Mechanisms and patterns of blood lactate increase during exercise in man.

Abstract:

:The close balance between the O2 requirement to perform exercise and the O2 supply was analyzed. A non-uniform capillary PO2 can result in anaerobic metabolism in some muscle fibers despite an apparently adequate mean capillary PO2. The pattern of lactate increase for constant work rates and incremental exercise is described. Lactate increases without an increase in pyruvate at a threshold work rate above which the lactate/pyruvate ratio increases. The latter decreases immediately at the start to recovery. From simultaneous measurements of arterial lactate and pyruvate during exercise and recovery, we conclude that the lactate increase at the lactate threshold is consequent to a change in redox state rather than a mass action effect.

journal_name

Med Sci Sports Exerc

authors

Wasserman K,Beaver WL,Whipp BJ

doi

10.1249/00005768-198606000-00017

subject

Has Abstract

pub_date

1986-06-01 00:00:00

pages

344-52

issue

3

eissn

0195-9131

issn

1530-0315

journal_volume

18

pub_type

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