Coingestion of Carbohydrate and Protein on Muscle Glycogen Synthesis after Exercise: A Meta-analysis.

Abstract:

INTRODUCTION/PURPOSE:Evidence suggests that carbohydrate and protein (CHO-PRO) ingestion after exercise enhances muscle glycogen repletion to a greater extent than carbohydrate (CHO) alone. However, there is no consensus at this point, and results across studies are mixed, which may be attributable to differences in energy content and carbohydrate intake relative to body mass consumed after exercise. The purpose of this study was determine the overall effects of CHO-PRO and the independent effects of energy and relative carbohydrate content of CHO-PRO supplementation on postexercise muscle glycogen synthesis compared with CHO alone. METHODS:Meta-analysis was conducted on crossover studies assessing the influence of CHO-PRO compared with CHO alone on postexercise muscle glycogen synthesis. Studies were identified in a systematic review from PubMed and Cochrane Library databases. Data are presented as effect size (95% confidence interval [CI]) using Hedges' g. Subgroup analyses were conducted to evaluate effects of isocaloric and nonisocaloric energy content and dichotomized by median relative carbohydrate (high, ≥0.8 g·kg-1⋅h-1; low, <0.8 g·kg-1⋅h-1) content on glycogen synthesis. RESULTS:Twenty studies were included in the analysis. CHO-PRO had no overall effect on glycogen synthesis (0.13, 95% CI = -0.04 to 0.29) compared with CHO. Subgroup analysis found that CHO-PRO had a positive effect (0.26, 95% CI = 0.04-0.49) on glycogen synthesis when the combined intervention provided more energy than CHO. Glycogen synthesis was not significant (-0.05, 95% CI = -0.23 to 0.13) in CHO-PRO compared with CON when matched for energy content. There was no statistical difference of CHO-PRO on glycogen synthesis in high (0.07, 95% CI = -0.11 to 0.22) or low (0.21, 95% CI = -0.08 to 0.50) carbohydrate content compared with CHO. CONCLUSION:Glycogen synthesis rates are enhanced when CHO-PRO are coingested after exercise compared with CHO only when the added energy of protein is consumed in addition to, not in place of, carbohydrate.

journal_name

Med Sci Sports Exerc

authors

Margolis LM,Allen JT,Hatch-McChesney A,Pasiakos SM

doi

10.1249/MSS.0000000000002476

subject

Has Abstract

pub_date

2021-02-01 00:00:00

pages

384-393

issue

2

eissn

0195-9131

issn

1530-0315

pii

00005768-202102000-00016

journal_volume

53

pub_type

杂志文章
  • Assessing sedentary behavior with the GENEActiv: introducing the sedentary sphere.

    abstract:BACKGROUND:The Sedentary Sphere is a method for the analysis, identification, and visual presentation of sedentary behaviors from a wrist-worn triaxial accelerometer. PURPOSE:This study aimed to introduce the concept of the Sedentary Sphere and to determine the accuracy of posture classification from wrist acceleromet...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000000224

    authors: Rowlands AV,Olds TS,Hillsdon M,Pulsford R,Hurst TL,Eston RG,Gomersall SR,Johnston K,Langford J

    更新日期:2014-06-01 00:00:00

  • Life Events and Longitudinal Effects on Physical Activity: Adolescence to Adulthood.

    abstract:INTRODUCTION:Common life events, such as getting married or gaining employment, may be opportunities to intervene on health behaviors like physical activity. The purpose of this study was to determine the changes in moderate-to-vigorous physical activity (MVPA) associated with several common life events from adolescenc...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000001839

    authors: Miller J,Nelson T,Barr-Anderson DJ,Christoph MJ,Winkler M,Neumark-Sztainer D

    更新日期:2019-04-01 00:00:00

  • Relationship between sex hormones and anterior knee laxity across the menstrual cycle.

    abstract:PURPOSE:To comprehensively quantify through daily, serial measures changes in knee laxity as a function of changing sex-hormone levels across one complete menstrual cycle. METHODS:Twenty-five females, 18 - 30 yr, body mass index < or = 30, who reported normal menstrual cycles (28-32 d) over the past 6 months participa...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/01.mss.0000132270.43579.1a

    authors: Shultz SJ,Kirk SE,Johnson ML,Sander TC,Perrin DH

    更新日期:2004-07-01 00:00:00

  • Evaluation of stroke performance in tennis.

    abstract::In the present studies, the Leuven Tennis Performance Test (LTPT), a newly developed test procedure to measure stroke performance in match-like conditions in elite tennis players, was evaluated as to its value for research purposes. The LTPT is enacted on a regular tennis court. It consists of first and second service...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1097/00005768-199808000-00016

    authors: Vergauwen L,Spaepen AJ,Lefevre J,Hespel P

    更新日期:1998-08-01 00:00:00

  • Running Exercise in Obese Pregnancies Prevents IL-6 Trans-signaling in Male Offspring.

    abstract:PURPOSE:Maternal obesity is known to predispose the offspring to impaired glucose metabolism and obesity associated with low-grade inflammation and hypothalamic dysfunction. Because preventive approaches in this context are missing to date, we aimed to identify molecular mechanisms in the offspring that are affected by...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000000835

    authors: Bae-Gartz I,Janoschek R,Kloppe CS,Vohlen C,Roels F,Oberthür A,Alejandre Alcazar MA,Lippach G,Muether PS,Dinger K,Ferrari N,Graf C,Dötsch J,Hucklenbruch-Rother E

    更新日期:2016-05-01 00:00:00

  • Stretch-activated ion channel blockade attenuates adaptations to eccentric exercise.

    abstract:PURPOSE:The purpose of this study was to test the hypothesis that stretch-activated ion channel (SAC) function is essential for the repeated bout effect (RBE) in skeletal muscle. Specifically, we investigated if daily injections of streptomycin (a known SAC blocker) would abrogate the muscle's adaptive resistance to th...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0b013e318187cffa

    authors: Butterfield TA,Best TM

    更新日期:2009-02-01 00:00:00

  • The mechanical efficiency of front crawl swimming.

    abstract::In this study the gross efficiency of swimming was determined in a group of male (N = 6) and female (N = 4) competitive swimmers. The gross efficiency is defined as the ratio of the power output (W) to the power input (W). In a range of swimming velocities (0.95-1.6 m.s-1), the power input (rate of energy expenditure,...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:

    authors: Toussaint HM,Knops W,De Groot G,Hollander AP

    更新日期:1990-06-01 00:00:00

  • Development of a novel eccentric arm cycle ergometer for training the upper body.

    abstract:UNLABELLED:Several investigators have demonstrated that chronic eccentric leg cycling is an effective method for improving lower body neuromuscular function (e.g., quadriceps muscle size, strength, and mobility) in a variety of patient and athletic populations. To date, there are no reports of using eccentric arm cycli...

    journal_title:Medicine and science in sports and exercise

    pub_type: 临床试验,杂志文章

    doi:10.1249/MSS.0b013e318269c79c

    authors: Elmer SJ,Danvind J,Holmberg HC

    更新日期:2013-01-01 00:00:00

  • Efficacy of Tandem Gait to Identify Impaired Postural Control after Concussion.

    abstract:PURPOSE:The purpose was to evaluate tandem gait (TG), Balance Error Scoring System (BESS), and modified Balance Error Scoring System (mBESS) performance acutely after concussion in collegiate student-athletes. In addition, we sought to evaluate the psychometric properties of TG, including minimal detectable change (MDC...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000001540

    authors: Oldham JR,Difabio MS,Kaminski TW,Dewolf RM,Howell DR,Buckley TA

    更新日期:2018-06-01 00:00:00

  • Knee joint in soccer players: osteoarthritis and axis deviation.

    abstract::The knee joints of 81 veteran soccer players between ages 40 and 74 were examined. An analysis of and relationships between soccer practice at a top level, osteoarthritis, meniscectomy, and leg axes were evaluated. One-hundred and sixty-two knees were assessed through clinical examination and X-ray examination using a...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/00005768-198508000-00005

    authors: Chantraine A

    更新日期:1985-08-01 00:00:00

  • Hyperthermia during Olympic triathlon: influence of body heat storage during the swimming stage.

    abstract::The purpose of this project was to determine whether mild heat stress induced by wearing a wet suit while swimming in relatively warm water (25.4 +/- 0.1 degrees C) increases the risk of heat injury during the cycling and running stages of an International distance triathlon in a hot and humid environment (32 degrees ...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1097/00005768-199801000-00014

    authors: Kerr CG,Trappe TA,Starling RD,Trappe SW

    更新日期:1998-01-01 00:00:00

  • Effects of High-Intensity Training on Physiological and Hormonal Adaptions in Well-Trained Cyclists.

    abstract:PURPOSE:Investigate development of specific performance adaptions and hormonal responses every fourth week during a 12-wk high-intensity training (HIT) period in groups with different interval-training prescriptions. METHODS:Sixty-three well-trained cyclists performing a 12-wk intervention consisting of two to three H...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章,多中心研究

    doi:10.1249/MSS.0000000000001214

    authors: Sylta Ø,Tønnessen E,Sandbakk Ø,Hammarström D,Danielsen J,Skovereng K,Rønnestad BR,Seiler S

    更新日期:2017-06-01 00:00:00

  • Effects of short-duration and long-duration exercise on lipoprotein(a).

    abstract:PURPOSE:Most studies that use either a single exercise session, exercise training, or a cross-sectional design have failed to find a relationship between exercise and plasma lipoprotein(a) [Lp(a)] concentrations. However, a few studies investigating the effects of longer and/or more strenuous exercise have shown elevat...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1097/00005768-200109000-00014

    authors: Durstine JL,Davis PG,Ferguson MA,Alderson NL,Trost SG

    更新日期:2001-09-01 00:00:00

  • The effects of anabolic steroids on myocardial structure and cardiovascular fitness.

    abstract::To determine the effects of anabolic steroids on myocardial structure, VO2max, and body composition, experienced age-matched male weight trainers (M age 26.5 yr) who either used (U) (N = 11) or did not use (NU) (N = 13) anabolic steroids were evaluated. Steroid users were tested while off cycle (U-OFF) for at least 8 ...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:

    authors: Sachtleben TR,Berg KE,Elias BA,Cheatham JP,Felix GL,Hofschire PJ

    更新日期:1993-11-01 00:00:00

  • Sympathetic nerve activity to nonactive muscle of the exercising and nonexercising limb.

    abstract::The purpose of this study was to determine whether efferent sympathetic nerve activity is different to resting skeletal muscles from the exercising and nonexercising limb. MSNA was measured by microneurography in both legs (peroneal nerve) in six subjects during 2 min of unilateral isometric knee extension (IKE; 10-30...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:

    authors: Ray CA,Mark AL

    更新日期:1995-02-01 00:00:00

  • Maximal blood flow and power output of dog muscle in situ.

    abstract::The two goals of this study were: 1) to establish a stimulation pattern which would drive the gastrocnemius-plantaris muscle of the dog, in situ, to maximal work rate, W, and 2) to determine whether the surgical isolation of the circulation of this muscle, necessary to measure the muscle flow, Q, reduced the muscle's ...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/00005768-198810001-00003

    authors: Stainsby WN,Andrew GM

    更新日期:1988-10-01 00:00:00

  • Fitness during Breast Cancer Treatment and Recovery in an Athlete: A Case Study.

    abstract:PURPOSE:This is a case study of an aerobically trained, multisport, female athlete (age = 39) diagnosed with stage IIIc human epidermal growth factor receptor 2 positive breast cancer. The focus of the study is on measures of cardiorespiratory fitness (V˙O2peak) through the course of cancer therapy. METHODS:A symptom-...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000000987

    authors: Savage PD,Dittus K,Lakoski SG

    更新日期:2016-10-01 00:00:00

  • Associations of Low- and High-Intensity Light Activity with Cardiometabolic Biomarkers.

    abstract:PURPOSE:Light-intensity physical activity (LIPA) accounts for much of adults' waking hours (≈40%) and substantially contributes to overall daily energy expenditure. Encompassing activity behaviors of low intensity (standing with little movement) to those of higher intensity (slow walking), LIPA is ubiquitous, yet littl...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000000631

    authors: Howard B,Winkler EA,Sethi P,Carson V,Ridgers ND,Salmon JO,Healy GN,Owen N,Dunstan DW

    更新日期:2015-10-01 00:00:00

  • Abatement of exertional perceptions following dynamic exercise: physiological mediators.

    abstract::Perceptual and physiological congruity was examined during recovery from high-intensity dynamic exercise. Nine males (24.8 +/- 0.6 yr; VO2max; 52.3 +/- 1.5 ml.kg-1.min-1) undertook in random order four maximal treadmill protocols. Treadmill speed was held constant (5.3 km.h-1) while grade was incremented by 2, 4, 6, o...

    journal_title:Medicine and science in sports and exercise

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Robertson RJ,Nixon PA,Caspersen CJ,Metz KF,Abbott RA,Goss FL

    更新日期:1992-03-01 00:00:00

  • Cost-effective selection of fire fighter recruits.

    abstract::To discriminate suitable fire fighters from recurring large groups of applicants, an objective test battery was developed which screened applicants on the basis of physical, psychomotor, and mental abilities. The physical and psychomotor selection procedures first involved fundamental tests of general aerobic enduranc...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/00005768-198512000-00007

    authors: Brownlie L,Brown S,Diewert G,Good P,Holman G,Laue G,Banister E

    更新日期:1985-12-01 00:00:00

  • Lower-limb coordination and shoulder joint mechanics in the tennis serve.

    abstract:PURPOSE:To examine the relationship between variable lower-limb coordination and shoulder joint kinetics and kinematics in the high-performance flat first serve in tennis. METHODS:Three-dimensional data describing three flat serve (FS) techniques, each executed with varying lower-limb involvement: foot-up (FU), foot-b...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/mss.0b013e31815c6d61

    authors: Reid M,Elliott B,Alderson J

    更新日期:2008-02-01 00:00:00

  • Introduction to the symposium: resistive weight training: a new approach to exercise for cardiac and coronary disease prone populations.

    abstract::This symposium is concerned with the use of resistive exercise in cardiac and coronary prone populations. In the past, these populations have been refrained from resistive exercise. However, recent studies suggest that this form of exercise is safe and has favorable effects on physical fitness, cardiac risk factors su...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:

    authors: Stewart KJ

    更新日期:1989-12-01 00:00:00

  • Effects of step rate manipulation on joint mechanics during running.

    abstract:PURPOSE:the objective of this study was to characterize the biomechanical effects of step rate modification during running on the hip, knee, and ankle joints so as to evaluate a potential strategy to reduce lower extremity loading and risk for injury. METHODS:three-dimensional kinematics and kinetics were recorded fro...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0b013e3181ebedf4

    authors: Heiderscheit BC,Chumanov ES,Michalski MP,Wille CM,Ryan MB

    更新日期:2011-02-01 00:00:00

  • Exercise-induced Changes in Soluble ST2 Concentrations in Marathon Runners.

    abstract:PURPOSE:Previous studies have suggested that extreme endurance exercise may induce cardiac microdamage that could lead to subsequent myocardial fibrosis. Soluble suppression of tumorigenicity 2 (sST2) is a cardiac biomarker for assessment of myocardial fibrosis, inflammation, and strain. We evaluated baseline and exerc...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000001806

    authors: Aengevaeren VL,VAN Kimmenade RRJ,Hopman MTE,VAN Royen N,Snider JV,Januzzi JL,George KP,Eijsvogels TMH

    更新日期:2019-03-01 00:00:00

  • Effect of High-Intensity Training and Asthma on the V˙O2 Kinetics of Adolescents.

    abstract:PURPOSE:High-intensity interval training (HIIT) represents a potent stimulus to the dynamic oxygen uptake (V˙O2) response in adults, but whether the same is evident in youth is unknown. HIIT has also been suggested to place a lower demand on the respiratory system, decreasing the likelihood of exacerbation in those wit...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000002270

    authors: McNarry MA,Winn CON,Davies GA,Eddolls WTB,Mackintosh KA

    更新日期:2020-06-01 00:00:00

  • Scheduled exercise phase shifts the circadian clock in skeletal muscle.

    abstract:PURPOSE:It has been well established in mammals that circadian behavior as well as the molecular clockwork can be synchronized to the light-dark cycle via the suprachiasmatic nucleus of the hypothalamus (SCN). In addition to light, it has been demonstrated that nonphotic time cues, such as restricting the time of food ...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0b013e318255cf4c

    authors: Wolff G,Esser KA

    更新日期:2012-09-01 00:00:00

  • Explosive force and fractionated reaction time in elderly low- and high-active women.

    abstract:PURPOSE:The purpose of this study was to determine whether muscle power, activation time, and neuromuscular stimulation are related to physical activity patterns in older women. METHODS:Forty women (65-84 yr) were assigned to high-active (HA) and low-active (LA) groups on the basis of a historical activity questionnai...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/mss.0b013e318074ccd9

    authors: Laroche DP,Knight CA,Dickie JL,Lussier M,Roy SJ

    更新日期:2007-09-01 00:00:00

  • Power Training-induced Increases in Muscle Activation during Gait in Old Adults.

    abstract:INTRODUCTION/PURPOSE:Aging modifies neuromuscular activation of agonist and antagonist muscles during walking. Power training can evoke adaptations in neuromuscular activation that underlie gains in muscle strength and power but it is unknown if these adaptations transfer to dynamic tasks such as walking. We examined t...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000001345

    authors: Beijersbergen CMI,Granacher U,Gäbler M,Devita P,Hortobágyi T

    更新日期:2017-11-01 00:00:00

  • The isometric torque at which knee-extensor muscle reoxygenation stops.

    abstract:PURPOSE:We investigated the knee-extensor torque at which reoxygenation (inflow of arterial blood) during an isometric contraction stopped, whether this torque depended on maximal torque capacity (MTC), and whether there were differences among the synergists. METHODS:Isometric knee-extension torque was measured using ...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/mss.0b013e31802dd3cc

    authors: de Ruiter CJ,Goudsmit JF,Van Tricht JA,de Haan A

    更新日期:2007-03-01 00:00:00

  • Prior arm exercise speeds the VO2 kinetics during arm exercise above the heart level.

    abstract:PURPOSE:To test the hypothesis that the initial O2 uptake kinetics during exercise where the rise in blood flow (and, by implication, O2 delivery) to the working muscles during an abrupt increase in exercise intensity is reduced (i.e., arm exercise performed above the level of the heart) would be faster when preceded b...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/01.mss.0000159013.20244.f8

    authors: Koppo K,Bouckaert J

    更新日期:2005-04-01 00:00:00