Abstract:
PURPOSE:sarcopenia plays a principal role in the pathogenesis of frailty and functional impairment that occur with aging. There are few published accounts that examine the overall benefit of resistance exercise (RE) for lean body mass (LBM) while considering a continuum of dosage schemes and/or age ranges. Therefore, the purpose of this meta-analysis was to determine the effects of RE on LBM in older men and women while taking these factors into consideration. METHODS:this study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses recommendations. Randomized controlled trials and randomized or nonrandomized studies among adults ≥ 50 yr were included. Heterogeneity between studies was assessed using the Cochran Q and the I statistics, and publication bias was evaluated through physical inspection of funnel plots as well as formal rank-correlation statistics. Mixed-effects meta-regression was incorporated to assess the relationship between RE dosage and changes in LBM. RESULTS:data from 49 studies, representing a total of 1328 participants, were pooled using random-effect models. Results demonstrated a positive effect for LBM, and there was no evidence of publication bias. The Cochran Q statistic for heterogeneity was 497.8, which was significant (P < 0.01). Likewise, I was equal to 84%, representing rejection of the null hypothesis of homogeneity. The weighted pooled estimate of mean LBM change was 1.1 kg (95% confidence interval = 0.9-1.2 kg). Meta-regression revealed that higher-volume interventions were associated (β = 0.05, P < 0.01) with significantly greater increases in LBM, whereas older individuals experienced less increase (β = -0.03, P = 0.01). CONCLUSIONS:RE is effective for eliciting gains in LBM among aging adults, particularly with higher-volume programs. Findings suggest that RE participation earlier in life may provide superior effectiveness.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Peterson MD,Sen A,Gordon PMdoi
10.1249/MSS.0b013e3181eb6265subject
Has Abstractpub_date
2011-02-01 00:00:00pages
249-58issue
2eissn
0195-9131issn
1530-0315journal_volume
43pub_type
杂志文章,meta分析,评审abstract:OBJECTIVES:To examine if the associations between motor competence and physical activity and musculoskeletal fitness change over time, whether motor competence is associated with longitudinal trajectories of physical activity and fitness, and mediating pathways among these constructs across early childhood. METHODS:Fo...
journal_title:Medicine and science in sports and exercise
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abstract:OBJECTIVE:The accurate determination of limitations in physical activity is important in evaluating patients with heart failure and in assessing the efficacy of treatment. However, the conventional measures used to evaluate hemodynamics, functional class, and exercise capacity all have limitations. Our objective was to...
journal_title:Medicine and science in sports and exercise
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journal_title:Medicine and science in sports and exercise
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journal_title:Medicine and science in sports and exercise
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journal_title:Medicine and science in sports and exercise
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journal_title:Medicine and science in sports and exercise
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journal_title:Medicine and science in sports and exercise
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journal_title:Medicine and science in sports and exercise
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journal_title:Medicine and science in sports and exercise
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journal_title:Medicine and science in sports and exercise
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journal_title:Medicine and science in sports and exercise
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更新日期:2000-09-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
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journal_title:Medicine and science in sports and exercise
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199909000-00019
更新日期:1999-09-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:
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journal_title:Medicine and science in sports and exercise
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journal_title:Medicine and science in sports and exercise
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doi:
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