Abstract:
:Cyclic AMP increases in liver during exercise, the magnitude of the increase being dependent on duration and intensity of the exercise. Within limits, the increase in cAMP is closely correlated with the rate of glycogenolysis and with the exercise intensity. It is unlikely that epinephrine is involved in determining cAMP concentration in liver during exercise. Adrenodemedullated rats show no impairment in exercise-induced liver glycogenolysis or in the increase in cAMP. When epinephrine is infused at different rates into exercising rats, liver cAMP appears to be unrelated to plasma epinephrine. The rise in plasma glucagon is likely responsible for the increase in hepatic cAMP during exercise. The increase in cAMP is apparently necessary for maintaining low levels of fructose-2,6-bisphosphate (the activator of PFK-1 and inhibitor of fructose-1,6-bisphosphate) in liver. The low fructose-2,6-bisphosphate concentration would be expected to result in an increase rate of gluconeogenesis during exercise.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Winder WWsubject
Has Abstractpub_date
1988-12-01 00:00:00pages
551-9issue
6eissn
0195-9131issn
1530-0315journal_volume
20pub_type
杂志文章,评审abstract::Existing cross-sectional studies on plasma catecholamine activity provide no support for the concept that a markedly high level of aerobic fitness modifies sympathoadrenal response to an acute psychological challenge in humans. In contrast, compromised sympathetic nervous system activity has been observed in individua...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:
更新日期:1991-07-01 00:00:00
abstract:PURPOSE:A 20-d 6 degrees head-down tilt bed rest project was conducted to evaluate the effect of dynamic leg press and plantar flexion resistance training on muscle size and function in human plantar flexors (PF) throughout the prolonged bed rest. METHODS:Twelve healthy men participated in this study and were divided ...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1249/01.MSS.0000058367.66796.35
更新日期:2003-04-01 00:00:00
abstract:PURPOSE:This study aimed to examine the effect of altering osmolality or adding sodium alginate and pectin to a concentrated carbohydrate (CHO) beverage on gastric-emptying (GE) rate. METHODS:Boluses (500 mL) of three drinks were instilled double blind in eight healthy men while seated, GE was measured using the doubl...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002301
更新日期:2020-08-01 00:00:00
abstract::Endocrine effects of self-administration of high doses of anabolic steroids and testosterone were investigated in five power athletes during 26 wk of training, and for the following 12-16 wk after drug withdrawal. After 26 wk of anabolic steroid and testosterone administration, serum testosterone concentrations had in...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1985-06-01 00:00:00
abstract::By placing the muscles of the take-off leg in faster eccentric or slower concentric conditions, a high jumper can increase the ground reaction force and the height of the jump. Film analysis of seven high jumpers showed that the radial velocity of the center of mass with respect to the supporting foot was more negativ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/00005768-198806000-00014
更新日期:1988-06-01 00:00:00
abstract::The immune response was assessed in 13 competitive bodybuilders self-administering anabolic-androgenic steroids and ten competitive bodybuilders not administering these drugs. Laboratory assessment included the number and relative distribution of T-cells, T-helper/inducer cells, T-cytotoxic/suppressor cells, activated...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:
更新日期:1989-08-01 00:00:00
abstract:PURPOSE:The purpose of this study was to investigate the effect of acute ingestion of modafinil (M) on time to exhaustion during high-intensity exercise. Modafinil (M) is a psychostimulant developed to treat narcolepsy, with "arousal" properties attributed to an increased release of dopamine in the CNS. Because other s...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:10.1249/01.mss.0000128146.12004.4f
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of chronic moderate-intensity exercise upon the alterations of immune system cell function induced by energy restriction. METHODS:Forty male Wistar rats were randomly assigned to the following groups: sedentary animals fed ad libitum (SF, N = 10) or submitted to energy restriction (SER...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000147626.32295.38
更新日期:2004-12-01 00:00:00
abstract:PURPOSE:beta2 adrenergic agonists are widely used as doping agents. Their side effects on bone, especially microarchitecture, remain unknown. The purpose of this study was to evaluate the effects of chronic clenbuterol and salbutamol treatment on bones of growing rats. METHODS:Twelve-week-old Wistar female rats were d...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000177592.82507.95
更新日期:2005-09-01 00:00:00
abstract:PURPOSE:sarcopenia plays a principal role in the pathogenesis of frailty and functional impairment that occur with aging. There are few published accounts that examine the overall benefit of resistance exercise (RE) for lean body mass (LBM) while considering a continuum of dosage schemes and/or age ranges. Therefore, t...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,meta分析,评审
doi:10.1249/MSS.0b013e3181eb6265
更新日期:2011-02-01 00:00:00
abstract:PURPOSE:Evasive sidestepping during sports commonly results in noncontact anterior cruciate ligament injuries. Sidestepping in response to different simple visual stimuli has been studied previously but never investigated using quasi-game-realistic visual conditions. We compared the biomechanics of high-level and low-l...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e318290c28a
更新日期:2013-09-01 00:00:00
abstract:PURPOSE:The aim of this study was to test whether a tidally ventilated homogeneous lung model can correctly describe arterial and end-tidal gas partial pressures and thus the difference in end-tidal and arterial gas partial pressures at rest and during exercise. METHODS:The implemented mathematical modeling described ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200204000-00010
更新日期:2002-04-01 00:00:00
abstract:PURPOSE:Studies have shown that absolute intensity of physical activity is associated with reduced risk of preeclampsia. This analysis was performed to examine whether relative intensity may also be related to preeclampsia risk. METHODS:Using data from a case-control study conducted from 1998 to 2002, the authors asse...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000175862.41620.41
更新日期:2005-11-01 00:00:00
abstract:PURPOSE:To determine the prevalence of full-thickness focal chondral defects in the athlete's knee. METHODS:We conducted a systematic review of multiple databases, evaluating studies of the prevalence of articular cartilage defects in athletes. Because of the heterogeneity of data, a meta-analysis could not be perform...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:10.1249/MSS.0b013e3181d9eea0
更新日期:2010-10-01 00:00:00
abstract:PURPOSE:This study evaluated the predictive validity of three previously published ActiGraph energy expenditure (EE) prediction equations developed for children and adolescents. METHODS:A total of 45 healthy children and adolescents (mean age: 13.7 +/- 2.6 yr) completed four 5-min activity trials (normal walking, bris...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000183848.25845.e0
更新日期:2006-02-01 00:00:00
abstract::Previous studies have suggested that, for the same power output, arm exercise requires higher oxygen uptake (VO2), carbon dioxide output (VCO2), and ventilation (VE) than leg exercise and that response kinetics are slower. To evaluate these differences, four healthy subjects performed a total of 95 arm cranking tests....
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1992-12-01 00:00:00
abstract:PURPOSE:Arterial distensibility decreases with age. This decrease may be associated with the initiation and/or progression of hypertension and atherosclerosis and may be attenuated by positive lifestyle habits, including habitual physical activity. We tested the hypothesis that self-reported sport, leisure, and work ph...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200112000-00014
更新日期:2001-12-01 00:00:00
abstract:PURPOSE:The effects of chronic exercise training on the expression of heat shock protein (HSP) in skeletal muscle of senescent animals are unknown. Therefore, the purpose of this study was to investigate the effects of chronic exercise training on skeletal muscle HSP expression in both young and old rats. METHODS:Youn...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200105000-00008
更新日期:2001-05-01 00:00:00
abstract::To study effort tolerance in elderly women with different physical activity backgrounds, 52 physically active (PA) and 42 sedentary control women (CO) aged 66-85 yr were assigned to perform cycle ergometer exercise to their volitional maximum. Oxygen uptake, respiratory exchange ratio (RER), heart rate, work power, an...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199801000-00024
更新日期:1998-01-01 00:00:00
abstract::Nine men participated in an exercise program (five days a week for 10 weeks) that was designed to strengthen the quadriceps muscles. This study was undertaken to determine if heavy resistance training results in an increase in endurance, Vo2max and whether the differences that are normally observed during bicycle and ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract:PURPOSE:This study examined whether plasma total glutathione levels could explain the intersubject variability in the creatine kinase (CK) response to eccentric exercise. We hypothesized that the increase in plasma CK activity after eccentric exercise would be lower for individuals with low plasma total glutathione (<2...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.MSS.0000069553.47739.36
更新日期:2003-06-01 00:00:00
abstract:PURPOSE:We investigated the knee-extensor torque at which reoxygenation (inflow of arterial blood) during an isometric contraction stopped, whether this torque depended on maximal torque capacity (MTC), and whether there were differences among the synergists. METHODS:Isometric knee-extension torque was measured using ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/mss.0b013e31802dd3cc
更新日期:2007-03-01 00:00:00
abstract:INTRODUCTION:Slow gait predicts many adverse clinical outcomes in old adults, but the mechanisms of how power training can minimize the age-related loss of gait velocity is unclear. We examined the effects of 10 wk of lower extremity power training and detraining on healthy old adults' lower extremity muscle power and ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001082
更新日期:2017-01-01 00:00:00
abstract::Magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI) are new and powerful tools to study tissue biochemistry, and to provide precise anatomical visualization of soft tissue structures. This review focuses on the use of these techniques to study exercise-induced muscle injury. MRS measurements sho...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:
更新日期:1992-05-01 00:00:00
abstract:PURPOSE:Few epidemiological studies have been conducted among middle-aged women on long-term total and specific physical activity (PA) trends. We studied in a cross-sectional setting the relationship of self-reported total daily PA with age and calendar time. METHODS:In a population-based cohort of 38,988 women aged 4...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000185086.19220.b3
更新日期:2006-02-01 00:00:00
abstract::1) Many otherwise healthy runners are prevented from participating fully in their chosen endurance sport because of overuse injuries. 2) The most important risk factor for incurring an overuse injury is a training error, such as excessive mileage, sudden change in training distance or intensity, too much hard interval...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/00005768-199209001-00010
更新日期:1992-09-01 00:00:00
abstract::The purposes of this investigation were to compare selected gait parameters characteristic of running without respiratory apparatus on a treadmill (NOR) with those displayed while wearing a mouthpiece-breathing valve apparatus (MP) and while wearing a respiratory face mask (MASK), and to compare the running economy (R...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1993-02-01 00:00:00
abstract:INTRODUCTION:Increased sedentary behavior predicts greater cardiovascular morbidity and mortality and does so independently of physical activity (PA). This association is only partially explained by body mass index (BMI) and overall body fat, suggesting mechanisms besides general increased adiposity. The purpose of thi...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3182a77220
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:To examine the relationship between variable lower-limb coordination and shoulder joint kinetics and kinematics in the high-performance flat first serve in tennis. METHODS:Three-dimensional data describing three flat serve (FS) techniques, each executed with varying lower-limb involvement: foot-up (FU), foot-b...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/mss.0b013e31815c6d61
更新日期:2008-02-01 00:00:00
abstract::MRI is an excellent noninvasive method of diagnosing difficult shoulder problems. Although usually not needed for classic primary impingement syndrome or clinically obvious rotator cuff tears, MRI may be helpful in diagnosing secondary causes of impingement or in some cases involving partial rotator cuff tears. Some s...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:10.1097/00005768-199804001-00002
更新日期:1998-04-01 00:00:00