Abstract:
:To compare the physiological response to a cocaine-exercise challenge in cocaine-conditioned animals with that of acute-cocaine animals, rats were injected i.p. with either cocaine (20 mg.kg-1) or saline, twice daily for 14 consecutive days. On the 15th day (test day) cocaine-conditioned rats received an i.v. injection of cocaine (5 mg.kg-1) (chronic group). One-half of the chronic saline rats also received the cocaine injection (acute group), while the other half received saline (saline group). Immediately after injection, all rats were either rested or exercised (22 m.min-1, 10% grade) for 30 min. For most parameters there was no difference between the responses of the chronic and acute cocaine groups at rest or to the cocaine-exercise challenge. During exercise, both cocaine groups had similarly higher lactate values than the saline animals (P < 0.05). Both groups had similarly greater reductions in glycogen content of the white and red vastus muscles than occurred in the saline group; and both groups had similar increases in corticosterone. In contrast, cocaine-conditioned animals had a greater rise in norepinephrine (P < 0.059) and epinephrine (P < 0.001) in response to cocaine-exercise than did the acute group. The mechanism responsible for the exaggerated catecholamine response in the chronic cocaine animals is unknown.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Kelly KP,Han DH,Fellingham GW,Winder WW,Conlee RKsubject
Has Abstractpub_date
1995-01-01 00:00:00pages
65-72issue
1eissn
0195-9131issn
1530-0315journal_volume
27pub_type
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journal_title:Medicine and science in sports and exercise
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journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
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journal_title:Medicine and science in sports and exercise
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journal_title:Medicine and science in sports and exercise
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更新日期:1981-01-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:10.1097/00005768-199712000-00006
更新日期:1997-12-01 00:00:00
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journal_title:Medicine and science in sports and exercise
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doi:10.1097/00005768-200103000-00025
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更新日期:2005-11-01 00:00:00
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journal_title:Medicine and science in sports and exercise
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更新日期:2005-05-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1984-12-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:10.1097/00005768-200007001-00008
更新日期:2000-07-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1990-04-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
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更新日期:2019-04-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
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journal_title:Medicine and science in sports and exercise
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199801000-00024
更新日期:1998-01-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
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更新日期:2001-11-01 00:00:00
abstract:INTRODUCTION:Despite the widespread utilization of the Balance Error Scoring System (BESS) in the evaluation of concussion, it has been criticized for its error-based scoring that is susceptible to floor and ceiling effects and substantial inter-rater variability. A biomechanical outcome, Cleveland Clinic Postural Stab...
journal_title:Medicine and science in sports and exercise
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更新日期:2018-10-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200205000-00024
更新日期:2002-05-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199802000-00009
更新日期:1998-02-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
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更新日期:2016-01-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
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更新日期:2012-12-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001692
更新日期:2018-11-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000000244
更新日期:2014-07-01 00:00:00