Abstract:
PURPOSE:According to the force-velocity relationship of human skeletal muscle, the maximal load one can lift is limited by the concentric movement phase, and the eccentric phase is always underloaded. In the present study, we hypothesized that acute exercise training using an eccentric overload compared with standard loading would lead to greater neuromuscular and strength adaptations. METHODS:Sedentary women (age 20.9 yr) were tested for concentric and eccentric three-repetition maximum (3RM), maximal isokinetic eccentric and concentric and isometric force and associated EMG activity of selected thigh muscles before and after 7 consecutive days of exercise training of the left quadriceps. The exercise program was designed so that the total weight lifted was similar between the eccentric overload (EO, N = 10) and standard group (ST, N = 10), but EO exercised with about 50% greater eccentric load whereas the controls did not exercise (N = 10). RESULTS:There was a 22% increase in the total weight lifted over 7 d. On the average, EOs compared with STs strength gains were approximately twofold greater. Changes in EMG paralleled the changes in muscle strength without changes in biceps femoris coactivity during knee extension. CONCLUSION:Because the strength gains were achieved by exercising at low intensities and over a short time period, exercise prescription of eccentric overloading appears especially suitable for elders, individuals deconditioned due to an injury, and the chronically diseased.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Hortobágyi T,Devita P,Money J,Barrier Jdoi
10.1097/00005768-200107000-00020subject
Has Abstractpub_date
2001-07-01 00:00:00pages
1206-12issue
7eissn
0195-9131issn
1530-0315journal_volume
33pub_type
临床试验,杂志文章,随机对照试验abstract:PURPOSE:To study the ventilatory effects of closely monitored cycle ergometer conditioning (HR target, 145-150 beats x min(-1); 25 min/session; three sessions per week) during the second and third pregnancy trimesters (TMs) in healthy human pregnancy. METHODS:Subjects were 27 previously sedentary pregnant women (exerc...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199801000-00004
更新日期:1998-01-01 00:00:00
abstract::Forces that are repeatedly applied to the body could lead to positive remodeling of a structure if the forces fall below the tensile limit of the structure and if sufficient time is provided between force applications. On the other hand, an overuse injury could result if there is inadequate rest time between applied f...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:10.1249/01.mss.0000126803.66636.dd
更新日期:2004-05-01 00:00:00
abstract::Low-intensity exercise (less than or equal to 50% VO2max) has been demonstrated to produce heat acclimation (HA) in trained subjects. The purpose of this study was to determine whether shorter-duration, moderate-intensity exercise would also result in HA. Nine trained runners performed two 9-d exercise heat-stress pro...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/00005768-199010000-00012
更新日期:1990-10-01 00:00:00
abstract:INTRODUCTION:The purpose of this study was to validate a parent proxy record of children's physical activity with CSA Model 7164 accelerometers. METHODS:A parent proxy record was developed to record children's activity after school on weekdays and all day long on weekends for 7 d. Parents recorded both duration and in...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000174906.38722.2e
更新日期:2005-08-01 00:00:00
abstract::Muscle fatigue has been studied with a variety approaches, tools and technologies. The foci of these studies have ranged tremendously, from molecules to the entire organism. Single cell and animal models have been used to gain mechanistic insight into the fatigue process. The theme of this review is the concept that t...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:10.1249/MSS.0000000000001052
更新日期:2016-11-01 00:00:00
abstract:INTRODUCTION:It is well established that hemodynamic dysfunction, resulting in diminished upper-extremity work capacity, occurs in persons with spinal cord injury (SCI) as compared with those who are nondisabled (ND). Although it has been shown that persons with paraplegia display higher values of heart rate (HR) with ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200209000-00001
更新日期:2002-09-01 00:00:00
abstract::To determine the effects of anabolic steroids on myocardial structure, VO2max, and body composition, experienced age-matched male weight trainers (M age 26.5 yr) who either used (U) (N = 11) or did not use (NU) (N = 13) anabolic steroids were evaluated. Steroid users were tested while off cycle (U-OFF) for at least 8 ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1993-11-01 00:00:00
abstract:PURPOSE:The increased physiological demand of pregnancy results in profound adaptation of the maternal cardiovascular system, reflected by greater resting cardiac output and left ventricular (LV) deformation. Whether the increased resting demand alters acute cardiac responses to exercise in healthy pregnant women is no...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002554
更新日期:2020-11-03 00:00:00
abstract:PURPOSE AND METHODS:It is commonly recognized that there is familial aggregation for physical activity level. However, the genes and sequence variants responsible for the familial clustering have not been investigated. We performed a genome-wide linkage scan based on 432 markers typed in 767 subjects from 207 families ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.MSS.0000078937.22939.7E
更新日期:2003-08-01 00:00:00
abstract:INTRODUCTION/PURPOSE:Aging modifies neuromuscular activation of agonist and antagonist muscles during walking. Power training can evoke adaptations in neuromuscular activation that underlie gains in muscle strength and power but it is unknown if these adaptations transfer to dynamic tasks such as walking. We examined t...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001345
更新日期:2017-11-01 00:00:00
abstract:PURPOSE:Physical fitness and physical activity tracking data enhance our understanding as to when children settle into their long-term exercise and fitness patterns and, therefore. provide insight as to when programs focusing on preventing sedentary adults behaviors should be initiated. METHODS:In this paper, the trac...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200007000-00011
更新日期:2000-07-01 00:00:00
abstract::The inheritance of cardiac changes during acute dynamic physical exercise was studied in 21 pairs of monozygotic and 12 pairs of dizygotic male twins, ages 18-31 yr. Echocardiography was performed in resting conditions and at submaximal supine bicycle exercise at a heart rate of 110 bpm. In resting conditions signific...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1991-11-01 00:00:00
abstract::In the present studies, the Leuven Tennis Performance Test (LTPT), a newly developed test procedure to measure stroke performance in match-like conditions in elite tennis players, was evaluated as to its value for research purposes. The LTPT is enacted on a regular tennis court. It consists of first and second service...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199808000-00016
更新日期:1998-08-01 00:00:00
abstract:BACKGROUND:Extracellular vesicles (EV) are purported to mediate type 2 diabetes and CVD risk and development. Physical activity and a balanced diet reduce disease risk, but no study has tested the hypothesis that short-term interval (INT) training would reduce EV compared with continuous (CONT) exercise in adults with ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002185
更新日期:2020-03-01 00:00:00
abstract:INTRODUCTION:Inhaled beta2-agonists are important therapeutic agents for the treatment of exercise-induced asthma in athletes but are restricted by international antidoping regulations. PURPOSE:To investigate whether 18 mug of inhaled formoterol affects endurance performance during running at high altitudes until exha...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/01.mss.0000233801.46906.9b
更新日期:2006-12-01 00:00:00
abstract::Psychological consequences of exercise deprivation in habitual exercisers. The purpose of this investigation was to evaluate the influence of 3 d of exercise deprivation on selected psychological variables. Ten volunteers (4 female and 6 male) who regularly exercised 6-7 d.wk-1 for at least 45 min at a time participat...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:10.1097/00005768-199609000-00018
更新日期:1996-09-01 00:00:00
abstract::The utility of a biomechanical evaluation of an injury is shown for an incident involving bilateral tibial spiral fractures during skiing. With incorporation of directly measured binding release forces into a biomechanical model, estimates of torques transmitted to the skier's leg were determined. The analysis reveale...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/00005768-198104000-00007
更新日期:1981-01-01 00:00:00
abstract:PURPOSE:We transposed the concept of effectiveness of force application used in pedaling mechanics to calculate the ratio of forces (RF) during sprint running and tested the hypothesis that field sprint performance was related to the technical ability to produce high amounts of net positive horizontal force. This abili...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e318216ea37
更新日期:2011-09-01 00:00:00
abstract:INTRODUCTION:This study tested the hypothesis that females rely on thermal behavior to a greater extent during and after exercise, relative to males. METHODS:In a 24°C ± 1°C; (45% ± 10% RH) environment, 10 males (M) and 10 females (F) (22 ± 2 yr) cycled for 60 min (metabolic heat production: M, 117 ± 18 W·m; F, 129 ± ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001756
更新日期:2019-01-01 00:00:00
abstract::A group of 103 female weight lifters (WL) and 92 control (C) women answered a survey concerning eating behavior and attitudes (including the Eating Disorder Inventory) and menstrual function. The incidence of menstrual dysfunction, defined as oligomenorrhea plus amenorrhea, was significantly higher for the WL (30%) th...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:PURPOSE:Text books attribute the side pain "stitch" during exercise to changes in blood flow to the viscera, but the little available research favors stretching of visceral ligaments. We therefore induced and modified stitch experimentally to investigate its cause and possible treatments. METHODS:Ten active healthy yo...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00005768-199908000-00014
更新日期:1999-08-01 00:00:00
abstract:PURPOSE:Aerobic training of professional road cyclists is linked to tremendous aerobic capacities that have never been clearly related to what occur in skeletal muscles submitted to a specific exercise. The aim of the present study was to examine specifically metabolic recovery after an incremental cycling exercise per...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000162616.20085.b4
更新日期:2005-05-01 00:00:00
abstract::The objective of the Team Physician Consensus Statement is to provide physicians, school administrators, team owners, the general public, and individuals who are responsible for making decisions regarding the medical care of athletes and teams with guidelines for choosing a qualified team physician and an outline of t...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200004000-00023
更新日期:2000-04-01 00:00:00
abstract:PURPOSE:Lower-limb muscle weakness has often been reported in COPD, and contributes to exercise intolerance. Controversial information is available regarding upper-limb muscle adaptations and the influence of muscle wasting on muscle weakness. We investigated leg and arm muscle function in 59 stable COPD patients (GOLD...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:10.1249/01.mss.0000150082.59155.4f
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:To compare the cardiovascular reactivity response to mental challenge of aerobically trained and untrained preadolescent boys. METHODS:Heart rate (HR) and blood pressure, as well as stroke volume, total peripheral resistance, rate pressure product, and cardiac contractility response in 15 aerobically trained (...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:10.1249/01.MSS.0000078935.78895.8E
更新日期:2003-08-01 00:00:00
abstract:PURPOSE:This study aimed to determine whether physical activity patterns are associated with sleep later at night and if nighttime sleep is associated with physical activity patterns the next day among adult women. METHODS:Women (N = 353) living throughout the United States wore a wrist and a hip accelerometer for 7 d...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001000
更新日期:2016-10-01 00:00:00
abstract::Facial cooling (FC) elicits a marked bradycardia at rest that appears to be reduced during exercise. This study was done to delineate the effects of exercise mediated central command from those of muscle afferent feedback and sympathetic stimulation on the attenuation of the bradycardic effect of FC during the onset o...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199703000-00006
更新日期:1997-03-01 00:00:00
abstract::Sex is a potent modifier of the cardiovascular system because males and females differ in several aspects of the heart's biology and physiology. Epidemiologically, premenopausal women possess a distinct advantage over men in the occurrence of cardiovascular heart disease; however, this advantage shifts to men once a n...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:10.1249/MSS.0b013e3181621311
更新日期:2008-04-01 00:00:00
abstract:INTRODUCTION:The effects of glargine/glulisine insulin regimen on exercise blood glucose (BG) and strategies to limit exercise-induced hypoglycemia are not well documented. Intermittent high-intensity exercise has been proposed to prevent hypoglycemia, but its effect in participants with type 1 diabetes using glargine/...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0b013e31826c6ad3
更新日期:2013-01-01 00:00:00
abstract::Two healthy females and twelve healthy males, aged 19-24 yr, underwent strength training for periods of 9-21 wk. The muscles trained included extensor digitorum brevis (N = 3), soleus (N = 7), brachioradialis (N = 4), and the hypothenar muscles (N = 3). The effect of training on motoneuron excitability was measured as...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00