Association between Objective Activity Intensity and Heart Rate Variability: Cardiovascular Disease Risk Factor Mediation (CARDIA).

Abstract:

PURPOSE:We evaluated the associations between accelerometer-estimated physical activity (PA) intensity and heart rate variability (HRV) and examined mediation of these associations by glycemic control indices and other cardiovascular disease risk factors. METHODS:Data were from 1668 participants (X[Combining Overline]age = 45.9 ± 3.5 yr, 58.0% female, 39.9% black) who participated in year 20 (2005-2006) of the Coronary Artery Risk Development in Young Adults Fitness Study. The ActiGraph 7164 estimated participants' mean minutes per day of vigorous-intensity PA (VPA), moderate-intensity PA (MPA), and light-intensity PA (LPA) over 7 d. Three sequential 10-s 12-lead ECG strips were used to derive standard deviation of all normal RR intervals (SDNN) and root mean square of all successive RR intervals (rMSSD) HRV. Mediators representing glycemic control indices included fasting glucose, fasting insulin, and 2-h oral glucose tolerance, with other mediators being traditional cardiovascular disease risk factors. Multiple linear regression assessed independent associations of PA intensity with HRV per 1-SD. Mediation analyses computed the proportion of the PA-HRV association attributable to physiological mediators. RESULTS:Participants averaged 2.7 ± 6.2 min·d, 33.0 ± 22.0 min·d, and 360.2 ± 83.8 min·d of VPA, MPA, and LPA, respectively, with mean values for SDNN (32.6 ± 22.4 ms) and rMSSD (34.0 ± 24.8 ms) similar. After adjustment for demographic and lifestyle behaviors, VPA was associated with both HRV metrics (SDNN: std beta = 0.06 [0.03, 0.10]; rMSSD: std beta = 0.08 [0.05, 0.12]) and LPA with rMSSD only (std beta = 0.05 [0.01, 0.08]). Fasting insulin and glucose mediated 11.6% to 20.7% of the association of VPA and LPA with HRV, with triglycerides also potentially mediating these associations (range, 9.6%-13.4%). CONCLUSIONS:Accelerometer-estimated VPA was associated with higher (i.e., improved) HRV. Light-intensity PA also demonstrated a positive association. Mediation analyses suggested these associations may be most attributable to glucose-insulin dynamics.

journal_name

Med Sci Sports Exerc

authors

Pope ZC,Gabriel KP,Whitaker KM,Chen LY,Schreiner PJ,Jacobs DR Jr,Sternfeld B,Carr JJ,Lloyd-Jones DM,Pereira MA

doi

10.1249/MSS.0000000000002259

subject

Has Abstract

pub_date

2020-06-01 00:00:00

pages

1314-1321

issue

6

eissn

0195-9131

issn

1530-0315

pii

00005768-202006000-00009

journal_volume

52

pub_type

杂志文章
  • Cleveland Clinic Postural Stability Index Norms for the Balance Error Scoring System.

    abstract:INTRODUCTION:Despite the widespread utilization of the Balance Error Scoring System (BESS) in the evaluation of concussion, it has been criticized for its error-based scoring that is susceptible to floor and ceiling effects and substantial inter-rater variability. A biomechanical outcome, Cleveland Clinic Postural Stab...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000001660

    authors: Linder SM,Ozinga SJ,Koop MM,Dey T,Figler R,Cruickshank J,Alberts JL

    更新日期:2018-10-01 00:00:00

  • Metabolic determinants of 1-mile run/walk performance in children.

    abstract::The 1-mile run/walk test is the field test of choice for evaluating maximal aerobic power (VO2max) in school-aged children. The objective of this study was to determine the relative importance of selected metabolic determinants of mile run/walk performance in children 6-14 yr of age. Mile run/walk time (MRWT), VO2max,...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:

    authors: McCormack WP,Cureton KJ,Bullock TA,Weyand PG

    更新日期:1991-05-01 00:00:00

  • Distal radio-ulnar joint dislocation, ulna volar in a female body builder.

    abstract::A 23-yr-old female body builder injured her right wrist while training. A correct diagnosis of pure distal radio-ulnar dislocation, ulnar volar, was made, and reduction was successfully carried out. After removal of plaster, the patient complained of wrist pain and clicking. Surgical exploration revealed a ruptured tr...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:

    authors: Francobandiera C,Maffulli N,Lepore L

    更新日期:1990-04-01 00:00:00

  • A study of exercise modality and physical self-esteem in breast cancer survivors.

    abstract:PURPOSE:This study, theoretically based on the Exercise Self-Esteem Model, EXSEM, examined effects of exercise modality on physical and global self-esteem (PSE, GSE) in breast cancer survivors. The EXSEM posits GSE at the apex with PSE feeding into GSE. PSE has three subdomains: physical condition (PC), attractive body...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章,随机对照试验

    doi:10.1249/MSS.0b013e31822cb5f2

    authors: Musanti R

    更新日期:2012-02-01 00:00:00

  • Ankle Proprioception-Associated Gait Patterns in Older Adults: Results from the Baltimore Longitudinal Study of Aging.

    abstract:INTRODUCTION:Ankle proprioception training has been found to improve balance-related gait disorders; however, the relationship between ankle proprioception and specific gait patterns in older adults with and without impaired balance has not been systematically examined. METHODS:This study characterizes gait patterns o...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000001017

    authors: Ko SU,Simonsick EM,Deshpande N,Studenski S,Ferrucci L

    更新日期:2016-11-01 00:00:00

  • Metabolic actions of estradiol: significance for acute and chronic exercise responses.

    abstract::Although estradiol (E2) is considered primarily for its role in reproduction, it can exert numerous physiological actions on a variety of tissues. However, there are several difficulties in isolating these actions and determining its impact for in vivo situations. Despite the limitations, it does appear that E2 can al...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章,评审

    doi:

    authors: Bunt JC

    更新日期:1990-06-01 00:00:00

  • Relationship between sex hormones and anterior knee laxity across the menstrual cycle.

    abstract:PURPOSE:To comprehensively quantify through daily, serial measures changes in knee laxity as a function of changing sex-hormone levels across one complete menstrual cycle. METHODS:Twenty-five females, 18 - 30 yr, body mass index < or = 30, who reported normal menstrual cycles (28-32 d) over the past 6 months participa...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/01.mss.0000132270.43579.1a

    authors: Shultz SJ,Kirk SE,Johnson ML,Sander TC,Perrin DH

    更新日期:2004-07-01 00:00:00

  • Microvascular Dilator Function in Athletes: A Systematic Review and Meta-analysis.

    abstract:PURPOSE:Despite the growing research interest in vascular adaptations to exercise training over the last few decades, it remains unclear whether microvascular function in healthy subjects can be further improved by regular training. Herein, we sought to systematically review the literature and determine whether microva...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章,meta分析,评审

    doi:10.1249/MSS.0000000000000567

    authors: Montero D,Walther G,Diaz-Cañestro C,Pyke KE,Padilla J

    更新日期:2015-07-01 00:00:00

  • Physical Activity, Cardiorespiratory Fitness, and Incident Glaucoma.

    abstract:PURPOSE:This study aimed to examine the associations of physical activity and cardiorespiratory fitness (hereafter fitness) with incident glaucoma in a prospective observational study. METHODS:Physical activity was measured by self-reported leisure-time activities, and fitness was measured by maximal treadmill test. I...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000001692

    authors: Meier NF,Lee DC,Sui X,Blair SN

    更新日期:2018-11-01 00:00:00

  • Coingestion of Carbohydrate and Protein on Muscle Glycogen Synthesis after Exercise: A Meta-analysis.

    abstract:INTRODUCTION/PURPOSE:Evidence suggests that carbohydrate and protein (CHO-PRO) ingestion after exercise enhances muscle glycogen repletion to a greater extent than carbohydrate (CHO) alone. However, there is no consensus at this point, and results across studies are mixed, which may be attributable to differences in en...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000002476

    authors: Margolis LM,Allen JT,Hatch-McChesney A,Pasiakos SM

    更新日期:2021-02-01 00:00:00

  • Stretch-activated ion channel blockade attenuates adaptations to eccentric exercise.

    abstract:PURPOSE:The purpose of this study was to test the hypothesis that stretch-activated ion channel (SAC) function is essential for the repeated bout effect (RBE) in skeletal muscle. Specifically, we investigated if daily injections of streptomycin (a known SAC blocker) would abrogate the muscle's adaptive resistance to th...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0b013e318187cffa

    authors: Butterfield TA,Best TM

    更新日期:2009-02-01 00:00:00

  • Vertical and radial motions of the body during the take-off phase of high jumping.

    abstract::By placing the muscles of the take-off leg in faster eccentric or slower concentric conditions, a high jumper can increase the ground reaction force and the height of the jump. Film analysis of seven high jumpers showed that the radial velocity of the center of mass with respect to the supporting foot was more negativ...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/00005768-198806000-00014

    authors: Dapena J,Chung CS

    更新日期:1988-06-01 00:00:00

  • Respiratory muscle fatigue during exercise: implications for performance.

    abstract::Heavy whole-body exercise, requiring a 10- to 15-fold increase in minute ventilation, encroaches on the capacities of the respiratory muscle system to respond. Recently, using the technique of bilateral phrenic nerve stimulation, it has been shown that heavy endurance exercise (> 85% of VO2max) lasting > 8-10 min caus...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章,评审

    doi:10.1097/00005768-199609000-00008

    authors: Johnson BD,Aaron EA,Babcock MA,Dempsey JA

    更新日期:1996-09-01 00:00:00

  • Association between the GNB3 polymorphism and blood pressure in young Korean men.

    abstract:PURPOSE:The purpose of the current study was to investigate the associations between the GNB3 C825T polymorphism, body fatness and fitness, and blood pressure in a sample of young Korean men. METHODS:A total of 282 apparently healthy Korean men (nonobese N = 152, obese N = 130) aged 19-33 yr participated in the study....

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/01.mss.0000170096.96662.05

    authors: Lee J,Lee S,Shin S,Kang HS

    更新日期:2005-07-01 00:00:00

  • Hip Strength in Patients with Quadriceps Strength Deficits after ACL Reconstruction.

    abstract:PURPOSE:Quadriceps strength deficits persist for years after anterior cruciate ligament (ACL) reconstruction, and patients with these deficits often shift torque demands away from the knee extensors to the hip during functional tasks. However, it is not clear how quadriceps strength deficits may affect hip strength. Th...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000000999

    authors: Bell DR,Trigsted SM,Post EG,Walden CE

    更新日期:2016-10-01 00:00:00

  • Ventilatory response to exercise in simulated obesity by chest loading.

    abstract:INTRODUCTION & PURPOSE:Obesity-related increases of weight on the chest wall are known to decrease lung volume and chest wall compliance, but the effect of this mass loading, independent of other obesity-related complications on the ventilatory response to exercise is unknown. The purpose of this study was to investiga...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/01.mss.0000126386.12402.f5

    authors: Wang LY,Cerny FJ

    更新日期:2004-05-01 00:00:00

  • Exercise performance over the menstrual cycle in temperate and hot, humid conditions.

    abstract:PURPOSE:This study investigated the effects of the menstrual cycle on prolonged exercise performance both in temperate (20°C, 45% relative humidity) and hot, humid (32°C, 60% relative humidity) conditions. METHODS:For each environmental condition, 12 recreationally active females were tested during the early follicula...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0b013e3182656f13

    authors: Janse DE Jonge XA,Thompson MW,Chuter VH,Silk LN,Thom JM

    更新日期:2012-11-01 00:00:00

  • Bilateral performance symmetry during drop landing: a kinetic analysis.

    abstract::The assumption that lower extremity function is bilaterally symmetrical is prevalent throughout the biomechanics literature. The unilateral development of many overuse and acute injuries may suggest that this assumption is inaccurate. Analyses of bilateral function report conflicting results and may be partially attri...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:

    authors: Schot PK,Bates BT,Dufek JS

    更新日期:1994-09-01 00:00:00

  • Physical conditioning attenuates respiratory responses to steady-state exercise in late gestation.

    abstract:PURPOSE:To study the ventilatory effects of closely monitored cycle ergometer conditioning (HR target, 145-150 beats x min(-1); 25 min/session; three sessions per week) during the second and third pregnancy trimesters (TMs) in healthy human pregnancy. METHODS:Subjects were 27 previously sedentary pregnant women (exerc...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1097/00005768-199801000-00004

    authors: Ohtake PJ,Wolfe LA

    更新日期:1998-01-01 00:00:00

  • Validity of the Actical accelerometer step-count function.

    abstract:PURPOSE:To assess the validity of the new Actical accelerometer step count function. METHODS:Actical step counts were compared according to two criterion standards. 1) Eight Acticals were assessed using a mechanical shaker table under six different testing conditions. 2) Thirty-eight volunteers (aged 9-59 yr) wore eig...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/mss.0b013e3804ec4e9

    authors: Esliger DW,Probert A,Connor Gorber S,Bryan S,Laviolette M,Tremblay MS

    更新日期:2007-07-01 00:00:00

  • Effect of pyruvate and dihydroxyacetone on metabolism and aerobic endurance capacity.

    abstract::Pyruvate and dihydroxyacetone are three carbon compounds that when infused directly into the blood or taken orally produce strong metabolic effects. When chronically fed to animals as part of their diet, pyruvate plus dihydroxyacetone reduce the rate of weight gain and body fat content during growth. These alterations...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章,评审

    doi:10.1097/00005768-199806000-00010

    authors: Ivy JL

    更新日期:1998-06-01 00:00:00

  • Applying the ACSM Preparticipation Screening Algorithm to U.S. Adults: National Health and Nutrition Examination Survey 2001-2004.

    abstract:PURPOSE:For most people, the benefits of physical activity far outweigh the risks. Research has suggested that exercise preparticipation questionnaires might refer an unwarranted number of adults for medical evaluation before exercise initiation, creating a potential barrier to adoption. The new American College of Spo...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000001331

    authors: Whitfield GP,Riebe D,Magal M,Liguori G

    更新日期:2017-10-01 00:00:00

  • Effect of intense training on plasma leptin in male and female swimmers.

    abstract:PURPOSE:The purpose of this study was to determine whether fasting plasma leptin concentration was altered with an increase in training volume in competitive male and female athletes. METHODS:Intercollegiate male (N = 9) and female (N = 12) swimmers were examined during the preseason and at two times during the mid-se...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1097/00005768-200102000-00009

    authors: Noland RC,Baker JT,Boudreau SR,Kobe RW,Tanner CJ,Hickner RC,McCammon MR,Houmard JA

    更新日期:2001-02-01 00:00:00

  • The influence of body mass in endurance bicycling.

    abstract::Bicycling is a complex sport in which an athlete's energy cost is related to two principal forces: air resistance when traveling on flat terrain, and gravity when traveling uphill. Both wind tunnel data and physiological measurements suggest that air resistance scales as body mass to about the 1/3 power. Thus, large c...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章,评审

    doi:

    authors: Swain DP

    更新日期:1994-01-01 00:00:00

  • Menstrual function and eating behavior in female recreational weight lifters and competitive body builders.

    abstract::A group of 103 female weight lifters (WL) and 92 control (C) women answered a survey concerning eating behavior and attitudes (including the Eating Disorder Inventory) and menstrual function. The incidence of menstrual dysfunction, defined as oligomenorrhea plus amenorrhea, was significantly higher for the WL (30%) th...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:

    authors: Walberg JL,Johnston CS

    更新日期:1991-01-01 00:00:00

  • Heart rate variability during recovery from a Wingate test in adolescent males.

    abstract:PURPOSE:To evaluate the effect of maturity status on the autonomic nervous system at rest and recovery after short-term, high-intensity exercise in adolescents. METHODS:A biological maturity age was estimated in 27 males by calculating the years from peak height velocity (PHV) using a multiple regression equation. Sub...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/01.mss.0000218126.46242.2e

    authors: Goulopoulou S,Heffernan KS,Fernhall B,Yates G,Baxter-Jones AD,Unnithan VB

    更新日期:2006-05-01 00:00:00

  • Exercise and the incidence of upper respiratory tract infections.

    abstract::We examined illness patterns in a cohort of 530 male and female runners who completed a monthly log for 12 months. The average number of upper respiratory tract infections (URTIs) per person per year for the cohort was 1.2. An upper respiratory tract infection was indicated by the report of any of the following sympto...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:

    authors: Heath GW,Ford ES,Craven TE,Macera CA,Jackson KL,Pate RR

    更新日期:1991-02-01 00:00:00

  • Comparison of the ActiGraph 7164 and the ActiGraph GT1M during self-paced locomotion.

    abstract:PURPOSE:This study compared the ActiGraph accelerometer model 7164 (AM1) with the ActiGraph GT1M (AM2) during self-paced locomotion. METHODS:Participants (n = 116, aged 18-73 yr, mean body mass index = 26.1 kg x m(-2)) walked at self-selected slow, medium, and fast speeds around an indoor circular hallway (0.47 km). B...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0b013e3181c29e90

    authors: Kozey SL,Staudenmayer JW,Troiano RP,Freedson PS

    更新日期:2010-05-01 00:00:00

  • Development and characterization of an overtraining animal model.

    abstract:PURPOSE:Development of an endurance training-overtraining protocol for Wistar rats that includes increased workload and is characterized by analyses of performance and biomarkers. METHODS:The running protocol lasted 11 wk: 8 wk of daily exercise sessions followed by 3 wk of increasing training frequency (two, three, a...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0b013e318191259c

    authors: Hohl R,Ferraresso RL,De Oliveira RB,Lucco R,Brenzikofer R,De Macedo DV

    更新日期:2009-05-01 00:00:00

  • Scheduled exercise phase shifts the circadian clock in skeletal muscle.

    abstract:PURPOSE:It has been well established in mammals that circadian behavior as well as the molecular clockwork can be synchronized to the light-dark cycle via the suprachiasmatic nucleus of the hypothalamus (SCN). In addition to light, it has been demonstrated that nonphotic time cues, such as restricting the time of food ...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0b013e318255cf4c

    authors: Wolff G,Esser KA

    更新日期:2012-09-01 00:00:00