Abstract:
PURPOSE:Most studies that use either a single exercise session, exercise training, or a cross-sectional design have failed to find a relationship between exercise and plasma lipoprotein(a) [Lp(a)] concentrations. However, a few studies investigating the effects of longer and/or more strenuous exercise have shown elevated Lp(a) concentrations, possibly as an acute-phase reactant to muscle damage. Based on the assumption that greater muscle damage would occur with exercise of longer duration, the purpose of the present study was to determine whether exercise of longer duration would increase Lp(a) concentration and creatine kinase (CK) activity more than exercise of shorter duration. METHODS:Ten endurance-trained men (mean +/- SD: age, 27 +/- 6 yr; maximal oxygen consumption [VO(2max)], 57 +/- 7 mL x kg(-1) x min(-1)) completed two separate exercise sessions at 70% VO(2max). One session required 800 kcal of energy expenditure (60 +/- 6 min), and the other required 1500 kcal (112 +/- 12 min). Fasted blood samples were taken immediately before (0-pre), immediately after (0-post), 1 d after (1-post), and 2 d after (2-post) each exercise session. RESULTS:CK activity increased after both exercise sessions (mean +/- SE; 800 kcal: 0-pre 55 +/- 11, 1-post 168 +/- 64 U x L(-1) x min(-1); 1500 kcal: 0-pre 51 +/- 5, 1-post 187 +/- 30, 2-post 123 +/- 19 U x L(-1) x min(-1); P < 0.05). However, median Lp(a) concentrations were not altered by either exercise session (800 kcal: 0-pre 5.0 mg x dL(-1), 0-post 3.2 mg x dL(-1), 1-post 4.0 mg x dL(-1), 2-post 3.4 mg x dL(-1); 1500 kcal: 0-pre 5.8 mg x dL(-1), 0-post 4.3 mg x dL(-1), 1-post 3.2 mg x dL(-1), 2-post 5.3 mg x dL(-1)). In addition, no relationship existed between exercise-induced changes in CK activity and Lp(a) concentration (800 kcal: r = -0.26; 1500 kcal: r = -0.02). CONCLUSION:These results suggest that plasma Lp(a) concentration will not increase in response to minor exercise-induced muscle damage in endurance-trained runners.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Durstine JL,Davis PG,Ferguson MA,Alderson NL,Trost SGdoi
10.1097/00005768-200109000-00014subject
Has Abstractpub_date
2001-09-01 00:00:00pages
1511-6issue
9eissn
0195-9131issn
1530-0315journal_volume
33pub_type
杂志文章abstract:PURPOSE:To examine the relationship of physical activity and its changes over a 9-yr follow-up to the prevalence of metabolic syndrome (MetS) in 2060 young adults (24-39 yr) enrolled in the Cardiovascular Risk in Young Finns Study. METHODS:Leisure-time physical activity (LTPA) was assessed using a self-report question...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e318172ced4
更新日期:2008-08-01 00:00:00
abstract::Maximal lactate steady state (MLSS) refers to the upper limit of blood lactate concentration indicating an equilibrium between lactate production and lactate elimination during constant workload. The aim of the present study was to investigate whether different levels of MLSS may explain different blood lactate concen...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199602000-00013
更新日期:1996-02-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:10.1249/01.mss.0000176302.99185.be
更新日期:2005-11-01 00:00:00
abstract:INTRODUCTION:Poor muscle quality and sedentary behavior are risk factors for metabolic dysfunction in children and adolescents. However, because longitudinal data are scarce, relatively little is known about how changes in muscle quality and physical activity influence bone development. PURPOSE:In a 2-yr longitudinal ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e31829c32fe
更新日期:2013-12-01 00:00:00
abstract:PURPOSE:To determine whether physical activity and fitness change in girls with and without a predisposition to obesity from 8 to 10 yr of age. METHODS:Normal-weight girls (N = 91) were recruited at 8 yr of age according to parental body mass index (BMI): LN = girls with two lean (BMI < 25 kg.m-2) parents, LNOB = girl...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.MSS.0000113666.98463.B0
更新日期:2004-02-01 00:00:00
abstract:PURPOSE:The reliability of athletes to recall and self-report a concussion history has never been quantified. This study examined the reliability of the self-report concussion history measure and explored determinants of recall in the number of self-reported concussions in a group of retired professional football playe...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e31823240f2
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:Heart rate (HR) is widely used to adjust exercise intensity in aerobic training. Training HR recommendations are calculated often from simple equations. Because at lactate steady state (LASS) may be an intensity of exercise eliciting similar objective measures of intensity and similar subjective measures of met...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200205000-00024
更新日期:2002-05-01 00:00:00
abstract:PURPOSE:To investigate the effects of speech production on physiological responses during sub maximal exercise of various intensities. METHODS:Three constant levels running at work intensities corresponding to 65%, 75%, and 85% of the subjects' (N = 14) VO(2) max were performed with and without talking. These loads we...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200208000-00016
更新日期:2002-08-01 00:00:00
abstract::We hypothesized that the structure of systemic arteries would be altered following 10-14 wk of hindlimb unloading (tail suspension) in female Sprague-Dawley rats. Tail suspension resulted in atrophy of the soleus muscle (P < or = 0.01) but no significant differences in the mass of the extensor digitorum muscle, heart,...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199710000-00005
更新日期:1997-10-01 00:00:00
abstract::The ventilatory stimulating effects of hypoxia occurring at carotid bodies are potentiated by exercise. However, hypoxia also has central ventilatory depressive effects; the potential interactions between this hypoxic depression and exercise have not been studied. We examined the ventilatory response to a 20 min perio...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1991-06-01 00:00:00
abstract::We compared physiological and perceptual responses to non-weight bearing (cycle) and weight bearing (treadmill) exercise in 16 sedentary women throughout a normal term pregnancy. Subjects were recruited late in the first trimester (less than 13 wk gestation) and were studied at 4 wk intervals throughout pregnancy and ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1991-04-01 00:00:00
abstract:PURPOSE:To validate the 7-d Physical Activity Recall (PAR) telephone interview version and its activity intensity categories. METHODS:Seventy-four adults (47 women, 27 men), ranging in age (18-67) and activity levels, were interviewed by phone and in-person using the same PAR protocol. Each participant wore a TriTrac-...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.MSS.0000064941.43869.4E
更新日期:2003-05-01 00:00:00
abstract:UNLABELLED:Accurate assessment of physical activity (PA) is necessary to identify the sedentary older individual who is in need of activity intervention. Activity monitors are quite popular, although it has been suggested that they are less accurate at slow gait speeds. PURPOSE:To examine the accuracy of the three act...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/mss.0b013e318158b504
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:A twin design was used to test whether the association between exercise behavior and heart rate and the association between exercise behavior and respiratory sinus arrhythmia (RSA) derive from a common genetic factor. METHODS:Data were available from 157 adolescent (aged 13-22) and 208 middle-aged twin pairs (...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.MSS.0000079073.20399.11
更新日期:2003-08-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001740
更新日期:2018-12-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1992-11-01 00:00:00
abstract:INTRODUCTION AND PURPOSE:Physical inactivity in postmenopausal women contributes to a rise in atherogenic risk factors associated with the metabolic syndrome. Although regular physical activity positively contributes to health, inactivity progressively increases with age. The Dose Response to Exercise in Women aged 45-...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1249/01.MSS.0000113738.06267.E5
更新日期:2004-02-01 00:00:00
abstract:PURPOSE:Investigate development of specific performance adaptions and hormonal responses every fourth week during a 12-wk high-intensity training (HIT) period in groups with different interval-training prescriptions. METHODS:Sixty-three well-trained cyclists performing a 12-wk intervention consisting of two to three H...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,多中心研究
doi:10.1249/MSS.0000000000001214
更新日期:2017-06-01 00:00:00
abstract::Ski charging was measured using giant-slalom style skis as gliding capacitors. The voltage measured across the plates was proportional to the charge on the base. While resting on dry snow or suspended in the air, the voltage was slowly reduced by the data logger itself. On wet snow the decay was much faster. While sta...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::Chronically increased contractile activity by low-frequency stimulation induces a transformation of fast- into slow-twitch muscle fibers in the rabbit. This transformation is progressive with the duration of the stimulation and affects various functional systems of the muscle fiber in an orderly sequence. Early change...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:
更新日期:1984-12-01 00:00:00
abstract::This study assessed body density (BD) in an ethnically diverse sample of women (African American, Caucasian, Mexican American and Native American) (N = 139) who were between 20 and 30 or 40 and 50 yr of age and of normal weight for their height. BD was assessed using three methods: hydrostatically determined density (...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199701000-00013
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Sensitization of mechanosensitive afferents, which contribute to the exercise pressor reflex, has been recognized as a characteristic of patients with heart failure (HF); however, the hemodynamic implications of this hypersensitivity are unclear. OBJECTIVES:The present study used passive leg movement (PLM) ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000782
更新日期:2016-03-01 00:00:00
abstract::We investigated the relationship of aerobic fitness to the response of volume-regulating hormones to acute simulated microgravity. Six untrained (UT) and six endurance-trained (ET) healthy young males were studied in the head-down tilt (HDT) position of -6 degrees for 4 h. Peak oxygen uptake (VO2peak) and plasma volum...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1992-09-01 00:00:00
abstract:INTRODUCTION:Recent data indicate a direct relationship between the sympathetic nervous system and bone metabolism. The purpose of this study was to evaluate the effects of a beta-1 adrenergic (Adrb1) agonist, dobutamine (DOB), on disuse-induced changes in bone integrity during 28 d of hindlimb unloading (HU). METHODS...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e31828d39bc
更新日期:2013-09-01 00:00:00
abstract:PURPOSE:To examine the relationship between physical activity and levels of plasma lipid peroxides, superoxide dismutase in erythrocytes (SOD), and glutathione peroxidase (GSH-Px) in whole blood activities. METHODS:Cross-sectional study in 488 Spanish women. Two categories of leisure time physical activity were define...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200205000-00014
更新日期:2002-05-01 00:00:00
abstract::The purpose of the study was to examine the effects of surgical and nonsurgical treatment of previously immobilized ankle fractures on voluntary and evoked contractile properties before and following fatigue. Twelve control and 12 previously immobilized (4-14 wk postfracture) internally fixated and nonfixated ankles w...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199709000-00001
更新日期:1997-09-01 00:00:00
abstract:PURPOSE:Orienteering athletes must adapt to running on various surfaces, with biomechanics likely contributing to performance. Here, our aims were to identify the effect of athletic status and of surface on the running biomechanics of orienteers. METHODS:Seven elite and seven amateur male orienteers ran 20 m on road, ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000413
更新日期:2015-02-01 00:00:00
abstract:PURPOSE:The present longitudinal study assessed cardiorespiratory capacity and running economy of Olympic athletes over several decades to measure changes in fitness in an elite group during aging. METHODS:Twenty-six male runners training for the 1968 Olympics were recruited. HR, V˙O2max, ventilation, and running econ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001407
更新日期:2018-01-01 00:00:00
abstract:INTRODUCTION/PURPOSE:Hyperpnea and hyperinflation have been proposed as contributors to exaggerated energy demands in chronic obstructive pulmonary disease (COPD), yet there are incomplete data on exercise requirements. This study compared total-body energy demands of the internal (unloaded) and external work of cyclin...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/mss.0b013e3180383d50
更新日期:2007-06-01 00:00:00
abstract:PURPOSE:Cross-sectional studies suggest that training can increase muscle carnosine (MCarn), although longitudinal studies have failed to confirm this. A lack of control for dietary β-alanine intake or muscle fiber type shifting may have hampered their conclusions. The purpose of the present study was to investigate th...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000001697
更新日期:2018-11-01 00:00:00