Abstract:
PURPOSE:The purpose of the current study was to investigate the associations between the GNB3 C825T polymorphism, body fatness and fitness, and blood pressure in a sample of young Korean men. METHODS:A total of 282 apparently healthy Korean men (nonobese N = 152, obese N = 130) aged 19-33 yr participated in the study. Body fatness and blood pressure were measured by using standardized protocols. The GNB3 C825T was genotyped by using polymerase chain reaction with restriction fragment length polymorphism. RESULTS:Univariate analyses of variance and Bonferroni post hoc tests showed that in the obese group only, TT homozygotes had a lower VO2max (P = 0.015 and 0.043, respectively) but higher resting systolic (P = 0.025 and < 0.001, respectively) and mean arterial blood pressures (P = 0.049 and 0.002, respectively) than CC homozygotes or CT heterozygotes. We further investigated possible interactions between group and genotype and found a significant interaction in SBP only (P = 0.037) between the group and genotype, even when controlling for age, BMI, and VO2max as potential confounding factors. Stepwise regression analyses showed that body mass index and GNB3 genotype were two independent predictors for the variations in systolic blood pressure and heart rate up to by 14.3 and 14.5%, respectively. In addition, waist-to-hip ratio explained an individual variation in mean arterial pressure (MAP) up to by 11.2%. CONCLUSION:The current findings of the study suggest that increased body fatness along with low cardiorespiratory fitness may magnify the genetic susceptibility of the GNB3 825T allele to elevated blood pressure in this study population.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Lee J,Lee S,Shin S,Kang HSdoi
10.1249/01.mss.0000170096.96662.05subject
Has Abstractpub_date
2005-07-01 00:00:00pages
1138-43issue
7eissn
0195-9131issn
1530-0315pii
00005768-200507000-00009journal_volume
37pub_type
杂志文章abstract:PURPOSE:To evaluate the effects of physical activity on bone mineral density, bone mineral content, and lean mass in postmenopausal, overweight/obese women. METHODS:We conducted a 12-month randomized controlled aerobic exercise intervention versus control in 173 sedentary, overweight/obese, postmenopausal women, aged ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/01.mss.0000227308.11278.d7
更新日期:2006-07-01 00:00:00
abstract::Walking is an important form of physical activity. It is practiced by people of nearly all ages, throughout the world. Walking is an integral part of life, and there is accumulating evidence that it is essential to good health. There are many ways to measure walking including pedometers, accelerometers, trail counters...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:10.1249/MSS.0b013e31817c699c
更新日期:2008-07-01 00:00:00
abstract:PURPOSE:The purpose of study was to determine whether quadriceps/patella and Achilles tendon length and flexibility of the knee extensors and plantar flexors are related to walking and running economy. METHODS:Twenty-one male distance runners were subjects. Quadriceps/patella and Achilles tendon length were measured b...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e318210464a
更新日期:2011-08-01 00:00:00
abstract::Increased vertical impact loading during running has been associated with a variety of running related injuries including stress fractures, patellofemoral pain, and plantar fasciitis. PURPOSE:The purpose of this study was to examine the acute and long-term effect of a gait retraining program aimed at teaching runners...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001710
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:Type 2 diabetes is associated with increased risk of cardiovascular disease and elevated C-reactive protein (CRP) levels. Aerobic exercise training has been shown to improve CRP; however, there are limited data evaluating the effect of other exercise training modalities (aerobic, resistance, or combination trai...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0b013e31824526cc
更新日期:2012-06-01 00:00:00
abstract::Recently, Sarna et al. (Med. Sci. Sports Exerc. 25:237-244, 1993) reported increased mean life expectancy in former world class athletes. Because lifestyle is associated with longevity, we have examined whether health habits of former Finnish male athletes (N = 1274; present mean age: 57.5, range: 36-94 yr) differed f...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/00005768-199402000-00013
更新日期:1994-02-01 00:00:00
abstract::Fatigue can be defined as the failure to maintain an expected power output. This is often an antecedent to some sports-related injury. It is important for those involved in physical performance to be familiar with the variety of mechanisms which can lead to fatigue. All too often, a single factor is described as the c...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:
更新日期:1990-08-01 00:00:00
abstract:PURPOSE:To examine the influence of two patellofemoral braces on pain response, patellar alignment, and patellofemoral joint contact area in persons with patellofemoral pain. METHODS:Fifteen women between the ages of 18 and 45 yr with a diagnosis of patellofemoral pain participated. After the assessment of pain respon...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000132376.50984.27
更新日期:2004-07-01 00:00:00
abstract:PURPOSE:The objective of this study is to determine the effects of a caffeine-containing energy drink on female volleyball players' performance. METHODS:Thirteen elite female volleyball players ingested 3 mg·kg of caffeine with an energy drink or the same drink without caffeine (placebo drink) in a double-blind and ra...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000000455
更新日期:2015-04-01 00:00:00
abstract::Although low back pain (LBP) is a widespread and disabling health problem, there is a lack of evidence based medicine with respect to its treatment and rehabilitation. A major reason for this is the poor understanding of the underlying mechanisms of the LBP syndromes. In an attempt to fill this gap, the present review...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:10.1097/00005768-200111000-00014
更新日期:2001-11-01 00:00:00
abstract:PURPOSE:To examine whether components of body composition (size, fat mass, and fat-free mass) were related to physical activity. METHODS:A random sample of 60 eligible sixth grade girls at each of 36 schools (six schools per region and six regions in total sample); complete measurements on 1,553 girls. Physical activi...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000222846.27380.61
更新日期:2006-06-01 00:00:00
abstract:PURPOSE:To test for relationships between objectively measured habitual physical activity and fundamental movement skills in a relatively large and representative sample of preschool children. METHODS:Physical activity was measured over 6 d using the Computer Science and Applications (CSA) accelerometer in 394 boys an...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1249/01.mss.0000159138.48107.7d
更新日期:2005-04-01 00:00:00
abstract:INTRODUCTION:Scientists and clinicians have attempted to identify and understand biomechanical factors that influence concussion likelihood. The effect of impact frequency to a given head location before the concussion has not been evaluated. The purpose of this study was to compare the frequency of impacts to a given ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000896
更新日期:2016-07-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001765
更新日期:2019-01-01 00:00:00
abstract::In embryonic chicken skeletal muscle, the presence of a ventricular myosin heavy chain (MHC) is demonstrated by reactivity with an anti-ventricular MHC antibody. Developmental repression of the ventricular MHC expression occurs earlier in embryonic fast twitch posterior latissimus dorsi (PLD) than in embryonic slow-to...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:
更新日期:1989-10-01 00:00:00
abstract:UNLABELLED:Several investigators have demonstrated that chronic eccentric leg cycling is an effective method for improving lower body neuromuscular function (e.g., quadriceps muscle size, strength, and mobility) in a variety of patient and athletic populations. To date, there are no reports of using eccentric arm cycli...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:10.1249/MSS.0b013e318269c79c
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:For treatment of various knee disorders, muscles are trained in open or closed kinetic chain tasks. Coordination between the heads of the quadriceps muscle is important for stability and optimal joint loading for both the tibiofemoral and the patellofemoral joint. The aim of this study was to examine whether th...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.MSS.0000099107.03704.AE
更新日期:2003-12-01 00:00:00
abstract:PURPOSE:To evaluate the relations between %HRmax, %HRR, %VO2max, and %VO2R in elite cyclists and to check whether the intensity scale recommended by ACSM in its 1998 position stand is also applicable to this specific population. METHODS:Twenty-six male elite road cyclists (25.1 +/- 0.7 yr, 71.0 +/- 1.2 kg, 70.9 +/- 1....
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000246996.63976.5f
更新日期:2007-02-01 00:00:00
abstract::Thirty-eight athletes with unilateral patellar tendinopathy (17 with a tendinopathy of the main body of the tendon, and 21 with an insertional tendinopathy) underwent ultrasound-guided multiple percutaneous longitudinal tenotomy under local anaesthetic infiltration after failure of conservative management. Thirty-four...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199911000-00003
更新日期:1999-11-01 00:00:00
abstract:INTRODUCTION/PURPOSE:To assess in men whether exercise affects the estimated age-related increase in adiposity, and contrariwise, whether age affects the estimated exercise-related decrease in adiposity. METHODS:Cross-sectional analyses of 64,911 male runners who provided data on their body mass index (97.6%) and wais...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000174894.05236.45
更新日期:2005-08-01 00:00:00
abstract::A biomechanical model of the ankle joint was developed and was used to predict the forces at the ankle during the stance phase of running. Measurements from five cadavers were averaged to obtain insertion points and directions of pull of equivalent tendons with respect to the assumed center of the ankle joint. A minim...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/00005768-198204000-00010
更新日期:1982-01-01 00:00:00
abstract:PURPOSE:Exercise training reduces pathological remodeling and improves cardiac function in ischemic heart failure; however, causal mechanisms underlying the cardiac benefits of exercise are poorly understood. Because opening of adenosine triphosphate (ATP)-sensitive K ⁺(KATP) channels protects the heart during myocardi...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000714
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:Skeletal muscle (SM), which is found mainly within the appendicular lean soft tissue (ALST) compartment, is a biological important body compartment. Simple and accurate methods to estimate both SM and ALST remain difficult to obtain. We aimed to develop and to cross-validate anthropometric models for ALST in at...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e31818ffe4b
更新日期:2009-04-01 00:00:00
abstract:PURPOSE:The purpose of the present study was to examine the effect of muscle activity level on serum creatine kinase (CK) activity after high-force eccentric exercise of the elbow flexors. METHODS:Twenty-six male volunteers were randomly assigned to one of three groups for a 4-d treatment period after exercise: immobi...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:10.1097/00005768-200009000-00011
更新日期:2000-09-01 00:00:00
abstract:PURPOSE:This study aimed to determine the effect of a caffeine-containing supplement on golf-specific performance and fatigue during a 36-hole competitive golf tournament. METHODS:Twelve male golfers (34.8 ± 13.9 yr, 175.9 ± 9.3 cm, 81.23 ± 13.14 kg) with a United States Golf Association handicap of 3-10 participated ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000000753
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:Female athletes often demonstrate changes in cardiac dimensions that are less prominent than in male athletes, and results from longitudinal studies are conflicting. The atrioventricular plane displacement (AVPD) in the heart is used as an index of left ventricular systolic function with the assumption that it ...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:10.1249/01.mss.0000145444.01292.3d
更新日期:2004-11-01 00:00:00
abstract:INTRODUCTION:The purpose of this study was to identify unique organized sport trajectories from early childhood to late adolescence in an Australian pregnancy cohort, the Raine Study. METHODS:Participation in organized sport was assessed at ages 5, 8, 10, 14, and 17 yr. Physical activity, body composition, and self-ra...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000894
更新日期:2016-07-01 00:00:00
abstract::Anthropometric and demographic characteristics are important determinants of exercise performance in healthy subjects, but their influence has not yet been studied in severe chronic heart failure, although peak oxygen uptake is frequently assessed in such patients for prognostic purposes. The aim of the present analys...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199706000-00002
更新日期:1997-06-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000631
更新日期:2015-10-01 00:00:00
abstract::The effect of glucose polymer (GP) ingestion upon endurance performance during walking exercise at 45% VO2max was examined. Also, performance on a battery of psychomotor tests was assessed to determine if exhaustion from endurance exercise was related to central nervous system dysfunction. Ten trained male subjects in...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00