Specific cutaneous infiltrate caused by Staphylococcus aureus in a patient with chronic myelomonocytic leukemia.

Abstract:

:We present a patient with chronic myelomonocytic leukemia who showed disseminated papules and nodules. Arguments in favor of leukemia cutis are the clinical appearance, the cyclic pattern with which the lesions appeared and disappeared, and the histologic features. The lesions reproducibly responded to treatment with antibiotics given for a Staphylococcus aureus infection. We speculate that at least in some patients, leukemic cells are recruited in the skin because of local infection and do not merely reflect autonomous growth but an inflammatory response.

journal_name

Ann Hematol

journal_title

Annals of hematology

authors

Wintzen M,Kluin PM,den Ottolander GJ

doi

10.1007/s002770000156

subject

Has Abstract

pub_date

2000-07-01 00:00:00

pages

402-4

issue

7

eissn

0939-5555

issn

1432-0584

journal_volume

79

pub_type

杂志文章
  • Second line azacitidine for elderly or infirmed patients with acute myeloid leukemia (AML) not eligible for allogeneic hematopoietic cell transplantation-a retrospective national multicenter study.

    abstract::Elderly and infirm patients with acute myeloid leukemia (AML) with either induction refractory or relapse disease may benefit from treatment with azacitidine. We retrospectively reviewed the data from five tertiary centers in Israel, treated between 2009 and 2015. Thirty-four patients (median age 74 years) were identi...

    journal_title:Annals of hematology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00277-016-2914-5

    authors: Ram R,Gatt M,Merkel D,Helman I,Inbar T,Nagler A,Avivi I,Ofran Y

    更新日期:2017-04-01 00:00:00

  • Multiple myeloma in elderly patients-a Portuguese multicentric real-life study.

    abstract::Patients older than 75 years old with multiple myeloma (MM) have shorter survival and are usually treated differently from what features in clinical trials. In this study, the authors characterized the Portuguese population of MM patients above 75 years old, treated between 2009 and 2016. We compared the outcomes obta...

    journal_title:Annals of hematology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1007/s00277-019-03640-y

    authors: João C,Bergantim R,Neves M,Chacim S,Afonso C,Barradas J,Bernardo M,Coelho H,Esteves G,Fraga C,Geraldes C,Gonçalves C,Jorge A,Macedo A,Mendonça T,Moreira A,Roque A,Sarmento AB,Trigo F,Vitória H,Esteves S,Lúcio P

    更新日期:2019-07-01 00:00:00

  • Inhibition of monocyte and polymorphonuclear granulocyte immune phagocytosis by monoclonal antibodies specific for Fc gamma RI, II and III.

    abstract::We tested two Fc gamma receptor I (Fc gamma RI); six Fc gamma RII; and six Fc gamma RIII-specific monoclonal antibodies (mAb) for their capacity to inhibit monocyte and polymorphonuclear granulocyte (PMN) immune phagocytosis which is mediated by Fc gamma R. We used human red blood cells (rbc) coated with hIgG1 or mIgG...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s002770050249

    authors: Flesch BK,Achtert G,Neppert J

    更新日期:1997-01-01 00:00:00

  • Positron emission tomography in the staging of patients with Hodgkin's lymphoma. A prospective multicentric study by the Intergruppo Italiano Linfomi.

    abstract::In this prospective multicentric study, we investigated the contribution of positron emission tomography (PET) scanning to the staging of Hodgkin's lymphoma (HL) by computed tomography (CT) and attempted to determine whether it has any impact on therapeutic approach. One hundred eighty six consecutive patients with HL...

    journal_title:Annals of hematology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00277-007-0356-9

    authors: Rigacci L,Vitolo U,Nassi L,Merli F,Gallamini A,Pregno P,Alvarez I,Salvi F,Sancetta R,Castagnoli A,Versari A,Biggi A,Gregianin M,Pelosi E,Chisesi T,Bosi A,Levis A,Intergruppo Italiano Linfomi.

    更新日期:2007-12-01 00:00:00

  • Intermediate intensity conditioning regimen containing FLAMSA, treosulfan, cyclophosphamide, and ATG for allogeneic stem cell transplantation in elderly patients with relapsed or high-risk acute myeloid leukemia.

    abstract::Lower dosage of total body irradiation (TBI) and chemotherapy in reduced-intensity conditioning (RIC) regimens prior to allogeneic stem cell transplantation have reduced the toxicity of the conditioning and non-relapse mortality. The FLAMSA-RIC protocol for high-risk patients with acute myeloid leukemia (AML) and myel...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s00277-011-1253-9

    authors: Chemnitz JM,von Lilienfeld-Toal M,Holtick U,Theurich S,Shimabukuro-Vornhagen A,Krause A,Brossart P,Hallek M,Scheid C

    更新日期:2012-01-01 00:00:00

  • Lymphoma-associated hemophagocytic lymphohistiocytosis: experience in adults from a single institution.

    abstract::Lymphoma-associated hemophagocytic lymphohistiocytosis (HLH) is a rare but fatal disease. Differences between B cell and T cell lymphoma-associated HLH remain unclear, specifically clinical characteristics and survival. We retrospectively analyzed 30 lymphoma-associated HLH patients from July 2004 to October 2012. Pat...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s00277-013-1784-3

    authors: Yu JT,Wang CY,Yang Y,Wang RC,Chang KH,Hwang WL,Teng CL

    更新日期:2013-11-01 00:00:00

  • Radiotherapy and PGEMOX/GELOX regimen improved prognosis in elderly patients with early-stage extranodal NK/T-cell lymphoma.

    abstract::The optimal treatment strategy for elderly patients with natural killer/T-cell lymphoma (NKTCL) remains to be established. A total of 63 elderly patients with newly diagnosed NKTCL were retrospectively reviewed. Among the patients with stage I-II disease, 58.3 % received radiotherapy (RT) ± chemotherapy, and 41.7 % re...

    journal_title:Annals of hematology

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00277-015-2395-y

    authors: Bi XW,Xia Y,Zhang WW,Sun P,Liu PP,Wang Y,Huang JJ,Jiang WQ,Li ZM

    更新日期:2015-09-01 00:00:00

  • Geriatric nutritional risk index as a useful prognostic factor in second allogeneic hematopoietic stem cell transplantation.

    abstract::Second allogeneic hematopoietic stem cell transplantation (allo-HSCT) has a low survival outcome and a high non-relapse mortality (NRM) rate which is a major obstacle to this treatment. We hypothesized that the status of malnourishment after first allo-HSCT as represented by the geriatric nutritional risk index (GNRI)...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s00277-020-04089-0

    authors: Kaito S,Wada A,Adachi H,Konuma R,Kishida Y,Nagata A,Konishi T,Yamada Y,Kumagai T,Yoshifuji K,Mukae J,Akiyama M,Inamoto K,Toya T,Igarashi A,Najima Y,Muto H,Kobayashi T,Kakihana K,Ohashi K,Sakamaki H,Doki N

    更新日期:2020-07-01 00:00:00

  • Regulation of FLT3 and its ligand in normal hematopoietic progenitor cells.

    abstract::FLT3 and its ligand (FL) are one of the regulators of normal hematopoiesis. Ligand-independent activation of FLT3 occurs in about 30% of acute myeloid leukemia cases and is one goal for selectively targeted therapies. However, the function of FLT3/FL in the regulation of non-malignant immature hematopoietic cells is p...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s00277-008-0605-6

    authors: Weisel KC,Yildirim S,Schweikle E,Kanz L,Möhle R

    更新日期:2009-03-01 00:00:00

  • Prognostic value of interim and end-of-treatment FDG-PET in follicular lymphoma: a systematic review.

    abstract::This study aimed to systematically review the prognostic value of interim and end-of-treatment (18)F-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) in follicular lymphoma during and after first-line therapy. The PubMed/MEDLINE database was searched for relevant original studies. Included studies were ...

    journal_title:Annals of hematology

    pub_type: 杂志文章,评审

    doi:10.1007/s00277-015-2553-2

    authors: Adams HJA,Nievelstein RAJ,Kwee TC

    更新日期:2016-01-01 00:00:00

  • Secondary central nervous system (CNS) involvement in patients with diffuse large B-cell lymphoma: a therapeutic dilemma.

    abstract::Secondary central nervous system (CNS) involvement in diffuse large B-cell lymphoma (DLBCL) includes an isolated CNS relapse or CNS involvement with systemic disease progression. This rare but fatal clinical problem still remains a therapeutic dilemma in the management of DLBCL. However, there are limited data about i...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s00277-010-1104-0

    authors: Kim SJ,Oh SY,Kim JS,Kim H,Lee GW,Won JH,Shin HJ,Yang DH,Choi CW,Park J,Kim WS,Suh C

    更新日期:2011-05-01 00:00:00

  • Morphologic and phenotypic changes of the leukemic cells in a case of marginal zone B-cell lymphoma.

    abstract::A particular case of marginal zone B-cell lymphoma (MZBCL) presenting with leukemic lymphocytes is reported. In the present observation, the leukemic cells not only displayed a remarkable morphological fluctuation but also had an unusual phenotype, changing with time. These phenotypic features, which have been functio...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s002770050274

    authors: Dargent JL,Delville JP,Kornreich A,Pradier O,Cochaux P,Velu T,Capel P,Feremans W,Neve P

    更新日期:1997-03-01 00:00:00

  • Meningeal and cerebral involvement in multiple myeloma patients.

    abstract::Cerebral involvement is an unusual complication in multiple myeloma: herein four patients who presented myelomatous meningitis with multiple intraparenchymal lesions or a localized cerebral plasmacytoma are described. Two of these patients relapsed with meningeal involvement and a very limited disease outside the cent...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s00277-001-0387-6

    authors: Patriarca F,Zaja F,Silvestri F,Sperotto A,Scalise A,Gigli G,Fanin R

    更新日期:2001-12-01 00:00:00

  • Distinct clinical and biological characteristics of acute myeloid leukemia with higher expression of long noncoding RNA KIAA0125.

    abstract::Expression of long non-coding RNA KIAA0125 has been incorporated in various gene expression signatures for prognostic prediction in acute myeloid leukemia (AML) patients, yet its functions and clinical significance remain unclear. This study aimed to investigate the clinical and biological characteristics of AML beari...

    journal_title:Annals of hematology

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00277-020-04358-y

    authors: Wang YH,Lin CC,Hsu CL,Hung SY,Yao CY,Lee SH,Tsai CH,Hou HA,Chou WC,Tien HF

    更新日期:2021-02-01 00:00:00

  • A human Burkitt's lymphoma cell line carrying t(8;22) and t(14;18) translocations.

    abstract::A combination of chromosomal translocations associated with bcl-2 re-arrangement (t(14;18)) and c-myc re-arrangement (t(8;14), t(8;22), or t(2;8)) is a rare event. We describe the first cell line exhibiting t(14;18) and t(8;22), which will enable us to study the interactions of bcl-2 and c-myc systematically. Cell cul...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s00277-007-0313-7

    authors: Kiefer T,Schüler F,Knopp A,Wimmer M,Hirt C,Schaefer HE,Dölken G

    更新日期:2007-11-01 00:00:00

  • Immune thrombocytopenia: epidemiological and clinical features of 216 patients in northwestern Turkey.

    abstract::We evaluated the clinical features, treatment modalities, treatment responses, and prognosis of our patients with immune thrombocytopenia (ITP). Furthermore, we estimated the frequency of ITP in the Thrace region of Turkey. Two hundred sixteen patients diagnosed with ITP between 2000 and 2012 at our center were retros...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s00277-014-2220-z

    authors: Koylu A,Pamuk GE,Uyanik MS,Demir M,Pamuk ON

    更新日期:2015-03-01 00:00:00

  • Concepts in immuno-oncology: tackling B cell malignancies with CD19-directed bispecific T cell engager therapies.

    abstract::The B cell surface antigen CD19 is a target for treating B cell malignancies, such as B cell precursor acute lymphoblastic leukemia and B cell non-Hodgkin lymphoma. The BiTE® immuno-oncology platform includes blinatumomab, which is approved for relapsed/refractory B cell precursor acute lymphoblastic leukemia and B ce...

    journal_title:Annals of hematology

    pub_type: 杂志文章,评审

    doi:10.1007/s00277-020-04221-0

    authors: Viardot A,Locatelli F,Stieglmaier J,Zaman F,Jabbour E

    更新日期:2020-10-01 00:00:00

  • Changes in bone marrow morphology in adults receiving romiplostim for the treatment of thrombocytopenia associated with primary immune thrombocytopenia.

    abstract::The effects of romiplostim on bone marrow morphology were evaluated in adults with immune thrombocytopenia (ITP). Patients with platelet counts <50 × 10(9)/L, ≥1 prior ITP therapies, and no collagen at baseline received weekly subcutaneous romiplostim starting at 1 μg/kg, adjusted to maintain platelet counts between 5...

    journal_title:Annals of hematology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00277-016-2682-2

    authors: Janssens A,Rodeghiero F,Anderson D,Chong BH,Boda Z,Pabinger I,Červinek L,Terrell DR,Wang X,Franklin J

    更新日期:2016-06-01 00:00:00

  • Stroke prevention in the young child with sickle cell anaemia.

    abstract::Cerebrovascular disease resulting in stroke is a serious and preventable complication of sickle cell anaemia (SCA). Children at high risk of preventable stroke can be identified by transcranial Doppler ultrasound (TCD). Current guidelines in the UK recommend annual TCD screening from 3 years, although studies suggest ...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s00277-009-0757-z

    authors: Roberts L,O'Driscoll S,Dick MC,Height SE,Deane C,Goss DE,Pohl K,Rees DC

    更新日期:2009-10-01 00:00:00

  • Immune thrombocytopenia and Fc receptor-mediated phagocyte function.

    abstract::The response to intravenous immunoglobulin treatment (IVIG) is thought, in part, to be due to blockade of Fc receptor for IgG in the mononuclear phagocyte system (MPS). We have studied this by measuring splenic clearance of heat-damaged and IgG antibody-coated red cells in immune thrombocytopenic patients receiving IV...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/BF01698483

    authors: Newland AC,Macey MG

    更新日期:1994-08-01 00:00:00

  • Rituximab in the treatment of idiopathic thrombocytopenic purpura (ITP).

    abstract::The objective of this study was to evaluate the efficacy and safety of rituximab in the treatment of patients with idiopathic thrombocytopenic purpura (ITP). A prospective study was performed at Mubarak Al-Kabeer University Hospital involving the use of rituximab in 14 patients who had previously been treated with ste...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s00277-008-0574-9

    authors: Alasfoor K,Alrasheed M,Alsayegh F,Mousa SA

    更新日期:2009-03-01 00:00:00

  • Can prognostic scoring systems for chronic myeloid leukemia as established in adults be applied to pediatric patients?

    abstract::In contrast to adult medicine, specific scoring systems predicting the treatment response for an individual pediatric patient (pt) with chronic myeloid leukemia (CML) have not yet been defined. We evaluated to what extend prognostic scores as described for adults (e.g., Sokal, Hasford, EUTOS score) resulted in compara...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s00277-015-2367-2

    authors: Gurrea Salas D,Glauche I,Tauer JT,Thiede C,Suttorp M

    更新日期:2015-08-01 00:00:00

  • Subcutaneous panniculitis-like T-cell lymphoma: complete remission with fludarabine.

    abstract::Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is an uncommon type of cutaneous lymphoma with an aggressive natural history. It generally carries a poor prognosis despite standard anthracycline-based chemotherapy. The optimum therapy is unknown. We report the case of a 66-year-old man with CD4/CD8 double negat...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s00277-003-0638-9

    authors: Go RS,Gazelka H,Hogan JD,Wester SM

    更新日期:2003-04-01 00:00:00

  • Multiple myeloma in younger patients: the role of age as prognostic factor.

    abstract::The presenting features of 356 previously untreated multiple myeloma (MM) patients grouped according to age were analyzed in order (a) to elucidate the possible differences in initial clinical and laboratory features between patients younger than 50 years and the older ones and (b) to statistically assess the prognost...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s002770050365

    authors: Corso A,Klersy C,Lazzarino M,Bernasconi C

    更新日期:1998-02-01 00:00:00

  • Toxoplasma gondii infection in patients with hematological malignancies.

    abstract::Toxoplasmosis is one of the most common parasitic infections in humans, but in most cases it does not cause serious illness; this protozoan can nevertheless cause devastating disease in immunocompromised hosts such as HIV-positive individuals. Only rarely is toxoplasmosis documented in hematological patients, and amon...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s00277-004-0898-z

    authors: Pagano L,Trapè G,Putzulu R,Caramatti C,Picardi M,Nosari A,Cinieri S,Caira M,Del Favero A,GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto)-Infection Program.

    更新日期:2004-09-01 00:00:00

  • Comparison of different methods for separation and ex vivo expansion of cord blood progenitor cells.

    abstract::Umbilical cord blood is capable of hematopoietic stem cell reconstitution in children. However, the major limitation of cord blood is a relatively low content of pluripotent progenitor cells. Thus, safe engraftment for adolescents and for adults is still not predictable and a technology for ex vivo expansion of umbili...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s002770050530

    authors: Schwinger W,Benesch M,Lackner H,Kerbl R,Walcher M,Urban C

    更新日期:1999-08-01 00:00:00

  • Automated reticulocyte parameters for hereditary spherocytosis screening.

    abstract::The laboratory diagnosis of hereditary spherocytosis (HS) is based on several screening and confirmatory tests; our algorithm includes clinical features, red blood cell morphology analysis and cryohaemolysis test, and, in case of positive screening, sodium dodecyl sulphate polyacrylamide gel electrophoresis as a diagn...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s00277-014-2127-8

    authors: Lazarova E,Pradier O,Cotton F,Gulbis B

    更新日期:2014-11-01 00:00:00

  • Evaluation of neutrophil-lymphocyte ratio in patients with early-stage mycosis fungoides.

    abstract::Neutrophil-lymphocyte ratio (NLR), an indicator of inflammation, has been lately demonstrated as a prognostic factor and an indicator of disease activity in various diseases. However, the effects of NLR have not been investigated in mycosis fungoides (MF) patients yet. The aim of this study is to investigate the relat...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s00277-016-2779-7

    authors: Eren R,Nizam N,Doğu MH,Mercan S,Erdemir AV,Suyanı E

    更新日期:2016-10-01 00:00:00

  • Development of a disease-specific quality of life questionnaire for patients with aplastic anemia and/or paroxysmal nocturnal hemoglobinuria (QLQ-AA/PNH)-report on phases I and II.

    abstract::Acquired aplastic anemia (AA) and paroxysmal nocturnal hemoglobinuria (PNH) are interrelated ultra-rare diseases. Quality of life (QoL) evaluation tools used in studies for AA and PNH are unspecific and designed for cancer patients (e.g., the European Organization for Research and Treatment of Cancer Quality of Life Q...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s00277-016-2867-8

    authors: Groth M,Singer S,Niedeggen C,Petermann-Meyer A,Röth A,Schrezenmeier H,Höchsmann B,Brümmendorf TH,Panse J

    更新日期:2017-02-01 00:00:00

  • Type 2B von Willebrand's disease due to Val1316Met mutation. Heterogeneity in the same sibship.

    abstract::An analysis was conducted in four members of the same family, two of whom had a history of severe bleeding associated with type 2B von Willebrand's disease (VWD) which, although found to be due to the same mutation, nevertheless exhibited different phenotype patterns in the two subjects involved. Von Willebrand's fact...

    journal_title:Annals of hematology

    pub_type: 杂志文章

    doi:10.1007/s002770100303

    authors: Rendal E,Penas N,Larrabeiti B,Pérez A,Vale A,López-Fernández MF,Batlle J

    更新日期:2001-06-01 00:00:00