot above]O2max) would be greater at 35 degrees C than at 22 degrees C. METHODS:The increase in HR and decrease in stroke volume (SV) between 15 and 45 min of cycling at 59.2 +/- 1....
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181666ed7
更新日期：2008-06-01 00:00:00
abstract：PURPOSE:Previous studies have suggested that higher levels of physical activity may lower lung cancer risk; however, few prospective studies have evaluated lung cancer mortality in relation to cardiorespiratory fitness (CRF), an objective marker of recent physical activity habits. METHODS:Thirty-eight thousand men, ag...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181c47b65
更新日期：2010-05-01 00:00:00
abstract：PURPOSE:For treatment of various knee disorders, muscles are trained in open or closed kinetic chain tasks. Coordination between the heads of the quadriceps muscle is important for stability and optimal joint loading for both the tibiofemoral and the patellofemoral joint. The aim of this study was to examine whether th...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.MSS.0000099107.03704.AE
更新日期：2003-12-01 00:00:00
abstract：PURPOSE:The Compendium of Physical Activities was developed to enhance the comparability of results across studies using self-report physical activity (PA) and is used to quantify the energy cost of a wide variety of PA. We provide the second update of the Compendium, called the 2011 Compendium. METHODS:The 2011 Compe...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e31821ece12
更新日期：2011-08-01 00:00:00
abstract：:The purpose of this study was to determine whether efferent sympathetic nerve activity is different to resting skeletal muscles from the exercising and nonexercising limb. MSNA was measured by microneurography in both legs (peroneal nerve) in six subjects during 2 min of unilateral isometric knee extension (IKE; 10-30...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1995-02-01 00:00:00
abstract：UNLABELLED:It is often reported that females lose less body weight than males do in response to exercise. These differences are suggested to be a result of females exhibiting a stronger defense of body fat and a greater compensatory appetite response to exercise than males do. PURPOSE:This study aimed to compare the e...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0b013e31826ced79
更新日期：2013-02-01 00:00:00
abstract：INTRODUCTION:Although both humans and quadrupeds frequently coordinate breathing and limb movement during running, early studies in humans focused on how increased breathing flexibility in humans allowed for relaxed or even transient coordination during locomotion. This difference was used to explain why quadrupeds had...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e318248d907
更新日期：2012-07-01 00:00:00
abstract：PURPOSE:To test our hypothesis that differences in urinary calcium excretion among blacks and whites may be secondary to ethnic variations in acid (H(+)) metabolism and to prove that increases in titratable acid excretion would be found among individuals predisposed to the development of stress fractures. METHODS:We a...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章
doi：10.1097/00005768-200202000-00018
更新日期：2002-02-01 00:00:00
