Abstract：
PURPOSE:Despite the growing research interest in vascular adaptations to exercise training over the last few decades, it remains unclear whether microvascular function in healthy subjects can be further improved by regular training. Herein, we sought to systematically review the literature and determine whether microvascular dilator function is greater in athletes compared to age-matched healthy untrained subjects. METHODS:We conducted a systematic search of MEDLINE, Cochrane, EMBASE, and Web of Science since their inceptions until October 2013 for articles evaluating indices of primarily microvascular endothelium-dependent or endothelium-independent dilation (MVEDD and MVEID, respectively) in athletes. A meta-analysis was performed to determine the standardized mean difference (SMD) in MVEDD and MVEID between athletes and age-matched controls. Subgroup analyses were used to study potential moderating factors. RESULTS:Thirty-six studies were selected after systematic review, comprising 521 athletes (506 endurance-trained and 15 endurance- and strength-trained) and 496 age-matched control subjects. After data pooling, athletes presented higher MVEDD (31 studies; SMD, 0.47; P < 0.00001) and MVEID (14 studies; SMD, 0.51; P < 0.00001) compared with the control subjects. Similar results were observed in young (younger than 40 yr) and master (older than 55 yr) athletes when analyzed separately. CONCLUSION:Both young and master athletes present enhanced microvascular function compared with age-matched untrained but otherwise healthy subjects. These data provide evidence of a positive association between exercise training and microvascular function in the absence of known underlying cardiovascular disease.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Montero D,Walther G,Diaz-Cañestro C,Pyke KE,Padilla Jdoi
10.1249/MSS.0000000000000567subject
Has Abstractpub_date
2015-07-01 00:00:00pages
1485-94issue
7eissn
0195-9131issn
1530-0315journal_volume
47pub_type
杂志文章,meta分析,评审abstract：:Sudden cardiac death is always a tragedy. Sudden death during sport is particularly poignant because people tend to associate sport with health and fitness. Both the public and the medical profession would like to prevent such events, and preparticipation medical screening is often promoted as one such method. When we...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：10.1097/00005768-199810001-00002
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abstract：:Thirty-eight athletes with unilateral patellar tendinopathy (17 with a tendinopathy of the main body of the tendon, and 21 with an insertional tendinopathy) underwent ultrasound-guided multiple percutaneous longitudinal tenotomy under local anaesthetic infiltration after failure of conservative management. Thirty-four...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
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abstract：PURPOSE:Greater resistance to muscle fatigue has been observed in women versus men and in older versus young individuals. As suggested mechanisms for these differences include task intensity and duty cycle, the purpose of this study was to evaluate fatigue in healthy young and older men and women during maximum-effort ...
journal_title：Medicine and science in sports and exercise
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journal_title：Medicine and science in sports and exercise
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journal_title：Medicine and science in sports and exercise
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doi：
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
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journal_title：Medicine and science in sports and exercise
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journal_title：Medicine and science in sports and exercise
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1993-08-01 00:00:00
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journal_title：Medicine and science in sports and exercise
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pub_type： 临床试验,杂志文章
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
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journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1992-02-01 00:00:00
abstract：PURPOSE:Arterial distensibility decreases with age. This decrease may be associated with the initiation and/or progression of hypertension and atherosclerosis and may be attenuated by positive lifestyle habits, including habitual physical activity. We tested the hypothesis that self-reported sport, leisure, and work ph...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200112000-00014
更新日期：2001-12-01 00:00:00
