Abstract:
PURPOSE:This study tested the hypothesis that exercise training improves myocardial blood flow and regional myocardial contractile function in a lateral border zone located adjacent to the ischemic zone during coronary artery occlusion. METHODS:Fourteen dogs were subjected to either 12 wk of dynamic exercise training or cage rest. Dogs were anesthetized and instrumented to assess regional myocardial contractile function (percent segment length shortening and rate of shortening) and regional myocardial blood flow (tracer microspheres) in the central ischemic, lateral border, and nonischemic zones. Measurements were made preocclusion and at 2 min and 3 h after occlusion of the left anterior descending coronary artery (CAO). RESULTS:Contractile function and regional myocardial blood flow were not affected by CAO in the nonischemic zone in both cage-rested and exercise trained dogs. Regional myocardial contractile function and blood flow in the lateral border zone were significantly higher in exercise trained dogs compared with cage-rested dogs, both at 2 min and 3 h after CAO. Ischemic dysfunction was similar in the central ischemic zone in both cage-rested and exercise trained dogs both at 2 min and 3 h after CAO. Regional myocardial blood flow was similarly reduced in the ischemic zone in both groups after 2 min of CAO, but was significantly higher in the inner (subendocardial) region of the exercised trained hearts after 3 h (P < 0.05). CONCLUSION:These data suggest that there was greater border zone perfusion in exercise trained animals during prolonged CAO, which was associated with significantly improved myocardial contractile function.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Brandt MA,Gwirtz PAdoi
10.1097/00005768-200104000-00008subject
Has Abstractpub_date
2001-04-01 00:00:00pages
556-63issue
4eissn
0195-9131issn
1530-0315journal_volume
33pub_type
杂志文章abstract:PURPOSE:This study aimed to examine the effect of altering osmolality or adding sodium alginate and pectin to a concentrated carbohydrate (CHO) beverage on gastric-emptying (GE) rate. METHODS:Boluses (500 mL) of three drinks were instilled double blind in eight healthy men while seated, GE was measured using the doubl...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002301
更新日期:2020-08-01 00:00:00
abstract:UNLABELLED:We previously reported that a mathematical model could accurately predict steady-state road-cycling power when all the model parameters were known. Application of that model to competitive cycling has been limited by the need to obtain accurate parameter values, the non-steady-state nature of many cycling ev...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000193560.34022.04
更新日期:2006-03-01 00:00:00
abstract:INTRODUCTION/PURPOSE:Evidence suggests that carbohydrate and protein (CHO-PRO) ingestion after exercise enhances muscle glycogen repletion to a greater extent than carbohydrate (CHO) alone. However, there is no consensus at this point, and results across studies are mixed, which may be attributable to differences in en...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002476
更新日期:2021-02-01 00:00:00
abstract:PURPOSE:Previous studies have suggested that higher levels of physical activity may lower lung cancer risk; however, few prospective studies have evaluated lung cancer mortality in relation to cardiorespiratory fitness (CRF), an objective marker of recent physical activity habits. METHODS:Thirty-eight thousand men, ag...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3181c47b65
更新日期:2010-05-01 00:00:00
abstract:INTRODUCTION:Common life events, such as getting married or gaining employment, may be opportunities to intervene on health behaviors like physical activity. The purpose of this study was to determine the changes in moderate-to-vigorous physical activity (MVPA) associated with several common life events from adolescenc...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001839
更新日期:2019-04-01 00:00:00
abstract:INTRODUCTION:Inhaled beta2-agonists are important therapeutic agents for the treatment of exercise-induced asthma in athletes but are restricted by international antidoping regulations. PURPOSE:To investigate whether 18 mug of inhaled formoterol affects endurance performance during running at high altitudes until exha...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/01.mss.0000233801.46906.9b
更新日期:2006-12-01 00:00:00
abstract:INTRODUCTION:Competitive female athletes restrict energy intake and increase exercise energy expenditure frequently resulting in ovarian suppression. The purpose of this study was to determine the impact of ovarian suppression and energy deficit on swimming performance (400-m swim velocity). METHODS:Menstrual status w...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3182a32b72
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:Considering the different loading and training characteristics of the sports practiced during growth, it is important to specify and categorize the bone and soft tissue adaptations in adolescent athletes. This study aimed to categorize 10 different loading sports and a nonsport group and identify the difference...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002420
更新日期:2020-12-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000180359.98241.a2
更新日期:2006-01-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e31817b8e9e
更新日期:2008-10-01 00:00:00
abstract::We provide an updated version of the Compendium of Physical Activities, a coding scheme that classifies specific physical activity (PA) by rate of energy expenditure. It was developed to enhance the comparability of results across studies using self-reports of PA. The Compendium coding scheme links a five-digit code t...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200009001-00009
更新日期:2000-09-01 00:00:00
abstract:PURPOSE:The rapidly increasing incidence of Lyme disease has become a serious public health problem. Persistent symptoms of Lyme disease occur in over 40% of the 300,000 new cases diagnosed annually in the United States and often include debilitating musculoskeletal pain, fatigue, and poor health-related quality of lif...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000683
更新日期:2015-11-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000365
更新日期:2014-12-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000166
更新日期:2014-04-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1995-12-01 00:00:00
abstract::In embryonic chicken skeletal muscle, the presence of a ventricular myosin heavy chain (MHC) is demonstrated by reactivity with an anti-ventricular MHC antibody. Developmental repression of the ventricular MHC expression occurs earlier in embryonic fast twitch posterior latissimus dorsi (PLD) than in embryonic slow-to...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:
更新日期:1989-10-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002306
更新日期:2020-08-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1995-02-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1993-02-01 00:00:00
abstract:PURPOSE:Exercise is associated with altered gut microbial composition, but studies have not investigated whether the gut microbiota and associated metabolites are modulated by exercise training in humans. We explored the impact of 6 wk of endurance exercise on the composition, functional capacity, and metabolic output ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001495
更新日期:2018-04-01 00:00:00
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journal_title:Medicine and science in sports and exercise
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000001069
更新日期:2017-01-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:10.1097/00005768-199806000-00020
更新日期:1998-06-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199901000-00010
更新日期:1999-01-01 00:00:00
abstract::Increased vertical impact loading during running has been associated with a variety of running related injuries including stress fractures, patellofemoral pain, and plantar fasciitis. PURPOSE:The purpose of this study was to examine the acute and long-term effect of a gait retraining program aimed at teaching runners...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001710
更新日期:2018-12-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000142310.97274.94
更新日期:2004-10-01 00:00:00
abstract:PURPOSE:The purpose of the study was to explore the utility of school- and county-level variables in explaining variability in children and adolescent body mass index (BMI). METHODS:BMI data from nearly 2.5 million of children and adolescents were aggregated at the school level from more than 5000 schools in Texas. Sc...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001311
更新日期:2017-09-01 00:00:00
abstract::Sex is a potent modifier of the cardiovascular system because males and females differ in several aspects of the heart's biology and physiology. Epidemiologically, premenopausal women possess a distinct advantage over men in the occurrence of cardiovascular heart disease; however, this advantage shifts to men once a n...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:10.1249/MSS.0b013e3181621311
更新日期:2008-04-01 00:00:00
abstract:PURPOSE:Cardiac troponin T (cTnT) is a highly specific marker of myocardial damage and used clinically in the diagnosis of acute myocardial infarction (AMI). Release of cTnT has been demonstrated in several small studies after endurance exercise. The purpose of this study was to explore, using a meta-analytic approach,...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,meta分析
doi:10.1249/mss.0b013e318153ff78
更新日期:2007-12-01 00:00:00
abstract:PURPOSE:To examine the relationship of physical activity and its changes over a 9-yr follow-up to the prevalence of metabolic syndrome (MetS) in 2060 young adults (24-39 yr) enrolled in the Cardiovascular Risk in Young Finns Study. METHODS:Leisure-time physical activity (LTPA) was assessed using a self-report question...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e318172ced4
更新日期:2008-08-01 00:00:00