Hemoglobin F in myelodysplastic syndrome.

abstract：:A 64-year-old woman with adult T cell leukemia (ATL) was admitted to our hospital with severe hypercalcemia. The serum calcium level was elevated to 14.9 mg/dl. Biochemical parameters for bone formation including serum osteocalcin (bone Gla protein, BGP) and alkaline phosphatase (ALP) were normal. The serum levels of ...

journal_title：Annals of hematology

authors： Hino M,Yamane T,Ohta K,Shioi A,Koyama H,Tahara H,Nishizawa Y,Tatsumi N

更新日期：2001-07-01 00:00:00

abstract：:We investigated a new protein-C (PC) concentrate in a child with a type-II homozygous deficiency, concerning tolerance and safety. By means of various functional and antigen assays the in vivo recovery and the half-life were determined. In order to compare the results we reduced the measured values to the average half...

journal_title：Annals of hematology

authors： Auberger K

更新日期：1992-03-01 00:00:00

abstract：:Sickle cell disease (SCD) is a relatively common inherited hemolytic anemia among individuals of African descent. Genetic factors might clarify clinical diversity of the disease and variations in treatment response. Some researchers investigated heme oxygenase-1 (HMOX1) or chemokine receptor 5 (CCR5Δ32) genotypes amon...

journal_title：Annals of hematology

authors： Bakr S,Khorshied M,Talha N,Jaffer KY,Soliman N,Eid K,El-Ghamrawy M

更新日期：2019-08-01 00:00:00

abstract：:We have established reference values of peripheral blood lymphocyte subsets in healthy female Wistar rats under highly standardized conditions. Using monoclonal antibodies and flow cytometry, T lymphocytes (OX19+), B lymphocytes (OX6+ and anti-Ig+), T-helper/inducer (W3/25+), and T-suppressor/cytotoxic subsets (OX8+) ...

journal_title：Annals of hematology

authors： Franch A,Castellote C,Pelegrí C,Tolosa E,Castell M

更新日期：1993-09-01 00:00:00

abstract：:Previous studies have suggested that adherence to imatinib therapy can be an obstacle among patients with chronic myeloid leukemia (CML). We studied adherence to imatinib therapy among CML patients treated at the Sahlgrenska University Hospital. We identified all CML patients that were alive at the 1st of January 2010...

journal_title：Annals of hematology

authors： Jönsson S,Olsson B,Söderberg J,Wadenvik H

更新日期：2012-05-01 00:00:00

abstract：:Patients with non-Hodgkin's lymphoma (NHL) receiving rituximab-containing chemotherapy are at risk of developing respiratory complications, but comprehensive information on these complications and their impact on survival is lacking. We performed a retrospective cohort analysis on 123 NHL patients who received rituxim...

journal_title：Annals of hematology

authors： Keefer K,Bender R,Liao J,Sivik J,Van de Louw A

更新日期：2018-12-01 00:00:00

abstract：:Although eosinophilia has been reported as a side effect of purine analogues, there is no report on fludarabine-induced eosinophilia in chronic lymphocytic leukemia (CLL). During chemotherapy with fludarabine and cyclophosphamide, we observed two cases of significant eosinophilia. A 67-year-old patient with CLL develo...

journal_title：Annals of hematology

authors： Sezer O,Schmid P,Hallek M,Schweigert M,Beinert T,Langelotz C,Mergenthaler HG,Possinger K

更新日期：1999-10-01 00:00:00

abstract：:We evaluated the clinical features, treatment modalities, treatment responses, and prognosis of our patients with immune thrombocytopenia (ITP). Furthermore, we estimated the frequency of ITP in the Thrace region of Turkey. Two hundred sixteen patients diagnosed with ITP between 2000 and 2012 at our center were retros...

journal_title：Annals of hematology

authors： Koylu A,Pamuk GE,Uyanik MS,Demir M,Pamuk ON

更新日期：2015-03-01 00:00:00

abstract：:High-dose chemotherapy (HDT) and stem cell transplantation is a newer treatment option widely applied in poor-risk germ cell tumor patients. Due to the increasing practical clinical experience and the availability of hematopoietic growth factors, this treatment approach has become a relatively safe procedure. Dependin...

journal_title：Annals of hematology

authors： Siegert W,Rick O,Beyer J

更新日期：1998-05-01 00:00:00

abstract：:We present a patient with chronic myelomonocytic leukemia who showed disseminated papules and nodules. Arguments in favor of leukemia cutis are the clinical appearance, the cyclic pattern with which the lesions appeared and disappeared, and the histologic features. The lesions reproducibly responded to treatment with ...

journal_title：Annals of hematology

authors： Wintzen M,Kluin PM,den Ottolander GJ

更新日期：2000-07-01 00:00:00

abstract：:The aim of the present study was to investigate the prevalence of chronic idiopathic neutropenia of adults (CINA) among an apparently healthy population born and living on the island of Crete. The study was carried out with 778 subjects, 392 men aged 16-78 years (median 43 years) and 386 women aged 15-79 years (median...

journal_title：Annals of hematology

authors： Papadaki HA,Xylouri I,Coulocheri S,Kalmanti M,Kafatos A,Eliopoulos GD

更新日期：1999-07-01 00:00:00

abstract：:Overproduction of proinflammatory cytokines is characteristic of hemophagocytic syndrome (HPS), a highly lethal inflammatory disease. Peripheral blood monocytes include two distinct subpopulations according to surface antigen expression: a major type, CD14(+)/CD16(-) (classical monocytes), and a minor type, CD14(+)/CD...

journal_title：Annals of hematology

authors： Takeyama N,Yabuki T,Kumagai T,Takagi S,Takamoto S,Noguchi H

更新日期：2007-11-01 00:00:00

abstract：:Several revisions of International Prognostic Index (IPI) have been proposed for patients with diffuse large B-cell lymphoma (DLBCL) after the introduction of rituximab. Expanding evidence suggests that baseline absolute lymphocyte count (ALC) is also an independent factor for outcome prediction. We investigated the o...

journal_title：Annals of hematology

authors： Huang YC,Liu CY,Lu HJ,Liu HT,Hung MH,Hong YC,Hsiao LT,Gau JP,Liu JH,Hsu HC,Chiou TJ,Chen PM,Tzeng CH,Yu YB

更新日期：2013-11-01 00:00:00

abstract：:To gain insight into the natural history of cytomegalovirus (CMV) infection following unrelated cord blood transplantation (UCBT) in seropositive patients, we analyzed the data of 349 seropositive patients who received UCBT in Korea between 2000 and 2011. CMV reactivation occurred in 49 % (171/349) of the CMV-seroposi...

journal_title：Annals of hematology

authors： Park M,Lee YH,Lee SH,Yoo KH,Sung KW,Koo HH,Lee JW,Kang HJ,Park KD,Shin HY,Ahn HS,Lee JW,Chung NG,Cho B,Kim HK,Koh KN,Im HJ,Seo JJ,Baek HJ,Kook H,Hwang TJ,Lee JM,Hah JO,Lim YJ,Park JE,Lyu CJ,Lim YT,Ch

更新日期：2015-03-01 00:00:00

abstract：:Vitamin K2 induces differentiation of leukemic cell lines and apoptosis of immature blasts in myelodysplastic syndrome (MDS). We recently reported a case of MDS-refractory anemia (MDS-RA) with trilineage hematologic response to oral administration of menatetrenone, a vitamin K2 analog. To determine a possible role of ...

journal_title：Annals of hematology

authors： Takami A,Asakura H,Nakao S

更新日期：2002-01-01 00:00:00

abstract：:Juvenile myelomonocytic leukemia (JMML) is a rare hematologic malignancy in children. Hyperactivation of the Ras pathway from gene mutations is known to be the key culprit in the development of JMML. In this study, we investigated Ras pathway mutations and prognostic implication in Korean patients with JMML. A total o...

journal_title：Annals of hematology

authors： Park HD,Lee SH,Sung KW,Koo HH,Jung NG,Cho B,Kim HK,Park IA,Lee KO,Ki CS,Kim SH,Yoo KH,Kim HJ

更新日期：2012-04-01 00:00:00

abstract：:Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hemolytic disease with thrombosis as a major complication. The mechanism of thrombosis and related risk factors in PNH patients are still not well characterized. We retrospectively enrolled 99 patients with newly diagnosed PNH at our institute from 2011 to 2016....

journal_title：Annals of hematology

authors： Huang Y,Liu X,Chen F,Zhou W,Li H,Long Z,Yang C,Chen M,Han B

更新日期：2019-10-01 00:00:00

abstract：:In 1989, a prospective randomized multicenter study was initiated in order to determine the safety and efficacy of oral clodronate in myeloma patients. The primary objective of this long-term trial is to evaluate whether supportive clodronate is able to prevent or retard the progression of bone disease and reduce the ...

journal_title：Annals of hematology

authors： Clemens MR,Fessele K,Heim ME

更新日期：1993-03-01 00:00:00

abstract：:Immunoglobulin D (IgD) myeloma is a rare subtype that used to lead to a poor outcome. To investigate the current clinical features, cytogenetic changes and survival of patients with IgD myeloma under novel treatments, we analysed 47 patients with IgD myeloma, 31 men and 16 women, with a median age of 54.5 years. We fo...

journal_title：Annals of hematology

authors： Chen L,Fan F,Deng J,Xu J,Xu A,Sun C,Hu Y

更新日期：2019-04-01 00:00:00

abstract：:Second allogeneic hematopoietic stem cell transplantation (allo-HSCT) has a low survival outcome and a high non-relapse mortality (NRM) rate which is a major obstacle to this treatment. We hypothesized that the status of malnourishment after first allo-HSCT as represented by the geriatric nutritional risk index (GNRI)...

journal_title：Annals of hematology

authors： Kaito S,Wada A,Adachi H,Konuma R,Kishida Y,Nagata A,Konishi T,Yamada Y,Kumagai T,Yoshifuji K,Mukae J,Akiyama M,Inamoto K,Toya T,Igarashi A,Najima Y,Muto H,Kobayashi T,Kakihana K,Ohashi K,Sakamaki H,Doki N

更新日期：2020-07-01 00:00:00

abstract：:As ethnic variations are known to exist in inherited genetic defects, the clinico-haematological profile of Indian children with thrombophilia may be different from that of Caucasians. The aim of the study was to analyse the phenotypic and genotypic causes of thrombophilia in Indian children. Forty patients with arter...

journal_title：Annals of hematology

authors： Gupta PK,Ahmed RP,Bhattacharyya M,Kannan M,Biswas A,Kalra V,Saxena R

更新日期：2005-02-01 00:00:00

abstract：:Since December 2019, a novel coronavirus has spread throughout China and across the world, causing a continuous increase in confirmed cases within a short period of time. Some studies reported cases of thrombocytopenia, but hardly any studies mentioned how the virus causes thrombocytopenia. We propose several mechanis...

journal_title：Annals of hematology

authors： Xu P,Zhou Q,Xu J

更新日期：2020-06-01 00:00:00

abstract：:Interstitial pneumonia (IP) is a lethal complication in lymphoma patients undergoing chemotherapy. A total of 2212 consecutive patients diagnosed with lymphoma between 2009 and 2014 were enrolled in the present study. IP was defined as diffuse pulmonary interstitial infiltrate found on computed tomography scans. IP wa...

journal_title：Annals of hematology

authors： Liu WP,Wang XP,Zheng W,Xie Y,Tu MF,Lin NJ,Ping LY,Ying ZT,Zhang C,Deng LJ,Ding N,Wang XG,Song YQ,Zhu J

更新日期：2018-01-01 00:00:00

abstract：:In the present study, we questioned whether the cholesterol synthesis inhibitor lovastatin potentiates the cytotoxicity of chemotherapeutic agents in the primitive CD34(+) subpopulation of acute myeloid leukemia (AML) cells. AML mononuclear cells (n = 17) were sorted in CD34(+) and CD34(-) fractions and compared to no...

journal_title：Annals of hematology

authors： de Jonge-Peeters SD,van der Weide K,Kuipers F,Sluiter WJ,de Vries EG,Vellenga E

更新日期：2009-06-01 00:00:00

abstract：:We screened for increased osmotic fragility of erythrocytes in 1464 healthy German blood donors. The osmotic fragility was determined by an acidified glycerol lysis test (AGLT) using glycerol-sodium phosphate-buffered NaCl solution. Since the original test described by Zanella et al. [23] showed only low specificity f...

journal_title：Annals of hematology

authors： Eber SW,Pekrun A,Neufeldt A,Schröter W

更新日期：1992-02-01 00:00:00

abstract：:Sickle cell patients are characterized by stress erythropoiesis involving cytokines, growth factors, and adhesion molecules. We set out to determine whether serum soluble vascular cell adhesion molecule-1 (sVCAM-1) levels, which are inversely related to red blood cell counts in sickle cell disease (SCD), reflect eryth...

journal_title：Annals of hematology

authors： Duits AJ,Rojer RA,van Endt T,MacGillavry MR,ten Cate H,Brandjes DP,Schnog JB

更新日期：2003-03-01 00:00:00

abstract：:Anaphylactoid reaction to cyclophosphamide administration in a 85-year old woman is described. Symptomatology was restricted to bronchospasm, which regressed within one hour. This incomplete and rapidly regressive symptomatology might be explained by previous administration of methylprednisolone. No anaphylactoid symp...

journal_title：Annals of hematology

authors： Salles G,Vial T,Archimbaud E

更新日期：1991-02-01 00:00:00

abstract：:Increasing the number of megakaryocytic cells in stem cell transplants by ex vivo expansion culture may provide an approach to accelerate platelet engraftment after high-dose chemotherapy. However, it is unknown if a relationship exists between the expansion potential of progenitor cells and the time to platelet engra...

journal_title：Annals of hematology

authors： Drayer AL,Smit Sibinga CT,Esselink MT,de Wolf JT,Vellenga E

更新日期：2002-04-01 00:00:00

abstract：:Azacitidine (AZA) is a DNA hypomethylation agent administered in myeloid neoplasms; however, there is still a lack of established predictors of response. We studied 113 patients with myelodysplastic syndromes (n = 85) or acute myeloid leukemia (n = 28) who received AZA to assess the predictive value on response of cli...

journal_title：Annals of hematology

authors： Martín I,Navarro B,Serrano A,Villamón E,Calabuig M,Solano C,Chaves FJ,Yagüe N,Orts M,Amat P,Fuentes A,Seda E,García F,Hernández-Boluda JC,Tormo M

更新日期：2020-03-01 00:00:00

abstract：:The BCR/ABL1 fusion gene is mainly caused by the t(9; 22)(q34; q11.2) translocation, which results in the Philadelphia (Ph) chromosome. The Ph chromosome is the typical hallmark in chronic myeloid leukemia (CML), but can also be present in acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). The BCR/AB...

journal_title：Annals of hematology

authors： Pelz AF,Kröning H,Franke A,Wieacker P,Stumm M

更新日期：2002-03-01 00:00:00