Abstract：
PURPOSE:Regular physical activity leads to a more favorable cardiovascular risk factor profile and a lower risk of developing incident coronary heart disease (CHD). These correlations suggest that higher levels of physical activity should also attenuate the presence and extent of coronary atherosclerosis. METHODS:Physical activity was measured using the Baecke Physical Activity Index in 630 consecutive asymptomatic men and women ages 39-45 without known heart disease. The degree of physical activity was compared with the cardiovascular risk factor profile and the presence and extent of subclinical atherosclerosis measured using electron beam computed tomography. RESULTS:Sports-related physical activity was associated with lower body mass index (r = -0.11; P = 0.001), higher high-density lipoprotein (HDL) cholesterol (r = 0.13; P = 0.003) and less glucose resistance as assessed by fasting serum insulin levels (r = -0.16; P = 0.001). Leisure-time and work-related physical activity were unrelated to any coronary risk variables. Calcified subclinical atherosclerosis was unrelated to all physical activity dimensions. Comparing the most sedentary (lowest quartile) and most active (highest quartile) patients, the prevalence of coronary calcium (17.0% vs 18.5%; P = 0.92) and mean coronary calcium scores (8 +/- 31 vs 5 +/- 15; P = 0.87) were similar. In a multivariate model controlling for standard cardiovascular risk factors and physical activity level, only low-density lipoprotein (LDL) cholesterol was associated with the presence of coronary calcium. CONCLUSION:Physical activity, particularly high-intensity exercise in sports-related activities, promotes a healthy cardiovascular risk profile, including lower body mass index and insulin resistance, but is unrelated to coronary calcification. This suggests that the risk reduction associated with physical activity is mediated by factors other than retarding the development of calcified atherosclerosis.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Taylor AJ,Watkins T,Bell D,Carrow J,Bindeman J,Scherr D,Feuerstein I,Wong H,Bhattarai S,Vaitkus M,O'Malley PGdoi
10.1097/00005768-200202000-00008subject
Has Abstractpub_date
2002-02-01 00:00:00pages
228-33issue
2eissn
0195-9131issn
1530-0315journal_volume
34pub_type
杂志文章abstract：:The ventilatory threshold (VT) has been suggested as a method for determining exercise training intensity in cardiac transplant patients (CTPs). Since the VT has not been validated against the more accepted marker of the anaerobic threshold, the lactate threshold (LT), in CTPs, the purpose of this investigation was to...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章
doi：
更新日期：1993-02-01 00:00:00
abstract：:Ten eumenorrheic nonathletic women, aged 21-25, were studied on the 8th day following the LH peak in three consecutive cycles. Plasma level and metabolic clearance rate (MCR) of estradiol (E2) and progesterone (P) were measured before and during a 2-h continuous treadmill test at a speed corresponding to 70% of their ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：:Twelve 9- to 12-year-old children (6 boys, 6 girls) performed four exercise-in-heat (35 degrees C, 45% RH) trials which differed in the composition of the fluids they drank. In each trial, subjects cycled for one 20-min and two 15-min bouts at 50% peak VO2 with 10-min rest periods in between. In a fourth bout, they cy...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章
doi：
更新日期：1995-06-01 00:00:00
abstract：INTRODUCTION:Physical activity may affect health via DNA methylation. The epigenetic influences of sedentary behaviors such as television viewing are unknown. We performed a genomewide study of DNA methylation in peripheral blood in relation to physical activity and television viewing time. METHODS:DNA methylation was...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000001827
更新日期：2019-03-01 00:00:00
abstract：:This 1 year study examined the effect of high impact and low impact activities on bone mineral density (BMD) at the lumbar vertebrae (L2-L4) in healthy, sedentary, early postmenopausal women. Fifteen subjects whose postmenopausal status was verified by the blood levels of follicle stimulating hormone (FSH) and estradi...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1992-11-01 00:00:00
abstract：INTRODUCTION:The vascular endothelium plays an important role in the maintenance of vascular health and the modulation of vascular tone and blood pressure. Recently, it has been demonstrated that blood pressure reactivity to physical activity is greater in the morning, and possibly, diurnal variation in vascular functi...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e318195109c
更新日期：2009-06-01 00:00:00
abstract：:To compare the physiological response to a cocaine-exercise challenge in cocaine-conditioned animals with that of acute-cocaine animals, rats were injected i.p. with either cocaine (20 mg.kg-1) or saline, twice daily for 14 consecutive days. On the 15th day (test day) cocaine-conditioned rats received an i.v. injectio...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：PURPOSE:To compare the physiological and performance adaptations between periodized and nonperiodized resistance training in women collegiate tennis athletes. METHODS:Thirty women (19 +/- 1 yr) were assigned to either a periodized resistance training group (P), nonperiodized training group (NV), or a control group (C)...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章
doi：10.1097/00005768-200301000-00024
更新日期：2003-01-01 00:00:00
abstract：PURPOSE:To assess physical activity, and its associations with health, clinical, and biochemical factors, in patients with stages 2-4 of chronic kidney disease (CKD). METHODS:Cross-sectional data were collected from 120 patients with CKD enrolled in the Lipid lowering and Onset of Renal Disease (LORD) trial. Patients ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181940aef
更新日期：2009-05-01 00:00:00
abstract：:We develop an observation system that quantifies the duration, intensity, and frequency of children's physical activities. We use this system to assess the level and tempo of energy expenditure under free-ranging, natural conditions experienced by 15 children aged 6-10 yr in southern California. Observations were reco...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/00005768-199507000-00012
更新日期：1995-07-01 00:00:00
abstract：:Two swims (1993 and 1994) are described which led to post-swim orthostatic intolerance and one episode of syncope in a 50/51-yr-old well-trained and experienced marathon swimmer. The swims of 33 km and 38 km took 12 h 30 s and 17 h 35 min, respectively. Water temperature in each swim was above 23 degrees C and rectal ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1995-09-01 00:00:00
abstract：:In this study the gross efficiency of swimming was determined in a group of male (N = 6) and female (N = 4) competitive swimmers. The gross efficiency is defined as the ratio of the power output (W) to the power input (W). In a range of swimming velocities (0.95-1.6 m.s-1), the power input (rate of energy expenditure,...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
abstract：UNLABELLED:Physically active classroom lessons have been found to increase on-task behavior in children. Given that physical activity has been associated with an increased time on task (TOT) and that overweight children take fewer steps than normal weight children do, it was expected that benefits of the physical activ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181a61495
更新日期：2009-10-01 00:00:00
abstract：INTRODUCTION:Cardiac magnetic resonance (CMR) late gadolinium enhancement (LGE) and T1 mapping techniques enable the quantification of focal and diffuse myocardial LGE, respectively. Studies have shown evidence of fibrosis in middle-age athletes, but not relative to physically active (PA) adults who perform recommended...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002411
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:Water polo is a sport involving extremely intense exercise training that might be expected to result in major cardiac adaptations. The purpose of our study was to evaluate cardiac size, determine VO(2max) of top-level water polo players, and compare the findings with those of other top-level athletes. METHODS:...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.mss.0000152805.34215.97
更新日期：2005-02-01 00:00:00
abstract：PURPOSE:Stroke volume response to exercise depends on changes in cardiac filling, intrinsic myocardial contractility, and left ventricular afterload. The purpose of this study was to compare these responses during an upright cycle test performed until exhaustion in children and adults. METHODS:Stroke volume, cardiac o...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200203000-00012
更新日期：2002-03-01 00:00:00
abstract：BACKGROUND:Extracellular vesicles (EV) are purported to mediate type 2 diabetes and CVD risk and development. Physical activity and a balanced diet reduce disease risk, but no study has tested the hypothesis that short-term interval (INT) training would reduce EV compared with continuous (CONT) exercise in adults with ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002185
更新日期：2020-03-01 00:00:00
abstract：PURPOSE:The objectives of the present study were to examine gender differences and between-day variability of isometric hamstring muscle peak torque and perceived exertion. METHODS:Subjects included 20 healthy, college-aged male (N = 10) and female (N = 10) volunteers. Each subject completed five maximal voluntary iso...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1249/01.MSS.0000089246.90005.47
更新日期：2003-10-01 00:00:00
abstract：PURPOSE:Physical activity questionnaires (PAQs) are considered the most cost-efficient method to estimate total energy expenditure (TEE) in epidemiological studies. However, relatively few PAQs have been validated using doubly labeled water (DLW) in women or in samples with diverse ethnic backgrounds. This study was co...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章
doi：10.1097/00005768-200111000-00024
更新日期：2001-11-01 00:00:00
abstract：PURPOSE:The purpose of this study was to evaluate physical performance (static and dynamic) of U.S. Air Force reservists after an eastbound air travel across seven time zones and to estimate the pharmacological aids slow-release caffeine and melatonin versus placebo in attempt to overcome the decline in performance. M...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00005768-200104000-00018
更新日期：2001-04-01 00:00:00
abstract：INTRODUCTION:Oral beta2-agonist administration improves muscle function in persons without asthma. We performed a double-blind, randomized, controlled crossover study to assess whether acute inhaled salbutamol administration improves muscle strength and fatigability in healthy moderately trained subjects. METHODS:Quad...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0b013e31816b87aa
更新日期：2008-07-01 00:00:00
abstract：PURPOSE:The purpose of this study was to investigate the vibrotactile detection thresholds of the plantar cutaneous afferents in subjects with chronic ankle instability compared with healthy control subjects. METHODS:Eight adults with chronic ankle instability and eight adults with no ankle sprain history participated...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3182390212
更新日期：2012-04-01 00:00:00
abstract：PURPOSE:Previous studies have suggested that extreme endurance exercise may induce cardiac microdamage that could lead to subsequent myocardial fibrosis. Soluble suppression of tumorigenicity 2 (sST2) is a cardiac biomarker for assessment of myocardial fibrosis, inflammation, and strain. We evaluated baseline and exerc...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000001806
更新日期：2019-03-01 00:00:00
abstract：:Hydrostatic weighing (HW) was performed at residual volume (RV) and total lung capacity without head submersion (TLCNS). Ninety-five males (25.6 +/- 4.9 yr) and 87 females (22.6 +/- 5.2 yr) were studied at two laboratory sites using identical protocols. Twenty males and 20 females were separated from the original grou...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1249/00005768-198802000-00010
更新日期：1988-02-01 00:00:00
abstract：PURPOSE:Heart rate (HR) is widely used to adjust exercise intensity in aerobic training. Training HR recommendations are calculated often from simple equations. Because at lactate steady state (LASS) may be an intensity of exercise eliciting similar objective measures of intensity and similar subjective measures of met...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200205000-00024
更新日期：2002-05-01 00:00:00
abstract：PURPOSE:This study aimed to examine the influence of sagittal plane trunk posture on lower extremity energetics during running. METHODS:Forty asymptomatic recreational runners (20 males and 20 females) ran overground at a speed of 3.4 m·s(-1). Sagittal plane trunk kinematics and lower extremity kinematics and energeti...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000000436
更新日期：2015-03-01 00:00:00
abstract：PURPOSE:It is unclear how muscle strength in tibial rotation and knee abduction change following anterior cruciate ligament (ACL) injury and reconstruction. Such strength changes are likely, considering the oblique orientation of the ACL and the constraint provided by the ACL at various tibial rotation and adduction po...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章
doi：10.1097/00005768-200201000-00002
更新日期：2002-01-01 00:00:00
abstract：INTRODUCTION:Although both humans and quadrupeds frequently coordinate breathing and limb movement during running, early studies in humans focused on how increased breathing flexibility in humans allowed for relaxed or even transient coordination during locomotion. This difference was used to explain why quadrupeds had...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e318248d907
更新日期：2012-07-01 00:00:00
abstract：PURPOSE:We examined the effect of regular physical activity on plasma ghrelin concentration after onset of puberty in girls. In addition, we also examined the association of fasting plasma ghrelin concentration with various plasma biochemical, body composition, and aerobic capacity variables in healthy adolescent girls...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/mss.0b013e31812e5294
更新日期：2007-10-01 00:00:00
abstract：:The purpose of this study was to determine whether the magnitude of the activation force, defined as the force that must be applied to the load cell in order to activate the resistance arm of an isokinetic dynamometer, affected knee extensor torques. Twenty-four healthy female subjects performed resisted knee extensio...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1991-02-01 00:00:00
