Abstract:
PURPOSE:Previous studies have suggested that higher levels of physical activity may lower lung cancer risk; however, few prospective studies have evaluated lung cancer mortality in relation to cardiorespiratory fitness (CRF), an objective marker of recent physical activity habits. METHODS:Thirty-eight thousand men, aged 20-84 yr, without history of cancer, received a preventive medical examination at the Cooper Clinic in Dallas, Texas, between 1974 and 2002. CRF was quantified as maximal treadmill exercise test duration and was grouped for analysis as low (lowest 20% of exercise duration), moderate (middle 40%), and high (upper 40%). RESULTS:A total of 232 lung cancer deaths occurred during follow-up (mean = 17 yr). After adjustment for age, examination year, body mass index, smoking, drinking, physical activity, and family history of cancer, hazard ratios (95% confidence intervals) for lung cancer deaths across low, moderate, and high CRF categories were 1.0, 0.48 (0.35-0.67), and 0.43 (0.28-0.65), respectively. There was an inverse association between CRF and lung cancer mortality in former (P for trend = 0.005) and current smokers (P for trend < 0.001) but not in never smokers (trend P = 0.14). Joint analysis of smoking and fitness status revealed a significant 12-fold higher risk of death in current smokers (hazard ratio = 11.9, 95% confidence interval = 6.0-23.6) with low CRF as compared with never smokers who had high CRF. CONCLUSIONS:Although the potential for some residual confounding by smoking could not be eliminated, these data suggest that CRF is inversely associated with lung cancer mortality in men. Continued study of CRF in relation to lung cancer, particularly among smokers, may further our understanding of disease etiology and reveal additional strategies for reducing its burden.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Sui X,Lee DC,Matthews CE,Adams SA,Hébert JR,Church TS,Lee CD,Blair SNdoi
10.1249/MSS.0b013e3181c47b65subject
Has Abstractpub_date
2010-05-01 00:00:00pages
872-8issue
5eissn
0195-9131issn
1530-0315journal_volume
42pub_type
杂志文章abstract:UNLABELLED:The protective effects of cardiorespiratory fitness (CRF) on hypertension (HTN) are well known; however, the association between muscular strength and incidence of HTN has yet to be examined. PURPOSE:This study evaluated the strength-HTN association with and without accounting for CRF. METHODS:Participants...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3181b2f0a4
更新日期:2010-02-01 00:00:00
abstract:PURPOSE:To continuously measure core temperature (T(c)) and heart rate(HR), and quantify fluid balance during a 21-km mass-participation road racein warm, humid environmental conditions. METHODS:Eighteen heat-acclimatized male soldiers ingested a telemetric Tc sensor on the evening prior to the race and wore an ambula...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000218134.74238.6a
更新日期:2006-05-01 00:00:00
abstract:PURPOSE:Compelling evidence suggests larger performance decrements during hypoxic versus normoxic repeated sprinting. Yet the underlying mechanical alterations have not been thoroughly investigated. Therefore, we examined the effects of different levels of normobaric hypoxia on running mechanical performance during rep...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000000937
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:This study aimed to test whether environmental hypoxia could potentiate the effects of exercise training on glucose metabolism and insulin sensitivity. METHODS:Fourteen adolescents with obesity were assigned to 6 wk of exercise training either in normoxic or in hypoxic conditions (FiO2 15%). Adolescents traine...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000001694
更新日期:2018-11-01 00:00:00
abstract::The inheritance of cardiac changes during acute dynamic physical exercise was studied in 21 pairs of monozygotic and 12 pairs of dizygotic male twins, ages 18-31 yr. Echocardiography was performed in resting conditions and at submaximal supine bicycle exercise at a heart rate of 110 bpm. In resting conditions signific...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1991-11-01 00:00:00
abstract::The purpose of the study was to evaluate selected parameters describing performance characteristics of a free-weight and isokinetic bench press. A secondary purpose was an attempt to clarify the technique requirements essential for a successful lift. Parameters describing the free-weight condition were generated from ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1985-06-01 00:00:00
abstract:PURPOSE:The benefits from physical activity (PA) and cardiorespiratory fitness (CRF) on normal age-related cognitive decline might be sex-dependent. Our aim was to explore the relationship between different types of PA, CRF and cognition and to identify the mediating effects of CRF in the association between PA and cog...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002570
更新日期:2020-12-23 00:00:00
abstract:PURPOSE:This study examined the relationship between age and gender with physical activity (PA) and how meeting of PA guidelines (PAGL) is related to socioeconomic status (SES) and sedentary behaviors (SB). METHODS:Data were collected from 11-, 13-, and 15-yr-old students in 32 countries participating in the Health Be...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3181917722
更新日期:2009-04-01 00:00:00
abstract::The purposes of this study were to evaluate (a) the effects of step rate and upper body support on the VO2 and HR responses to fixed work rates on the StairMaster 4000 (SM), (b) the accuracy of the SM settings, and (c) how HR compared with that measured during grade-walking on a treadmill. Six subjects worked at a slo...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1992-09-01 00:00:00
abstract::Recently, Sarna et al. (Med. Sci. Sports Exerc. 25:237-244, 1993) reported increased mean life expectancy in former world class athletes. Because lifestyle is associated with longevity, we have examined whether health habits of former Finnish male athletes (N = 1274; present mean age: 57.5, range: 36-94 yr) differed f...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/00005768-199402000-00013
更新日期:1994-02-01 00:00:00
abstract:UNLABELLED:Magnesium (Mg) is important for regulating ion transport and cellular metabolism in all body tissues. In skeletal muscle Mg is involved in the neuromuscular activity, excitation, and muscle contraction. Mg deficiency can cause muscle weakness and muscle cramps. Less than 1% of total body Mg is found in serum...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00005768-199811000-00005
更新日期:1998-11-01 00:00:00
abstract:PURPOSE:To comprehensively quantify through daily, serial measures changes in knee laxity as a function of changing sex-hormone levels across one complete menstrual cycle. METHODS:Twenty-five females, 18 - 30 yr, body mass index < or = 30, who reported normal menstrual cycles (28-32 d) over the past 6 months participa...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000132270.43579.1a
更新日期:2004-07-01 00:00:00
abstract:PURPOSE:Text books attribute the side pain "stitch" during exercise to changes in blood flow to the viscera, but the little available research favors stretching of visceral ligaments. We therefore induced and modified stitch experimentally to investigate its cause and possible treatments. METHODS:Ten active healthy yo...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00005768-199908000-00014
更新日期:1999-08-01 00:00:00
abstract:PURPOSE:The objective of this study is to determine whether childhood muscular fitness phenotypes (strength, endurance, and power) are independently associated with adult metabolic syndrome (MetS). METHODS:We conducted a longitudinal study including 737 participants who had muscular fitness measures in 1985 when age 9...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000955
更新日期:2016-09-01 00:00:00
abstract:INTRODUCTION:Muscle force production is usually impaired in people with spinal cord injury (SCI). The use of high-intensity neuromuscular electrical stimulation (NMES) strength training can help promote metabolically active lean muscle mass and, thus, increase muscle mass and improve physical health and quality of life...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001637
更新日期:2018-09-01 00:00:00
abstract:PURPOSE:The effect of quantified resistance and high impact exercise training on bone mass as modified by age and oral contraceptive (OCont) use in young women was studied. METHODS:Women were categorized by age (18-23 vs 24-31 yr) and OCont use, and were then randomized into either three sessions of resistance exercis...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00005768-200106000-00004
更新日期:2001-06-01 00:00:00
abstract:PURPOSE:Maximizing carbohydrate availability is important for many endurance events. Combining pectin and sodium alginate with ingested maltodextrin-fructose (MAL + FRU + PEC + ALG) has been suggested to enhance carbohydrate delivery via hydrogel formation, but the influence on exogenous carbohydrate oxidation remains ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000002262
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:The purpose of this study was to investigate the physiological and performance responses to a simulated freestyle wrestling tournament after typical weight loss techniques used by amateur wrestlers. METHODS:Twelve Division I collegiate wrestlers (mean +/- SD;19.33 +/- 1.16 yr) lost 6% of total body weight duri...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200108000-00019
更新日期:2001-08-01 00:00:00
abstract:INTRODUCTION:Different therapies can improve clinical and motor symptoms of multiple sclerosis (MS) similarly, but studies comparing the effects of different exercise therapies on clinical and motor outcomes are scant. We compared the effects of exergaming (EXE), balance (BAL), cycling (CYC), proprioceptive neuromuscul...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000002228
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:To validate the 7-d Physical Activity Recall (PAR) telephone interview version and its activity intensity categories. METHODS:Seventy-four adults (47 women, 27 men), ranging in age (18-67) and activity levels, were interviewed by phone and in-person using the same PAR protocol. Each participant wore a TriTrac-...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.MSS.0000064941.43869.4E
更新日期:2003-05-01 00:00:00
abstract::To study effort tolerance in elderly women with different physical activity backgrounds, 52 physically active (PA) and 42 sedentary control women (CO) aged 66-85 yr were assigned to perform cycle ergometer exercise to their volitional maximum. Oxygen uptake, respiratory exchange ratio (RER), heart rate, work power, an...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199801000-00024
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:Cross-sectional studies suggest that training can increase muscle carnosine (MCarn), although longitudinal studies have failed to confirm this. A lack of control for dietary β-alanine intake or muscle fiber type shifting may have hampered their conclusions. The purpose of the present study was to investigate th...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000001697
更新日期:2018-11-01 00:00:00
abstract:PURPOSE:The purpose of this study is to compare the time-frequency characteristic, using nonlinearly scaled wavelets, of the EMG signal as well as the three-dimensional (3D) knee kinematics of female and male elite soccer players performing an unanticipated cutting maneuver. METHODS:Fifteen female and 15 male elite so...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e31817b8e9e
更新日期:2008-10-01 00:00:00
abstract:PURPOSE:This study aimed to quantify the frequency, magnitude, and location of head impacts sustained by male and female collegiate ice hockey players during two seasons of play. METHODS:During two seasons, 88 collegiate athletes (51 females, 37 males) on two female and male National Collegiate Athletic Association va...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e31822b0ab4
更新日期:2012-02-01 00:00:00
abstract:PURPOSE:To investigate the maximal physiological responses between aquatic and land-based graded exercise tests in overweight women. METHODS:Twenty healthy, overweight (body mass index (BMI) > or = 25 kg.m(-2)), Caucasian women (mean +/- SD; age 48 +/- 7 yr, BMI 30 +/- 4 kg.m(-2)) completed a deep water running (DWR) ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e318164d0e0
更新日期:2008-05-01 00:00:00
abstract::The ventilatory threshold (VT) has been suggested as a method for determining exercise training intensity in cardiac transplant patients (CTPs). Since the VT has not been validated against the more accepted marker of the anaerobic threshold, the lactate threshold (LT), in CTPs, the purpose of this investigation was to...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:
更新日期:1993-02-01 00:00:00
abstract::Eight older (52 to 62 yr old) post-menopausal and 8 younger (20 to 30 yr old) women were matched with respect to body size, fatness, and maximal oxygen consumption, heat-acclimated, and then exercised at 35 to 40% maximal oxygen consumption in a warm-humid (37 degrees C, 60% relative humidity) environment. Results wer...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/00005768-198820020-00009
更新日期:1988-04-01 00:00:00
abstract:PURPOSE:Aerodynamic drag plays an important role in performance for athletes practicing sports that involve high-velocity motions. In giant slalom, the skier is continuously changing his/her body posture, and this affects the energy dissipated in aerodynamic drag. It is therefore important to quantify this energy to un...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3182443315
更新日期:2012-06-01 00:00:00
abstract::A 25-yr-old female triathlete presented with 4 d of increasing left calf pain that started 1 d after an elective termination of pregnancy during the eighth week of gestation. She had been training with running, bicycling, and swimming but did not recall any injury to the calf muscle. Deep venous thrombosis of the calf...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:PURPOSE:This study established the published prediction equations for the energy expenditure of walking and running compared with the measured values. To make this comparison we first determined whether differences exist in energy expenditure for 1600 m of walking versus running, and whether energy expenditure differen...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000147584.87788.0e
更新日期:2004-12-01 00:00:00