Abstract：
PURPOSE:This study examined whether plasma total glutathione levels could explain the intersubject variability in the creatine kinase (CK) response to eccentric exercise. We hypothesized that the increase in plasma CK activity after eccentric exercise would be lower for individuals with low plasma total glutathione (<2.5 micromol x L-1) compared with individuals with high total glutathione (>3.8 micromol x L-1), but other indicators of muscle damage would be the same between groups. METHODS:Resting blood samples were obtained over 2 d from 60 subjects and analyzed for plasma total glutathione. Eight subjects who had total glutathione values below 2.5 micromol x L-1 (LG), and nine who had values above 3.8 micromol x L-1 (HG) performed 50 maximal eccentric actions of the elbow flexors. Maximal voluntary isometric contraction (MVC), relaxed arm angle (RANG), and blood samples for CK, myoglobin (Mb), and total glutathione were obtained pre, post (except blood samples), 24, 48, 72, 96, and 120 h after exercise. RESULTS:There was a significant group-by-time interaction in analysis of MVC, RANG, total glutathione, CK, and Mb response to exercise. Although LG showed a smaller CK response to eccentric exercise compared with HG, LG also showed a smaller increase in plasma Mb, a faster recovery of MVC and RANG, and an increase in plasma total glutathione. CONCLUSION:Subjects with low plasma total glutathione levels had a smaller plasma CK and Mb response and a faster recovery from eccentric exercise compared with subjects having high plasma total glutathione levels. We suggest that a blunted inflammatory response in subjects with low plasma glutathione may be one explanation for these findings.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Lee J,Clarkson PMdoi
10.1249/01.MSS.0000069553.47739.36subject
Has Abstractpub_date
2003-06-01 00:00:00pages
930-6issue
6eissn
0195-9131issn
1530-0315journal_volume
35pub_type
杂志文章abstract：:We investigated the breath-by-breath pattern of ventilatory response to bicycle exercise in seven elite male cyclists (VO2max = 71.7 ml X min-1 X kg-1) and ten sedentary males (VO2max = 47.3 ml X min-1 X kg-1) to analyze differences in breathing patterns between individuals with normal and high exercise ventilations (...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：:It has been suggested that television watching and physical activity are related to obesity. This association, however, has been investigated mainly in children. This study provided the opportunity to examine the relationship between television watching, physical activity, and body mass index in adult Pima Indians, a ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199707000-00010
更新日期：1997-07-01 00:00:00
abstract：:It is the position of the American Dietetic Association, Dietitians of Canada, and the American College of Sports Medicine that physical activity, athletic performance, and recovery from exercise are enhanced by optimal nutrition. These organizations recommend appropriate selection of foods and fluids, timing of intak...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,实务指引,评审
doi：10.1249/MSS.0b013e31890eb86
更新日期：2009-03-01 00:00:00
abstract：PURPOSE:This study was designed to compare the differences in EMG and kinematics between successful and unsuccessful attempts in bench pressing at one repetition maximum (1RM) in recreational weight-trained subjects. We hypothesized that failure occurs during the sticking period (the period during which there is a temp...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181a8c360
更新日期：2009-11-01 00:00:00
abstract：PURPOSE:To compare the effects of different patterns of regular brisk walking on fitness, risk factors for cardiovascular disease, and psychological well-being in previously sedentary adults. METHODS:Twenty-one subjects (14 women), aged 44.5 +/- 6.1 yr (mean +/- SD) were randomly assigned to two different, 6-wk progra...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00005768-200209000-00011
更新日期：2002-09-01 00:00:00
abstract：PURPOSE:It has been well established in mammals that circadian behavior as well as the molecular clockwork can be synchronized to the light-dark cycle via the suprachiasmatic nucleus of the hypothalamus (SCN). In addition to light, it has been demonstrated that nonphotic time cues, such as restricting the time of food ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e318255cf4c
更新日期：2012-09-01 00:00:00
abstract：PURPOSE:Muscle sympathetic nerve activity (MSNA) is increased in older endurance-trained men, yet the reflex sympathetic forearm vasoconstrictor response to graded lower body negative pressure (LBNP) diminishes with age. The aim of this study was to assess the influence of aerobic exercise capacity on this altered neur...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e31822a68a5
更新日期：2012-02-01 00:00:00
abstract：PURPOSE:Compelling evidence suggests larger performance decrements during hypoxic versus normoxic repeated sprinting. Yet the underlying mechanical alterations have not been thoroughly investigated. Therefore, we examined the effects of different levels of normobaric hypoxia on running mechanical performance during rep...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0000000000000937
更新日期：2016-08-01 00:00:00
abstract：PURPOSE:Cold-water immersion (CWI) and whole body cryotherapy (WBC) are widely used recovery methods in an attempt to limit exercise-induced muscle damage, soreness, and functional deficits after strenuous exercise. The aim of this study was to compare the effects of ecologically valid CWI and WBC protocols on postexer...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0000000000001223
更新日期：2017-06-01 00:00:00
abstract：PURPOSE:This study investigated the kinetic and the kinematic differences in female athletes in single-leg static jumps in an aquatic environment compared with those performed on dry land. METHODS:Twelve healthy, junior national team handball players participated. Subjects completed a familiarization and a testing ses...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181a252b7
更新日期：2009-09-01 00:00:00
abstract：:The relationship between VO2 and velocity of running (running economy) has been rather casually dealt with until very recently, and there still remains considerable disagreement as to the importance of this variable. Various factors which have been shown, or appear, to affect running economy include environment (tempe...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：
更新日期：1985-06-01 00:00:00
abstract：PURPOSE:To evaluate the effects of intensity of exercise on insulin resistance and the expression of inflammatory proteins in the skeletal muscle of diet-induced obese (DIO) rats after a single bout of exercise. METHODS:In the first exercise protocol, the rats swam for two 3-h bouts, separated by a 45-min rest period ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181e45d08
更新日期：2010-12-01 00:00:00
abstract：PURPOSE:The purpose of this study was to identify electromyographic (EMG) differences in the latent muscle reaction timing (LMRT) of the rotator cuff between trained overhead throwers and control subjects in response to sudden internal rotation perturbation (P < or = 0.05). METHODS:Subjects included 15 trained overhea...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199910000-00006
更新日期：1999-10-01 00:00:00
abstract：INTRODUCTION/PURPOSE:Decreased lumbo-pelvic (or core) stability has been suggested to contribute to the etiology of lower extremity injuries, particularly in females. This prospective study compares core stability measures between genders and between athletes who reported an injury during their season versus those who ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.mss.0000128145.75199.c3
更新日期：2004-06-01 00:00:00
abstract：PURPOSE:The study's purpose was to examine the effects of a short-term period with intensified training or training cessation of trained soccer players on VO(2) kinetics at 75% maximal aerobic speed, oxidative enzymes, and performance in repeated high-intensity exercise. METHODS:After the last match of the season, 18 ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e318211c01a
更新日期：2011-09-01 00:00:00
abstract：INTRODUCTION:Physical endurance can be limited by muscle glycogen stores, in that glycogen depletion markedly reduces external work. During carbohydrate restriction, the liver synthesizes the ketone bodies, D-β-hydroxybutyrate, and acetoacetate from fatty acids. In animals and in the presence of glucose, D-β-hydroxybut...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0000000000001292
更新日期：2017-09-01 00:00:00
abstract：INTRODUCTION:Alternative high school (AHS) students are an underserved population of youth at greater risk for poor health behaviors and outcomes. Little is known about their physical activity patterns. PURPOSE:: The purpose of this study was to describe 1) physical activity levels of students attending alternative hi...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e318182092b
更新日期：2008-12-01 00:00:00
abstract：PURPOSE:Physical exercise or hypoxic exposure influences hemorheology and acid-base homeostasis. Band 3 protein in erythrocytes modulates cells' rheological properties and anion transport ability. This study investigated how cycling aerobic interval training (AIT) and moderate continuous training (MCT) affect the rheol...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0000000000000730
更新日期：2016-01-01 00:00:00
abstract：:This 1 year study examined the effect of high impact and low impact activities on bone mineral density (BMD) at the lumbar vertebrae (L2-L4) in healthy, sedentary, early postmenopausal women. Fifteen subjects whose postmenopausal status was verified by the blood levels of follicle stimulating hormone (FSH) and estradi...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1992-11-01 00:00:00
abstract：PURPOSE:To determine whether the magnitude of improvement in athletic performance and the mechanisms driving these adaptations differ in relatively weak individuals exposed to either ballistic power training or heavy strength training. METHODS:Relatively weak men (n = 24) who could perform the back squat with proficie...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0b013e3181d2013a
更新日期：2010-08-01 00:00:00
abstract：PURPOSE:To examine whether knowledge of the 1995 Centers for Disease Control and Prevention (CDC) and the American College of Sports Medicine (ACSM) national physical activity recommendations varies by sociodemographic, behavioral, and communication-related factors. METHODS:Cross-sectional analyses of 2381 participant...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181a52100
更新日期：2009-10-01 00:00:00
abstract：:The objective of this study was to design and validate a working tool for the objective evaluation of daily energy expenditure (DEE) by means of a simple, noninvasive method: the QAPSE (Saint-Etienne Physical Activity Questionnaire), a questionnaire about physical activity (PA) over a period of 7 d (168 h). This eight...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1993-12-01 00:00:00
abstract：PURPOSE:We evaluated the associations between accelerometer-estimated physical activity (PA) intensity and heart rate variability (HRV) and examined mediation of these associations by glycemic control indices and other cardiovascular disease risk factors. METHODS:Data were from 1668 participants (X[Combining Overline]...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002259
更新日期：2020-06-01 00:00:00
abstract：PURPOSE:This study aimed to determine the effect of cooling progressively greater portions of the lower extremities on dynamic balance and neuromuscular activation. METHODS:Ten healthy males (22.8 ± 3.4 yr, 76.5 ± 9.1 kg) performed one room air temperature control (22.4°C ± 0.8°C) and three trials of cold water immers...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000000379
更新日期：2015-01-01 00:00:00
abstract：PURPOSE:This is the first study to use the quiet eye (QE) as an objective measure of visuomotor control underpinning proficiency differences in children's motor coordination. METHODS:Fifty-seven, year 5 primary school children (9-10 yr old) completed the Movement Assessment Battery for Children, Second Edition (MABC-2...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e31828288f1
更新日期：2013-06-01 00:00:00
abstract：PURPOSE:The purpose of this study was to determine whether high frequency fatigue was present in the diaphragm after intense whole body endurance exercise. METHODS:We used bilateral phrenic nerve stimulation (BPNS) before and during recovery from whole body exercise to detect fatigue in the diaphragm. To detect high f...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199804000-00006
更新日期：1998-04-01 00:00:00
abstract：:The assumption that lower extremity function is bilaterally symmetrical is prevalent throughout the biomechanics literature. The unilateral development of many overuse and acute injuries may suggest that this assumption is inaccurate. Analyses of bilateral function report conflicting results and may be partially attri...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1994-09-01 00:00:00
abstract：PURPOSE:The Compendium of Physical Activities was developed to enhance the comparability of results across studies using self-report physical activity (PA) and is used to quantify the energy cost of a wide variety of PA. We provide the second update of the Compendium, called the 2011 Compendium. METHODS:The 2011 Compe...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e31821ece12
更新日期：2011-08-01 00:00:00
abstract：PURPOSE:This study was undertaken to determine whether endurance training is associated with changes in myocardial perfusion in humans. METHODS:Myocardial perfusion was measured in eleven trained and nine sedentary men at rest and during adenosine-stimulated hyperemia using positron emission tomography (PET). Left ven...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章
doi：10.1097/00005768-200206000-00007
更新日期：2002-06-01 00:00:00
abstract：:The coordination of blood flow control in exercising skeletal muscle is exemplified by the interaction among muscle fibers, nerves, and the smooth muscle and endothelial cells which comprise the resistance vasculature. During functional hyperemia in active muscle, maximal flow exceeds resting values by 10- to 50-fold,...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：
更新日期：1995-08-01 00:00:00
