Abstract:
:Endocrine effects of self-administration of high doses of anabolic steroids and testosterone were investigated in five power athletes during 26 wk of training, and for the following 12-16 wk after drug withdrawal. After 26 wk of anabolic steroid and testosterone administration, serum testosterone concentrations had increased 2.3-fold. This was associated with increased concentrations of serum estradiol, which rose 7-fold to values (0.48 nmol X 1(-1) typical for females. There was a major decrease in serum FSH and LH concentrations, but they returned to control levels following drug withdrawal. However, serum testosterone concentrations stayed at low levels (9 nmol X 1(-1) ) during this follow-up period, indicating long-lasting impairment of testicular endocrine function. Serum ACTH concentrations were also decreased during steroid administration, possibly due to a corticoid-like effect of some of the anabolic steroids taken in high doses. However, no changes were seen in serum cortisol. The only consistent change in the control group was an increase in serum LH concentrations during the most intensive training, suggesting that a decreasing tendency of serum testosterone was compensated for by augmented LH secretion.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Alén M,Reinilä M,Vihko Rsubject
Has Abstractpub_date
1985-06-01 00:00:00pages
354-9issue
3eissn
0195-9131issn
1530-0315journal_volume
17pub_type
杂志文章abstract:UNLABELLED:Considerable evidence suggests regular physical activity can reduce chronic pain symptoms. The dysfunction of endogenous facilitatory and inhibitory systems has been implicated in multiple chronic pain conditions. However, few studies have investigated the relationship between levels of physical activity and...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3182a69cf1
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:To assess the biologic basis of massage therapies, we developed an experimental approach to mimic Swedish massage and evaluate this approach on recovery from eccentric exercise-induced muscle damage using a well-controlled animal model. METHODS:Tibialis anterior muscles of six New Zealand White rabbits were su...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e31816c4e12
更新日期:2008-07-01 00:00:00
abstract::Equations are often used to predict cardiorespiratory fitness (CRF) from submaximal or maximal exercise tests. However, no study has comprehensively compared these exercise-based equations with directly measured CRF using data from a single, large cohort. PURPOSE:This study aimed to compare the accuracy of exercise-b...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002435
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:Considering the different loading and training characteristics of the sports practiced during growth, it is important to specify and categorize the bone and soft tissue adaptations in adolescent athletes. This study aimed to categorize 10 different loading sports and a nonsport group and identify the difference...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002420
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:This study tested the hypothesis that exercise training improves myocardial blood flow and regional myocardial contractile function in a lateral border zone located adjacent to the ischemic zone during coronary artery occlusion. METHODS:Fourteen dogs were subjected to either 12 wk of dynamic exercise training ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200104000-00008
更新日期:2001-04-01 00:00:00
abstract:PURPOSE:This study aimed 1) to define the principal components of physical function assessed by 10 common lower extremity physical performance tests and 2) to derive a reduced-item set of physical performance tests that efficiently and accurately measures raw performance and limb symmetry on each underlying component i...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002422
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:To compare training loads between men and women during 14 wk of British Army standard entry basic training. METHODS:Thirty-one male (mean ± SD: age, 21 ± 4 yr; height, 1.78 ± 0.08 m; mass, 77.1 ± 10.5 kg) and 28 female (age, 22 ± 4 yr; height, 1.65 ± 0.05 m; mass, 63.9 ± 8.9 kg) British Army recruits had exter...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001716
更新日期:2018-12-01 00:00:00
abstract::The coordination of blood flow control in exercising skeletal muscle is exemplified by the interaction among muscle fibers, nerves, and the smooth muscle and endothelial cells which comprise the resistance vasculature. During functional hyperemia in active muscle, maximal flow exceeds resting values by 10- to 50-fold,...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:
更新日期:1995-08-01 00:00:00
abstract::Sixteen untrained males, age 46 +/- 11 yr (mean +/- SD), were studied to determine the effects of 20 wk of strength training on lipoprotein-lipid profiles and post-heparin lipase activities. All subjects had abnormal lipoprotein-lipid profiles and at least two other risk factors for coronary heart disease (CHD). To co...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1991-10-01 00:00:00
abstract:PURPOSE:Ultraendurance exercise is steadily growing in popularity; however, the effect of increasingly prolonged durations of exercise on the vascular endothelium is unknown. The aim of this study was to characterize the effect of various ultramarathon running distances on vascular form and function. METHODS:We evalua...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002493
更新日期:2020-08-15 00:00:00
abstract:PURPOSE:The objective of this study is to determine the effect of body mass index (BMI) on level of agreement between six previously established prediction equations for three commonly used accelerometers to predict summary measures of energy expenditure (EE) in youth. METHODS:One hundred and thirty-one youth between ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e318267b8f1
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:We transposed the concept of effectiveness of force application used in pedaling mechanics to calculate the ratio of forces (RF) during sprint running and tested the hypothesis that field sprint performance was related to the technical ability to produce high amounts of net positive horizontal force. This abili...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e318216ea37
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:The purposes of this study was to determine functional movement assessments' ability to predict head impact biomechanics in college football players and to determine whether head impact biomechanics could explain preseason to postseason changes in functional movement performance. METHODS:Participants (N = 44; ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001538
更新日期:2018-06-01 00:00:00
abstract:PURPOSE:the objective of this study was to characterize the biomechanical effects of step rate modification during running on the hip, knee, and ankle joints so as to evaluate a potential strategy to reduce lower extremity loading and risk for injury. METHODS:three-dimensional kinematics and kinetics were recorded fro...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3181ebedf4
更新日期:2011-02-01 00:00:00
abstract:UNLABELLED:Theoretically, critical torque (CT) is the maximal isometric torque that can be maintained without fatigue, and anaerobic work capacity (AWC) is the total "isometric work" associated with stored energy sources within the muscle. PURPOSE:The purpose of this study was twofold: 1) to determine whether there we...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3181ab8cc0
更新日期:2009-12-01 00:00:00
abstract:PURPOSE:One purpose was to test the hypothesis that anxiety reductions following exercise are caused by a "time out" from daily cares and worries, and the second purpose was to document the magnitude of the change in state anxiety after exercise in high trait anxious females. METHODS:Anxious women (N = 14) completed f...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00005768-199807000-00013
更新日期:1998-07-01 00:00:00
abstract:UNLABELLED:Although effects of workload and cadence on sagittal plane knee biomechanics in cycling have been widely studied, few studies have examined their impact on the frontal plane. PURPOSE:The purpose of this study was to investigate the effects of different workloads and cadences on knee sagittal and frontal pla...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000000759
更新日期:2016-02-01 00:00:00
abstract:PURPOSE:During and following exercise there are a number of changes in pulmonary function, among which is a decrease in forced vital capacity (FVC). Several potential mechanisms may explain this decreased FVC, including an exercise-induced increase in thoracic blood volume. METHODS:We tested the hypothesis that altere...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199807000-00003
更新日期:1998-07-01 00:00:00
abstract:PURPOSE:The purpose of this study was to examine the impact of exercise-induced metabolic stress on hormonal responses and chronic muscular adaptations. METHODS:We compared the acute and long-term effects of an "NR regimen" (no-rest regimen) and those of a "WR regimen" (regimen with rest period within a set). Twenty-s...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:2005-06-01 00:00:00
abstract:PURPOSE:To investigate the Epstein-Barr virus (EBV) serostatus in an athletic endurance population, especially the prevalence of complex aberrant EBV antibody patterns. In addition, the purpose was to determine whether serology in athletes is more complex than in the general population. METHODS:The study protocol incl...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000230122.91264.3f
更新日期:2006-10-01 00:00:00
abstract:PURPOSE:We evaluated the impact of anthracyclines on left ventricular function and myocardial tissue characteristics using cardiovascular magnetic resonance (CMR) imaging to determine their relationship with V˙O2peak. METHODS:Women with breast cancer who had not yet received treatment (No-AT, n = 16) and had received ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002469
更新日期:2021-02-01 00:00:00
abstract::We investigated the breath-by-breath pattern of ventilatory response to bicycle exercise in seven elite male cyclists (VO2max = 71.7 ml X min-1 X kg-1) and ten sedentary males (VO2max = 47.3 ml X min-1 X kg-1) to analyze differences in breathing patterns between individuals with normal and high exercise ventilations (...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract:INTRODUCTION:We examined the relationships between insulin-like growth factor I (IGF-I), its binding protein (IGFBP-3), body composition, and bone mineral density (BMD) in collegiate runners (N = 13), gymnasts (N = 10), and noncompetitive women (N = 10). METHODS:Subjects were evaluated by dual-energy x-ray absorptiome...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200011000-00013
更新日期:2000-11-01 00:00:00
abstract::Potential physiological, anthropometric, and training determinants of running economy (RE) were studied in a heterogeneous group of habitual distance runners (N = 188, 119 males, 69 females). RE was measured as VO2 (ml.kg-1.min-1) during level treadmill running at 161 m.min-1 (6 mph) (VO2-6). Examined as potential det...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1992-10-01 00:00:00
abstract:PURPOSE:The purpose of this study was to investigate the influence of different cycling cadences on metabolic and kinematic parameters during subsequent running. METHODS:Eight triathletes performed two incremental tests (running and cycling) to determine maximal oxygen uptake (VO2max) and ventilatory threshold (VT) va...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00005768-200203000-00022
更新日期:2002-03-01 00:00:00
abstract:UNLABELLED:Cell-derived procoagulant microparticles (MP) might be able to contribute to exercise-induced changes in blood hemostasis. PURPOSES:This study aimed to examine (i) the concentration and procoagulant activity of cell-derived MP after a moderate endurance exercise and (ii) the differences in the release, clea...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:10.1249/MSS.0b013e3182068645
更新日期:2011-07-01 00:00:00
abstract:PURPOSE:Overtraining is primarily related to sustained high load training, often coupled with other stressors. Studies in animal models have suggested that unremittingly heavy training (monotonous training) may increase the likelihood of developing overtraining syndrome. The purpose of this study was to extend our prel...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199807000-00023
更新日期:1998-07-01 00:00:00
abstract:PURPOSE:The purpose of this study was to investigate the vibrotactile detection thresholds of the plantar cutaneous afferents in subjects with chronic ankle instability compared with healthy control subjects. METHODS:Eight adults with chronic ankle instability and eight adults with no ankle sprain history participated...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3182390212
更新日期:2012-04-01 00:00:00
abstract:PURPOSE:To examine whether normalized quadriceps and hamstring strength would predict quadriceps and hamstring muscle activation amplitudes and whether these neuromuscular factors would predict knee kinematics and kinetics during a drop jump task. METHODS:Thirty-nine females and 39 males were measured for isometric qu...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3181e3b3f
更新日期:2009-04-01 00:00:00
abstract:PURPOSE:According to the force-velocity relationship of human skeletal muscle, the maximal load one can lift is limited by the concentric movement phase, and the eccentric phase is always underloaded. In the present study, we hypothesized that acute exercise training using an eccentric overload compared with standard l...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00005768-200107000-00020
更新日期:2001-07-01 00:00:00